IS2720B - Afleiður 4-tetrazólýl-4-fenýlpiperidíns til þess að meðhöndla verk - Google Patents

Afleiður 4-tetrazólýl-4-fenýlpiperidíns til þess að meðhöndla verk

Info

Publication number
IS2720B
IS2720B IS7812A IS7812A IS2720B IS 2720 B IS2720 B IS 2720B IS 7812 A IS7812 A IS 7812A IS 7812 A IS7812 A IS 7812A IS 2720 B IS2720 B IS 2720B
Authority
IS
Iceland
Prior art keywords
phenylpiperidine
tetrazolyl
derivatives
treat pain
pain
Prior art date
Application number
IS7812A
Other languages
English (en)
Icelandic (is)
Other versions
IS7812A (is
Inventor
Zhengming Chen
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of IS7812A publication Critical patent/IS7812A/is
Publication of IS2720B publication Critical patent/IS2720B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IS7812A 2002-11-18 2005-04-19 Afleiður 4-tetrazólýl-4-fenýlpiperidíns til þess að meðhöndla verk IS2720B (is)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42738102P 2002-11-18 2002-11-18
US46027803P 2003-04-03 2003-04-03
US48848803P 2003-07-17 2003-07-17
US10/714,066 US7202259B2 (en) 2002-11-18 2003-11-13 Therapeutic agents useful for treating pain
PCT/US2003/036742 WO2004046132A1 (en) 2002-11-18 2003-11-17 4-tetrazolyl-4phenylpiperidine derivatives for treating pain

Publications (2)

Publication Number Publication Date
IS7812A IS7812A (is) 2005-04-19
IS2720B true IS2720B (is) 2011-02-15

Family

ID=32777221

Family Applications (2)

Application Number Title Priority Date Filing Date
IS7812A IS2720B (is) 2002-11-18 2005-04-19 Afleiður 4-tetrazólýl-4-fenýlpiperidíns til þess að meðhöndla verk
IS8913A IS8913A (is) 2002-11-18 2010-07-21 Afleiður 4-tetrazólýl-4-fenýlpiperidíns til þess að meðhöndla verk

Family Applications After (1)

Application Number Title Priority Date Filing Date
IS8913A IS8913A (is) 2002-11-18 2010-07-21 Afleiður 4-tetrazólýl-4-fenýlpiperidíns til þess að meðhöndla verk

Country Status (36)

Country Link
US (3) US7202259B2 (enExample)
EP (2) EP1803718B1 (enExample)
JP (2) JP4601429B2 (enExample)
KR (1) KR20050115221A (enExample)
CN (2) CN101648941A (enExample)
AP (1) AP2210A (enExample)
AR (1) AR047008A1 (enExample)
AT (2) ATE402167T1 (enExample)
AU (2) AU2003294313B2 (enExample)
BR (1) BR0316305A (enExample)
CA (1) CA2506242C (enExample)
CO (1) CO5690588A2 (enExample)
CR (2) CR7877A (enExample)
CY (2) CY1107682T1 (enExample)
DE (2) DE60322451D1 (enExample)
DK (2) DK1803718T3 (enExample)
EA (1) EA008621B1 (enExample)
EC (1) ECSP055840A (enExample)
ES (2) ES2285235T3 (enExample)
GE (1) GEP20084539B (enExample)
IL (1) IL209352A0 (enExample)
IS (2) IS2720B (enExample)
MA (1) MA27565A1 (enExample)
ME (1) MEP48108A (enExample)
MX (1) MXPA05004669A (enExample)
MY (1) MY135647A (enExample)
NI (1) NI200500087A (enExample)
NO (1) NO20052894D0 (enExample)
NZ (2) NZ540068A (enExample)
OA (1) OA13010A (enExample)
PT (2) PT1803718E (enExample)
RS (1) RS51047B (enExample)
SG (1) SG165998A1 (enExample)
SI (2) SI1803718T1 (enExample)
TW (2) TWI343917B (enExample)
WO (1) WO2004046132A1 (enExample)

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EP3087078B1 (en) 2013-12-26 2019-05-15 Purdue Pharma LP 7-beta-alkyl analogs of orvinols
EP3086790A4 (en) 2013-12-27 2017-07-19 Purdue Pharma LP 6-substituted and 7-substituted morphinan analogs and the use thereof
CA2950567A1 (en) 2014-05-27 2015-12-03 Purdue Pharma L.P. Spirocyclic morphinans and use thereof
CA2951697A1 (en) 2014-06-13 2015-12-17 Purdue Pharma L.P. Azamophinan derivatives and use thereof
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Also Published As

Publication number Publication date
EP1562932B9 (en) 2007-09-12
MXPA05004669A (es) 2005-06-08
EA008621B1 (ru) 2007-06-29
RS20050375A (sr) 2007-11-15
PT1803718E (pt) 2008-09-26
TW200819436A (en) 2008-05-01
EA200500726A1 (ru) 2005-10-27
DK1803718T3 (da) 2008-10-27
JP2010163452A (ja) 2010-07-29
AU2010246411A1 (en) 2010-12-16
MEP48108A (en) 2011-02-10
IS7812A (is) 2005-04-19
ES2312150T3 (es) 2009-02-16
US7687518B2 (en) 2010-03-30
CR11037A (es) 2009-10-29
WO2004046132A1 (en) 2004-06-03
US20100069437A1 (en) 2010-03-18
PT1562932E (pt) 2007-07-02
EP1562932B1 (en) 2007-04-04
US8026254B2 (en) 2011-09-27
GEP20084539B (en) 2008-11-25
EP1803718A1 (en) 2007-07-04
TW200418828A (en) 2004-10-01
US20040152689A1 (en) 2004-08-05
DE60322451D1 (de) 2008-09-04
DK1562932T3 (da) 2007-08-13
AP2005003297A0 (en) 2005-06-30
CY1108422T1 (el) 2014-04-09
EP1803718B1 (en) 2008-07-23
RS51047B (sr) 2010-10-31
ATE358674T1 (de) 2007-04-15
MA27565A1 (fr) 2005-10-03
NI200500087A (es) 2007-07-24
US7202259B2 (en) 2007-04-10
CO5690588A2 (es) 2006-10-31
SG165998A1 (en) 2010-11-29
JP4601429B2 (ja) 2010-12-22
IL209352A0 (en) 2011-01-31
KR20050115221A (ko) 2005-12-07
BR0316305A (pt) 2005-09-27
CA2506242A1 (en) 2004-06-03
CN1711256A (zh) 2005-12-21
CN101648941A (zh) 2010-02-17
TWI343917B (en) 2011-06-21
US20070179141A1 (en) 2007-08-02
ATE402167T1 (de) 2008-08-15
NZ572685A (en) 2010-06-25
DE60313021D1 (de) 2007-05-16
CA2506242C (en) 2011-07-05
AR047008A1 (es) 2006-01-04
AU2003294313A1 (en) 2004-06-15
IS8913A (is) 2010-07-21
CR7877A (es) 2005-11-30
NZ540068A (en) 2007-07-27
AP2210A (en) 2011-02-25
OA13010A (en) 2006-11-10
HK1086829A1 (zh) 2006-09-29
JP2006525944A (ja) 2006-11-16
CY1107682T1 (el) 2013-04-18
NO20052894L (no) 2005-06-14
SI1562932T1 (sl) 2007-08-31
MY135647A (en) 2008-06-30
AU2003294313B2 (en) 2010-08-26
CN100567288C (zh) 2009-12-09
ECSP055840A (es) 2005-08-11
EP1562932A1 (en) 2005-08-17
SI1803718T1 (sl) 2008-12-31
DE60313021T2 (de) 2007-12-13
ES2285235T3 (es) 2007-11-16
NO20052894D0 (no) 2005-06-14

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