IS1812B - Meðferðaefnasambönd, lyfjafræðilega hæf sölt og samsetningar sem innihalda efnasamböndin, ásamt notkun þeirra - Google Patents

Meðferðaefnasambönd, lyfjafræðilega hæf sölt og samsetningar sem innihalda efnasamböndin, ásamt notkun þeirra

Info

Publication number
IS1812B
IS1812B IS4394A IS4394A IS1812B IS 1812 B IS1812 B IS 1812B IS 4394 A IS4394 A IS 4394A IS 4394 A IS4394 A IS 4394A IS 1812 B IS1812 B IS 1812B
Authority
IS
Iceland
Prior art keywords
compounds
pharmaceutically acceptable
acceptable salts
compositions containing
therapeutic compounds
Prior art date
Application number
IS4394A
Other languages
English (en)
Other versions
IS4394A (is
Inventor
Dawes Chamberlain Stanley
Walter Koszalka George
Original Assignee
The Wellcome Foundation Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Wellcome Foundation Limited filed Critical The Wellcome Foundation Limited
Publication of IS4394A publication Critical patent/IS4394A/is
Publication of IS1812B publication Critical patent/IS1812B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IS4394A 1994-07-07 1996-12-09 Meðferðaefnasambönd, lyfjafræðilega hæf sölt og samsetningar sem innihalda efnasamböndin, ásamt notkun þeirra IS1812B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9413724A GB9413724D0 (en) 1994-07-07 1994-07-07 Therapeutic nucleosides
PCT/GB1995/001597 WO1996001833A1 (en) 1994-07-07 1995-07-06 Therapeutic compounds

Publications (2)

Publication Number Publication Date
IS4394A IS4394A (is) 1996-12-09
IS1812B true IS1812B (is) 2002-05-15

Family

ID=10757983

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4394A IS1812B (is) 1994-07-07 1996-12-09 Meðferðaefnasambönd, lyfjafræðilega hæf sölt og samsetningar sem innihalda efnasamböndin, ásamt notkun þeirra

Country Status (44)

Country Link
US (4) US6077832A (is)
EP (1) EP0769017B1 (is)
JP (1) JP3225045B2 (is)
KR (1) KR100376075B1 (is)
CN (2) CN1052010C (is)
AP (1) AP736A (is)
AT (1) ATE193298T1 (is)
AU (1) AU702248B2 (is)
BG (1) BG63435B1 (is)
BR (1) BR9508237A (is)
CY (1) CY2249B1 (is)
CZ (1) CZ290800B6 (is)
DE (1) DE69517172T2 (is)
DK (1) DK0769017T3 (is)
EE (1) EE03568B1 (is)
ES (1) ES2147294T3 (is)
FI (1) FI117629B (is)
GB (1) GB9413724D0 (is)
GE (1) GEP20002298B (is)
GR (1) GR3033744T3 (is)
HK (1) HK1003711A1 (is)
HR (1) HRP950382B1 (is)
HU (1) HU227679B1 (is)
IL (1) IL114492A (is)
IS (1) IS1812B (is)
MD (1) MD1838G2 (is)
MX (1) MX9606732A (is)
MY (1) MY117892A (is)
NO (1) NO308854B1 (is)
NZ (1) NZ288722A (is)
OA (1) OA10339A (is)
PL (1) PL181136B1 (is)
PT (1) PT769017E (is)
RO (1) RO117699B1 (is)
RU (1) RU2145963C1 (is)
SA (1) SA95160202B1 (is)
SK (1) SK282046B6 (is)
TJ (1) TJ270B (is)
TR (1) TR199500832A2 (is)
TW (1) TW418196B (is)
UA (1) UA66744C2 (is)
WO (1) WO1996001833A1 (is)
YU (1) YU49443B (is)
ZA (1) ZA955644B (is)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
DE69624827T2 (de) * 1995-08-18 2003-09-04 Univ Michigan Ann Arbor 5'-substitutierte-ribofuranosyl benzimidazolen als antivirale.
GB9518465D0 (en) * 1995-09-09 1995-11-08 Smithkline Beecham Seiyaku Kk Pharmaceuticals
GB9600142D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Chemical compounds
GB9600143D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Therapeutic compounds
US6214801B1 (en) 1996-01-23 2001-04-10 The Regents Of The University Of Michigan Imidazo[1,2-a]pyridine C-nucleosides as antiviral agents
US6576133B2 (en) 1996-11-13 2003-06-10 Transgenomic, Inc Method and system for RNA analysis by matched ion polynucleotide chromatography
US6475388B1 (en) 1996-11-13 2002-11-05 Transgenomic, Inc. Method and system for RNA analysis by matched ion polynucleotide chromatography
GB2319961A (en) * 1996-12-07 1998-06-10 Glaxo Group Ltd Pharmaceutical composition for treatment of restenosis
JP2001512453A (ja) 1997-02-13 2001-08-21 グラックス グループ リミテッド ベンゾイミダゾール誘導体
NZ501415A (en) 1997-06-10 2001-10-26 Glaxo Group Ltd Benzimidazole derivatives (optionally with saccharide substituents) useful for the treatment or prophylaxis of viral infections (particularly herpes, cytomegalovirus and Hepatitis B) or for the treatment or prophylaxis of restenosis
PL338454A1 (en) 1997-07-30 2000-11-06 Univ Michigan Lixofuranosilbenzimidazoles as antiviral agents
US6258264B1 (en) 1998-04-10 2001-07-10 Transgenomic, Inc. Non-polar media for polynucleotide separations
GB9807355D0 (en) * 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB9807354D0 (en) * 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
US6277830B1 (en) * 1998-10-16 2001-08-21 Schering Corporation 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
GB0008939D0 (en) * 2000-04-11 2000-05-31 Glaxo Group Ltd Process for preparing substituted benzimidazole compounds
EP1644011A1 (en) 2003-06-25 2006-04-12 Stephen F. Badylak Conditioned matrix compositions for tissue restoration
ES2377937T3 (es) * 2003-12-26 2012-04-03 Kissei Pharmaceutical Co., Ltd. Derivados de benzimidazol y usos médicos de los mismos
WO2006115137A1 (ja) * 2005-04-22 2006-11-02 Kissei Pharmaceutical Co., Ltd. ２－アミノベンズイミダゾール誘導体及びその医薬用途
EA008737B1 (ru) * 2005-12-07 2007-08-31 Леонид Андреевич Кожемякин Средство для профилактики и лечения конъюнктивитов и кератитов различной этиологии (варианты), способ его применения
US8940707B2 (en) * 2010-10-28 2015-01-27 Viropharma Incorporated Maribavir isomers, compositions, methods of making and methods of using
US8541391B2 (en) 2010-10-28 2013-09-24 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl-1H-benzimidazole
US8546344B2 (en) 2010-10-28 2013-10-01 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl)-1H-benzimidazole
WO2012138907A2 (en) * 2011-04-05 2012-10-11 Translational Genomics Research Institute Solid forms of curcumin
EP2867010A1 (en) 2012-06-29 2015-05-06 The Procter & Gamble Company Textured fibrous webs, apparatus and methods for forming textured fibrous webs
US9650376B2 (en) 2013-03-15 2017-05-16 Knopp Biosciences Llc Imidazo(4,5-B) pyridin-2-yl amides as KV7 channel activators
US9481653B2 (en) 2014-09-12 2016-11-01 Knopp Biosciences Llc Benzoimidazol-1,2-yl amides as Kv7 channel activators
WO2016086060A1 (en) * 2014-11-26 2016-06-02 The J. David Gladstone Institutes Methods for treating a cytomegalovirus infection
RU2629670C2 (ru) * 2016-08-04 2017-08-31 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) 2-Амино-5,6-дифтор-1-(бета-D-рибофуранозил)-бензимидазол, способ получения и противовирусная активность его в отношении вируса герпеса простого 1-го типа
MX2020009693A (es) 2018-03-19 2021-01-08 Knopp Biosciences Llc Composiciones y metodos de uso de los activadores del canal kv7.
JP7376108B2 (ja) * 2020-06-23 2023-11-08 バイオメトリックス テクノロジーズ インコーポレイテッド 新規なベンズイミダゾール誘導体、その製造方法及びその抗癌剤または抗ウイルス剤としての用途
WO2024081308A1 (en) 2022-10-12 2024-04-18 Takeda Pharmaceutical Company Limited Method of preparing maribavir
WO2024103979A1 (zh) * 2022-11-17 2024-05-23 北京凯因科技股份有限公司 一种抑制疱疹病毒的化合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3399987A (en) * 1965-08-02 1968-09-03 United States Borax Chem 2-alkylaminobenzimidazoles as herbicides
CH443777A (de) * 1965-08-06 1968-02-15 Agripat Sa Verfahren zum Schützen textiler Keratinfasern vor Insektenfrass und Mittel zur Durchführung dieses Verfahrens
US3655901A (en) * 1970-07-30 1972-04-11 Merck & Co Inc Method of inhibiting the formation of phenylethanalamine-n-methyl transferase with 2-aminobenzimidazoles
DE2130030A1 (de) * 1971-06-18 1972-12-21 Bayer Ag Fungizide und bakterizide Mittel
US4002623A (en) * 1974-08-07 1977-01-11 Pfizer Inc. Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines
FR2549938B1 (fr) * 1983-07-25 1987-08-07 Fonderie Soc Gen De Bruleur a premelange gazeux et chaudiere equipee d'un tel bruleur
FR2551442B1 (fr) * 1983-09-05 1987-04-30 Centre Nat Rech Scient Nouveaux derives furaniques, leur preparation et leur application
DK405988A (da) * 1987-07-29 1989-01-30 Hoffmann La Roche Benzimidazolderivater
IT1226100B (it) * 1988-07-07 1990-12-10 Dompe Farmaceutici Spa Derivati benzimidazolici farmacologicamente attivi.
SE9003151D0 (sv) * 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
US5248672A (en) * 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
WO1992018517A1 (en) * 1991-04-17 1992-10-29 Yale University Method of treating or preventing hepatitis b virus
ZA923640B (en) * 1991-05-21 1993-02-24 Iaf Biochem Int Processes for the diastereoselective synthesis of nucleosides
GB9205071D0 (en) * 1992-03-09 1992-04-22 Wellcome Found Therapeutic nucleosides
AU5447094A (en) * 1992-10-21 1994-05-09 Regents Of The University Of Michigan, The Polysubstituted benzimidazoles as antiviral agents
US5399580A (en) * 1993-03-08 1995-03-21 Burroughs Wellcome Co. Therapeutic nucleosides-uses
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
JP6217655B2 (ja) * 2015-01-15 2017-10-25 トヨタ自動車株式会社 電力変換装置

Also Published As

Publication number Publication date
US6307043B1 (en) 2001-10-23
ATE193298T1 (de) 2000-06-15
JPH10502356A (ja) 1998-03-03
MX9606732A (es) 1997-04-30
GR3033744T3 (en) 2000-10-31
US5998605A (en) 1999-12-07
SK282046B6 (sk) 2001-10-08
GEP20002298B (en) 2000-11-25
NZ288722A (en) 1998-07-28
PL181136B1 (pl) 2001-06-29
TJ270B (en) 2000-08-07
IL114492A (en) 2002-05-23
IS4394A (is) 1996-12-09
GB9413724D0 (en) 1994-08-24
MY117892A (en) 2004-08-30
MD1838F2 (en) 2002-01-31
CN1052010C (zh) 2000-05-03
HU227679B1 (en) 2011-11-28
YU49443B (sh) 2006-03-03
DE69517172T2 (de) 2000-10-19
HUT77285A (hu) 1998-03-30
YU45095A (sh) 1999-03-04
WO1996001833A1 (en) 1996-01-25
CN1159194A (zh) 1997-09-10
EP0769017B1 (en) 2000-05-24
EE03568B1 (et) 2001-12-17
HK1003711A1 (en) 1998-11-06
ES2147294T3 (es) 2000-09-01
US6077832A (en) 2000-06-20
TR199500832A2 (tr) 1996-06-21
PL318062A1 (en) 1997-05-12
BR9508237A (pt) 1999-06-01
NO970040L (no) 1997-01-29
RU2145963C1 (ru) 2000-02-27
CZ4097A3 (en) 1997-08-13
ZA955644B (en) 1997-01-06
UA66744C2 (en) 2004-06-15
OA10339A (en) 1997-10-07
HRP950382A2 (en) 1997-08-31
FI970032A0 (fi) 1997-01-03
CN1236616A (zh) 1999-12-01
NO308854B1 (no) 2000-11-06
HU9700034D0 (en) 1997-02-28
FI117629B (fi) 2006-12-29
EE9700013A (et) 1997-06-16
HRP950382B1 (en) 2000-12-31
IL114492A0 (en) 1995-11-27
SA95160202B1 (ar) 2005-04-16
DK0769017T3 (da) 2000-09-11
AU2805195A (en) 1996-02-09
BG63435B1 (bg) 2002-01-31
CY2249B1 (en) 2003-07-04
US20010003744A1 (en) 2001-06-14
FI970032A (fi) 1997-01-03
AP736A (en) 1999-03-09
CZ290800B6 (cs) 2002-10-16
TW418196B (en) 2001-01-11
NO970040D0 (no) 1997-01-06
EP0769017A1 (en) 1997-04-23
KR100376075B1 (ko) 2004-02-18
AU702248B2 (en) 1999-02-18
AP9600895A0 (en) 1997-01-31
BG101118A (en) 1998-04-30
PT769017E (pt) 2000-09-29
RO117699B1 (ro) 2002-06-28
MD1838G2 (ro) 2002-08-31
JP3225045B2 (ja) 2001-11-05
DE69517172D1 (de) 2000-06-29
SK168896A3 (en) 1997-09-10

Similar Documents

Publication Publication Date Title
IS4394A (is) Meðferðaefnasambönd, lyfjafræðilega hæf sölt og samsetningar sem innihalda efnasamböndin, ásamt notkun þeirra
NL300952I2 (nl) Peramivir en farmaceutisch aanvaardbare zouten daarvan
NO20053106D0 (no) Oral, analgesisk doseringsform med forlenget frigivelse.
EE200000468A (et) Ühendid, nende kasutamine ja farmatseutiline kompositsioon
PL348349A1 (en) Antrhranilic acid amides and the use thereof as medicaments
IS3878A (is) Imidazodiazepines efnasambönd, framleiðsla þeirraog notkun sem lyfja
NO975831L (no) Nytt farmasöytisk preparat med anestetisk virkning
GB9515775D0 (en) Piperidine derivatives and their use as therapeutic agents
EP0518818A3 (en) Arylethers, their manufacture and use as medicament
ITRM920412A1 (it) Eteroprostanoidi, procedimento per la loro preparazione e loro impiego terapeutico.
HUP0102585A3 (en) Thienylazolylalcoxyethanamin derivatives preparation the same and their use as medicaments
PL317613A1 (en) Substituted aryloalkylothioalkyl thiopyridines for fighting against heliobacter
NO940130D0 (no) Benzimidazolderivater, fremgangsmaate for deres fremstilling og te rapeutisk anvendelse derav
FI964212A0 (fi) Röntgenvarjoainekoostumuksia, jotka sisältävät farmaseuttisesti hyväksyttäviä savia
NO308213B1 (no) Substituerte indanylidinacetylguanidiner, deres anvendelse og medikamenter inneholdende forbindelsene
DE68906245D1 (de) Therapeutisches mittel gegen aids.
GB9816897D0 (en) Therapeutic use
GB9812662D0 (en) Therapeutic use
GB9810920D0 (en) Therapeutic use
HU9600660D0 (en) Butenol-triazolyl derivatives, their manufacture and use as microbicides
GB9821179D0 (en) Therapeutic use
GB9423948D0 (en) Heterocyclic compounds, their preparation and their therapeutic use
GB9812664D0 (en) Therapeutic use
GB9802622D0 (en) Compounds and their therapeutic use
IS4909A (is) Spíró-píperidín afleiður og notkun þeirra sem lyfjafræðilegra miðla