IS3878A - Imidazodiazepines efnasambönd, framleiðsla þeirraog notkun sem lyfja - Google Patents

Imidazodiazepines efnasambönd, framleiðsla þeirraog notkun sem lyfja

Info

Publication number
IS3878A
IS3878A IS3878A IS3878A IS3878A IS 3878 A IS3878 A IS 3878A IS 3878 A IS3878 A IS 3878A IS 3878 A IS3878 A IS 3878A IS 3878 A IS3878 A IS 3878A
Authority
IS
Iceland
Prior art keywords
imidazodiazepines
drugs
compounds
preparation
imidazodiazepines compounds
Prior art date
Application number
IS3878A
Other languages
English (en)
Inventor
Borer René
Gassner Walter
Gerecke Max
Kyburz Emilio
Original Assignee
F.Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag
Publication of IS3878A publication Critical patent/IS3878A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
IS3878A 1991-06-17 1992-06-12 Imidazodiazepines efnasambönd, framleiðsla þeirraog notkun sem lyfja IS3878A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH179191 1991-06-17
CH114092 1992-04-08

Publications (1)

Publication Number Publication Date
IS3878A true IS3878A (is) 1992-12-18

Family

ID=25686778

Family Applications (1)

Application Number Title Priority Date Filing Date
IS3878A IS3878A (is) 1991-06-17 1992-06-12 Imidazodiazepines efnasambönd, framleiðsla þeirraog notkun sem lyfja

Country Status (15)

Country Link
US (1) US5387585A (is)
EP (1) EP0519307A3 (is)
JP (1) JPH078869B2 (is)
KR (1) KR930000517A (is)
AU (1) AU655472B2 (is)
CA (1) CA2069382A1 (is)
CZ (1) CZ185092A3 (is)
FI (1) FI922827A (is)
HU (1) HU9201929D0 (is)
IE (1) IE921945A1 (is)
IL (1) IL102175A0 (is)
IS (1) IS3878A (is)
NO (1) NO922367L (is)
NZ (1) NZ243091A (is)
TW (1) TW201311B (is)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW349100B (en) * 1994-11-11 1999-01-01 Hoffmann La Roche Oxazolyl- and thiazolylimidazo-benzo- and thienodiazepines
JPH10298078A (ja) * 1997-05-06 1998-11-10 Mitsubishi Chem Corp 抗不安薬
TWI239333B (en) 2000-11-16 2005-09-11 Hoffmann La Roche Benzodiazepine derivatives as GABA A receptor modulators
US6686352B2 (en) 2001-05-18 2004-02-03 Hoffmann-La Roche Inc. Substituted imidazo [1,5-a] pyrimido [5,4-d] [1] benzazepine derivatives
EP1461323B1 (en) * 2001-06-12 2013-10-09 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
BRPI0517412A (pt) * 2004-10-12 2008-10-07 Hoffmann La Roche derivados de benzodiazepina substituìdos
NZ554556A (en) * 2004-10-20 2009-11-27 Hoffmann La Roche Halogen substituted imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]benzodiazepines
AU2005299032B2 (en) * 2004-10-20 2011-11-17 F. Hoffmann-La Roche Ag Imidazo-benzodiazepine derivatives
DE602005007265D1 (de) * 2004-12-14 2008-07-10 Hoffmann La Roche Tetrazyklische imidazobenzodiazepine als gaba-rezeptormodulatoren
BRPI0617204A2 (pt) 2005-10-11 2011-07-19 Hoffmann La Roche derivados de imidazo benzodiazepina
US9322831B2 (en) 2008-09-23 2016-04-26 The Johns Hopkins University DDX3 as a biomarker for cancer and methods related thereto
CA2738650C (en) * 2008-09-23 2017-07-04 Johns Hopkins University Fused diimidazodiazepine compounds and methods of use and manufacture thereof
AU2014240289B2 (en) * 2008-09-23 2015-12-03 The Johns Hopkins University Fused diimidazodiazepine compounds and methods of use and manufacture thereof
NO3034079T3 (is) 2010-11-15 2018-06-09
PL3363790T3 (pl) 2013-09-06 2020-07-27 Aurigene Discovery Technologies Limited Pochodne 1,2,4-oksadiazolu jako immunomodulatory
MX2016007808A (es) * 2013-12-20 2016-09-07 Agenebio Inc Derivados de benzodiazepina, composiciones, y metodos para tratar el deterioro congnitivo.
KR20170123317A (ko) * 2015-03-10 2017-11-07 오리진 디스커버리 테크놀로지스 리미티드 면역조절제로서의 3-치환된-1,2,4-옥사다이아졸 및 티아다이아졸 화합물
SG10202108921VA (en) 2015-03-10 2021-09-29 Aurigene Discovery Tech Ltd 1,2,4-oxadiazole and thiadiazole compounds as immunomodulators
IL256354B (en) 2015-06-19 2022-09-01 Agenebio Inc History of benzodiazepines, preparations and their use for the treatment of cognitive impairment
SG11201804901WA (en) 2015-12-22 2018-07-30 SHY Therapeutics LLC Compounds for the treatment of cancer and inflammatory disease
BR112019012821A2 (pt) 2016-12-19 2019-11-26 Agenebio Inc derivados de benzodiazepina, composições e métodos para o tratamento do comprometimento cognitivo
US20180170941A1 (en) * 2016-12-19 2018-06-21 Agenebio, Inc. Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
EA201992780A1 (ru) 2017-06-21 2020-06-02 ШАЙ ТЕРАПЬЮТИКС ЭлЭлСи Соединения, которые взаимодействуют с суперсемейством ras, для лечения рака, воспалительных заболеваний, ras-опатий и фиброзного заболевания
WO2019061324A1 (en) 2017-09-29 2019-04-04 Curis Inc. CRYSTALLINE FORMS OF IMMUNOMODULATORS
SG11202003081WA (en) 2017-10-11 2020-05-28 Aurigene Discovery Tech Ltd Crystalline forms of 3-substituted 1,2,4-oxadiazole
CN111372584A (zh) 2017-11-03 2020-07-03 奥瑞基尼探索技术有限公司 Tim-3和pd-1途径的双重抑制剂
CA3081675A1 (en) 2017-11-06 2019-05-09 Aurigene Discovery Technologies Limited Conjoint therapies for immunomodulation
EA202190076A1 (ru) 2018-06-19 2021-09-22 Эйджинбайо, Инк. Производные бензодиазепина, композиции и способы лечения когнитивных нарушений

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
CA1252462A (en) * 1984-01-19 1989-04-11 Walter Hunkeler Imidazodiazepine derivatives
US4897392A (en) * 1989-07-03 1990-01-30 Hoechst-Roussel Pharmaceuticals, Inc. 4H-indolo(1,2-d)(1,2,4)triazolo(4,3-A)(1,4)benzodiazepines
DK443589D0 (da) * 1989-09-08 1989-09-08 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK41191D0 (da) * 1991-03-07 1991-03-07 Novo Nordisk As Heterocycliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
HU9201929D0 (en) 1992-08-28
TW201311B (is) 1993-03-01
EP0519307A2 (de) 1992-12-23
KR930000517A (ko) 1993-01-15
NO922367D0 (no) 1992-06-16
NO922367L (no) 1992-12-18
AU1823492A (en) 1992-12-24
IL102175A0 (en) 1993-01-14
AU655472B2 (en) 1994-12-22
JPH078869B2 (ja) 1995-02-01
FI922827A (fi) 1992-12-18
NZ243091A (en) 1994-11-25
JPH05202051A (ja) 1993-08-10
US5387585A (en) 1995-02-07
EP0519307A3 (en) 1993-04-21
CZ185092A3 (en) 1993-12-15
IE921945A1 (en) 1992-12-30
CA2069382A1 (en) 1992-12-18
FI922827A0 (fi) 1992-06-17

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