IN2014DE02197A - - Google Patents
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- Publication number
- IN2014DE02197A IN2014DE02197A IN2197DE2014A IN2014DE02197A IN 2014DE02197 A IN2014DE02197 A IN 2014DE02197A IN 2197DE2014 A IN2197DE2014 A IN 2197DE2014A IN 2014DE02197 A IN2014DE02197 A IN 2014DE02197A
- Authority
- IN
- India
- Prior art keywords
- hot
- melt
- hpmcas
- drug
- melt extrusion
- Prior art date
Links
- ZUAAPNNKRHMPKG-UHFFFAOYSA-N acetic acid;butanedioic acid;methanol;propane-1,2-diol Chemical compound OC.CC(O)=O.CC(O)CO.OC(=O)CCC(O)=O ZUAAPNNKRHMPKG-UHFFFAOYSA-N 0.000 abstract 5
- 239000012943 hotmelt Substances 0.000 abstract 5
- 238000009474 hot melt extrusion Methods 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 238000002844 melting Methods 0.000 abstract 2
- 230000008018 melting Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013167572 | 2013-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DE02197A true IN2014DE02197A (enExample) | 2015-06-19 |
Family
ID=51225402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2197DE2014 IN2014DE02197A (enExample) | 2013-08-12 | 2014-08-01 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11090295B2 (enExample) |
| EP (1) | EP2837391B1 (enExample) |
| JP (1) | JP6162662B2 (enExample) |
| KR (1) | KR102089112B1 (enExample) |
| CN (1) | CN104371030B (enExample) |
| IN (1) | IN2014DE02197A (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6203702B2 (ja) * | 2014-11-18 | 2017-09-27 | 信越化学工業株式会社 | ヒプロメロース酢酸エステルコハク酸エステルを用いたスプレードライ用溶液及び固体分散体の製造方法 |
| US10604588B2 (en) | 2016-04-05 | 2020-03-31 | Shin-Etsu Chemical Co., Ltd. | Hypromellose acetate succinate powder excellent in dissolved state and production method thereof, and production methods for composition for solid dispersion, coating composition, drug-containing particle, and solid preparation |
| WO2017032908A1 (en) * | 2016-07-08 | 2017-03-02 | Synthon B.V. | Pharmaceutical composition comprising amorphous posaconazole |
| JP6683561B2 (ja) * | 2016-07-12 | 2020-04-22 | 信越化学工業株式会社 | 腸溶性硬カプセル用組成物及び腸溶性硬カプセルの製造方法 |
| JP6644656B2 (ja) | 2016-08-29 | 2020-02-12 | 信越化学工業株式会社 | ヒプロメロース酢酸エステルコハク酸エステルの製造方法 |
| JP6742197B2 (ja) * | 2016-08-29 | 2020-08-19 | 信越化学工業株式会社 | ヒプロメロースフタル酸エステルの製造方法 |
| US20190038754A1 (en) | 2017-08-07 | 2019-02-07 | SE Tylose, USA, Inc. | Pharmaceutical composition in solid extruded form |
| TR201722852A2 (tr) * | 2017-12-29 | 2019-07-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Mesalazi̇ni̇n oral farmasöti̇k kompozi̇syonlari |
| JP6905035B2 (ja) * | 2019-11-29 | 2021-07-21 | Nissha株式会社 | 可食性フィルムの製造方法、フィルム製剤及び可食性フィルム |
| JP7399061B2 (ja) * | 2020-10-01 | 2023-12-15 | 信越化学工業株式会社 | ヒドロキシプロピルメチルセルロースフタレートの製造方法 |
| JP2025019010A (ja) * | 2023-07-26 | 2025-02-06 | 信越化学工業株式会社 | ヒドロキシプロピルメチルセルロースアセテートサクシネート粉末及びその製造方法 |
| CN120938940A (zh) * | 2025-10-15 | 2025-11-14 | 成都药宜立康医药科技有限公司 | 一种苯磺酸美洛加巴林药物组合物及其制备方法 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4226981A (en) | 1977-09-28 | 1980-10-07 | Shin-Etsu Chemical Co., Ltd. | Ether-ester derivatives of cellulose and their applications |
| JPS5951562B2 (ja) | 1977-10-25 | 1984-12-14 | 信越化学工業株式会社 | セルロ−スエ−テルの酸性サクシニルおよび脂肪族モノアシル混成エステルの製造方法 |
| JPS5535031A (en) * | 1978-09-04 | 1980-03-11 | Shin Etsu Chem Co Ltd | Enteric coating composition |
| JP2528706B2 (ja) | 1988-05-30 | 1996-08-28 | ゼリア新薬工業株式会社 | ジヒドロピリジン化合物の製剤組成物 |
| JP2925346B2 (ja) | 1991-03-18 | 1999-07-28 | 田辺製薬株式会社 | 腸溶性製剤およびその製法 |
| JP2527107B2 (ja) | 1991-04-16 | 1996-08-21 | 日本新薬株式会社 | 固体分散体の製造方法 |
| JPH0920663A (ja) * | 1995-07-07 | 1997-01-21 | Teikoku Seiyaku Co Ltd | イブジラストを含有する徐放性細粒剤およびその製法 |
| JP4290817B2 (ja) | 1999-07-29 | 2009-07-08 | 株式会社金門製作所 | ガスメータ |
| PT1207866E (pt) * | 1999-08-31 | 2005-02-28 | Gruenenthal Gmbh | Forma de administracao retardada contendo sacarinato de tramadol |
| PT1239831E (pt) | 1999-12-23 | 2013-01-23 | Mayne Pharma International Pty Ltd | Composições farmacêuticas melhoradas para fármacos fracamente solúveis |
| JP3552160B2 (ja) * | 2000-01-14 | 2004-08-11 | 信越化学工業株式会社 | 低置換度ヒドロキシプロピルセルロース粒子の形成方法 |
| JPWO2003077827A1 (ja) | 2002-03-19 | 2005-07-14 | 日本新薬株式会社 | 医薬固体分散体の製造方法 |
| KR100454394B1 (ko) | 2002-03-27 | 2004-10-26 | 이원희 | 맥파검출장치 |
| GB0418791D0 (en) | 2004-08-23 | 2004-09-22 | Glaxo Group Ltd | Novel process |
| JP5576922B2 (ja) * | 2006-04-20 | 2014-08-20 | 信越化学工業株式会社 | 腸溶性固体分散体を含んでなる固形製剤 |
| JP2007308480A (ja) * | 2006-04-20 | 2007-11-29 | Shin Etsu Chem Co Ltd | 腸溶性固体分散体を含んでなる固形製剤 |
| CN101125204A (zh) * | 2006-08-08 | 2008-02-20 | 信越化学工业株式会社 | 含有固体分散体的固体制剂及其制备方法 |
| WO2008138755A2 (en) * | 2007-05-11 | 2008-11-20 | F. Hoffmann-La Roche Ag | Pharmaceutical compositions for poorly soluble drugs |
| JP2009089982A (ja) * | 2007-10-11 | 2009-04-30 | Ohara Yakuhin Kogyo Kk | 打錠用造粒物の造粒方法 |
| WO2009129301A2 (en) | 2008-04-15 | 2009-10-22 | Schering Corporation | Oral pharmaceutical compositions in a molecular solid dispersion |
| TWI388324B (zh) * | 2008-04-15 | 2013-03-11 | Schering Corp | 含有泊沙康唑(posaconazole)之高密度組合物及包含該組合物之調配物 |
| WO2009132208A1 (en) | 2008-04-24 | 2009-10-29 | Evestra, Inc. | Oral contraceptive dosage forms comprising a progestogen dispersed in an enteric polymer and further comprising an estrogen |
| CN102988318A (zh) | 2008-11-25 | 2013-03-27 | 田边三菱制药株式会社 | 口腔速崩片及其制备方法 |
| MX2011008303A (es) * | 2009-04-03 | 2011-11-29 | Plexxikon Inc | Composiciones del acido propano-1-sulfonico {3-[5-(4-cloro-fenil)- 1h-pirrolo [2,3-b]-piridina-3-carbonil]-2,4-difluoro-fenil}-amida y el uso de las mismas. |
| JP5324302B2 (ja) * | 2009-04-22 | 2013-10-23 | 信越化学工業株式会社 | 高成型性、高流動性低置換度ヒドロキシプロピルセルロースおよびそれを含む固形製剤 |
| FR2945947B1 (fr) * | 2009-05-29 | 2011-07-29 | Flamel Tech Sa | Compositions pharmaceutiques flottantes a liberation controlee |
| EP2647648B1 (en) | 2010-12-03 | 2017-08-09 | Nippon Soda Co., Ltd. | Solid dosage form containing a low viscosity HYDROXYALKYL CELLULOSE |
| US8591944B2 (en) | 2011-03-08 | 2013-11-26 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
| KR101916010B1 (ko) | 2011-04-06 | 2018-11-08 | 다우 글로벌 테크놀로지스 엘엘씨 | 신규한 폴리사카라이드 유도체 및 제형 |
| EP2524688B1 (en) | 2011-05-11 | 2013-05-01 | ratiopharm GmbH | Composition for modified release comprising ranolazine |
| CN103083240B (zh) * | 2011-10-28 | 2015-12-09 | 沈阳药科大学 | 紫杉醇及其同系物的固体分散体及其口服制剂的制备 |
-
2014
- 2014-07-29 EP EP14178879.4A patent/EP2837391B1/en active Active
- 2014-08-01 IN IN2197DE2014 patent/IN2014DE02197A/en unknown
- 2014-08-07 KR KR1020140101712A patent/KR102089112B1/ko active Active
- 2014-08-07 US US14/453,935 patent/US11090295B2/en active Active
- 2014-08-08 CN CN201410389913.7A patent/CN104371030B/zh active Active
- 2014-08-08 JP JP2014162437A patent/JP6162662B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015057380A (ja) | 2015-03-26 |
| CN104371030A (zh) | 2015-02-25 |
| EP2837391A1 (en) | 2015-02-18 |
| US11090295B2 (en) | 2021-08-17 |
| JP6162662B2 (ja) | 2017-07-12 |
| US20150044289A1 (en) | 2015-02-12 |
| CN104371030B (zh) | 2017-08-08 |
| EP2837391B1 (en) | 2017-05-10 |
| KR102089112B1 (ko) | 2020-03-13 |
| KR20150020073A (ko) | 2015-02-25 |
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