IN2014CN04039A - - Google Patents
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- Publication number
- IN2014CN04039A IN2014CN04039A IN4039CHN2014A IN2014CN04039A IN 2014CN04039 A IN2014CN04039 A IN 2014CN04039A IN 4039CHN2014 A IN4039CHN2014 A IN 4039CHN2014A IN 2014CN04039 A IN2014CN04039 A IN 2014CN04039A
- Authority
- IN
- India
- Prior art keywords
- secretory production
- heterologous protein
- protein
- activity
- produce
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2011144497/10A RU2011144497A (ru) | 2011-11-02 | 2011-11-02 | Способ секреторного получения белка |
JP2011240745 | 2011-11-02 | ||
PCT/JP2012/078906 WO2013065869A1 (en) | 2011-11-02 | 2012-11-01 | Method for secretory production of protein |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2014CN04039A true IN2014CN04039A (es) | 2015-10-23 |
Family
ID=47222244
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN4039CHN2014 IN2014CN04039A (es) | 2011-11-02 | 2012-11-01 |
Country Status (8)
Country | Link |
---|---|
US (1) | US9187554B2 (es) |
EP (1) | EP2748340B1 (es) |
JP (1) | JP6020581B2 (es) |
KR (1) | KR101653555B1 (es) |
CN (1) | CN103946371B (es) |
AU (1) | AU2012333451B2 (es) |
IN (1) | IN2014CN04039A (es) |
WO (1) | WO2013065869A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013065772A1 (ja) | 2011-11-02 | 2013-05-10 | 味の素株式会社 | タンパク質の分泌生産法 |
EP2748340B1 (en) | 2011-11-02 | 2016-06-01 | Ajinomoto Co., Inc. | Method for secretory production of proteins |
RU2013119826A (ru) * | 2013-04-29 | 2014-11-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | Коринеформная бактерия и способ получения гетерологичных гибридных белков |
JP6519476B2 (ja) | 2013-10-23 | 2019-05-29 | 味の素株式会社 | 目的物質の製造法 |
KR20160147778A (ko) * | 2014-05-02 | 2016-12-23 | 신슈 다이가쿠 | 항체 유전자의 발현·분비 시스템 |
US10519248B2 (en) * | 2014-07-25 | 2019-12-31 | Memorial Sloan Kettering Cancer Center | Bispecific HER2 and CD3 binding molecules |
AU2016253217B2 (en) | 2015-04-24 | 2021-09-02 | Ajinomoto Co., Inc. | Method for secretory production of protein |
AU2017347016B2 (en) | 2016-10-21 | 2021-09-23 | Ajinomoto Co., Inc. | Secretory production method for protein |
JP7159867B2 (ja) * | 2016-10-21 | 2022-10-25 | 味の素株式会社 | タンパク質の分泌生産法 |
EP3601583A1 (en) | 2017-03-28 | 2020-02-05 | Ajinomoto Co., Inc. | Method for producing rna |
JP7367667B2 (ja) | 2018-02-20 | 2023-10-24 | 味の素株式会社 | Rnaサイレンシングを誘導する方法 |
JP7439749B2 (ja) | 2018-04-20 | 2024-02-28 | 味の素株式会社 | タンパク質の分泌生産法 |
EP3861109A1 (en) | 2018-10-05 | 2021-08-11 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
AU2019364829A1 (en) | 2018-10-25 | 2021-06-03 | Ajinomoto Co., Inc. | Method for secretory production of protein |
CN111909879B (zh) * | 2020-08-24 | 2023-04-28 | 江南大学 | 一种高效表达外源蛋白的谷氨酸棒杆菌诱变菌株及应用 |
WO2022178078A1 (en) | 2021-02-19 | 2022-08-25 | Theripion, Inc. | Paraoxonase fusion polypeptides and related compositions and methods |
EP4368722A1 (en) | 2021-07-07 | 2024-05-15 | Ajinomoto Co., Inc. | Method for secretory production of unnatural-amino-acid-containing protein |
Family Cites Families (39)
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JPS57134500A (en) | 1981-02-12 | 1982-08-19 | Kyowa Hakko Kogyo Co Ltd | Plasmid pcg1 |
JPS57183799A (en) | 1981-04-17 | 1982-11-12 | Kyowa Hakko Kogyo Co Ltd | Novel plasmid |
JPS5835197A (ja) | 1981-08-26 | 1983-03-01 | Kyowa Hakko Kogyo Co Ltd | プラスミドpcg2 |
JPS58192900A (ja) | 1982-05-04 | 1983-11-10 | Ajinomoto Co Inc | 複合プラスミド |
US4965197A (en) | 1987-06-12 | 1990-10-23 | Massachusetts Institute Of Technology | Coryneform expression and secretion system |
JPH01191686A (ja) | 1988-01-26 | 1989-08-01 | Mitsubishi Petrochem Co Ltd | 複合プラスミド |
US5185262A (en) | 1988-07-27 | 1993-02-09 | Mitsubishi Petrochemical Co., Ltd. | DNA fragment containing gene which encodes the function of stabilizing plasmid in host microorganism |
JP2678995B2 (ja) | 1988-09-08 | 1997-11-19 | 三菱化学株式会社 | トリプトフアンシンターゼの製造法 |
JP2973446B2 (ja) | 1990-01-11 | 1999-11-08 | 三菱化学株式会社 | 新規プラスミドベクター |
JPH07108228B2 (ja) | 1990-10-15 | 1995-11-22 | 味の素株式会社 | 温度感受性プラスミド |
JP2925776B2 (ja) | 1991-04-22 | 1999-07-28 | 三洋電機株式会社 | 吸収式冷凍機 |
JPH06502548A (ja) | 1991-07-30 | 1994-03-24 | オルサン | 特にコリネバクテリア中で用いることのできる蛋白質の発現および分泌系 |
DE69535037T2 (de) | 1994-08-26 | 2006-12-07 | Novozymes A/S | Mikrobielle transglutaminasen, ihre herstellung und ihre verwendung |
WO1996022366A1 (en) | 1995-01-19 | 1996-07-25 | Novo Nordisk A/S | Transglutaminases from oomycetes |
JPH0970291A (ja) | 1995-06-30 | 1997-03-18 | Ajinomoto Co Inc | 人工トランスポゾンを用いた遺伝子増幅方法 |
JP4035855B2 (ja) | 1996-06-05 | 2008-01-23 | 味の素株式会社 | L−リジンの製造法 |
JP3711658B2 (ja) | 1996-10-07 | 2005-11-02 | 味の素株式会社 | コリネバクテリウム・アンモニアゲネス由来の新規な細胞表層蛋白質 |
JP4168463B2 (ja) | 1996-12-05 | 2008-10-22 | 味の素株式会社 | L−リジンの製造法 |
JPH11169182A (ja) | 1997-12-10 | 1999-06-29 | Mitsubishi Chemical Corp | コリネ型細菌内で蛋白質を効率よく培地中へ分泌させる変異型分泌装置遺伝子 |
DE69938652D1 (de) * | 1998-03-06 | 2008-06-19 | Ajinomoto Kk | Gen für penicillin-bindendes protein und verfahren zur herstellung von l-glutaminsäure |
JP2000262288A (ja) | 1999-03-16 | 2000-09-26 | Ajinomoto Co Inc | コリネ型細菌の温度感受性プラスミド |
US20050244935A1 (en) | 1999-06-25 | 2005-11-03 | Basf Ag | Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport |
KR100815041B1 (ko) | 1999-08-02 | 2008-03-18 | 아처 다니엘 미드랜드 캄파니 | 아미노산 생산의 대사 공학 |
ATE532870T1 (de) | 1999-09-30 | 2011-11-15 | Ajinomoto Kk | Verfahren zur herstellung von transglutaminase |
MXPA02007154A (es) | 2000-01-21 | 2004-09-06 | Ajinomoto Kk | Procedimiento para producir l-lisina. |
DE60234247D1 (de) | 2001-03-30 | 2009-12-17 | Ajinomoto Kk | Verfahren zur sekretion und produktion von protein |
EP1548116A4 (en) * | 2002-09-30 | 2006-04-05 | Ajinomoto Kk | PROCESS FOR PRODUCING A PROTEIN MARKED BY A STABLE ISOTOPE |
DK1602722T3 (da) | 2003-03-07 | 2011-05-16 | Ajinomoto Kk | Fremgangsmåde til fremstilling af mikrobiel transglutaminase |
US7807176B2 (en) | 2004-03-19 | 2010-10-05 | Genomidea, Inc. | Polypeptide promoting vascular endothelial cell growth |
JP4760711B2 (ja) | 2004-03-31 | 2011-08-31 | 味の素株式会社 | バチルス属又はエシェリヒア属に属する細菌を使用した発酵によるプリンヌクレオシド及びヌクレオチドの製造方法 |
WO2005103278A1 (ja) | 2004-04-20 | 2005-11-03 | Ajinomoto Co., Inc. | タンパク質の製造法 |
BRPI0510919A (pt) | 2004-05-20 | 2008-05-20 | Ajinomoto Kk | bactéria produtora de ácido succìnico e processo para produzir ácido succìnico |
JP4595506B2 (ja) | 2004-11-25 | 2010-12-08 | 味の素株式会社 | L−アミノ酸生産菌及びl−アミノ酸の製造方法 |
EP1871883A1 (en) | 2005-03-02 | 2008-01-02 | Metanomics GmbH | Process for the production of fine chemicals |
US7723097B2 (en) | 2005-03-11 | 2010-05-25 | Archer-Daniels-Midland Company | Escherichia coli strains that over-produce L-threonine and processes for their production |
RU2365622C2 (ru) | 2006-12-22 | 2009-08-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | СПОСОБ ПРОДУКЦИИ ПУРИНОВЫХ НУКЛЕОЗИДОВ И НУКЛЕОТИДОВ МЕТОДОМ ФЕРМЕНТАЦИИ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Escherichia ИЛИ Bacillus |
EP2302066A4 (en) | 2008-07-09 | 2012-02-08 | Ajinomoto Kk | METHOD FOR PRODUCING AMINOHYDROXYBENZOIC ACID |
WO2013065772A1 (ja) | 2011-11-02 | 2013-05-10 | 味の素株式会社 | タンパク質の分泌生産法 |
EP2748340B1 (en) | 2011-11-02 | 2016-06-01 | Ajinomoto Co., Inc. | Method for secretory production of proteins |
-
2012
- 2012-11-01 EP EP12790980.2A patent/EP2748340B1/en active Active
- 2012-11-01 JP JP2014539576A patent/JP6020581B2/ja active Active
- 2012-11-01 WO PCT/JP2012/078906 patent/WO2013065869A1/en active Application Filing
- 2012-11-01 KR KR1020147015040A patent/KR101653555B1/ko active IP Right Grant
- 2012-11-01 IN IN4039CHN2014 patent/IN2014CN04039A/en unknown
- 2012-11-01 AU AU2012333451A patent/AU2012333451B2/en active Active
- 2012-11-01 CN CN201280054079.5A patent/CN103946371B/zh active Active
-
2014
- 2014-04-29 US US14/264,353 patent/US9187554B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR101653555B1 (ko) | 2016-09-02 |
CN103946371B (zh) | 2016-07-06 |
US9187554B2 (en) | 2015-11-17 |
AU2012333451A1 (en) | 2014-04-03 |
CN103946371A (zh) | 2014-07-23 |
EP2748340A1 (en) | 2014-07-02 |
WO2013065869A1 (en) | 2013-05-10 |
RU2014122201A (ru) | 2015-12-10 |
EP2748340B1 (en) | 2016-06-01 |
AU2012333451B2 (en) | 2015-05-21 |
JP6020581B2 (ja) | 2016-11-02 |
JP2014532424A (ja) | 2014-12-08 |
KR20140088215A (ko) | 2014-07-09 |
US20140255996A1 (en) | 2014-09-11 |
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