WO2014015841A3 - 一种利用微藻高效生产虾青素的方法 - Google Patents
一种利用微藻高效生产虾青素的方法 Download PDFInfo
- Publication number
- WO2014015841A3 WO2014015841A3 PCT/CN2013/084262 CN2013084262W WO2014015841A3 WO 2014015841 A3 WO2014015841 A3 WO 2014015841A3 CN 2013084262 W CN2013084262 W CN 2013084262W WO 2014015841 A3 WO2014015841 A3 WO 2014015841A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- algae
- astaxanthin
- micro
- efficiency production
- culture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/12—Unicellular algae; Culture media therefor
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13823422.4A EP2878676A4 (en) | 2012-07-27 | 2013-09-26 | PROCESS WITH MICROALGEN FOR THE HIGHLY EFFICIENT MANUFACTURE OF ASTAXANTHINE |
IN1606DEN2015 IN2015DN01606A (zh) | 2012-07-27 | 2013-09-26 | |
US14/417,166 US20150252391A1 (en) | 2012-07-27 | 2013-09-26 | Method using microalgae for high-efficiency production of astaxanthin |
BR112015001637A BR112015001637A2 (pt) | 2012-07-27 | 2013-09-26 | método usando microalgas para produção com eficiência elevada de astaxantina |
AU2013295436A AU2013295436A1 (en) | 2012-07-27 | 2013-09-26 | Method using micro-algae for high-efficiency production of astaxanthin |
CN201380039500.XA CN104662162A (zh) | 2013-09-26 | 2013-09-26 | 一种利用微藻高效生产虾青素的新方法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210264946.XA CN103571906B (zh) | 2012-07-27 | 2012-07-27 | 一种利用微藻高效生产虾青素的新方法 |
CN201210264946.X | 2012-07-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2014015841A2 WO2014015841A2 (zh) | 2014-01-30 |
WO2014015841A3 true WO2014015841A3 (zh) | 2014-03-20 |
Family
ID=49997905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2013/084262 WO2014015841A2 (zh) | 2012-07-27 | 2013-09-26 | 一种利用微藻高效生产虾青素的新方法 |
Country Status (7)
Country | Link |
---|---|
US (1) | US20150252391A1 (zh) |
EP (1) | EP2878676A4 (zh) |
CN (1) | CN103571906B (zh) |
AU (1) | AU2013295436A1 (zh) |
BR (1) | BR112015001637A2 (zh) |
IN (1) | IN2015DN01606A (zh) |
WO (1) | WO2014015841A2 (zh) |
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KR101725976B1 (ko) * | 2014-04-17 | 2017-04-26 | 고려대학교 산학협력단 | 고온에서 성숙포자 접종 및 철이온매개 하버-바이스 반응에 의한 해마토코쿠스 플루비알리스 내 아스타잔틴 생산량 증진방법 |
CN103966103A (zh) * | 2014-05-26 | 2014-08-06 | 临沂大学 | 利用啤酒厂废水培养雨生红球藻的培养基及培养方法 |
CN104263649A (zh) * | 2014-09-15 | 2015-01-07 | 李健 | 一种大规模微藻培养的方法 |
WO2016146803A1 (de) * | 2015-03-19 | 2016-09-22 | Basf Se | Astaxanthinzusammensetzungen (iii) |
JP2018510634A (ja) * | 2015-03-19 | 2018-04-19 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | アスタキサンチン組成物(i) |
CN105420332A (zh) * | 2015-12-10 | 2016-03-23 | 天津科技大学 | 一种雨生红球藻高产虾青素的方法 |
CN105462844B (zh) * | 2015-12-16 | 2019-05-03 | 中国科学院青岛生物能源与过程研究所 | 一种雨生红球藻细胞周期同步化的调控方法及其应用 |
CN107189946B (zh) * | 2016-03-15 | 2022-07-01 | 嘉兴泽元生物制品有限责任公司 | 一种避免微藻光抑制以提高虾青素产量的方法 |
CA3028227A1 (en) | 2016-06-30 | 2018-01-04 | Kuehnle Agrosystems, Inc. | Improved heterotrophic production methods for microbial biomass and bioproducts |
CN106316847B (zh) * | 2016-08-16 | 2019-01-15 | 集美大学 | 一种虾青素亚油酸单酯的制备方法 |
WO2018056160A1 (ja) * | 2016-09-21 | 2018-03-29 | 日本水産株式会社 | アスタキサンチンの生産方法 |
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EP3519555A1 (en) * | 2016-09-30 | 2019-08-07 | Heliae Development LLC | Methods of applying acetate toxicity and inducing acetate uptake in microalgae cultures |
US10793547B2 (en) | 2016-12-09 | 2020-10-06 | Vertex Pharmaceuticals Incorporated | Modulator of the cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator |
AU2018279646B2 (en) | 2017-06-08 | 2023-04-06 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
CA3068609A1 (en) | 2017-07-01 | 2019-01-10 | Vertex Pharmaceuticals Incorporated | Compositions and methods for treatment of cystic fibrosis |
CN107384907A (zh) * | 2017-07-13 | 2017-11-24 | 荆楚理工学院 | 一种富硒虾青素小球藻粉的制备方法 |
CA3069226A1 (en) | 2017-07-17 | 2019-01-24 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
WO2019018353A1 (en) | 2017-07-17 | 2019-01-24 | Vertex Pharmaceuticals Incorporated | METHODS OF TREATING CYSTIC FIBROSIS |
CA3078893A1 (en) | 2017-10-19 | 2019-04-25 | Vertex Pharmaceuticals Incorporated | Crystalline forms and compositions of cftr modulators |
WO2019113089A1 (en) | 2017-12-04 | 2019-06-13 | Vertex Pharmaceuticals Incorporated | Compositions for treating cystic fibrosis |
TWI810243B (zh) | 2018-02-05 | 2023-08-01 | 美商維泰克斯製藥公司 | 用於治療囊腫纖化症之醫藥組合物 |
PT3752510T (pt) | 2018-02-15 | 2023-03-15 | Vertex Pharma | Macrociclos como moduladores do regulador de condutância de transmembrana da fibrose cística, suas composições farmacêuticas, seu uso no tratamento da fibrose cística e processos para produzi-los |
WO2019195739A1 (en) | 2018-04-05 | 2019-10-10 | Alexander Russell Abela | Modulators of cystic fibrosis transmembrane conductance regulator |
US11414439B2 (en) | 2018-04-13 | 2022-08-16 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator |
CN108504619B (zh) * | 2018-06-06 | 2021-06-01 | 中国科学院海洋研究所 | 一种缓解雨生红球藻光抑制的方法 |
IT201800006555A1 (it) * | 2018-06-21 | 2019-12-21 | Procedimento per la coltivazione di alghe, preferibilmente di microalghe | |
CN109566393A (zh) * | 2018-12-14 | 2019-04-05 | 浙江海洋大学 | 用于提取多糖的海藻的培养方法 |
JP7535103B2 (ja) * | 2019-09-23 | 2024-08-15 | バイオアルゴ(ダブリュエフ)カンパニー,リミテッド | ヘマトコッカス・プルビアリス(Haematococcus pluvialis)を培養して、アスタキサンチンを産生する方法 |
CN114729297B (zh) * | 2019-09-23 | 2024-04-12 | 山东拜昂生物技术有限公司 | 一种异养培养雨生红球藻生产虾青素的方法 |
WO2022194399A1 (en) | 2020-07-13 | 2022-09-22 | Idorsia Pharmaceuticals Ltd | Macrocycles as cftr modulators |
CN111979097A (zh) * | 2020-09-04 | 2020-11-24 | 清华大学 | 一种微藻培养用光生物反应器 |
CN112239727B (zh) * | 2020-10-15 | 2022-04-01 | 大连理工大学 | 一种基于人工智能微藻混合系统培养微藻的方法 |
KR102535358B1 (ko) * | 2021-03-30 | 2023-05-26 | 고려대학교 산학협력단 | 초음파 자극의 도입을 통한 미세조류 유래 고부가 가치 물질 생합성 증대법 |
CN113717917A (zh) * | 2021-06-30 | 2021-11-30 | 中国海洋大学 | 一种雨生红球藻纯种培养的联合抗生素施用方法 |
CN113817793A (zh) * | 2021-09-14 | 2021-12-21 | 国青(浙江)科学研究有限公司 | 一种叶黄素提高雨生红球藻中虾青素含量的生产工艺 |
CN114214386A (zh) * | 2021-12-13 | 2022-03-22 | 广东百睿盈科生物科技有限公司 | 一种异养培养小球藻生产虾青素的方法 |
CN114214202B (zh) * | 2021-12-27 | 2024-02-13 | 广西源藻生物科技有限公司 | 异养-光诱导串联培养微藻联产叶黄素和蛋白质的方法 |
WO2024056791A1 (en) | 2022-09-15 | 2024-03-21 | Idorsia Pharmaceuticals Ltd | Combination of macrocyclic cftr modulators with cftr correctors and / or cftr potentiators |
WO2024056779A1 (en) | 2022-09-15 | 2024-03-21 | Idorsia Pharmaceuticals Ltd | Crystalline form of (3s,7s,10r,13r)-13-benzyl-20-fluoro-7-isobutyl-n-(2-(3-methoxy-1,2,4-oxadiazol-5-yl)ethyl)-6,9-dimethyl-1,5,8,11-tetraoxo-10-(2,2,2-trifluoroethyl)-1,2,3,4,5,6,7,8,9,10,11,12,13,14-tetradecahydro-[1]oxa[4,7,10,14]tetraazacycloheptadecino[16,17-f]quinoline-3-carboxamide |
WO2024056798A1 (en) | 2022-09-15 | 2024-03-21 | Idorsia Pharmaceuticals Ltd | Macrocyclic cftr modulators |
Citations (4)
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CN1837351A (zh) * | 2006-04-12 | 2006-09-27 | 华东理工大学 | 高密度高品质培养小球藻的方法 |
CN101979498A (zh) * | 2010-12-01 | 2011-02-23 | 华东理工大学 | 一种微藻高产率异养培养的方法 |
CN102094061A (zh) * | 2010-12-01 | 2011-06-15 | 华东理工大学 | 一种利用微藻生产叶黄素的方法 |
CN102154110A (zh) * | 2011-01-27 | 2011-08-17 | 华东理工大学 | 一种高产率的微藻培养方法 |
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CN102021208A (zh) * | 2010-11-16 | 2011-04-20 | 华东理工大学 | 一种快速积累微藻胞内油脂的方法 |
-
2012
- 2012-07-27 CN CN201210264946.XA patent/CN103571906B/zh active Active
-
2013
- 2013-09-26 WO PCT/CN2013/084262 patent/WO2014015841A2/zh active Application Filing
- 2013-09-26 US US14/417,166 patent/US20150252391A1/en not_active Abandoned
- 2013-09-26 IN IN1606DEN2015 patent/IN2015DN01606A/en unknown
- 2013-09-26 EP EP13823422.4A patent/EP2878676A4/en not_active Withdrawn
- 2013-09-26 BR BR112015001637A patent/BR112015001637A2/pt not_active IP Right Cessation
- 2013-09-26 AU AU2013295436A patent/AU2013295436A1/en not_active Abandoned
Patent Citations (4)
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---|---|---|---|---|
CN1837351A (zh) * | 2006-04-12 | 2006-09-27 | 华东理工大学 | 高密度高品质培养小球藻的方法 |
CN101979498A (zh) * | 2010-12-01 | 2011-02-23 | 华东理工大学 | 一种微藻高产率异养培养的方法 |
CN102094061A (zh) * | 2010-12-01 | 2011-06-15 | 华东理工大学 | 一种利用微藻生产叶黄素的方法 |
CN102154110A (zh) * | 2011-01-27 | 2011-08-17 | 华东理工大学 | 一种高产率的微藻培养方法 |
Non-Patent Citations (3)
Title |
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HAN, CHUNMEI ET AL.: "Cell growth and astaxanthin accumulation of four strains of haematooccus pluvialis exposed to different plant regulators", OCEANOLOGIA ET LIMNOLOGIA SINICA, vol. 40, no. 4, July 2009 (2009-07-01), pages 430 - 436, XP008176479 * |
LIU, LONGYUN ET AL.: "Advances on the production of special natural carotenoids by microalgae", FOOD SCIENCE 0532-0968, vol. 30, no. 9, September 2006 (2006-09-01), pages 63 - 68, XP008176447 * |
ZHANG, D.H. ET AL.: "Two-step process for ketocarotenoid production by a green alga, Chlorococcum sp. Strain MA-1", APPL MICROBIOL BIOTECHNOL, vol. 55, no. 5, April 2001 (2001-04-01), pages 537 - 540, XP002689056 * |
Also Published As
Publication number | Publication date |
---|---|
CN103571906A (zh) | 2014-02-12 |
BR112015001637A2 (pt) | 2017-07-04 |
IN2015DN01606A (zh) | 2015-07-03 |
CN103571906B (zh) | 2018-12-11 |
AU2013295436A1 (en) | 2015-03-19 |
EP2878676A4 (en) | 2016-05-25 |
EP2878676A2 (en) | 2015-06-03 |
WO2014015841A2 (zh) | 2014-01-30 |
US20150252391A1 (en) | 2015-09-10 |
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