BR112015001637A2 - método usando microalgas para produção com eficiência elevada de astaxantina - Google Patents
método usando microalgas para produção com eficiência elevada de astaxantinaInfo
- Publication number
- BR112015001637A2 BR112015001637A2 BR112015001637A BR112015001637A BR112015001637A2 BR 112015001637 A2 BR112015001637 A2 BR 112015001637A2 BR 112015001637 A BR112015001637 A BR 112015001637A BR 112015001637 A BR112015001637 A BR 112015001637A BR 112015001637 A2 BR112015001637 A2 BR 112015001637A2
- Authority
- BR
- Brazil
- Prior art keywords
- astaxanthin
- microalgae
- production
- high efficiency
- culture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/12—Unicellular algae; Culture media therefor
Abstract
resumo da patente de invenção para: "método usando microalgas para produção com eficiência elevada de astaxantina". a presente invenção envolve um novo método usando microalgas para a produção com eficiência elevada de astaxantina, o método compreendendo etapas incluindo a cultura heterotrófica de microalgas, diluição, cultura induzida por luz, colheita de células de algas e a extração de astaxantina. o método da presente invenção tira proveito total do rápido crescimento de microalgas no estágio de cultura heterotrófica e do acúmulo elevado de astaxantina ocasionado pela cultura induzida por luz da grande quantidade de células de algas obtidas através da cultura heterotrófica para aumentar significativamente a eficiência de produção de astaxantina em microalgas e desse modo obter produção em baixo custo, eficiência elevada e grande escala de astaxantina através de microalgas. o método não somente fornece um meio técnico importante para tratar da produção industrial em grande escala de astaxantina, através de microalgas, como também assegura uma ampla fonte de matéria prima para a utilização difundida de astaxantina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210264946.XA CN103571906B (zh) | 2012-07-27 | 2012-07-27 | 一种利用微藻高效生产虾青素的新方法 |
| PCT/CN2013/084262 WO2014015841A2 (zh) | 2012-07-27 | 2013-09-26 | 一种利用微藻高效生产虾青素的新方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015001637A2 true BR112015001637A2 (pt) | 2017-07-04 |
Family
ID=49997905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015001637A BR112015001637A2 (pt) | 2012-07-27 | 2013-09-26 | método usando microalgas para produção com eficiência elevada de astaxantina |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20150252391A1 (pt) |
| EP (1) | EP2878676A4 (pt) |
| CN (1) | CN103571906B (pt) |
| AU (1) | AU2013295436A1 (pt) |
| BR (1) | BR112015001637A2 (pt) |
| IN (1) | IN2015DN01606A (pt) |
| WO (1) | WO2014015841A2 (pt) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101725976B1 (ko) * | 2014-04-17 | 2017-04-26 | 고려대학교 산학협력단 | 고온에서 성숙포자 접종 및 철이온매개 하버-바이스 반응에 의한 해마토코쿠스 플루비알리스 내 아스타잔틴 생산량 증진방법 |
| CN103966103A (zh) * | 2014-05-26 | 2014-08-06 | 临沂大学 | 利用啤酒厂废水培养雨生红球藻的培养基及培养方法 |
| CN104263649A (zh) * | 2014-09-15 | 2015-01-07 | 李健 | 一种大规模微藻培养的方法 |
| WO2016146803A1 (de) * | 2015-03-19 | 2016-09-22 | Basf Se | Astaxanthinzusammensetzungen (iii) |
| EP3270904B1 (de) * | 2015-03-19 | 2019-03-13 | Basf Se | Astaxanthinzusammensetzungen (i) |
| CN105420332A (zh) * | 2015-12-10 | 2016-03-23 | 天津科技大学 | 一种雨生红球藻高产虾青素的方法 |
| CN105462844B (zh) * | 2015-12-16 | 2019-05-03 | 中国科学院青岛生物能源与过程研究所 | 一种雨生红球藻细胞周期同步化的调控方法及其应用 |
| CN107189946B (zh) * | 2016-03-15 | 2022-07-01 | 嘉兴泽元生物制品有限责任公司 | 一种避免微藻光抑制以提高虾青素产量的方法 |
| EP3478850A1 (en) | 2016-06-30 | 2019-05-08 | Kuehnle Agrosystems, Inc. | Improved heterotrophic production methods for microbial biomass and bioproducts |
| CN106316847B (zh) * | 2016-08-16 | 2019-01-15 | 集美大学 | 一种虾青素亚油酸单酯的制备方法 |
| US20210010049A1 (en) * | 2016-09-21 | 2021-01-14 | Nippon Suisan Kaisha, Ltd. | Method for producing astaxanthin |
| CN106434817B (zh) * | 2016-09-29 | 2020-03-10 | 山东金晶生物技术有限公司 | 一种利用碱预处理技术提升雨生红球藻生产虾青素的方法 |
| EP3519555A1 (en) * | 2016-09-30 | 2019-08-07 | Heliae Development LLC | Methods of applying acetate toxicity and inducing acetate uptake in microalgae cultures |
| EP3812379A1 (en) | 2016-12-09 | 2021-04-28 | Vertex Pharmaceuticals Incorporated | Crystalline form of a n-(pyrazol-4-yl)sulfonyl-6-(pyrazol-1-yl)-2-(pyrrolidin-1-yl)pyridine-3-carboxamide for treating cystic fibrosis |
| US11253509B2 (en) | 2017-06-08 | 2022-02-22 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
| WO2019010092A1 (en) | 2017-07-01 | 2019-01-10 | Vertex Pharmaceuticals Incorporated | COMPOSITIONS AND METHODS FOR TREATING CYSTIC FIBROSIS |
| CN107384907A (zh) * | 2017-07-13 | 2017-11-24 | 荆楚理工学院 | 一种富硒虾青素小球藻粉的制备方法 |
| WO2019018353A1 (en) | 2017-07-17 | 2019-01-24 | Vertex Pharmaceuticals Incorporated | METHODS OF TREATING CYSTIC FIBROSIS |
| MA49631A (fr) | 2017-07-17 | 2020-05-27 | Vertex Pharma | Méthodes de traitement de la fibrose kystique |
| US10654829B2 (en) | 2017-10-19 | 2020-05-19 | Vertex Pharmaceuticals Incorporated | Crystalline forms and compositions of CFTR modulators |
| US20210228489A1 (en) | 2017-12-04 | 2021-07-29 | Vertex Pharmaceuticals Incorporated | Compositions for treating cystic fibrosis |
| TWI810243B (zh) | 2018-02-05 | 2023-08-01 | 美商維泰克斯製藥公司 | 用於治療囊腫纖化症之醫藥組合物 |
| US11066417B2 (en) | 2018-02-15 | 2021-07-20 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulators |
| US20210139514A1 (en) | 2018-04-05 | 2021-05-13 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| WO2019200246A1 (en) | 2018-04-13 | 2019-10-17 | Alexander Russell Abela | Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator |
| CN108504619B (zh) * | 2018-06-06 | 2021-06-01 | 中国科学院海洋研究所 | 一种缓解雨生红球藻光抑制的方法 |
| IT201800006555A1 (it) * | 2018-06-21 | 2019-12-21 | Procedimento per la coltivazione di alghe, preferibilmente di microalghe | |
| CN109566393A (zh) * | 2018-12-14 | 2019-04-05 | 浙江海洋大学 | 用于提取多糖的海藻的培养方法 |
| EP4036217A4 (en) * | 2019-09-23 | 2023-11-01 | Bioalgo (WF) Co., Ltd | METHOD FOR PRODUCING ASTAXANTHIN BY HETEROTROPHIC CULTURE OF HAEMATOCOCCUS PLUVIALIS |
| CN114286856A (zh) * | 2019-09-23 | 2022-04-05 | 山东拜昂生物技术有限公司 | 一种培养雨生红球藻生产虾青素的方法 |
| WO2022194399A1 (en) | 2020-07-13 | 2022-09-22 | Idorsia Pharmaceuticals Ltd | Macrocycles as cftr modulators |
| CN111979097A (zh) * | 2020-09-04 | 2020-11-24 | 清华大学 | 一种微藻培养用光生物反应器 |
| CN112239727B (zh) * | 2020-10-15 | 2022-04-01 | 大连理工大学 | 一种基于人工智能微藻混合系统培养微藻的方法 |
| KR102535358B1 (ko) * | 2021-03-30 | 2023-05-26 | 고려대학교 산학협력단 | 초음파 자극의 도입을 통한 미세조류 유래 고부가 가치 물질 생합성 증대법 |
| CN113717917A (zh) * | 2021-06-30 | 2021-11-30 | 中国海洋大学 | 一种雨生红球藻纯种培养的联合抗生素施用方法 |
| CN113817793A (zh) * | 2021-09-14 | 2021-12-21 | 国青(浙江)科学研究有限公司 | 一种叶黄素提高雨生红球藻中虾青素含量的生产工艺 |
| CN114214386A (zh) * | 2021-12-13 | 2022-03-22 | 广东百睿盈科生物科技有限公司 | 一种异养培养小球藻生产虾青素的方法 |
| CN114214202B (zh) * | 2021-12-27 | 2024-02-13 | 广西源藻生物科技有限公司 | 异养-光诱导串联培养微藻联产叶黄素和蛋白质的方法 |
| WO2024056798A1 (en) | 2022-09-15 | 2024-03-21 | Idorsia Pharmaceuticals Ltd | Macrocyclic cftr modulators |
| WO2024056779A1 (en) | 2022-09-15 | 2024-03-21 | Idorsia Pharmaceuticals Ltd | Crystalline form of (3s,7s,10r,13r)-13-benzyl-20-fluoro-7-isobutyl-n-(2-(3-methoxy-1,2,4-oxadiazol-5-yl)ethyl)-6,9-dimethyl-1,5,8,11-tetraoxo-10-(2,2,2-trifluoroethyl)-1,2,3,4,5,6,7,8,9,10,11,12,13,14-tetradecahydro-[1]oxa[4,7,10,14]tetraazacycloheptadecino[16,17-f]quinoline-3-carboxamide |
| WO2024056791A1 (en) | 2022-09-15 | 2024-03-21 | Idorsia Pharmaceuticals Ltd | Combination of macrocyclic cftr modulators with cftr correctors and / or cftr potentiators |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100410362C (zh) * | 2006-04-12 | 2008-08-13 | 华东理工大学 | 高密度高品质培养小球藻的方法 |
| CN102094061B (zh) * | 2010-12-01 | 2015-07-01 | 华东理工大学 | 一种利用微藻生产叶黄素的方法 |
| CN102021208A (zh) * | 2010-11-16 | 2011-04-20 | 华东理工大学 | 一种快速积累微藻胞内油脂的方法 |
| CN101979498B (zh) * | 2010-12-01 | 2016-05-04 | 华东理工大学 | 一种微藻高产率异养培养的方法 |
| CN102154110B (zh) * | 2011-01-27 | 2016-03-02 | 华东理工大学 | 一种高产率的微藻培养方法 |
-
2012
- 2012-07-27 CN CN201210264946.XA patent/CN103571906B/zh active Active
-
2013
- 2013-09-26 EP EP13823422.4A patent/EP2878676A4/en not_active Withdrawn
- 2013-09-26 AU AU2013295436A patent/AU2013295436A1/en not_active Abandoned
- 2013-09-26 US US14/417,166 patent/US20150252391A1/en not_active Abandoned
- 2013-09-26 IN IN1606DEN2015 patent/IN2015DN01606A/en unknown
- 2013-09-26 WO PCT/CN2013/084262 patent/WO2014015841A2/zh active Application Filing
- 2013-09-26 BR BR112015001637A patent/BR112015001637A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20150252391A1 (en) | 2015-09-10 |
| WO2014015841A2 (zh) | 2014-01-30 |
| IN2015DN01606A (pt) | 2015-07-03 |
| CN103571906B (zh) | 2018-12-11 |
| AU2013295436A1 (en) | 2015-03-19 |
| EP2878676A2 (en) | 2015-06-03 |
| EP2878676A4 (en) | 2016-05-25 |
| CN103571906A (zh) | 2014-02-12 |
| WO2014015841A3 (zh) | 2014-03-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112015001637A2 (pt) | método usando microalgas para produção com eficiência elevada de astaxantina | |
| CY1123146T1 (el) | Καλλιεργεια κυτταρου θηλαστικου | |
| AR069956A1 (es) | Procesos para cultivar celulas mamiferas secretoras de proteinas sanguineas heterologas | |
| BR112013025086A2 (pt) | sistema e métodos de biorreator multifuncional para classificação e cultura de células | |
| AR105435A2 (es) | Método de recombinación homóloga intramolecular en el genoma de una célula vegetal | |
| AR066239A1 (es) | Metodo para la produccion de proteinas mediante celulas cultivadas | |
| EA201390082A1 (ru) | Способ получения рекомбинантного adamts13 в культуре клеток | |
| AR094389A1 (es) | USO DE INHIBIDORES DE iNOS PARA AUMENTAR EL RENDIMIENTO VÍRICO EN CULTIVOS | |
| WO2012171030A3 (en) | Method and apparatus for antibody production and purification | |
| MY186219A (en) | Production of proteins in glutamine-free cell culture media | |
| EA201491785A1 (ru) | Способ ферментации | |
| AR116615A2 (es) | Operaciones de cosecha mejoradas para proteínas recombinadas | |
| BR112012030528A2 (pt) | processo e microrganismos para a produção de lipídios | |
| BR112016012371A2 (pt) | produção microbial de aminas graxas | |
| WO2011159709A3 (en) | Photobioreactor system | |
| BR112013032231A2 (pt) | planta de sorgo, pluralidade de sementes de sorgo, sementes de sorgo, método de produção das sementes, planta de sorgo doce, método de produção de cristais de sacarose, método de produção de uma planta, método de cultivo, processo para produção de biocombustível, uso de uma sequência de esterilidade, uso de uma planta, uso de uma planta de sorgo na produção de açúcar | |
| WO2010042484A3 (en) | Photobioreactor system with high specific growth rate and low dilution rate | |
| MX2015010887A (es) | Formulaciones y metodos para aumentar la produccion de proteinas recombinantes. | |
| MX353243B (es) | Metodo para incrementar la secrecion de proteinas recombinantes. | |
| MY183015A (en) | Solvent production using monophasic clostridia | |
| MX2021010889A (es) | Fotobiorreactor cronologico de pelicula delgada descendente. | |
| AR094308A1 (es) | Regeneracion de caña de azucar y metodos de transformacion | |
| MX2018011375A (es) | Microalgas geneticamente modificadas. | |
| UA105276C2 (ru) | Комплексный бактериальный препарат экофосфорин для обработки культурных растений | |
| BR112012019774B8 (pt) | método para produzir l-aminoácido |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |