IN2015DN01606A - - Google Patents

Info

Publication number
IN2015DN01606A
IN2015DN01606A IN1606DEN2015A IN2015DN01606A IN 2015DN01606 A IN2015DN01606 A IN 2015DN01606A IN 1606DEN2015 A IN1606DEN2015 A IN 1606DEN2015A IN 2015DN01606 A IN2015DN01606 A IN 2015DN01606A
Authority
IN
India
Prior art keywords
algae
astaxanthin
micro
production
efficiency
Prior art date
Application number
Inventor
Yuanguang Li
Zhen Zhang
Jianhua Fan
Minxi Wan
Dongmei Hou
Jingkui Zhang
Jianke Huang
Songtao Liang
Jun Wang
Jie Chen
Weiliang Wang
Shulan Li
Guomin Shen
Original Assignee
Univ East China Science & Tech
Jiaxing Zeyuan Bio Products Co Ltd
Shanghai Zeyuan Marine Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ East China Science & Tech, Jiaxing Zeyuan Bio Products Co Ltd, Shanghai Zeyuan Marine Biotechnology Co Ltd filed Critical Univ East China Science & Tech
Publication of IN2015DN01606A publication Critical patent/IN2015DN01606A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention involves a new method using micro -algae for the high-efficiency production of astaxanthin, said method comprising ste s including the heterotrophic culture of micro-algae, dilution, light-induced culture, harvesting of algae cells and the extraction of astaxanthin. The method of the present invention takes full advantage of the rapid growth of micro-algae in the heterotrophic culture stage and of the high accumulation of astaxanthin brought about by the light-induced culture of the great quantity of algae cells obtained through said heterotrophic culture to significantly increase the efficiency of production of astaxanthin in micro-algae and thereby achieve low-cost, high-efficiency and large scale production of astaxanthin through micro-algae. The method not only provides an important technical means t o address the large-scale industrial production of astaxanthin through micro -algae but also ensures an ample source of raw material for the widespread utilization of astaxanthin.
IN1606DEN2015 2012-07-27 2013-09-26 IN2015DN01606A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201210264946.XA CN103571906B (en) 2012-07-27 2012-07-27 A kind of new method efficiently producing astaxanthin using microalgae
PCT/CN2013/084262 WO2014015841A2 (en) 2012-07-27 2013-09-26 Method using micro-algae for high-efficiency production of astaxanthin

Publications (1)

Publication Number Publication Date
IN2015DN01606A true IN2015DN01606A (en) 2015-07-03

Family

ID=49997905

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1606DEN2015 IN2015DN01606A (en) 2012-07-27 2013-09-26

Country Status (7)

Country Link
US (1) US20150252391A1 (en)
EP (1) EP2878676A4 (en)
CN (1) CN103571906B (en)
AU (1) AU2013295436A1 (en)
BR (1) BR112015001637A2 (en)
IN (1) IN2015DN01606A (en)
WO (1) WO2014015841A2 (en)

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KR101725976B1 (en) * 2014-04-17 2017-04-26 고려대학교 산학협력단 Method for Increasing a Productivity of Astaxanthin in Haematococcus Pluvialis by Mature Cyst Inoculated and Iron Ions Mediated Haber-Weiss Reaction at High Temperature
CN103966103A (en) * 2014-05-26 2014-08-06 临沂大学 Culture medium and culture method for culturing haematococcus pluvialis by using brewery wastewater
CN104263649A (en) * 2014-09-15 2015-01-07 李健 Large-scale microalgae cultivation method
US20180110741A1 (en) * 2015-03-19 2018-04-26 Basf Se Astaxanthin compositions (i)
WO2016146803A1 (en) * 2015-03-19 2016-09-22 Basf Se Astaxanthin compositions (iii)
CN105420332A (en) * 2015-12-10 2016-03-23 天津科技大学 Method for achieving high yield of astaxanthin through haematococcus pluvialis
CN105462844B (en) * 2015-12-16 2019-05-03 中国科学院青岛生物能源与过程研究所 A kind of regulation method and its application of haematococcus pluvialis cell Cycle Synchronization
CN107189946B (en) * 2016-03-15 2022-07-01 嘉兴泽元生物制品有限责任公司 Method for improving astaxanthin yield by avoiding microalgae photoinhibition
CA3028227A1 (en) 2016-06-30 2018-01-04 Kuehnle Agrosystems, Inc. Improved heterotrophic production methods for microbial biomass and bioproducts
CN106316847B (en) * 2016-08-16 2019-01-15 集美大学 A kind of preparation method of astaxanthin linoleic acid monoesters
CN109642246A (en) * 2016-09-21 2019-04-16 日本水产株式会社 The production method of astaxanthin
CN106434817B (en) * 2016-09-29 2020-03-10 山东金晶生物技术有限公司 Method for improving haematococcus pluvialis production of astaxanthin by using alkali pretreatment technology
US20210284952A1 (en) * 2016-09-30 2021-09-16 Heliae Development Llc Methods of applying acetate toxicity and inducing acetate uptake in microalgae cultures
HUE052205T2 (en) 2016-12-09 2021-04-28 Vertex Pharma Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
US11253509B2 (en) 2017-06-08 2022-02-22 Vertex Pharmaceuticals Incorporated Methods of treatment for cystic fibrosis
WO2019010092A1 (en) 2017-07-01 2019-01-10 Vertex Pharmaceuticals Incorporated Compositions and methods for treatment of cystic fibrosis
CN107384907A (en) * 2017-07-13 2017-11-24 荆楚理工学院 A kind of preparation method of selenium-rich astaxanthin chlorella powder
WO2019018353A1 (en) 2017-07-17 2019-01-24 Vertex Pharmaceuticals Incorporated Methods of treatment for cystic fibrosis
BR112020000941A2 (en) 2017-07-17 2020-07-21 Vertex Pharmaceuticals Incorporated treatment methods for cystic fibrosis
WO2019079760A1 (en) 2017-10-19 2019-04-25 Vertex Pharmaceuticals Incorporated Crystalline forms and compositions of cftr modulators
WO2019113089A1 (en) 2017-12-04 2019-06-13 Vertex Pharmaceuticals Incorporated Compositions for treating cystic fibrosis
TWI810243B (en) 2018-02-05 2023-08-01 美商維泰克斯製藥公司 Pharmaceutical compositions for treating cystic fibrosis
MX2020008268A (en) 2018-02-15 2020-09-21 Vertex Pharma Macrocycles as modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions thereof, their use in the treatment of cycstic fibrosis, and process for making them.
WO2019195739A1 (en) 2018-04-05 2019-10-10 Alexander Russell Abela Modulators of cystic fibrosis transmembrane conductance regulator
US11414439B2 (en) 2018-04-13 2022-08-16 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
CN108504619B (en) * 2018-06-06 2021-06-01 中国科学院海洋研究所 Method for relieving light inhibition of haematococcus pluvialis
IT201800006555A1 (en) * 2018-06-21 2019-12-21 PROCEDURE FOR THE CULTIVATION OF ALGAE, PREFERABLY OF MICROALGAE
CN109566393A (en) * 2018-12-14 2019-04-05 浙江海洋大学 For extracting the cultural method of the seaweed of polysaccharide
CN114729297B (en) * 2019-09-23 2024-04-12 山东拜昂生物技术有限公司 Method for producing astaxanthin by heterotrophic culture of haematococcus pluvialis
WO2021057709A1 (en) * 2019-09-23 2021-04-01 山东拜昂生物技术有限公司 Method for culturing haematococcus pluvialis to produce astaxanthin
WO2022194399A1 (en) 2020-07-13 2022-09-22 Idorsia Pharmaceuticals Ltd Macrocycles as cftr modulators
CN111979097A (en) * 2020-09-04 2020-11-24 清华大学 Photobioreactor for microalgae culture
CN112239727B (en) * 2020-10-15 2022-04-01 大连理工大学 Method for culturing microalgae based on artificial intelligence microalgae mixing system
KR102535358B1 (en) * 2021-03-30 2023-05-26 고려대학교 산학협력단 Ultrasonic stimulation to increase the biosythesis of high value-added substances derived from microalgae
CN113717917A (en) * 2021-06-30 2021-11-30 中国海洋大学 Combined antibiotic application method for pure culture of haematococcus pluvialis
CN113817793A (en) * 2021-09-14 2021-12-21 国青(浙江)科学研究有限公司 Production process for increasing astaxanthin content in haematococcus pluvialis by lutein
CN114214386A (en) * 2021-12-13 2022-03-22 广东百睿盈科生物科技有限公司 Method for producing astaxanthin by heterotrophic culture of chlorella
CN114214202B (en) * 2021-12-27 2024-02-13 广西源藻生物科技有限公司 Method for co-producing lutein and protein by heterotrophic-photoinduction tandem culture of microalgae
WO2024056798A1 (en) 2022-09-15 2024-03-21 Idorsia Pharmaceuticals Ltd Macrocyclic cftr modulators
WO2024056791A1 (en) 2022-09-15 2024-03-21 Idorsia Pharmaceuticals Ltd Combination of macrocyclic cftr modulators with cftr correctors and / or cftr potentiators
WO2024056779A1 (en) 2022-09-15 2024-03-21 Idorsia Pharmaceuticals Ltd Crystalline form of (3s,7s,10r,13r)-13-benzyl-20-fluoro-7-isobutyl-n-(2-(3-methoxy-1,2,4-oxadiazol-5-yl)ethyl)-6,9-dimethyl-1,5,8,11-tetraoxo-10-(2,2,2-trifluoroethyl)-1,2,3,4,5,6,7,8,9,10,11,12,13,14-tetradecahydro-[1]oxa[4,7,10,14]tetraazacycloheptadecino[16,17-f]quinoline-3-carboxamide

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
CN100410362C (en) * 2006-04-12 2008-08-13 华东理工大学 Method for culturing chlorella with high-density and high-quality
CN102094061B (en) * 2010-12-01 2015-07-01 华东理工大学 Method for producing lutein from microalgae
CN102021208A (en) * 2010-11-16 2011-04-20 华东理工大学 Method for rapidly accumulating micro-algae intracellular grease
CN101979498B (en) * 2010-12-01 2016-05-04 华东理工大学 A kind of method that micro-algae high-yield heterotrophic is cultivated
CN102154110B (en) * 2011-01-27 2016-03-02 华东理工大学 A kind of microalgae culture method of high yield

Also Published As

Publication number Publication date
US20150252391A1 (en) 2015-09-10
WO2014015841A3 (en) 2014-03-20
CN103571906B (en) 2018-12-11
BR112015001637A2 (en) 2017-07-04
EP2878676A4 (en) 2016-05-25
EP2878676A2 (en) 2015-06-03
AU2013295436A1 (en) 2015-03-19
WO2014015841A2 (en) 2014-01-30
CN103571906A (en) 2014-02-12

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