IN160437B - - Google Patents

Info

Publication number
IN160437B
IN160437B IN1020/MAS/84A IN1020MA1984A IN160437B IN 160437 B IN160437 B IN 160437B IN 1020MA1984 A IN1020MA1984 A IN 1020MA1984A IN 160437 B IN160437 B IN 160437B
Authority
IN
India
Application number
IN1020/MAS/84A
Other languages
English (en)
Inventor
Francis Cooper Gary
Leslie Wren Douglas
Reynolds Van Horn Albert
Li Tsung-Tee
Charles Beard Colin
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Priority to IN1033/MAS/85A priority Critical patent/IN162770B/en
Publication of IN160437B publication Critical patent/IN160437B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IN1020/MAS/84A 1983-12-22 1984-12-20 IN160437B (ro)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IN1033/MAS/85A IN162770B (ro) 1983-12-22 1985-12-27

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/564,386 US4600785A (en) 1983-12-22 1983-12-22 Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives

Publications (1)

Publication Number Publication Date
IN160437B true IN160437B (ro) 1987-07-11

Family

ID=24254259

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1020/MAS/84A IN160437B (ro) 1983-12-22 1984-12-20

Country Status (28)

Country Link
US (1) US4600785A (ro)
EP (1) EP0146935B1 (ro)
JP (3) JPH0635431B2 (ro)
KR (1) KR900000684B1 (ro)
CN (1) CN85101840A (ro)
AR (1) AR241015A1 (ro)
AT (1) ATE50986T1 (ro)
AU (1) AU585844B2 (ro)
CA (4) CA1267892A (ro)
CS (5) CS600884A2 (ro)
DD (2) DD249700A5 (ro)
DE (1) DE3481610D1 (ro)
DK (1) DK617084A (ro)
ES (4) ES8604389A1 (ro)
FI (1) FI845069L (ro)
GR (1) GR82514B (ro)
HU (2) HU197302B (ro)
IL (1) IL73881A (ro)
IN (1) IN160437B (ro)
MX (2) MX158754A (ro)
NO (1) NO845148L (ro)
NZ (1) NZ210667A (ro)
PH (2) PH22893A (ro)
PL (2) PL154330B1 (ro)
PT (1) PT79720A (ro)
RO (2) RO91666B (ro)
SU (3) SU1473709A3 (ro)
ZA (1) ZA849967B (ro)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929740A (en) * 1984-10-09 1990-05-29 Syntex (U.S.A.) Inc. Process for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
CA1246560A (en) * 1984-10-09 1988-12-13 Gary F. Cooper Intermediates for making 16-phenoxy and 16- substituted phenoxy-prostatrienoic acid derivatives
US4778904A (en) * 1985-09-13 1988-10-18 Syntex (U.S.A.) Inc. Intermediates for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
US4755531A (en) * 1986-08-11 1988-07-05 Syntex (U.S.A.) Inc. Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents
US4689419A (en) * 1986-11-14 1987-08-25 G. D. Searle & Co. Novel intermediate compounds in a process for producing 16-phenoxy- and 16-substituted phenoxy-9-keto-prostatrienoic acid derivatives
US5248788A (en) * 1988-12-13 1993-09-28 Syntex (U.S.A.) Inc. Process for preparing allenic prostanoic acid derivatives
US4916238A (en) * 1988-12-13 1990-04-10 Syntex (U.S.A.) Inc. Process for preparing allenic prostanoic acid derivatives
US5571936A (en) * 1994-09-30 1996-11-05 Korea Institute Of Science And Technology Intermediates for the synthesis of 16-phenoxy-prostatrienoic acid derivatives and a preparing method thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304907A (en) * 1972-05-10 1981-12-08 The Upjohn Company Bicyclo lactone intermediates for prostaglandin analogs
JPS5434724B2 (ro) * 1974-09-19 1979-10-29
GB1590022A (en) * 1976-08-23 1981-05-28 Ono Pharmaceutical Co Prostaglandin analogues
US4178457A (en) * 1978-07-10 1979-12-11 Syntex (U.S.A.) Inc. (dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof
DE3030477C2 (de) * 1980-08-12 1986-10-16 Dr. Willmar Schwabe GmbH & Co, 7500 Karlsruhe Iridoid-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung
US4389414A (en) * 1981-05-11 1983-06-21 Syntex (U.S.A.) Inc. Prostaglandin compositions
EP0100052A1 (en) * 1982-07-19 1984-02-08 Syntex (U.S.A.) Inc. PGE type compositions encapsulated by acid isolated gelatin
HU196174B (en) * 1984-07-31 1988-10-28 Syntex Inc Process for preparing new prostaglandin derivatives and pharmaceutical compositions containing such active substance
US4618696A (en) * 1984-07-31 1986-10-21 Syntex (U.S.A.) Inc. 9-oxo-15α-hydroxy-16-phenoxy and 16-substituted phenoxy 17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates
CA1246560A (en) * 1984-10-09 1988-12-13 Gary F. Cooper Intermediates for making 16-phenoxy and 16- substituted phenoxy-prostatrienoic acid derivatives

Also Published As

Publication number Publication date
SU1342411A3 (ru) 1987-09-30
JPH0772170B2 (ja) 1995-08-02
AU585844B2 (en) 1989-06-29
KR850004589A (ko) 1985-07-25
CS257796B2 (en) 1988-06-15
ES8607229A1 (es) 1986-06-01
PL255723A1 (en) 1986-07-29
CS257784B2 (en) 1988-06-15
PH23728A (en) 1989-11-03
MX12599A (es) 1993-05-01
ES8609234A1 (es) 1986-08-01
DE3481610D1 (de) 1990-04-19
RO91666A (ro) 1987-07-30
CA1283408C (en) 1991-04-23
PL154330B1 (en) 1991-08-30
ES538899A0 (es) 1986-02-01
CS600784A2 (en) 1987-09-17
JPH0539262A (ja) 1993-02-19
ES548460A0 (es) 1986-06-01
SU1473709A3 (ru) 1989-04-15
RO91666B (ro) 1987-07-31
EP0146935B1 (en) 1990-03-14
SU1356959A3 (ru) 1987-11-30
EP0146935A3 (en) 1987-05-06
CA1267892A (en) 1990-04-17
JPH0635431B2 (ja) 1994-05-11
ES548459A0 (es) 1986-08-01
JPH0539263A (ja) 1993-02-19
ZA849967B (en) 1986-08-27
ATE50986T1 (de) 1990-03-15
CA1276931C (en) 1990-11-27
RO94561A7 (ro) 1988-06-30
PT79720A (en) 1985-01-01
FI845069A0 (fi) 1984-12-20
IL73881A0 (en) 1985-03-31
KR900000684B1 (ko) 1990-02-03
AR241015A1 (es) 1991-04-30
HU197302B (en) 1989-03-28
HU196732B (en) 1989-01-30
NO845148L (no) 1985-06-24
PL251088A1 (en) 1985-12-17
CS1013284A2 (en) 1987-09-17
US4600785A (en) 1986-07-15
IL73881A (en) 1990-01-18
AR241015A2 (es) 1991-04-30
ES8604389A1 (es) 1986-02-01
CS600884A2 (en) 1987-09-17
DK617084A (da) 1985-06-23
JPH0717597B2 (ja) 1995-03-01
PH22893A (en) 1989-01-19
CA1283409C (en) 1991-04-23
ES8607228A1 (es) 1986-06-01
MX158754A (es) 1989-03-10
JPS60169459A (ja) 1985-09-02
AU3712084A (en) 1985-07-04
DD249700A5 (de) 1987-09-16
HUT36090A (en) 1985-08-28
CN85101840A (zh) 1987-01-17
GR82514B (en) 1985-04-11
EP0146935A2 (en) 1985-07-03
DK617084D0 (da) 1984-12-20
FI845069L (fi) 1985-06-23
DD241254A5 (de) 1986-12-03
CS257797B2 (en) 1988-06-15
NZ210667A (en) 1988-08-30
ES548453A0 (es) 1986-06-01

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