DK617084A - Prostatriensyrederivater - Google Patents

Prostatriensyrederivater Download PDF

Info

Publication number
DK617084A
DK617084A DK617084A DK617084A DK617084A DK 617084 A DK617084 A DK 617084A DK 617084 A DK617084 A DK 617084A DK 617084 A DK617084 A DK 617084A DK 617084 A DK617084 A DK 617084A
Authority
DK
Denmark
Prior art keywords
prostatriic
acid derivatives
derivatives
acid
prostatriic acid
Prior art date
Application number
DK617084A
Other languages
English (en)
Other versions
DK617084D0 (da
Inventor
Gary Francis Cooper
Douglas Leslie Wren
Albert Reynolds Van Horn
Tsung-Tee Li
Colin Charles Beard
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK617084D0 publication Critical patent/DK617084D0/da
Publication of DK617084A publication Critical patent/DK617084A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK617084A 1983-12-22 1984-12-20 Prostatriensyrederivater DK617084A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/564,386 US4600785A (en) 1983-12-22 1983-12-22 Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives

Publications (2)

Publication Number Publication Date
DK617084D0 DK617084D0 (da) 1984-12-20
DK617084A true DK617084A (da) 1985-06-23

Family

ID=24254259

Family Applications (1)

Application Number Title Priority Date Filing Date
DK617084A DK617084A (da) 1983-12-22 1984-12-20 Prostatriensyrederivater

Country Status (28)

Country Link
US (1) US4600785A (da)
EP (1) EP0146935B1 (da)
JP (3) JPH0635431B2 (da)
KR (1) KR900000684B1 (da)
CN (1) CN85101840A (da)
AR (1) AR241015A1 (da)
AT (1) ATE50986T1 (da)
AU (1) AU585844B2 (da)
CA (4) CA1267892A (da)
CS (5) CS257784B2 (da)
DD (2) DD241254A5 (da)
DE (1) DE3481610D1 (da)
DK (1) DK617084A (da)
ES (4) ES8604389A1 (da)
FI (1) FI845069L (da)
GR (1) GR82514B (da)
HU (2) HU196732B (da)
IL (1) IL73881A (da)
IN (1) IN160437B (da)
MX (2) MX158754A (da)
NO (1) NO845148L (da)
NZ (1) NZ210667A (da)
PH (2) PH22893A (da)
PL (2) PL255723A1 (da)
PT (1) PT79720A (da)
RO (2) RO91666B (da)
SU (3) SU1473709A3 (da)
ZA (1) ZA849967B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4778904A (en) * 1985-09-13 1988-10-18 Syntex (U.S.A.) Inc. Intermediates for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
US4929740A (en) * 1984-10-09 1990-05-29 Syntex (U.S.A.) Inc. Process for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
NZ213749A (en) * 1984-10-09 1989-01-06 Syntex Inc Ethers for use as intermediates in the preparation of 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4755531A (en) * 1986-08-11 1988-07-05 Syntex (U.S.A.) Inc. Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents
US4689419A (en) * 1986-11-14 1987-08-25 G. D. Searle & Co. Novel intermediate compounds in a process for producing 16-phenoxy- and 16-substituted phenoxy-9-keto-prostatrienoic acid derivatives
US4916238A (en) * 1988-12-13 1990-04-10 Syntex (U.S.A.) Inc. Process for preparing allenic prostanoic acid derivatives
US5248788A (en) * 1988-12-13 1993-09-28 Syntex (U.S.A.) Inc. Process for preparing allenic prostanoic acid derivatives
US5571936A (en) * 1994-09-30 1996-11-05 Korea Institute Of Science And Technology Intermediates for the synthesis of 16-phenoxy-prostatrienoic acid derivatives and a preparing method thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304907A (en) * 1972-05-10 1981-12-08 The Upjohn Company Bicyclo lactone intermediates for prostaglandin analogs
JPS5434724B2 (da) * 1974-09-19 1979-10-29
GB1590022A (en) * 1976-08-23 1981-05-28 Ono Pharmaceutical Co Prostaglandin analogues
US4178457A (en) * 1978-07-10 1979-12-11 Syntex (U.S.A.) Inc. (dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof
DE3030477C2 (de) * 1980-08-12 1986-10-16 Dr. Willmar Schwabe GmbH & Co, 7500 Karlsruhe Iridoid-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung
US4389414A (en) * 1981-05-11 1983-06-21 Syntex (U.S.A.) Inc. Prostaglandin compositions
AU1695783A (en) * 1982-07-19 1984-01-26 Syntex (U.S.A.) Inc. Encapsulated pge type compositions
EP0170258B1 (en) * 1984-07-31 1989-12-27 Syntex (U.S.A.) Inc. 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4618696A (en) * 1984-07-31 1986-10-21 Syntex (U.S.A.) Inc. 9-oxo-15α-hydroxy-16-phenoxy and 16-substituted phenoxy 17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates
NZ213749A (en) * 1984-10-09 1989-01-06 Syntex Inc Ethers for use as intermediates in the preparation of 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives

Also Published As

Publication number Publication date
CN85101840A (zh) 1987-01-17
HU197302B (en) 1989-03-28
AR241015A1 (es) 1991-04-30
DE3481610D1 (de) 1990-04-19
HUT36090A (en) 1985-08-28
EP0146935A2 (en) 1985-07-03
DD241254A5 (de) 1986-12-03
CA1267892A (en) 1990-04-17
HU196732B (en) 1989-01-30
FI845069L (fi) 1985-06-23
ES548460A0 (es) 1986-06-01
ATE50986T1 (de) 1990-03-15
JPH0539262A (ja) 1993-02-19
ES538899A0 (es) 1986-02-01
PL251088A1 (en) 1985-12-17
CS257796B2 (en) 1988-06-15
IN160437B (da) 1987-07-11
PH22893A (en) 1989-01-19
ES8607228A1 (es) 1986-06-01
EP0146935A3 (en) 1987-05-06
ES548453A0 (es) 1986-06-01
CA1276931C (en) 1990-11-27
JPH0772170B2 (ja) 1995-08-02
PT79720A (en) 1985-01-01
NZ210667A (en) 1988-08-30
IL73881A (en) 1990-01-18
PL154330B1 (en) 1991-08-30
CS600884A2 (en) 1987-09-17
ES8609234A1 (es) 1986-08-01
AU3712084A (en) 1985-07-04
JPH0717597B2 (ja) 1995-03-01
ES8607229A1 (es) 1986-06-01
DD249700A5 (de) 1987-09-16
AR241015A2 (es) 1991-04-30
AU585844B2 (en) 1989-06-29
CA1283409C (en) 1991-04-23
CS257784B2 (en) 1988-06-15
CS600784A2 (en) 1987-09-17
NO845148L (no) 1985-06-24
ES8604389A1 (es) 1986-02-01
PH23728A (en) 1989-11-03
JPS60169459A (ja) 1985-09-02
US4600785A (en) 1986-07-15
JPH0539263A (ja) 1993-02-19
FI845069A0 (fi) 1984-12-20
ZA849967B (en) 1986-08-27
RO91666B (ro) 1987-07-31
PL255723A1 (en) 1986-07-29
EP0146935B1 (en) 1990-03-14
MX158754A (es) 1989-03-10
KR900000684B1 (ko) 1990-02-03
GR82514B (en) 1985-04-11
MX12599A (es) 1993-05-01
JPH0635431B2 (ja) 1994-05-11
CS1013284A2 (en) 1987-09-17
ES548459A0 (es) 1986-08-01
RO94561A7 (ro) 1988-06-30
IL73881A0 (en) 1985-03-31
RO91666A (ro) 1987-07-30
CS257797B2 (en) 1988-06-15
DK617084D0 (da) 1984-12-20
CA1283408C (en) 1991-04-23
SU1473709A3 (ru) 1989-04-15
SU1342411A3 (ru) 1987-09-30
KR850004589A (ko) 1985-07-25
SU1356959A3 (ru) 1987-11-30

Similar Documents

Publication Publication Date Title
DE3368052D1 (de) 4-chloro-2-phenylimidazole-5-acetic acid derivatives
DK158092D0 (da) Phenthanolaminderivater
DK159384D0 (da) Ergocalciferolderivater
DK35384A (da) Vinylcephalosporin-derivater
DK221384D0 (da) Isoindolderivater
DK20884A (da) Phenothiazonderivater
ATE34383T1 (de) Oxamidsaeure-derivate.
DE3464610D1 (de) 2-alkylthiopenem derivatives
DK272083D0 (da) Oxazoleddikesyrederivater
DE3483294D1 (de) Barbitursaeurederivate.
DK522984A (da) Pyrazolopyridincykloalkanon-derivater
DK354684A (da) Azol-dioxolan-derivater
DK617084D0 (da) Prostatriensyrederivater
DE3360053D1 (de) 3-benzoyl-2-mercaptopropionic acid derivatives
DK340485A (da) Phenylnonatetraensyrederivater
DK346984A (da) Formamidoximderivater
DE3477197D1 (de) 2-azacycloalkylthiopenem derivatives
DK317985A (da) Aminoeburnancarboxylsyrederivater
DE3467164D1 (de) Pyrrole-2-acetylamino acid derivatives
DK318085D0 (da) Nitroapovincaminsyrederivater
DE3472258D1 (de) Thiodeazapurine derivatives
DE3476803D1 (de) Furane-3-carboxylic-acid derivatives
DK536184D0 (da) Pyrimidoisoquinolinderivater
DK149271C (da) Beta-carbolin-3-carboxylsyrederivater
DE3473268D1 (de) 5-fluorouracilnitroxylderivatives

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment