ES548460A0 - Procedimiento para preparar derivados de acidos 16-fenoxi y 16-(fenoxi sustituido)-prostatrienoicos y sus estereoisome- ros - Google Patents
Procedimiento para preparar derivados de acidos 16-fenoxi y 16-(fenoxi sustituido)-prostatrienoicos y sus estereoisome- rosInfo
- Publication number
- ES548460A0 ES548460A0 ES548460A ES548460A ES548460A0 ES 548460 A0 ES548460 A0 ES 548460A0 ES 548460 A ES548460 A ES 548460A ES 548460 A ES548460 A ES 548460A ES 548460 A0 ES548460 A0 ES 548460A0
- Authority
- ES
- Spain
- Prior art keywords
- prostatrienoics
- stereoisomes
- phenoxi
- ros
- phenoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/564,386 US4600785A (en) | 1983-12-22 | 1983-12-22 | Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8607229A1 ES8607229A1 (es) | 1986-06-01 |
| ES548460A0 true ES548460A0 (es) | 1986-06-01 |
Family
ID=24254259
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES538899A Expired ES8604389A1 (es) | 1983-12-22 | 1984-12-20 | Procedimientos y compuestos intermedios para preparar derivados de acidos 16-(fenoxi substituido)-prostatrinoicos y sus sales esteroisomeros |
| ES548453A Expired ES8607228A1 (es) | 1983-12-22 | 1985-10-31 | Procedimiento para preparar derivados de acidos 16-fenoxi y 16(fenoxi sustituido)-prostatrienoicos y sus estereoisomeros |
| ES548459A Expired ES8609234A1 (es) | 1983-12-22 | 1985-10-31 | Procedimiento para preparar (4,5,6r,8r)-9-oxo-11,15 dihidro-xi-16-fenoxi-17,18,19,20-tetranorprosta-4,5,13 (e) trienoatometilico cristalino |
| ES548460A Expired ES8607229A1 (es) | 1983-12-22 | 1985-10-31 | Procedimiento para preparar derivados de acidos 16-fenoxi y 16-(fenoxi sustituido)-prostatrienoicos y sus estereoisome- ros |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES538899A Expired ES8604389A1 (es) | 1983-12-22 | 1984-12-20 | Procedimientos y compuestos intermedios para preparar derivados de acidos 16-(fenoxi substituido)-prostatrinoicos y sus sales esteroisomeros |
| ES548453A Expired ES8607228A1 (es) | 1983-12-22 | 1985-10-31 | Procedimiento para preparar derivados de acidos 16-fenoxi y 16(fenoxi sustituido)-prostatrienoicos y sus estereoisomeros |
| ES548459A Expired ES8609234A1 (es) | 1983-12-22 | 1985-10-31 | Procedimiento para preparar (4,5,6r,8r)-9-oxo-11,15 dihidro-xi-16-fenoxi-17,18,19,20-tetranorprosta-4,5,13 (e) trienoatometilico cristalino |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4600785A (es) |
| EP (1) | EP0146935B1 (es) |
| JP (3) | JPH0635431B2 (es) |
| KR (1) | KR900000684B1 (es) |
| CN (1) | CN85101840A (es) |
| AR (1) | AR241015A1 (es) |
| AT (1) | ATE50986T1 (es) |
| AU (1) | AU585844B2 (es) |
| CA (4) | CA1267892A (es) |
| CS (5) | CS257784B2 (es) |
| DD (2) | DD241254A5 (es) |
| DE (1) | DE3481610D1 (es) |
| DK (1) | DK617084A (es) |
| ES (4) | ES8604389A1 (es) |
| FI (1) | FI845069L (es) |
| GR (1) | GR82514B (es) |
| HU (2) | HU197302B (es) |
| IL (1) | IL73881A (es) |
| IN (1) | IN160437B (es) |
| MX (2) | MX158754A (es) |
| NO (1) | NO845148L (es) |
| NZ (1) | NZ210667A (es) |
| PH (2) | PH22893A (es) |
| PL (2) | PL255723A1 (es) |
| PT (1) | PT79720A (es) |
| RO (2) | RO91666B (es) |
| SU (3) | SU1473709A3 (es) |
| ZA (1) | ZA849967B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4929740A (en) * | 1984-10-09 | 1990-05-29 | Syntex (U.S.A.) Inc. | Process for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives |
| HU197290B (en) * | 1984-10-09 | 1989-03-28 | Syntex Inc | Process for preparing intermediate products for the production of 16-phenoxy- and 16-(substituted phenoxy)-prostatriene acid-derivatives |
| US4778904A (en) * | 1985-09-13 | 1988-10-18 | Syntex (U.S.A.) Inc. | Intermediates for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives |
| US4755531A (en) * | 1986-08-11 | 1988-07-05 | Syntex (U.S.A.) Inc. | Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents |
| US4689419A (en) * | 1986-11-14 | 1987-08-25 | G. D. Searle & Co. | Novel intermediate compounds in a process for producing 16-phenoxy- and 16-substituted phenoxy-9-keto-prostatrienoic acid derivatives |
| US4916238A (en) * | 1988-12-13 | 1990-04-10 | Syntex (U.S.A.) Inc. | Process for preparing allenic prostanoic acid derivatives |
| US5248788A (en) * | 1988-12-13 | 1993-09-28 | Syntex (U.S.A.) Inc. | Process for preparing allenic prostanoic acid derivatives |
| US5571936A (en) * | 1994-09-30 | 1996-11-05 | Korea Institute Of Science And Technology | Intermediates for the synthesis of 16-phenoxy-prostatrienoic acid derivatives and a preparing method thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4304907A (en) * | 1972-05-10 | 1981-12-08 | The Upjohn Company | Bicyclo lactone intermediates for prostaglandin analogs |
| JPS5434724B2 (es) * | 1974-09-19 | 1979-10-29 | ||
| GB1590022A (en) * | 1976-08-23 | 1981-05-28 | Ono Pharmaceutical Co | Prostaglandin analogues |
| US4178457A (en) * | 1978-07-10 | 1979-12-11 | Syntex (U.S.A.) Inc. | (dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof |
| DE3030477C2 (de) * | 1980-08-12 | 1986-10-16 | Dr. Willmar Schwabe GmbH & Co, 7500 Karlsruhe | Iridoid-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung |
| US4389414A (en) * | 1981-05-11 | 1983-06-21 | Syntex (U.S.A.) Inc. | Prostaglandin compositions |
| CA1216793A (en) * | 1982-07-19 | 1987-01-20 | Cheng-Der Yu | Pge-type compositions encapsulated by acid isolated gelatin |
| ZA855740B (en) * | 1984-07-31 | 1987-03-25 | Syntex Inc | 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives |
| US4618696A (en) * | 1984-07-31 | 1986-10-21 | Syntex (U.S.A.) Inc. | 9-oxo-15α-hydroxy-16-phenoxy and 16-substituted phenoxy 17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates |
| HU197290B (en) * | 1984-10-09 | 1989-03-28 | Syntex Inc | Process for preparing intermediate products for the production of 16-phenoxy- and 16-(substituted phenoxy)-prostatriene acid-derivatives |
-
1983
- 1983-12-22 US US06/564,386 patent/US4600785A/en not_active Expired - Fee Related
-
1984
- 1984-12-19 GR GR82514A patent/GR82514B/el unknown
- 1984-12-20 JP JP59270571A patent/JPH0635431B2/ja not_active Expired - Lifetime
- 1984-12-20 CA CA000470699A patent/CA1267892A/en not_active Expired - Fee Related
- 1984-12-20 DE DE8484115950T patent/DE3481610D1/de not_active Expired - Fee Related
- 1984-12-20 PL PL25572384A patent/PL255723A1/xx unknown
- 1984-12-20 IL IL73881A patent/IL73881A/xx unknown
- 1984-12-20 NZ NZ210667A patent/NZ210667A/xx unknown
- 1984-12-20 AR AR299047A patent/AR241015A1/es active
- 1984-12-20 IN IN1020/MAS/84A patent/IN160437B/en unknown
- 1984-12-20 DD DD84271309A patent/DD241254A5/de not_active IP Right Cessation
- 1984-12-20 FI FI845069A patent/FI845069L/fi not_active Application Discontinuation
- 1984-12-20 AU AU37120/84A patent/AU585844B2/en not_active Ceased
- 1984-12-20 SU SU843828202A patent/SU1473709A3/ru active
- 1984-12-20 PT PT79720A patent/PT79720A/pt unknown
- 1984-12-20 ZA ZA849967A patent/ZA849967B/xx unknown
- 1984-12-20 HU HU844754A patent/HU197302B/hu not_active IP Right Cessation
- 1984-12-20 RO RO116780A patent/RO91666B/ro unknown
- 1984-12-20 KR KR1019840008147A patent/KR900000684B1/ko not_active IP Right Cessation
- 1984-12-20 CS CS8410132A patent/CS257784B2/cs unknown
- 1984-12-20 NO NO845148A patent/NO845148L/no unknown
- 1984-12-20 CS CS866007A patent/CS600784A2/cs unknown
- 1984-12-20 MX MX203853A patent/MX158754A/es unknown
- 1984-12-20 DD DD84294680A patent/DD249700A5/de unknown
- 1984-12-20 AT AT84115950T patent/ATE50986T1/de not_active IP Right Cessation
- 1984-12-20 PH PH31623A patent/PH22893A/en unknown
- 1984-12-20 CS CS866008A patent/CS600884A2/cs unknown
- 1984-12-20 ES ES538899A patent/ES8604389A1/es not_active Expired
- 1984-12-20 DK DK617084A patent/DK617084A/da not_active Application Discontinuation
- 1984-12-20 PL PL1984251088A patent/PL154330B1/pl unknown
- 1984-12-20 RO RO84124019A patent/RO94561A7/ro unknown
- 1984-12-20 HU HU863355A patent/HU196732B/hu not_active IP Right Cessation
- 1984-12-20 EP EP84115950A patent/EP0146935B1/en not_active Expired - Lifetime
-
1985
- 1985-04-01 CN CN198585101840A patent/CN85101840A/zh active Pending
- 1985-09-24 SU SU853955491A patent/SU1356959A3/ru active
- 1985-09-24 SU SU853955489A patent/SU1342411A3/ru active
- 1985-10-31 ES ES548453A patent/ES8607228A1/es not_active Expired
- 1985-10-31 ES ES548459A patent/ES8609234A1/es not_active Expired
- 1985-10-31 ES ES548460A patent/ES8607229A1/es not_active Expired
-
1986
- 1986-05-09 PH PH33751A patent/PH23728A/en unknown
- 1986-08-14 CS CS866008A patent/CS257797B2/cs unknown
- 1986-08-14 CS CS866007A patent/CS257796B2/cs unknown
-
1988
- 1988-08-09 MX MX1259988A patent/MX12599A/es unknown
- 1988-08-11 CA CA000574537A patent/CA1276931C/en not_active Expired - Fee Related
- 1988-08-11 CA CA000574538A patent/CA1283408C/en not_active Expired - Fee Related
- 1988-08-12 CA CA000574703A patent/CA1283409C/en not_active Expired - Fee Related
-
1991
- 1991-12-19 JP JP3336862A patent/JPH0717597B2/ja not_active Expired - Lifetime
- 1991-12-19 JP JP3336857A patent/JPH0772170B2/ja not_active Expired - Lifetime
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