IL98862A0 - Process for the preparation of biphenylcarbonitrile derivatives - Google Patents
Process for the preparation of biphenylcarbonitrile derivativesInfo
- Publication number
- IL98862A0 IL98862A0 IL98862A IL9886291A IL98862A0 IL 98862 A0 IL98862 A0 IL 98862A0 IL 98862 A IL98862 A IL 98862A IL 9886291 A IL9886291 A IL 9886291A IL 98862 A0 IL98862 A0 IL 98862A0
- Authority
- IL
- Israel
- Prior art keywords
- novel
- derivatives
- certain
- defined hereinafter
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/50—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Turning (AREA)
- Glass Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Electrotherapy Devices (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Air Bags (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909017482A GB9017482D0 (en) | 1990-08-09 | 1990-08-09 | Manufacturing process |
Publications (1)
Publication Number | Publication Date |
---|---|
IL98862A0 true IL98862A0 (en) | 1992-07-15 |
Family
ID=10680408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL98862A IL98862A0 (en) | 1990-08-09 | 1991-07-16 | Process for the preparation of biphenylcarbonitrile derivatives |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP0470795B2 (es) |
JP (1) | JP3001298B2 (es) |
KR (1) | KR920004337A (es) |
CN (1) | CN1059516A (es) |
AT (1) | ATE117672T1 (es) |
AU (1) | AU646473B2 (es) |
CA (1) | CA2047369A1 (es) |
CS (1) | CS241391A3 (es) |
DE (1) | DE69106977T3 (es) |
ES (1) | ES2067159T3 (es) |
FI (1) | FI913640A (es) |
GB (2) | GB9017482D0 (es) |
HU (1) | HU207841B (es) |
IL (1) | IL98862A0 (es) |
NO (1) | NO174502B (es) |
NZ (1) | NZ239026A (es) |
PL (1) | PL291370A1 (es) |
PT (1) | PT98608A (es) |
RU (1) | RU2026285C1 (es) |
TW (1) | TW198710B (es) |
YU (1) | YU137891A (es) |
ZA (1) | ZA915566B (es) |
ZW (1) | ZW9591A1 (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU155290A (sh) * | 1989-08-11 | 1993-05-28 | Imperial Chemical Industries Plc. | Dusikove spojine |
DE4132633A1 (de) * | 1991-10-01 | 1993-04-08 | Bayer Ag | Cyclisch substituierte imidazolyl-propensaeurederivate |
DE4132632A1 (de) * | 1991-10-01 | 1993-04-08 | Bayer Ag | Substituierte imidazolyl-propensaeurederivate |
DE4132631A1 (de) * | 1991-10-01 | 1993-04-08 | Bayer Ag | Imidazolyl-propensaeurederivate |
US5206374A (en) * | 1991-11-18 | 1993-04-27 | E. I. Du Pont De Nemours And Company | Process for preparing tetrazolylphenylboronic acid intermediates |
US5310928A (en) * | 1991-11-18 | 1994-05-10 | E. I. Du Pont De Nemours And Company | Process for preparing biphenyltetrazole compounds |
FR2688507B1 (fr) * | 1992-03-16 | 1994-05-06 | Synthelabo | Derives de l'acide tetrazolylbenzeneboronique, leur preparation et leur utilisation comme intermediaires de synthese. |
FR2689887B1 (fr) * | 1992-04-13 | 1995-06-23 | Sanofi Elf | Procede de preparation d'un derive de biphenyle. |
FR2696746B1 (fr) * | 1992-10-12 | 1994-11-18 | Synthelabo | Dérivés de l'acide benzèneborinique, leur préparation et leur utilisation comme intermédiaires de synthèse. |
DE4423061C1 (de) | 1994-07-01 | 1996-01-18 | Hoechst Ag | Verfahren zur Herstellung von Biphenylen mit Palladacyclen als Katalysatoren |
DE4426671A1 (de) * | 1994-07-28 | 1996-02-01 | Hoechst Ag | Verfahren zur Kreuzkupplung von aromatischen Borverbindungen mit aromatischen Halogenverbindungen oder Perfluoralkylsulfonaten |
KR100354802B1 (ko) * | 1994-10-20 | 2002-12-26 | 한국화학연구원 | 테트라졸유도체의제조방법 |
JP2928982B2 (ja) | 1994-10-27 | 1999-08-03 | 住化ファインケム株式会社 | 4’−ブロモメチル−2−シアノビフェニルの製造法 |
DE19620023C2 (de) * | 1996-05-17 | 2001-03-08 | Celanese Chem Europe Gmbh | Verfahren zur Herstellung von Phosphinat- oder Phosphonatgruppen enthaltenden tertiären Phosphanen und neue Phosphinatgruppen enthaltende tertiäre Phosphane |
US6194599B1 (en) | 1997-04-08 | 2001-02-27 | Catalytica, Inc. | Process for preparing biaryl compounds |
US5922898A (en) * | 1997-04-08 | 1999-07-13 | Catalytica Pharmaceuticals, Inc. | Process for preparing biaryl compounds |
EP1064243B1 (en) | 1998-03-18 | 2002-10-23 | Ciba SC Holding AG | Coupling reactions with palladium catalysts |
US6962999B2 (en) | 2001-07-25 | 2005-11-08 | Pharmacore, Inc. | Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles |
DE10211597A1 (de) * | 2002-03-15 | 2003-10-02 | Merck Patent Gmbh | Verfahren zur Herstellung von Ringverbindungen |
AU2003228767A1 (en) | 2002-04-29 | 2003-11-17 | Teva Pharmaceutical Industries Ltd. | Processes for preparing losartan and losartan potassium |
ATE388136T1 (de) | 2002-06-12 | 2008-03-15 | Sumitomo Chemical Co | Verfahren zur herstellung von 4'-brommethyl-2- cyanobiphenyl |
US7105467B2 (en) | 2003-07-08 | 2006-09-12 | Pharmacore, Inc. | Nickel catalyzed cross-coupling reactions between organomagnesium compounds and anisole derivatives |
US7105707B2 (en) | 2003-12-17 | 2006-09-12 | Pharmacore, Inc. | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds |
JP2006151946A (ja) * | 2004-04-30 | 2006-06-15 | Konishi Kagaku Ind Co Ltd | ジアリール誘導体の製造方法 |
MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
EP3241839B1 (en) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
CN102482195B (zh) * | 2009-08-31 | 2015-04-01 | 拜尔农作物科学股份公司 | 制备取代联苯的四芳基硼酸盐法 |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
EA201592263A1 (ru) | 2013-06-05 | 2016-05-31 | Синерджи Фармасьютикалз, Инк. | Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования |
JP5975081B2 (ja) * | 2013-09-30 | 2016-08-23 | ダイキン工業株式会社 | 含フッ素ビアリール化合物の製造方法 |
KR101512729B1 (ko) | 2014-01-17 | 2015-04-17 | 에프케이엔지니어링 주식회사 | 화장로 |
IL312547A (en) | 2021-11-02 | 2024-07-01 | Flare Therapeutics Inc | PPARG inverse agonists and uses thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
JP2633338B2 (ja) * | 1987-10-19 | 1997-07-23 | イギリス国 | 側方がシアノ―置換されているテルフェニル |
CA1338238C (en) * | 1988-01-07 | 1996-04-09 | David John Carini | Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids |
YU155290A (sh) * | 1989-08-11 | 1993-05-28 | Imperial Chemical Industries Plc. | Dusikove spojine |
-
1990
- 1990-08-09 GB GB909017482A patent/GB9017482D0/en active Pending
-
1991
- 1991-07-15 ZW ZW95/91A patent/ZW9591A1/xx unknown
- 1991-07-16 IL IL98862A patent/IL98862A0/xx unknown
- 1991-07-16 AU AU80436/91A patent/AU646473B2/en not_active Ceased
- 1991-07-16 ZA ZA915566A patent/ZA915566B/xx unknown
- 1991-07-16 GB GB919115244A patent/GB9115244D0/en active Pending
- 1991-07-18 NZ NZ239026A patent/NZ239026A/en unknown
- 1991-07-18 CA CA002047369A patent/CA2047369A1/en not_active Abandoned
- 1991-07-24 HU HU912481A patent/HU207841B/hu not_active IP Right Cessation
- 1991-07-29 CN CN91105206A patent/CN1059516A/zh active Pending
- 1991-07-30 FI FI913640A patent/FI913640A/fi unknown
- 1991-08-02 CS CS912413A patent/CS241391A3/cs unknown
- 1991-08-05 ES ES91307184T patent/ES2067159T3/es not_active Expired - Lifetime
- 1991-08-05 EP EP91307184A patent/EP0470795B2/en not_active Expired - Lifetime
- 1991-08-05 AT AT91307184T patent/ATE117672T1/de active
- 1991-08-05 DE DE69106977T patent/DE69106977T3/de not_active Expired - Fee Related
- 1991-08-08 PT PT98608A patent/PT98608A/pt not_active Application Discontinuation
- 1991-08-08 NO NO913086A patent/NO174502B/no unknown
- 1991-08-08 KR KR1019910013873A patent/KR920004337A/ko not_active Application Discontinuation
- 1991-08-08 PL PL29137091A patent/PL291370A1/xx unknown
- 1991-08-08 RU SU915001352A patent/RU2026285C1/ru active
- 1991-08-08 JP JP3199442A patent/JP3001298B2/ja not_active Expired - Fee Related
- 1991-08-09 YU YU137891A patent/YU137891A/sh unknown
- 1991-08-12 TW TW080106352A patent/TW198710B/zh active
Also Published As
Publication number | Publication date |
---|---|
ZA915566B (en) | 1992-04-29 |
NO913086D0 (no) | 1991-08-08 |
GB9017482D0 (en) | 1990-09-26 |
HUT59662A (en) | 1992-06-29 |
CS241391A3 (en) | 1992-03-18 |
CN1059516A (zh) | 1992-03-18 |
NO174502B (no) | 1994-02-07 |
AU8043691A (en) | 1992-02-13 |
HU912481D0 (en) | 1991-12-30 |
ZW9591A1 (en) | 1992-06-10 |
KR920004337A (ko) | 1992-03-27 |
ES2067159T3 (es) | 1995-03-16 |
DE69106977T2 (de) | 1995-05-24 |
YU137891A (sh) | 1994-06-10 |
DE69106977D1 (de) | 1995-03-09 |
NO913086L (no) | 1992-02-10 |
NO174502C (es) | 1994-05-18 |
FI913640A0 (fi) | 1991-07-30 |
EP0470795B2 (en) | 2001-02-21 |
AU646473B2 (en) | 1994-02-24 |
TW198710B (es) | 1993-01-21 |
DE69106977T3 (de) | 2001-07-19 |
JPH04253949A (ja) | 1992-09-09 |
EP0470795B1 (en) | 1995-01-25 |
PL291370A1 (en) | 1992-11-16 |
JP3001298B2 (ja) | 2000-01-24 |
GB9115244D0 (en) | 1991-08-28 |
HU207841B (en) | 1993-06-28 |
RU2026285C1 (ru) | 1995-01-09 |
FI913640A (fi) | 1992-02-10 |
PT98608A (pt) | 1992-06-30 |
EP0470795A1 (en) | 1992-02-12 |
NZ239026A (en) | 1993-12-23 |
ATE117672T1 (de) | 1995-02-15 |
CA2047369A1 (en) | 1992-02-10 |
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