DK0503453T3 - Fremgangsmåde til fremstilling af cephalosporiner og mellemprodukter i denne fremgangsmåde - Google Patents

Fremgangsmåde til fremstilling af cephalosporiner og mellemprodukter i denne fremgangsmåde

Info

Publication number
DK0503453T3
DK0503453T3 DK92103666T DK92103666T DK0503453T3 DK 0503453 T3 DK0503453 T3 DK 0503453T3 DK 92103666 T DK92103666 T DK 92103666T DK 92103666 T DK92103666 T DK 92103666T DK 0503453 T3 DK0503453 T3 DK 0503453T3
Authority
DK
Denmark
Prior art keywords
intermediates
preparing cephalosporins
cephalosporins
preparing
vinylcephalosporin
Prior art date
Application number
DK92103666T
Other languages
English (en)
Inventor
Gerd Ascher
Hubert Sturm
Johannes Ludescher
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT50491A external-priority patent/AT396106B/de
Priority claimed from AT101891A external-priority patent/AT396238B/de
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Application granted granted Critical
Publication of DK0503453T3 publication Critical patent/DK0503453T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK92103666T 1991-03-08 1992-03-04 Fremgangsmåde til fremstilling af cephalosporiner og mellemprodukter i denne fremgangsmåde DK0503453T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT50491A AT396106B (de) 1991-03-08 1991-03-08 Neues verfahren zur herstellung von 3-vinylcephalosporinverbindungen
AT101891A AT396238B (de) 1991-05-17 1991-05-17 Neues verfahren und zwischenprodukte zur herstellung von 3-vinylcephalosporinverbindungen

Publications (1)

Publication Number Publication Date
DK0503453T3 true DK0503453T3 (da) 2001-07-16

Family

ID=25592974

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92103666T DK0503453T3 (da) 1991-03-08 1992-03-04 Fremgangsmåde til fremstilling af cephalosporiner og mellemprodukter i denne fremgangsmåde

Country Status (9)

Country Link
US (1) US5401841A (da)
EP (1) EP0503453B1 (da)
JP (2) JP2766116B2 (da)
AT (1) ATE201025T1 (da)
DE (1) DE69231815T2 (da)
DK (1) DK0503453T3 (da)
ES (1) ES2157199T3 (da)
GR (1) GR3036070T3 (da)
PT (1) PT503453E (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248881B1 (en) 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
AT400436B (de) * 1992-11-10 1995-12-27 Biochemie Gmbh Neues verfahren zur herstellung von 3-vinylcephalosporinverbindungen
AT399876B (de) * 1992-02-05 1995-08-25 Biochemie Gmbh Verfahren zur abreicherung von 7-amino-3-((e)-1- propen-1-yl)-3-cephem-4-carbonsäure
ATE253583T1 (de) 1992-02-05 2003-11-15 Biochemie Gmbh Verfahren zur herstellung von einem 3-cephem-4- carbonsäurederivat
JPH07173168A (ja) * 1993-07-14 1995-07-11 Sumitomo Chem Co Ltd セフェム系化合物、その製法、およびそれのセフェム系抗生物質製造への利用
ATE198892T1 (de) * 1993-11-17 2001-02-15 Biochemie Gmbh Trennung von cephalosporinisomeren
US5856474A (en) * 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis
AT403049B (de) * 1995-08-14 1997-10-27 Biochemie Gmbh Abreicherung von 7-adca in 3-vinyl-aca
ID28433A (id) 1998-06-22 2001-05-24 Hoffmann La Roche Turunan propenil sefalosporin
KR100441901B1 (ko) * 2001-07-02 2004-07-27 일동제약주식회사 세팔로스포린 유도체의 개선된 제조방법
AU2003267733A1 (en) * 2002-10-08 2004-05-04 Ranbaxy Laboratories Limited Process for the preparation of (z)-isomer enriched 7-amino-3-propen-1-yl-3-cephem-4- carboxylic acid
WO2005042543A1 (en) 2003-10-30 2005-05-12 Cj Corporation Processes for the preparation of cephem derivatives
JP2006096679A (ja) * 2004-09-28 2006-04-13 Meiji Seika Kaisha Ltd セファロスポリン化合物の製造方法
WO2007013043A2 (en) * 2005-07-29 2007-02-01 Ranbaxy Laboratories Limited Processes for the preparation of 7-amino-3-vinyl cephalosporanic acid
JP5733856B2 (ja) 2007-10-09 2015-06-10 ソファーミア，インコーポレイテッド 広帯域β−ラクタマーゼ阻害薬
WO2010082108A1 (en) * 2009-01-16 2010-07-22 Nectar Lifesciences Ltd. Improved process for preparation of key intermediate of cephalosporins
EP2968352B1 (en) 2013-03-12 2018-09-26 Gladius Pharmaceuticals Corporation Derivatized 3-styryl-cephalosporins

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769277A (en) 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
US4110534A (en) * 1970-01-23 1978-08-29 Glaxo Laboratories Limited Process for the preparation of 3-vinyl and substituted vinyl cephalosporins
GB1532682A (en) 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
CA1213882A (en) 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
GB2152497B (en) 1983-11-28 1987-08-05 Otsuka Kagaku Kk Process for the preparation of azetidinone derivatives
US4705851A (en) 1984-09-28 1987-11-10 Fujisawa Pharmaceutical Co., Ltd. Process for the preparation of 3-phosphoniummethyl-3-cephem compounds
AT382872B (de) 1984-11-23 1987-04-27 Biochemie Gmbh Verfahren zur herstellung von cephalosporinderivaten
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
FR2580652B1 (fr) * 1985-04-22 1989-01-06 Bristol Myers Co Acide 7-amino-3-propenylcephalosporanique et ses esters
DE3734004A1 (de) 1987-05-26 1988-12-15 Bayer Ag Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3933934A1 (de) * 1989-10-03 1991-04-11 Bayer Ag Verfahren zur herstellung von 7-amino-3-((z)-1-propen-1-yl)-3-cephem-4-carbonsaeure

Also Published As

Publication number Publication date
JPH04327590A (ja) 1992-11-17
JP2766116B2 (ja) 1998-06-18
EP0503453B1 (en) 2001-05-09
PT503453E (pt) 2001-10-31
JPH08283273A (ja) 1996-10-29
ES2157199T3 (es) 2001-08-16
ATE201025T1 (de) 2001-05-15
DE69231815T2 (de) 2001-09-27
DE69231815D1 (de) 2001-06-13
EP0503453A2 (en) 1992-09-16
EP0503453A3 (en) 1992-12-09
JP2740497B2 (ja) 1998-04-15
US5401841A (en) 1995-03-28
GR3036070T3 (en) 2001-09-28

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment