ATE201025T1 - Verfahren zur herstellung von cephalosporinen und zwischenprodukte in diesem verfahren - Google Patents
Verfahren zur herstellung von cephalosporinen und zwischenprodukte in diesem verfahrenInfo
- Publication number
- ATE201025T1 ATE201025T1 AT92103666T AT92103666T ATE201025T1 AT E201025 T1 ATE201025 T1 AT E201025T1 AT 92103666 T AT92103666 T AT 92103666T AT 92103666 T AT92103666 T AT 92103666T AT E201025 T1 ATE201025 T1 AT E201025T1
- Authority
- AT
- Austria
- Prior art keywords
- intermediate products
- producing cephalosporins
- cephalosporins
- producing
- vinylcephalosporin
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
- 239000013067 intermediate product Substances 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT50491A AT396106B (de) | 1991-03-08 | 1991-03-08 | Neues verfahren zur herstellung von 3-vinylcephalosporinverbindungen |
| AT101891A AT396238B (de) | 1991-05-17 | 1991-05-17 | Neues verfahren und zwischenprodukte zur herstellung von 3-vinylcephalosporinverbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE201025T1 true ATE201025T1 (de) | 2001-05-15 |
Family
ID=25592974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92103666T ATE201025T1 (de) | 1991-03-08 | 1992-03-04 | Verfahren zur herstellung von cephalosporinen und zwischenprodukte in diesem verfahren |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5401841A (de) |
| EP (1) | EP0503453B1 (de) |
| JP (2) | JP2766116B2 (de) |
| AT (1) | ATE201025T1 (de) |
| DE (1) | DE69231815T2 (de) |
| DK (1) | DK0503453T3 (de) |
| ES (1) | ES2157199T3 (de) |
| GR (1) | GR3036070T3 (de) |
| PT (1) | PT503453E (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6248881B1 (en) * | 1991-03-08 | 2001-06-19 | Biochemie Gmbh | Intermediates and process for the production of 3-vinyl cephalosporins |
| AT400436B (de) * | 1992-11-10 | 1995-12-27 | Biochemie Gmbh | Neues verfahren zur herstellung von 3-vinylcephalosporinverbindungen |
| AT399876B (de) * | 1992-02-05 | 1995-08-25 | Biochemie Gmbh | Verfahren zur abreicherung von 7-amino-3-((e)-1- propen-1-yl)-3-cephem-4-carbonsäure |
| PT630380E (pt) * | 1992-02-05 | 2002-02-28 | Biochemie Gmbh | Processo para a purificacao de um derivado do acido 3-cefem-4-carboxilico |
| JPH07173168A (ja) * | 1993-07-14 | 1995-07-11 | Sumitomo Chem Co Ltd | セフェム系化合物、その製法、およびそれのセフェム系抗生物質製造への利用 |
| EP0658558B1 (de) * | 1993-11-17 | 2001-01-24 | Biochemie Gesellschaft M.B.H. | Trennung von Cephalosporinisomeren |
| US5856474A (en) * | 1994-04-25 | 1999-01-05 | Biochemie Gesellschaft, M.B.H. | Cephalosporin synthesis |
| AT403049B (de) * | 1995-08-14 | 1997-10-27 | Biochemie Gmbh | Abreicherung von 7-adca in 3-vinyl-aca |
| CA2335288A1 (en) | 1998-06-22 | 1999-12-29 | F. Hoffmann-La Roche Ag | Propenyl cephalosporin derivatives |
| KR100441901B1 (ko) * | 2001-07-02 | 2004-07-27 | 일동제약주식회사 | 세팔로스포린 유도체의 개선된 제조방법 |
| EP1554288A1 (de) * | 2002-10-08 | 2005-07-20 | Ranbaxy Laboratories, Ltd. | Verfahren zur herstellung von (z)-isomer angereichertem 7-amino-3-propen-1-yl-3-cephem-4-carbonsäure |
| WO2005042543A1 (en) * | 2003-10-30 | 2005-05-12 | Cj Corporation | Processes for the preparation of cephem derivatives |
| JP2006096679A (ja) * | 2004-09-28 | 2006-04-13 | Meiji Seika Kaisha Ltd | セファロスポリン化合物の製造方法 |
| WO2007013043A2 (en) * | 2005-07-29 | 2007-02-01 | Ranbaxy Laboratories Limited | Processes for the preparation of 7-amino-3-vinyl cephalosporanic acid |
| CA2702257C (en) | 2007-10-09 | 2016-07-12 | Sopharmia, Inc. | Broad spectrum beta-lactamase inhibitors |
| WO2010082108A1 (en) * | 2009-01-16 | 2010-07-22 | Nectar Lifesciences Ltd. | Improved process for preparation of key intermediate of cephalosporins |
| ES2700575T3 (es) | 2013-03-12 | 2019-02-18 | Gladius Pharmaceuticals Corp | 3-Estiril-cefalosporinas derivadas |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3769277A (en) | 1970-01-23 | 1973-10-30 | Glaxo Lab Ltd | Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group |
| US4110534A (en) * | 1970-01-23 | 1978-08-29 | Glaxo Laboratories Limited | Process for the preparation of 3-vinyl and substituted vinyl cephalosporins |
| GB1532682A (en) | 1976-04-27 | 1978-11-22 | Bristol Myers Co | Process for the preparation of cephadroxil |
| CA1213882A (en) | 1982-03-04 | 1986-11-12 | Jun Okumura | Cephalosporins |
| GB2152497B (en) | 1983-11-28 | 1987-08-05 | Otsuka Kagaku Kk | Process for the preparation of azetidinone derivatives |
| US4705851A (en) | 1984-09-28 | 1987-11-10 | Fujisawa Pharmaceutical Co., Ltd. | Process for the preparation of 3-phosphoniummethyl-3-cephem compounds |
| AT382873B (de) | 1984-11-23 | 1987-04-27 | Biochemie Gmbh | Verfahren zur herstellung von cephalosporinderivaten |
| US4703118A (en) * | 1985-04-08 | 1987-10-27 | Eli Lilly And Company | Synthesis of 3-iodomethyl cephalosporins |
| FR2580652B1 (fr) * | 1985-04-22 | 1989-01-06 | Bristol Myers Co | Acide 7-amino-3-propenylcephalosporanique et ses esters |
| DE3734004A1 (de) | 1987-05-26 | 1988-12-15 | Bayer Ag | Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3933934A1 (de) * | 1989-10-03 | 1991-04-11 | Bayer Ag | Verfahren zur herstellung von 7-amino-3-((z)-1-propen-1-yl)-3-cephem-4-carbonsaeure |
-
1992
- 1992-03-04 DK DK92103666T patent/DK0503453T3/da not_active Application Discontinuation
- 1992-03-04 PT PT92103666T patent/PT503453E/pt unknown
- 1992-03-04 DE DE69231815T patent/DE69231815T2/de not_active Expired - Fee Related
- 1992-03-04 ES ES92103666T patent/ES2157199T3/es not_active Expired - Lifetime
- 1992-03-04 EP EP92103666A patent/EP0503453B1/de not_active Expired - Lifetime
- 1992-03-04 AT AT92103666T patent/ATE201025T1/de not_active IP Right Cessation
- 1992-03-06 JP JP4049427A patent/JP2766116B2/ja not_active Expired - Lifetime
-
1993
- 1993-05-28 US US08/069,239 patent/US5401841A/en not_active Expired - Lifetime
-
1996
- 1996-04-17 JP JP8095567A patent/JP2740497B2/ja not_active Expired - Lifetime
-
2001
- 2001-06-19 GR GR20010400913T patent/GR3036070T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK0503453T3 (da) | 2001-07-16 |
| JP2766116B2 (ja) | 1998-06-18 |
| JP2740497B2 (ja) | 1998-04-15 |
| JPH08283273A (ja) | 1996-10-29 |
| DE69231815T2 (de) | 2001-09-27 |
| US5401841A (en) | 1995-03-28 |
| EP0503453A3 (en) | 1992-12-09 |
| DE69231815D1 (de) | 2001-06-13 |
| EP0503453A2 (de) | 1992-09-16 |
| EP0503453B1 (de) | 2001-05-09 |
| JPH04327590A (ja) | 1992-11-17 |
| ES2157199T3 (es) | 2001-08-16 |
| GR3036070T3 (en) | 2001-09-28 |
| PT503453E (pt) | 2001-10-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE201025T1 (de) | Verfahren zur herstellung von cephalosporinen und zwischenprodukte in diesem verfahren | |
| ATE137493T1 (de) | Verfahren zur herstellung von zwischenprodukten zur verwendung in der herstellung von alkoxyiminoacetamide | |
| DE69200983D1 (de) | Verfahren zur Herstellung von Wasserstoffsuperoxyd. | |
| DE69204484D1 (de) | Verfahren zur Herstellung von Wasserstoffperoxyd. | |
| DE69101775D1 (de) | Verfahren zur Herstellung von Wasserstoffperoxid. | |
| DE69203959D1 (de) | Verfahren zur Herstellung von Prepregs. | |
| DE69203767D1 (de) | Verfahren zur Herstellung von organischen Düngemitteln. | |
| DE69233106D1 (de) | Verfahren zur Herstellung von Einzelsträndigen "stem-loop" DNS | |
| ATE154003T1 (de) | Verfahren zur herstellung von (e)-alkoximino- oder hydroxyiminoacetamidverbindungen und zwischenprodukte | |
| DE69221841D1 (de) | Verfahren zur Herstellung von gereinigtem Xanthangummi | |
| DE69213916D1 (de) | Verfahren zur Herstellung von L-Ambrox | |
| DE69428845D1 (de) | Verfahren zur Herstellung von Sende-Empfängern | |
| DE69202680D1 (de) | Verfahren zur Herstellung von Wasserstoffperoxyd. | |
| DE69217346D1 (de) | Verfahren zur Herstellung von Mikroleuchtkörpern | |
| DE69314445D1 (de) | Verfahren zur Herstellung von Wasserstoffperoxyd | |
| DE69202419D1 (de) | Verfahren zur Herstellung von Fulleren. | |
| DE69228648D1 (de) | Verfahren zur Herstellung von komplementären, bipolaren Transistoren | |
| ATE175957T1 (de) | Verfahren zur herstellung von alkoxyiminoacetamid-verbindungen | |
| DE69225560D1 (de) | Verfahren zur Herstellung von Lactonen | |
| ATE109446T1 (de) | Verfahren zur herstellung von terpenketonen. | |
| DE69204501D1 (de) | Verfahren zur Herstellung von Oxamid. | |
| DE69811893D1 (de) | Verfahren zur herstellung von azetidin-2-carbonsäure und zwischenprodukten davon | |
| DE59201325D1 (de) | Verbessertes Verfahren zur Herstellung von Polyenen. | |
| DE69317237D1 (de) | Verfahren zur Herstellung von abriebfesten, transparenten Teilen | |
| ATE233267T1 (de) | Verfahren zur herstellung von 3- vinylcephalosporinen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |