DK0399748T3 - Fremgangsmåde til fremstilling af 2-oxindol-1-carboxamider - Google Patents
Fremgangsmåde til fremstilling af 2-oxindol-1-carboxamiderInfo
- Publication number
- DK0399748T3 DK0399748T3 DK90305464.1T DK90305464T DK0399748T3 DK 0399748 T3 DK0399748 T3 DK 0399748T3 DK 90305464 T DK90305464 T DK 90305464T DK 0399748 T3 DK0399748 T3 DK 0399748T3
- Authority
- DK
- Denmark
- Prior art keywords
- oxindole
- carboxamides
- preparation
- agents
- trichloracetyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/357,138 US4952703A (en) | 1989-05-25 | 1989-05-25 | Intermediates for making 2-oxindole-1-carboxamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0399748T3 true DK0399748T3 (da) | 1996-02-12 |
Family
ID=23404454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90305464.1T DK0399748T3 (da) | 1989-05-25 | 1990-05-21 | Fremgangsmåde til fremstilling af 2-oxindol-1-carboxamider |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4952703A (da) |
| EP (1) | EP0399748B1 (da) |
| JP (2) | JPH07119211B2 (da) |
| AT (1) | ATE133409T1 (da) |
| CA (1) | CA2017328A1 (da) |
| DE (1) | DE69024999T2 (da) |
| DK (1) | DK0399748T3 (da) |
| ES (1) | ES2083427T3 (da) |
| FI (1) | FI902590A7 (da) |
| GR (1) | GR3019276T3 (da) |
| IE (1) | IE70066B1 (da) |
| PT (1) | PT94127B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5086186A (en) * | 1989-05-25 | 1992-02-04 | Pfizer Inc. | N-trichloroacetyl-2-oxindole-1-carboxamides |
| DE69305999T2 (de) * | 1993-02-09 | 1997-03-06 | Pfizer Inc., New York, N.Y. | Oxindol 1-[n-(alkoxycarbonyl)]carboxamide und 1-[n-carboxamido]carboxamide als antiinflammatorische wirkstoffe |
| US5449788A (en) * | 1994-01-28 | 1995-09-12 | Catalytica, Inc. | Process for preparing 2-oxindole-1-carboxamides |
| BR9714145B1 (pt) * | 1996-12-18 | 2009-05-05 | composto ou seu sal farmaceuticamente aceitável e composição farmacêutica compreendendo o mencionado composto. | |
| CN103242304A (zh) * | 2013-05-21 | 2013-08-14 | 苏州科捷生物医药有限公司 | 消炎药替尼达普钠的合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4471119A (en) * | 1981-10-10 | 1984-09-11 | Fisons Plc | Certain hydrolysis or reductive cleavage reaction involving 4h-pyrano(3,2-g) quinoline-2,8-dicarboxylic acid derivatives |
| IN163263B (da) * | 1984-02-07 | 1988-08-27 | Pfizer | |
| GR850669B (da) * | 1984-03-19 | 1985-07-25 | Pfizer | |
| US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
| US4665194A (en) * | 1984-12-21 | 1987-05-12 | Pfizer Inc. | Process for making 2-oxindole-1-carboxamides and intermediates therefor |
| EP0303418A3 (en) * | 1987-08-11 | 1990-11-07 | Smithkline Beecham Laboratoires Pharmaceutiques | Substituted indolones, useful in the treatment of heart or asthmatic diseases |
-
1989
- 1989-05-25 US US07/357,138 patent/US4952703A/en not_active Expired - Lifetime
-
1990
- 1990-05-21 EP EP90305464A patent/EP0399748B1/en not_active Expired - Lifetime
- 1990-05-21 DE DE69024999T patent/DE69024999T2/de not_active Expired - Fee Related
- 1990-05-21 DK DK90305464.1T patent/DK0399748T3/da active
- 1990-05-21 ES ES90305464T patent/ES2083427T3/es not_active Expired - Lifetime
- 1990-05-21 AT AT90305464T patent/ATE133409T1/de not_active IP Right Cessation
- 1990-05-23 CA CA002017328A patent/CA2017328A1/en not_active Abandoned
- 1990-05-23 PT PT94127A patent/PT94127B/pt not_active IP Right Cessation
- 1990-05-24 FI FI902590A patent/FI902590A7/fi not_active Application Discontinuation
- 1990-05-24 JP JP2135177A patent/JPH07119211B2/ja not_active Expired - Lifetime
- 1990-05-24 IE IE187190A patent/IE70066B1/en not_active IP Right Cessation
-
1994
- 1994-11-28 JP JP6293236A patent/JP2500853B2/ja not_active Expired - Lifetime
-
1996
- 1996-03-12 GR GR960400679T patent/GR3019276T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07215935A (ja) | 1995-08-15 |
| US4952703A (en) | 1990-08-28 |
| IE70066B1 (en) | 1996-10-30 |
| PT94127A (pt) | 1991-01-08 |
| CA2017328A1 (en) | 1990-11-25 |
| EP0399748B1 (en) | 1996-01-24 |
| JPH07119211B2 (ja) | 1995-12-20 |
| EP0399748A3 (en) | 1992-01-08 |
| GR3019276T3 (en) | 1996-06-30 |
| ATE133409T1 (de) | 1996-02-15 |
| PT94127B (pt) | 1997-01-31 |
| DE69024999D1 (de) | 1996-03-07 |
| DE69024999T2 (de) | 1996-05-30 |
| ES2083427T3 (es) | 1996-04-16 |
| JP2500853B2 (ja) | 1996-05-29 |
| JPH0311061A (ja) | 1991-01-18 |
| FI902590A7 (fi) | 1990-11-26 |
| IE901871L (en) | 1990-11-25 |
| FI902590A0 (fi) | 1990-05-24 |
| EP0399748A2 (en) | 1990-11-28 |
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