DK0979822T3 - Fremgangsmåde til fremstilling af 2-carbamoyl-pyridiner - Google Patents
Fremgangsmåde til fremstilling af 2-carbamoyl-pyridinerInfo
- Publication number
- DK0979822T3 DK0979822T3 DK99114893T DK99114893T DK0979822T3 DK 0979822 T3 DK0979822 T3 DK 0979822T3 DK 99114893 T DK99114893 T DK 99114893T DK 99114893 T DK99114893 T DK 99114893T DK 0979822 T3 DK0979822 T3 DK 0979822T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- pyridines
- carbamoyl
- carbamoylation
- concerned
- Prior art date
Links
- IBBMAWULFFBRKK-UHFFFAOYSA-N picolinamide Chemical class NC(=O)C1=CC=CC=N1 IBBMAWULFFBRKK-UHFFFAOYSA-N 0.000 title 1
- 230000021235 carbamoylation Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000003222 pyridines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98114978 | 1998-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0979822T3 true DK0979822T3 (da) | 2006-03-27 |
Family
ID=8232437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99114893T DK0979822T3 (da) | 1998-08-10 | 1999-07-30 | Fremgangsmåde til fremstilling af 2-carbamoyl-pyridiner |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6103902A (da) |
| EP (1) | EP0979822B1 (da) |
| JP (1) | JP3344972B2 (da) |
| KR (1) | KR100362081B1 (da) |
| CN (1) | CN1117746C (da) |
| AT (1) | ATE311382T1 (da) |
| CA (1) | CA2279796C (da) |
| DE (1) | DE69928610T2 (da) |
| DK (1) | DK0979822T3 (da) |
| ES (1) | ES2252894T3 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6670362B2 (en) | 2000-09-20 | 2003-12-30 | Pfizer Inc. | Pyridazine endothelin antagonists |
| WO2016134854A1 (en) * | 2015-02-25 | 2016-09-01 | Pharmathen S.A. | Methods for the preparation of topiroxostat and intermediates thereof |
| CN105669542A (zh) * | 2016-03-08 | 2016-06-15 | 南京师范大学 | 一种直接催化氧化法合成吡啶伯酰胺化合物的方法 |
| CA3197265A1 (en) | 2020-11-05 | 2022-05-12 | Timo Rager | A stable crystalline hydrate of clazosentan disodium salt |
| WO2023111299A1 (en) | 2021-12-17 | 2023-06-22 | Idorsia Pharmaceuticals Ltd | Clazosentan disodium salt, its preparation and pharmaceutical compositions comprising the same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW313568B (da) * | 1994-12-20 | 1997-08-21 | Hoffmann La Roche |
-
1999
- 1999-07-30 DK DK99114893T patent/DK0979822T3/da active
- 1999-07-30 AT AT99114893T patent/ATE311382T1/de active
- 1999-07-30 DE DE69928610T patent/DE69928610T2/de not_active Expired - Lifetime
- 1999-07-30 ES ES99114893T patent/ES2252894T3/es not_active Expired - Lifetime
- 1999-07-30 EP EP99114893A patent/EP0979822B1/en not_active Expired - Lifetime
- 1999-08-06 CA CA002279796A patent/CA2279796C/en not_active Expired - Lifetime
- 1999-08-09 KR KR1019990032563A patent/KR100362081B1/ko not_active Expired - Lifetime
- 1999-08-09 US US09/370,817 patent/US6103902A/en not_active Expired - Lifetime
- 1999-08-09 CN CN99117533A patent/CN1117746C/zh not_active Expired - Lifetime
- 1999-08-10 JP JP22600399A patent/JP3344972B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6103902A (en) | 2000-08-15 |
| CA2279796A1 (en) | 2000-02-10 |
| ES2252894T3 (es) | 2006-05-16 |
| JP2000063377A (ja) | 2000-02-29 |
| DE69928610T2 (de) | 2006-08-10 |
| ATE311382T1 (de) | 2005-12-15 |
| CN1245803A (zh) | 2000-03-01 |
| CN1117746C (zh) | 2003-08-13 |
| DE69928610D1 (de) | 2006-01-05 |
| EP0979822A1 (en) | 2000-02-16 |
| CA2279796C (en) | 2003-09-30 |
| JP3344972B2 (ja) | 2002-11-18 |
| KR20000017194A (ko) | 2000-03-25 |
| EP0979822B1 (en) | 2005-11-30 |
| KR100362081B1 (ko) | 2002-11-23 |
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