IL95120A - Preparation of sustained release pharmaceutical compositions comprising peptide salts, in the form of microparticles - Google Patents

Preparation of sustained release pharmaceutical compositions comprising peptide salts, in the form of microparticles

Info

Publication number
IL95120A
IL95120A IL9512090A IL9512090A IL95120A IL 95120 A IL95120 A IL 95120A IL 9512090 A IL9512090 A IL 9512090A IL 9512090 A IL9512090 A IL 9512090A IL 95120 A IL95120 A IL 95120A
Authority
IL
Israel
Prior art keywords
trp
cys
phe
microparticles
thr
Prior art date
Application number
IL9512090A
Other languages
English (en)
Other versions
IL95120A0 (en
Original Assignee
Debiopharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Sa filed Critical Debiopharm Sa
Publication of IL95120A0 publication Critical patent/IL95120A0/xx
Publication of IL95120A publication Critical patent/IL95120A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
IL9512090A 1989-07-28 1990-07-18 Preparation of sustained release pharmaceutical compositions comprising peptide salts, in the form of microparticles IL95120A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2829/89A CH679207A5 (instruction) 1989-07-28 1989-07-28

Publications (2)

Publication Number Publication Date
IL95120A0 IL95120A0 (en) 1991-06-10
IL95120A true IL95120A (en) 1994-10-07

Family

ID=4242536

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9512090A IL95120A (en) 1989-07-28 1990-07-18 Preparation of sustained release pharmaceutical compositions comprising peptide salts, in the form of microparticles

Country Status (23)

Country Link
US (1) US5134122A (instruction)
JP (1) JPH0662427B2 (instruction)
AT (1) AT397197B (instruction)
AU (1) AU619996B2 (instruction)
BE (1) BE1003093A3 (instruction)
CA (1) CA2021767C (instruction)
CH (1) CH679207A5 (instruction)
DE (1) DE4023134C2 (instruction)
DK (1) DK175495B1 (instruction)
ES (1) ES2020890A6 (instruction)
FI (1) FI97688C (instruction)
FR (1) FR2650182B1 (instruction)
GB (1) GB2234169B (instruction)
GR (1) GR1001215B (instruction)
IE (1) IE65397B1 (instruction)
IL (1) IL95120A (instruction)
IT (1) IT1243357B (instruction)
LU (1) LU87772A1 (instruction)
NL (1) NL194858C (instruction)
NO (1) NO300304B1 (instruction)
PT (1) PT94842B (instruction)
SE (1) SE504279C2 (instruction)
ZA (1) ZA905654B (instruction)

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PH30995A (en) * 1989-07-07 1997-12-23 Novartis Inc Sustained release formulations of water soluble peptides.
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US6517859B1 (en) 1990-05-16 2003-02-11 Southern Research Institute Microcapsules for administration of neuroactive agents
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CH683149A5 (fr) * 1991-07-22 1994-01-31 Debio Rech Pharma Sa Procédé pour la préparation de microsphères en matériau polymère biodégradable.
US5470582A (en) * 1992-02-07 1995-11-28 Syntex (U.S.A.) Inc. Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
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US5456917A (en) * 1993-04-12 1995-10-10 Cambridge Scientific, Inc. Method for making a bioerodible material for the sustained release of a medicament and the material made from the method
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US5569468A (en) * 1994-02-17 1996-10-29 Modi; Pankaj Vaccine delivery system for immunization, using biodegradable polymer microspheres
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Also Published As

Publication number Publication date
NL9001646A (nl) 1991-02-18
GR1001215B (el) 1993-06-21
IL95120A0 (en) 1991-06-10
CA2021767C (en) 1996-10-22
NL194858B (nl) 2003-01-06
GB9015722D0 (en) 1990-09-05
ZA905654B (en) 1991-05-29
NO903264L (no) 1991-01-29
SE9002522D0 (sv) 1990-07-27
AU619996B2 (en) 1992-02-06
GB2234169A (en) 1991-01-30
DK175495B1 (da) 2004-11-08
IT1243357B (it) 1994-06-10
LU87772A1 (fr) 1990-12-11
ATA154590A (de) 1993-07-15
CA2021767A1 (en) 1991-01-29
DK180790D0 (da) 1990-07-27
PT94842B (pt) 1997-04-30
FI97688B (fi) 1996-10-31
DK180790A (da) 1991-01-29
FI97688C (fi) 1997-02-10
ES2020890A6 (es) 1991-10-01
JPH0662427B2 (ja) 1994-08-17
AU5910390A (en) 1991-01-31
NO903264D0 (no) 1990-07-23
IT9021019A1 (it) 1992-01-23
IE902592A1 (en) 1991-02-27
FR2650182A1 (fr) 1991-02-01
DE4023134C2 (de) 1997-04-17
NO300304B1 (no) 1997-05-12
GR900100568A (en) 1991-12-10
FI903643A0 (fi) 1990-07-19
US5134122A (en) 1992-07-28
BE1003093A3 (fr) 1991-11-19
SE9002522L (sv) 1991-01-29
JPH0366625A (ja) 1991-03-22
IE65397B1 (en) 1995-10-18
GB2234169B (en) 1993-02-10
DE4023134A1 (de) 1991-01-31
CH679207A5 (instruction) 1992-01-15
AT397197B (de) 1994-02-25
SE504279C2 (sv) 1996-12-23
IT9021019A0 (it) 1990-07-23
NL194858C (nl) 2003-05-06
FR2650182B1 (fr) 1992-05-15
PT94842A (pt) 1991-03-20

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