IL93732A - History of the noble N-LL-88233 Antibiotics against tumors and their preparation - Google Patents

History of the noble N-LL-88233 Antibiotics against tumors and their preparation

Info

Publication number
IL93732A
IL93732A IL9373290A IL9373290A IL93732A IL 93732 A IL93732 A IL 93732A IL 9373290 A IL9373290 A IL 9373290A IL 9373290 A IL9373290 A IL 9373290A IL 93732 A IL93732 A IL 93732A
Authority
IL
Israel
Prior art keywords
ethyl acetate
taken together
phenazlnyl
acetyl
compound
Prior art date
Application number
IL9373290A
Other languages
English (en)
Hebrew (he)
Other versions
IL93732A0 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IL93732A0 publication Critical patent/IL93732A0/xx
Publication of IL93732A publication Critical patent/IL93732A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL9373290A 1989-04-14 1990-03-13 History of the noble N-LL-88233 Antibiotics against tumors and their preparation IL93732A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/338,928 US5079233A (en) 1987-01-30 1989-04-14 N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same

Publications (2)

Publication Number Publication Date
IL93732A0 IL93732A0 (en) 1990-12-23
IL93732A true IL93732A (en) 1994-11-28

Family

ID=23326735

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9373290A IL93732A (en) 1989-04-14 1990-03-13 History of the noble N-LL-88233 Antibiotics against tumors and their preparation

Country Status (23)

Country Link
US (1) US5079233A (ko)
EP (2) EP0392376B1 (ko)
JP (1) JP3083309B2 (ko)
KR (1) KR0149493B1 (ko)
CN (1) CN1027267C (ko)
AT (2) ATE297405T1 (ko)
AU (1) AU627863B2 (ko)
CA (1) CA2014472C (ko)
CZ (2) CZ284618B6 (ko)
DE (2) DE69033839T2 (ko)
DK (2) DK0392376T3 (ko)
ES (2) ES2240000T3 (ko)
FI (1) FI97889C (ko)
HK (2) HK1035540A1 (ko)
IE (1) IE20011013A1 (ko)
IL (1) IL93732A (ko)
NO (1) NO172938C (ko)
NZ (1) NZ233149A (ko)
PH (1) PH27361A (ko)
PT (1) PT93715B (ko)
SG (1) SG47857A1 (ko)
SK (1) SK188390A3 (ko)
ZA (1) ZA902839B (ko)

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Publication number Priority date Publication date Assignee Title
JPS5644076B2 (ko) * 1973-07-12 1981-10-16
ES2177518T3 (es) * 1987-01-30 2002-12-16 American Cyanamid Co Derivados dihidro de los antibioticos ll-e33288.
US4837206A (en) * 1987-04-29 1989-06-06 Bristol-Myers Company Esperamicin derivatives
EP0313873B1 (en) * 1987-10-30 1994-09-28 American Cyanamid Company Targeted forms of methyltrithio antitumor agents
IL93733A (en) * 1989-04-14 1996-01-19 American Cyanamid Co History of Dissolved Drug Sulphides Antibacterial and Antibacterial, Prepared from Compounds Containing Methyl-Thriteo Groups and Their Target Form

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KR0149493B1 (ko) 1998-08-17
ATE207926T1 (de) 2001-11-15
ES2240000T3 (es) 2005-10-16
ES2162783T3 (es) 2002-01-16
US5079233A (en) 1992-01-07
CZ53598A3 (cs) 1998-09-16
SG47857A1 (en) 1998-04-17
EP0392376A2 (en) 1990-10-17
SK281179B6 (sk) 2000-12-11
CA2014472C (en) 2000-03-28
FI97889B (fi) 1996-11-29
NO172938B (no) 1993-06-21
IE20011013A1 (en) 2002-12-30
PH27361A (en) 1993-06-21
PT93715A (pt) 1990-11-20
CN1048390A (zh) 1991-01-09
SK188390A3 (en) 2000-12-11
DK0392376T3 (da) 2001-12-03
NZ233149A (en) 1996-02-27
PT93715B (pt) 1996-08-30
ZA902839B (en) 1991-12-24
CZ188390A3 (cs) 1998-10-14
FI97889C (fi) 1997-03-10
NO172938C (no) 1993-12-29
CN1027267C (zh) 1995-01-04
IL93732A0 (en) 1990-12-23
ATE297405T1 (de) 2005-06-15
CZ284618B6 (cs) 1999-01-13
KR900016242A (ko) 1990-11-13
NO901654D0 (no) 1990-04-11
JP3083309B2 (ja) 2000-09-04
FI901865A0 (fi) 1990-05-12
EP0392376B1 (en) 2001-10-31
DE69034194T2 (de) 2005-11-03
EP1097937A1 (en) 2001-05-09
DE69033839T2 (de) 2002-06-06
DE69034194D1 (de) 2005-07-14
AU5324890A (en) 1990-10-18
CA2014472A1 (en) 1990-10-14
DK1097937T3 (da) 2005-09-19
JPH032192A (ja) 1991-01-08
HK1035540A1 (en) 2001-11-30
NO901654L (no) 1990-10-15
CZ297668B6 (cs) 2007-02-28
EP1097937B1 (en) 2005-06-08
DE69033839D1 (de) 2001-12-06
AU627863B2 (en) 1992-09-03
HK1011368A1 (en) 1999-07-09
EP0392376A3 (en) 1991-08-14

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