IL85277A - Al-Mimi sodium salt, crystals of 5-chloro-3-) 2-methanol (-2-oxaindole-1 and its preparation - Google Patents

Al-Mimi sodium salt, crystals of 5-chloro-3-) 2-methanol (-2-oxaindole-1 and its preparation

Info

Publication number
IL85277A
IL85277A IL8527788A IL8527788A IL85277A IL 85277 A IL85277 A IL 85277A IL 8527788 A IL8527788 A IL 8527788A IL 8527788 A IL8527788 A IL 8527788A IL 85277 A IL85277 A IL 85277A
Authority
IL
Israel
Prior art keywords
oxindole
carboxamide
sodium salt
chloro
thenoyl
Prior art date
Application number
IL8527788A
Other languages
English (en)
Hebrew (he)
Other versions
IL85277A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL85277A0 publication Critical patent/IL85277A0/xx
Publication of IL85277A publication Critical patent/IL85277A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL8527788A 1987-02-02 1988-02-01 Al-Mimi sodium salt, crystals of 5-chloro-3-) 2-methanol (-2-oxaindole-1 and its preparation IL85277A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/000201 WO1988005656A1 (en) 1987-02-02 1987-02-02 Anhydrous, crystalline sodium salt of 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamide

Publications (2)

Publication Number Publication Date
IL85277A0 IL85277A0 (en) 1988-07-31
IL85277A true IL85277A (en) 1994-02-27

Family

ID=22202263

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8527788A IL85277A (en) 1987-02-02 1988-02-01 Al-Mimi sodium salt, crystals of 5-chloro-3-) 2-methanol (-2-oxaindole-1 and its preparation

Country Status (42)

Country Link
US (1) US5036099A (sh)
EP (1) EP0277738B1 (sh)
JP (1) JPS63201184A (sh)
KR (1) KR900001422B1 (sh)
CN (1) CN1022324C (sh)
AP (1) AP52A (sh)
AR (1) AR243182A1 (sh)
AT (1) ATE73800T1 (sh)
AU (1) AU587736B2 (sh)
BG (1) BG51042A3 (sh)
CA (1) CA1335590C (sh)
CS (2) CS265250B2 (sh)
CY (1) CY1775A (sh)
DD (1) DD267490A5 (sh)
DE (1) DE3869149D1 (sh)
DK (1) DK44888A (sh)
EC (1) ECSP941082A (sh)
ES (1) ES2032955T3 (sh)
FI (1) FI89598C (sh)
GR (1) GR3004200T3 (sh)
HK (1) HK132695A (sh)
IE (1) IE60000B1 (sh)
IL (1) IL85277A (sh)
IN (1) IN171799B (sh)
IS (1) IS1533B (sh)
LV (1) LV10252B (sh)
MA (1) MA21171A1 (sh)
MY (1) MY102737A (sh)
NO (1) NO170581C (sh)
NZ (1) NZ223373A (sh)
OA (1) OA08710A (sh)
PH (1) PH26545A (sh)
PL (1) PL149550B1 (sh)
PT (1) PT86675B (sh)
RO (1) RO105052B1 (sh)
RU (1) RU2011381C1 (sh)
SG (1) SG27994G (sh)
SI (1) SI8810183A8 (sh)
UA (1) UA25898A1 (sh)
WO (1) WO1988005656A1 (sh)
YU (1) YU46766B (sh)
ZA (1) ZA88679B (sh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853409A (en) * 1988-04-13 1989-08-01 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
US4861794A (en) * 1988-04-13 1989-08-29 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
WO1990004393A1 (en) * 1988-10-18 1990-05-03 Pfizer Inc. Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides
EP0365194B1 (en) * 1988-10-18 1995-08-02 Pfizer Inc. Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides
US5059693A (en) * 1989-10-06 1991-10-22 Pfizer Inc. Process for making 3-aroyl-2-oxindole-1-carboxamides
US5006547A (en) * 1990-03-19 1991-04-09 Pfizer Inc. Tenidap as an inhibitor of the release of elastase by neutrophils
US5008283A (en) * 1990-03-19 1991-04-16 Pfizer Inc. Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
US5122534A (en) * 1991-02-08 1992-06-16 Pfizer Inc. Use of tenidap to reduce total serum cholesterol, ldl cholesterol and triglycerides
DE4111305C2 (de) * 1991-04-08 1994-12-01 Mack Chem Pharm Pharmazeutische Zubereitung zur rektalen Applikation, die ein 2-Oxindol-l-carboxamid-derivat enthält
AU7503496A (en) * 1995-12-19 1997-07-14 Pfizer Inc. Stable, long acting salts of indole derivatives for the treatment of joint diseases
EP0826685A1 (en) * 1996-08-21 1998-03-04 Pfizer Inc. Stable, long acting salts of carboxamides for the treatment of joint disease
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
US7407195B2 (en) 2004-04-14 2008-08-05 William Berson Label for receiving indicia having variable spectral emissivity values
US7651031B2 (en) * 2004-10-25 2010-01-26 William Berson Systems and methods for reading indicium
US7931413B2 (en) * 2005-01-14 2011-04-26 William Berson Printing system ribbon including print transferable circuitry and elements
US7621451B2 (en) * 2005-01-14 2009-11-24 William Berson Radio frequency identification labels and systems and methods for making the same
US7728726B2 (en) * 2005-01-14 2010-06-01 William Berson Radio frequency identification labels
US7619520B2 (en) * 2005-01-14 2009-11-17 William Berson Radio frequency identification labels and systems and methods for making the same
WO2019087191A1 (en) 2017-11-02 2019-05-09 Accurate Medical Therapeutics Ltd. Embolization catheter with integral filter

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3767653A (en) * 1971-06-28 1973-10-23 Squibb & Sons Inc Thiazines
GB1532413A (en) * 1974-12-23 1978-11-15 Union International Co Ltd Chenodeoxycholic acid
DE2613346C3 (de) * 1976-03-29 1981-07-23 Diamalt AG, 8000 München Monoklin kristalline Chenodesoxycholsäure und Verfahren zu ihrer Herstellung
DE3568776D1 (en) * 1984-02-07 1989-04-20 Pfizer 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
DE3579716D1 (de) * 1984-03-19 1990-10-25 Pfizer Verfahren zur herstellung von 2-oxindole-1-carboxamiden und deren zwischenprodukte.
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents

Also Published As

Publication number Publication date
YU18388A (en) 1989-10-31
RU2011381C1 (ru) 1994-04-30
IE60000B1 (en) 1994-05-18
SI8810183A8 (sl) 1996-08-31
CA1335590C (en) 1995-05-16
DE3869149D1 (de) 1992-04-23
ATE73800T1 (de) 1992-04-15
UA25898A1 (uk) 1999-02-26
IN171799B (sh) 1993-01-09
PT86675A (pt) 1988-03-01
MA21171A1 (fr) 1988-10-01
MY102737A (en) 1992-09-30
CS64888A2 (en) 1988-08-16
NO884329D0 (no) 1988-09-29
PH26545A (en) 1992-08-19
CN1022324C (zh) 1993-10-06
PL149550B1 (en) 1990-02-28
JPS63201184A (ja) 1988-08-19
LV10252B (en) 1995-04-20
FI893647A0 (fi) 1989-08-01
DK44888D0 (da) 1988-01-29
FI89598C (fi) 1993-10-25
PL270415A1 (en) 1988-12-08
CS354191A3 (en) 1992-04-15
BG51042A3 (en) 1993-01-15
PT86675B (pt) 1992-07-31
CS265250B2 (en) 1989-10-13
NO884329L (no) 1988-09-29
RO105052B1 (en) 1994-12-01
EP0277738A1 (en) 1988-08-10
IS3309A7 (is) 1988-08-03
KR880009961A (ko) 1988-10-06
SG27994G (en) 1994-10-14
AU587736B2 (en) 1989-08-24
LV10252A (lv) 1994-10-20
DD267490A5 (de) 1989-05-03
IE880269L (en) 1988-08-02
US5036099A (en) 1991-07-30
YU46766B (sh) 1994-05-10
NO170581B (no) 1992-07-27
NZ223373A (en) 1989-06-28
AU1116088A (en) 1988-08-04
KR900001422B1 (ko) 1990-03-09
OA08710A (fr) 1989-03-31
ES2032955T3 (es) 1996-07-16
DK44888A (da) 1988-08-03
WO1988005656A1 (en) 1988-08-11
EP0277738B1 (en) 1992-03-18
CY1775A (en) 1996-04-05
FI89598B (fi) 1993-07-15
AP8800081A0 (en) 1987-11-01
CN88100555A (zh) 1988-08-17
NO170581C (no) 1992-11-04
AR243182A1 (es) 1993-07-30
ZA88679B (en) 1989-09-27
ECSP941082A (es) 1994-12-15
HK132695A (en) 1995-09-01
GR3004200T3 (sh) 1993-03-31
IL85277A0 (en) 1988-07-31
AP52A (en) 1989-09-16
JPH0576945B2 (sh) 1993-10-25
IS1533B (is) 1994-01-28

Similar Documents

Publication Publication Date Title
US5036099A (en) Anhydrous, crystalline sodium salt of 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamide
CA2494528C (en) Racemization and enantiomer separation of clopidogrel
JP2001500878A (ja) オランザピン二水和物ｄ
RU2177000C2 (ru) Способ приготовления амлодипин бензолсульфоната
JPH0313233B2 (sh)
ZA200509155B (en) Pioglitazone salts, such as pioglitazone sulfate, and pharmaceutical compositions and processes using the same
BE1014453A6 (nl) Amlodipinefumaraat.
US4477458A (en) Thiazolidine derivatives and their mucolytic compositions and methods
CA2433190C (en) Amlodipine hemimaleate
CA2372238C (en) Polymorphs of a crystalline azabicyclo (2,2,2) octan-3-amine citrate and their pharmaceutical compositions
JP2006500320A (ja) カルベジロール一クエン酸塩一水和物
WO2005021481A1 (en) N, n’-dibenzyl ethylenediamine salt pf 2-(alpha-hidroxypentyl) benzoic acid and its preparing process and usage
DK200300114U3 (da) Faste tilstandsformer af ondansetron
BG62228B2 (bg) Безводна кристална натриева сол на 5-хлор-3-(2-теноил)-2- оксиндол-1-карбоксамид
HU211140A9 (hu) Az 5-klór-3-(2*tenoil)-2-oxindol-1-karboxamid vízmentes, kristályos nátriumsója
CZ12566U1 (cs) Amlodipinhemimaleát a farmaceutický prostředek
HU204046B (en) Process for producing anhydrous, crystalline sodium salt of 5-chloro-3-(2-thenyl)-2-oxindole-1-carboxamide and pharmaceutical compositions comprising same
SI21067A2 (sl) Amlodipin hemimaleat
CZ12615U1 (cs) Směsná sůl amlodipinfumarátu, farmaceutický prostředek, a použití

Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees