PT86675A - Process for preparing an anhydrous crystalline sodium salt of 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamide - Google Patents

Process for preparing an anhydrous crystalline sodium salt of 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamide

Info

Publication number
PT86675A
PT86675A PT86675A PT8667588A PT86675A PT 86675 A PT86675 A PT 86675A PT 86675 A PT86675 A PT 86675A PT 8667588 A PT8667588 A PT 8667588A PT 86675 A PT86675 A PT 86675A
Authority
PT
Portugal
Prior art keywords
thenoyl
oxindole
carboxamide
chloro
preparing
Prior art date
Application number
PT86675A
Other languages
English (en)
Other versions
PT86675B (pt
Inventor
Douglas John Meldrum Allen
Brian Thomas O Neill
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT86675A publication Critical patent/PT86675A/pt
Publication of PT86675B publication Critical patent/PT86675B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT86675A 1987-02-02 1988-02-01 Processo para a preparacao de um sal de sodio cristalino e anidro de 5-cloro-3--(2-tenoil)-2-oxindole-1-carboxamida PT86675B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/000201 WO1988005656A1 (en) 1987-02-02 1987-02-02 Anhydrous, crystalline sodium salt of 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamide

Publications (2)

Publication Number Publication Date
PT86675A true PT86675A (pt) 1988-03-01
PT86675B PT86675B (pt) 1992-07-31

Family

ID=22202263

Family Applications (1)

Application Number Title Priority Date Filing Date
PT86675A PT86675B (pt) 1987-02-02 1988-02-01 Processo para a preparacao de um sal de sodio cristalino e anidro de 5-cloro-3--(2-tenoil)-2-oxindole-1-carboxamida

Country Status (42)

Country Link
US (1) US5036099A (pt)
EP (1) EP0277738B1 (pt)
JP (1) JPS63201184A (pt)
KR (1) KR900001422B1 (pt)
CN (1) CN1022324C (pt)
AP (1) AP52A (pt)
AR (1) AR243182A1 (pt)
AT (1) ATE73800T1 (pt)
AU (1) AU587736B2 (pt)
BG (1) BG51042A3 (pt)
CA (1) CA1335590C (pt)
CS (2) CS265250B2 (pt)
CY (1) CY1775A (pt)
DD (1) DD267490A5 (pt)
DE (1) DE3869149D1 (pt)
DK (1) DK44888A (pt)
EC (1) ECSP941082A (pt)
ES (1) ES2032955T3 (pt)
FI (1) FI89598C (pt)
GR (1) GR3004200T3 (pt)
HK (1) HK132695A (pt)
IE (1) IE60000B1 (pt)
IL (1) IL85277A (pt)
IN (1) IN171799B (pt)
IS (1) IS1533B (pt)
LV (1) LV10252B (pt)
MA (1) MA21171A1 (pt)
MY (1) MY102737A (pt)
NO (1) NO170581C (pt)
NZ (1) NZ223373A (pt)
OA (1) OA08710A (pt)
PH (1) PH26545A (pt)
PL (1) PL149550B1 (pt)
PT (1) PT86675B (pt)
RO (1) RO105052B1 (pt)
RU (1) RU2011381C1 (pt)
SG (1) SG27994G (pt)
SI (1) SI8810183A8 (pt)
UA (1) UA25898A1 (pt)
WO (1) WO1988005656A1 (pt)
YU (1) YU46766B (pt)
ZA (1) ZA88679B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853409A (en) * 1988-04-13 1989-08-01 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
US4861794A (en) * 1988-04-13 1989-08-29 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
HU208421B (en) * 1988-10-18 1993-10-28 Pfizer Process for producing starting materials for producing 3-acyl-2-oxindol-carboxamides ofantiphlogistic activity
DE68923673T2 (de) * 1988-10-18 1996-01-18 Pfizer Prodrogen von antiinflammatorischen 3-Acyl-2-oxindol-1-carboxamiden.
US5059693A (en) * 1989-10-06 1991-10-22 Pfizer Inc. Process for making 3-aroyl-2-oxindole-1-carboxamides
US5008283A (en) * 1990-03-19 1991-04-16 Pfizer Inc. Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
US5006547A (en) * 1990-03-19 1991-04-09 Pfizer Inc. Tenidap as an inhibitor of the release of elastase by neutrophils
US5122534A (en) * 1991-02-08 1992-06-16 Pfizer Inc. Use of tenidap to reduce total serum cholesterol, ldl cholesterol and triglycerides
DE4111305C2 (de) * 1991-04-08 1994-12-01 Mack Chem Pharm Pharmazeutische Zubereitung zur rektalen Applikation, die ein 2-Oxindol-l-carboxamid-derivat enthält
WO1997022605A1 (en) * 1995-12-19 1997-06-26 Pfizer Inc. Stable, long acting salts of indole derivatives for the treatment of joint diseases
EP0826685A1 (en) * 1996-08-21 1998-03-04 Pfizer Inc. Stable, long acting salts of carboxamides for the treatment of joint disease
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
US7407195B2 (en) * 2004-04-14 2008-08-05 William Berson Label for receiving indicia having variable spectral emissivity values
US7651031B2 (en) * 2004-10-25 2010-01-26 William Berson Systems and methods for reading indicium
US7621451B2 (en) * 2005-01-14 2009-11-24 William Berson Radio frequency identification labels and systems and methods for making the same
US7931413B2 (en) * 2005-01-14 2011-04-26 William Berson Printing system ribbon including print transferable circuitry and elements
US7619520B2 (en) * 2005-01-14 2009-11-17 William Berson Radio frequency identification labels and systems and methods for making the same
US7728726B2 (en) * 2005-01-14 2010-06-01 William Berson Radio frequency identification labels
US11653929B2 (en) 2017-11-02 2023-05-23 Accurate Medical Therapeutics Ltd. Embolization catheter with integral filter

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3767653A (en) * 1971-06-28 1973-10-23 Squibb & Sons Inc Thiazines
GB1532413A (en) * 1974-12-23 1978-11-15 Union International Co Ltd Chenodeoxycholic acid
DE2613346C3 (de) * 1976-03-29 1981-07-23 Diamalt AG, 8000 München Monoklin kristalline Chenodesoxycholsäure und Verfahren zu ihrer Herstellung
DE3582890D1 (de) * 1984-02-07 1991-06-20 Pfizer 2-oxindolzwischenprodukte.
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
PT80116B (pt) * 1984-03-19 1987-10-20 Pfizer Processo para a producao de 2-oxindole-1-carboxamidas e de intermediarios para esse efeito
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents

Also Published As

Publication number Publication date
EP0277738A1 (en) 1988-08-10
IN171799B (pt) 1993-01-09
AP8800081A0 (en) 1987-11-01
OA08710A (fr) 1989-03-31
CS354191A3 (en) 1992-04-15
CY1775A (en) 1996-04-05
CS64888A2 (en) 1988-08-16
JPS63201184A (ja) 1988-08-19
LV10252B (en) 1995-04-20
ZA88679B (en) 1989-09-27
IS1533B (is) 1994-01-28
CS265250B2 (en) 1989-10-13
AR243182A1 (es) 1993-07-30
UA25898A1 (uk) 1999-02-26
IE880269L (en) 1988-08-02
NO170581B (no) 1992-07-27
GR3004200T3 (pt) 1993-03-31
PL149550B1 (en) 1990-02-28
FI89598B (fi) 1993-07-15
WO1988005656A1 (en) 1988-08-11
KR900001422B1 (ko) 1990-03-09
CA1335590C (en) 1995-05-16
FI89598C (fi) 1993-10-25
DK44888A (da) 1988-08-03
ES2032955T3 (es) 1996-07-16
KR880009961A (ko) 1988-10-06
AU1116088A (en) 1988-08-04
US5036099A (en) 1991-07-30
CN88100555A (zh) 1988-08-17
YU18388A (en) 1989-10-31
NO884329D0 (no) 1988-09-29
AP52A (en) 1989-09-16
JPH0576945B2 (pt) 1993-10-25
PL270415A1 (en) 1988-12-08
NO170581C (no) 1992-11-04
CN1022324C (zh) 1993-10-06
ECSP941082A (es) 1994-12-15
IE60000B1 (en) 1994-05-18
DE3869149D1 (de) 1992-04-23
FI893647A0 (fi) 1989-08-01
NO884329L (no) 1988-09-29
IL85277A0 (en) 1988-07-31
PT86675B (pt) 1992-07-31
AU587736B2 (en) 1989-08-24
DK44888D0 (da) 1988-01-29
PH26545A (en) 1992-08-19
EP0277738B1 (en) 1992-03-18
RO105052B1 (en) 1994-12-01
SI8810183A8 (sl) 1996-08-31
RU2011381C1 (ru) 1994-04-30
MA21171A1 (fr) 1988-10-01
MY102737A (en) 1992-09-30
NZ223373A (en) 1989-06-28
IS3309A7 (is) 1988-08-03
IL85277A (en) 1994-02-27
ATE73800T1 (de) 1992-04-15
HK132695A (en) 1995-09-01
SG27994G (en) 1994-10-14
DD267490A5 (de) 1989-05-03
LV10252A (lv) 1994-10-20
YU46766B (sh) 1994-05-10
BG51042A3 (en) 1993-01-15

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920103

MM3A Annulment or lapse

Effective date: 20050704