IL64954A - 2-hydroxymethyl-3-hydroxy-pyridine derivatives useful as intermediates in the preparation of pirobuterol - Google Patents

2-hydroxymethyl-3-hydroxy-pyridine derivatives useful as intermediates in the preparation of pirobuterol

Info

Publication number
IL64954A
IL64954A IL64954A IL6495482A IL64954A IL 64954 A IL64954 A IL 64954A IL 64954 A IL64954 A IL 64954A IL 6495482 A IL6495482 A IL 6495482A IL 64954 A IL64954 A IL 64954A
Authority
IL
Israel
Prior art keywords
pirobuterol
hydroxymethyl
intermediates
hydroxy
preparation
Prior art date
Application number
IL64954A
Other languages
English (en)
Other versions
IL64954A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL64954A0 publication Critical patent/IL64954A0/xx
Publication of IL64954A publication Critical patent/IL64954A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Catalysts (AREA)
IL64954A 1981-02-09 1982-02-09 2-hydroxymethyl-3-hydroxy-pyridine derivatives useful as intermediates in the preparation of pirobuterol IL64954A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23292381A 1981-02-09 1981-02-09

Publications (2)

Publication Number Publication Date
IL64954A0 IL64954A0 (en) 1982-04-30
IL64954A true IL64954A (en) 1986-03-31

Family

ID=22875140

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64954A IL64954A (en) 1981-02-09 1982-02-09 2-hydroxymethyl-3-hydroxy-pyridine derivatives useful as intermediates in the preparation of pirobuterol

Country Status (26)

Country Link
EP (4) EP0058069B1 (ko)
JP (4) JPS57150665A (ko)
KR (1) KR860000623B1 (ko)
AR (4) AR231439A1 (ko)
AT (2) ATE20882T1 (ko)
AU (1) AU530826B2 (ko)
CA (1) CA1179677A (ko)
CS (1) CS229678B2 (ko)
DD (2) DD210034A5 (ko)
DE (2) DE3272793D1 (ko)
DK (1) DK157541C (ko)
EG (1) EG16242A (ko)
ES (4) ES8305721A1 (ko)
FI (1) FI820396L (ko)
GR (1) GR75867B (ko)
GT (1) GT198273686A (ko)
IE (2) IE52325B1 (ko)
IL (1) IL64954A (ko)
NO (4) NO820371L (ko)
NZ (1) NZ199646A (ko)
PH (4) PH20622A (ko)
PL (4) PL130678B1 (ko)
PT (1) PT74397B (ko)
SU (4) SU1194273A3 (ko)
YU (3) YU42756B (ko)
ZA (1) ZA82778B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3615293A1 (de) * 1986-05-06 1987-11-12 Bayer Ag Verwendung von heteroarylethylaminen zur leistungsfoerderung bei tieren, heteroarylethylamine und verfahren zu ihrer herstellung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700681A (en) * 1971-02-16 1972-10-24 Pfizer 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-aminoethyl)pyridines
BE795937A (fr) * 1972-03-01 1973-08-27 Pepro Procede d'hydroxymethylation d'une 3-hydroxy-pyridine substituee
AR207639A1 (es) * 1973-12-26 1976-10-22 Pfizer Un procedimiento para preparar pirido (3,2-d)1,3-dioxin-6-epoxietanos y compuestos intermediarios desprovistos de actividad terapeutica
US4031108A (en) * 1974-10-09 1977-06-21 Pfizer Inc. 2-Hydroxymethyl-3-benzyloxypyridine-6-epoxyethane
US3952101A (en) * 1975-04-14 1976-04-20 Smithkline Corporation α-Amino methyl-5-hydroxy-2-pyridinemethanols

Also Published As

Publication number Publication date
DK157541B (da) 1990-01-22
ES8403112A1 (es) 1984-03-01
JPS57150665A (en) 1982-09-17
EP0058069B1 (en) 1986-08-27
SU1240354A3 (ru) 1986-06-23
DK157541C (da) 1990-06-11
IE52325B1 (en) 1987-09-16
AR229374A1 (es) 1983-07-29
YU42756B (en) 1988-12-31
PL130678B1 (en) 1984-08-31
SU1250170A3 (ru) 1986-08-07
PL130918B1 (en) 1984-09-29
KR860000623B1 (ko) 1986-05-24
GR75867B (ko) 1984-08-02
ATE21691T1 (de) 1986-09-15
CS229678B2 (en) 1984-06-18
JPS6119624B2 (ko) 1986-05-17
YU26682A (en) 1985-04-30
PL130917B1 (en) 1984-09-29
EP0058071B1 (en) 1986-07-23
NZ199646A (en) 1985-11-08
EP0058070A2 (en) 1982-08-18
ATE20882T1 (de) 1986-08-15
JPS60208964A (ja) 1985-10-21
DD202544A5 (de) 1983-09-21
ES8403111A1 (es) 1984-03-01
AU530826B2 (en) 1983-07-28
CA1179677A (en) 1984-12-18
NO824273L (no) 1982-08-10
EP0058071A3 (en) 1982-08-25
JPS6193164A (ja) 1986-05-12
JPS60208962A (ja) 1985-10-21
KR830009028A (ko) 1983-12-17
PL235000A1 (en) 1983-04-11
ES8403110A1 (es) 1984-03-01
NO824274L (no) 1982-08-10
PL239427A1 (en) 1983-04-25
IE820275L (en) 1982-08-09
EP0058070A3 (en) 1982-08-25
PT74397B (en) 1984-10-09
YU42908B (en) 1988-12-31
YU43389B (en) 1989-06-30
DK52182A (da) 1982-09-17
EG16242A (en) 1989-01-30
YU201884A (en) 1985-04-30
AR229373A1 (es) 1983-07-29
EP0058069A2 (en) 1982-08-18
IL64954A0 (en) 1982-04-30
ES518972A0 (es) 1984-03-01
IE820273L (en) 1982-08-09
EP0058069A3 (en) 1982-09-01
AU8027182A (en) 1982-08-19
PH20622A (en) 1987-03-06
DD210034A5 (de) 1984-05-30
ZA82778B (en) 1983-01-26
IE52326B1 (en) 1987-09-16
JPS6059911B2 (ja) 1985-12-27
ES509430A0 (es) 1983-04-16
ES518971A0 (es) 1984-03-01
JPS6059231B2 (ja) 1985-12-24
PL130580B1 (en) 1984-08-31
FI820396L (fi) 1982-08-10
YU201984A (en) 1985-04-30
PH19164A (en) 1986-01-16
SU1194273A3 (ru) 1985-11-23
NO820371L (no) 1982-08-10
ES518973A0 (es) 1984-03-01
PH19167A (en) 1986-01-16
PL239426A1 (en) 1983-04-25
PT74397A (en) 1982-03-01
PH20292A (en) 1986-11-18
EP0058071A2 (en) 1982-08-18
PL239428A1 (en) 1983-04-25
GT198273686A (es) 1983-07-30
AR231439A1 (es) 1984-11-30
AR229712A1 (es) 1983-10-31
EP0058072A2 (en) 1982-08-18
ES8305721A1 (es) 1983-04-16
DE3272061D1 (en) 1986-08-28
NO824275L (no) 1982-08-10
EP0058072A3 (en) 1982-08-25
SU1217253A3 (ru) 1986-03-07
JPS6135184B2 (ko) 1986-08-12
DE3272793D1 (en) 1986-10-02

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Legal Events

Date Code Title Description
NE Application for restoration - patent lapsed through non-payment of renewal fees (section 60, patents law, 5727-1967)
NF Patent restored
KB Patent renewed