GB2107309B - Preparation of 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives - Google Patents

Preparation of 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives

Info

Publication number
GB2107309B
GB2107309B GB08223902A GB8223902A GB2107309B GB 2107309 B GB2107309 B GB 2107309B GB 08223902 A GB08223902 A GB 08223902A GB 8223902 A GB8223902 A GB 8223902A GB 2107309 B GB2107309 B GB 2107309B
Authority
GB
United Kingdom
Prior art keywords
halo
hydroxy
amino
preparation
pyrimidine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08223902A
Other versions
GB2107309A (en
Inventor
Andras Vedres
Judit Horvath
Laszlo Ladanyi
Tamas Mester
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of GB2107309A publication Critical patent/GB2107309A/en
Application granted granted Critical
Publication of GB2107309B publication Critical patent/GB2107309B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08223902A 1981-08-28 1982-08-19 Preparation of 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives Expired GB2107309B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU812482A HU187355B (en) 1981-08-28 1981-08-28 Process for preparing 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives

Publications (2)

Publication Number Publication Date
GB2107309A GB2107309A (en) 1983-04-27
GB2107309B true GB2107309B (en) 1985-05-30

Family

ID=10959594

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08223902A Expired GB2107309B (en) 1981-08-28 1982-08-19 Preparation of 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives

Country Status (10)

Country Link
JP (1) JPS5874671A (en)
BE (1) BE894193A (en)
CH (1) CH648833A5 (en)
ES (1) ES8306479A1 (en)
FI (1) FI822818L (en)
FR (1) FR2512021B1 (en)
GB (1) GB2107309B (en)
HU (1) HU187355B (en)
IT (1) IT1190971B (en)
SU (1) SU1132789A3 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495558B1 (en) 1999-01-22 2002-12-17 Amgen Inc. Kinase inhibitors
EP1144390A2 (en) * 1999-01-22 2001-10-17 Amgen Inc., Kinase inhibitors

Also Published As

Publication number Publication date
ES515190A0 (en) 1983-06-01
HU187355B (en) 1985-12-28
IT1190971B (en) 1988-02-24
IT8222986A0 (en) 1982-08-26
FI822818L (en) 1983-03-01
CH648833A5 (en) 1985-04-15
FR2512021A1 (en) 1983-03-04
FI822818A0 (en) 1982-08-12
JPS5874671A (en) 1983-05-06
GB2107309A (en) 1983-04-27
ES8306479A1 (en) 1983-06-01
SU1132789A3 (en) 1984-12-30
FR2512021B1 (en) 1985-08-09
BE894193A (en) 1983-02-25

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee