ES8403111A1 - Un procedimiento para la preparacion de pirbuterol. - Google Patents
Un procedimiento para la preparacion de pirbuterol.Info
- Publication number
- ES8403111A1 ES8403111A1 ES518972A ES518972A ES8403111A1 ES 8403111 A1 ES8403111 A1 ES 8403111A1 ES 518972 A ES518972 A ES 518972A ES 518972 A ES518972 A ES 518972A ES 8403111 A1 ES8403111 A1 ES 8403111A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- formula
- hydrogen
- hydroxymethyl
- chem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Catalysts (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE PIRBUTEROL, DE FORMULA GENERAL (I).CONSISTE EN CALENTAR UN PRIMER COMPUESTO DE FORMULA (II) EN ANHIDRIDO ACETICO PARA OBTENER UN SEGUNDO COMPUESTO DE FORMULA GENERAL (III), EN DONDE Y ES BENCILO O CH3CO. DICHO SEGUNDO COMPUESTO DE FORMULA (III)SE SOLVOLIZA E HIDROGENOLIZA PARA OBTENER EL PIRBUTEROL.DE APLICACION EN MEDICINA POR SU ACTIVIDAD BRONDILATADORA Y TAMBIEN EN EL TRATAMIENTO DEL FALLO CARDIACO CONGESTIVO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23292381A | 1981-02-09 | 1981-02-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES518972A0 ES518972A0 (es) | 1984-03-01 |
| ES8403111A1 true ES8403111A1 (es) | 1984-03-01 |
Family
ID=22875140
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509430A Granted ES509430A0 (es) | 1981-02-09 | 1982-02-08 | Un procedimiento para la preparacion de derivados del pirbuterol. |
| ES518972A Expired ES8403111A1 (es) | 1981-02-09 | 1983-01-13 | Un procedimiento para la preparacion de pirbuterol. |
| ES518973A Granted ES518973A0 (es) | 1981-02-09 | 1983-01-13 | Un procedimiento para la preparacion de un derivado del pirbuterol. |
| ES518971A Expired ES8403110A1 (es) | 1981-02-09 | 1983-01-13 | Un procedimiento para la preparacion de pirbuterol. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509430A Granted ES509430A0 (es) | 1981-02-09 | 1982-02-08 | Un procedimiento para la preparacion de derivados del pirbuterol. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES518973A Granted ES518973A0 (es) | 1981-02-09 | 1983-01-13 | Un procedimiento para la preparacion de un derivado del pirbuterol. |
| ES518971A Expired ES8403110A1 (es) | 1981-02-09 | 1983-01-13 | Un procedimiento para la preparacion de pirbuterol. |
Country Status (26)
| Country | Link |
|---|---|
| EP (4) | EP0058071B1 (es) |
| JP (4) | JPS57150665A (es) |
| KR (1) | KR860000623B1 (es) |
| AR (4) | AR231439A1 (es) |
| AT (2) | ATE21691T1 (es) |
| AU (1) | AU530826B2 (es) |
| CA (1) | CA1179677A (es) |
| CS (1) | CS229678B2 (es) |
| DD (2) | DD202544A5 (es) |
| DE (2) | DE3272793D1 (es) |
| DK (1) | DK157541C (es) |
| EG (1) | EG16242A (es) |
| ES (4) | ES509430A0 (es) |
| FI (1) | FI820396L (es) |
| GR (1) | GR75867B (es) |
| GT (1) | GT198273686A (es) |
| IE (2) | IE52326B1 (es) |
| IL (1) | IL64954A (es) |
| NO (4) | NO820371L (es) |
| NZ (1) | NZ199646A (es) |
| PH (4) | PH20622A (es) |
| PL (4) | PL130678B1 (es) |
| PT (1) | PT74397B (es) |
| SU (4) | SU1194273A3 (es) |
| YU (3) | YU42756B (es) |
| ZA (1) | ZA82778B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3615293A1 (de) * | 1986-05-06 | 1987-11-12 | Bayer Ag | Verwendung von heteroarylethylaminen zur leistungsfoerderung bei tieren, heteroarylethylamine und verfahren zu ihrer herstellung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3700681A (en) * | 1971-02-16 | 1972-10-24 | Pfizer | 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-aminoethyl)pyridines |
| BE795937A (fr) * | 1972-03-01 | 1973-08-27 | Pepro | Procede d'hydroxymethylation d'une 3-hydroxy-pyridine substituee |
| AR207639A1 (es) * | 1973-12-26 | 1976-10-22 | Pfizer | Un procedimiento para preparar pirido (3,2-d)1,3-dioxin-6-epoxietanos y compuestos intermediarios desprovistos de actividad terapeutica |
| US4031108A (en) * | 1974-10-09 | 1977-06-21 | Pfizer Inc. | 2-Hydroxymethyl-3-benzyloxypyridine-6-epoxyethane |
| US3952101A (en) * | 1975-04-14 | 1976-04-20 | Smithkline Corporation | α-Amino methyl-5-hydroxy-2-pyridinemethanols |
-
1982
- 1982-02-03 SU SU823392299A patent/SU1194273A3/ru active
- 1982-02-04 NZ NZ199646A patent/NZ199646A/en unknown
- 1982-02-04 CS CS82781A patent/CS229678B2/cs unknown
- 1982-02-05 AR AR288347A patent/AR231439A1/es active
- 1982-02-05 GR GR67223A patent/GR75867B/el unknown
- 1982-02-05 GT GT198273686A patent/GT198273686A/es unknown
- 1982-02-08 NO NO820371A patent/NO820371L/no unknown
- 1982-02-08 DE DE8282300602T patent/DE3272793D1/de not_active Expired
- 1982-02-08 EP EP82300604A patent/EP0058071B1/en not_active Expired
- 1982-02-08 EP EP82300605A patent/EP0058072A3/en not_active Withdrawn
- 1982-02-08 AU AU80271/82A patent/AU530826B2/en not_active Expired
- 1982-02-08 FI FI820396A patent/FI820396L/fi not_active Application Discontinuation
- 1982-02-08 IE IE275/82A patent/IE52326B1/en not_active IP Right Cessation
- 1982-02-08 JP JP57018693A patent/JPS57150665A/ja active Granted
- 1982-02-08 DE DE8282300604T patent/DE3272061D1/de not_active Expired
- 1982-02-08 AT AT82300602T patent/ATE21691T1/de active
- 1982-02-08 EP EP82300603A patent/EP0058070A3/en not_active Withdrawn
- 1982-02-08 AT AT82300604T patent/ATE20882T1/de active
- 1982-02-08 KR KR8200528A patent/KR860000623B1/ko active
- 1982-02-08 DD DD82237264A patent/DD202544A5/de not_active IP Right Cessation
- 1982-02-08 ES ES509430A patent/ES509430A0/es active Granted
- 1982-02-08 DK DK052182A patent/DK157541C/da not_active IP Right Cessation
- 1982-02-08 IE IE273/82A patent/IE52325B1/en not_active IP Right Cessation
- 1982-02-08 DD DD82253605A patent/DD210034A5/de unknown
- 1982-02-08 CA CA000395768A patent/CA1179677A/en not_active Expired
- 1982-02-08 YU YU266/82A patent/YU42756B/xx unknown
- 1982-02-08 EP EP82300602A patent/EP0058069B1/en not_active Expired
- 1982-02-08 ZA ZA82778A patent/ZA82778B/xx unknown
- 1982-02-08 PT PT74397A patent/PT74397B/pt unknown
- 1982-02-09 PL PL1982239426A patent/PL130678B1/pl unknown
- 1982-02-09 PL PL1982239428A patent/PL130918B1/pl unknown
- 1982-02-09 PL PL1982235000A patent/PL130580B1/pl unknown
- 1982-02-09 PL PL1982239427A patent/PL130917B1/pl unknown
- 1982-02-09 PH PH26843A patent/PH20622A/en unknown
- 1982-02-09 EG EG60/82A patent/EG16242A/xx active
- 1982-02-09 IL IL64954A patent/IL64954A/xx active IP Right Revival
- 1982-11-17 AR AR291327A patent/AR229373A1/es active
- 1982-11-17 AR AR291328A patent/AR229374A1/es active
- 1982-11-17 AR AR291329A patent/AR229712A1/es active
- 1982-12-20 NO NO824275A patent/NO824275L/no unknown
- 1982-12-20 NO NO824274A patent/NO824274L/no unknown
- 1982-12-20 NO NO824273A patent/NO824273L/no unknown
-
1983
- 1983-01-05 SU SU833535711A patent/SU1217253A3/ru active
- 1983-01-05 SU SU833534854A patent/SU1250170A3/ru active
- 1983-01-05 SU SU833534107A patent/SU1240354A3/ru active
- 1983-01-13 ES ES518972A patent/ES8403111A1/es not_active Expired
- 1983-01-13 ES ES518973A patent/ES518973A0/es active Granted
- 1983-01-13 ES ES518971A patent/ES8403110A1/es not_active Expired
- 1983-10-19 PH PH29713A patent/PH19167A/en unknown
- 1983-10-19 PH PH29712A patent/PH20292A/en unknown
- 1983-10-19 PH PH29714A patent/PH19164A/en unknown
-
1984
- 1984-11-28 YU YU2019/84A patent/YU42908B/xx unknown
- 1984-11-28 YU YU2018/84A patent/YU43389B/xx unknown
-
1985
- 1985-01-23 JP JP60010724A patent/JPS6059231B2/ja not_active Expired
- 1985-01-23 JP JP60010723A patent/JPS6059911B2/ja not_active Expired
- 1985-10-09 JP JP60225922A patent/JPS6193164A/ja active Granted
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20031129 |