EP0082023A3
(fr)
*
|
1981-12-16 |
1983-07-20 |
Sankyo Company Limited |
Dérivés de la thiénopyrimidine, leur préparation et leur application en médicine
|
JPS60146891A
(ja)
*
|
1984-01-05 |
1985-08-02 |
Mitsubishi Chem Ind Ltd |
〔2,3−d〕チエノピリミジン誘導体およびその塩
|
EP0221947B1
(fr)
*
|
1985-05-07 |
1990-11-28 |
ALKALOIDA VEGYéSZETI GYáR |
Derives de triazolyl-quinoline
|
US4670560A
(en)
*
|
1986-04-28 |
1987-06-02 |
Ortho Pharmaceutical Corporation |
Thienopyrimidine-2,4-dione derivatives and intermediates thereof
|
WO1989008113A1
(fr)
*
|
1988-03-02 |
1989-09-08 |
Yoshitomi Pharmaceutical Industries, Ltd. |
COMPOSES DE 3,4-DIHYDROTHIENO[2,3-d]PYRIMIDINE ET LEURS APPLICATIONS PHARMACOLOGIQUES
|
US5280026A
(en)
*
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
GB8912335D0
(en)
*
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
DE4008726A1
(de)
*
|
1990-03-19 |
1991-09-26 |
Basf Ag |
Thieno(2,3-d)pyrimidinderivate
|
EP0452002A3
(en)
*
|
1990-03-30 |
1992-02-26 |
Dowelanco |
Thienopyrimidine derivatives
|
US5869486A
(en)
*
|
1995-02-24 |
1999-02-09 |
Ono Pharmaceutical Co., Ltd. |
Fused pyrimidines and pyriazines as pharmaceutical compounds
|
ES2185750T3
(es)
*
|
1995-08-08 |
2003-05-01 |
Ono Pharmaceutical Co |
Derivados de acido hidroxamico utiles para la inhibicion gelatinasa.
|
DE19632423A1
(de)
*
|
1996-08-12 |
1998-02-19 |
Merck Patent Gmbh |
Thienopyrimidine
|
DE19650378A1
(de)
*
|
1996-12-05 |
1998-06-10 |
Basf Ag |
Neue Pyrimidylverbindungen als Pflanzenschutzmittel
|
WO1998027087A1
(fr)
*
|
1996-12-18 |
1998-06-25 |
Eli Lilly And Company |
Procede combinatoire de realisation d'echantillotheques de pyrimidines fondues
|
US20030162795A1
(en)
*
|
1998-10-22 |
2003-08-28 |
Pfizer Inc. |
Thienopyrimidine and thienopyridine derivatives useful as anticancer agents
|
US6133271A
(en)
*
|
1998-11-19 |
2000-10-17 |
Cell Pathways, Inc. |
Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives
|
US6608053B2
(en)
*
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
US6503914B1
(en)
*
|
2000-10-23 |
2003-01-07 |
Board Of Regents, The University Of Texas System |
Thienopyrimidine-based inhibitors of the Src family
|
CN101100472A
(zh)
*
|
2001-04-30 |
2008-01-09 |
美国拜尔公司 |
4-氨基-5,6-取代的噻吩并[2,3-d]嘧啶化合物及其应用
|
US6805491B2
(en)
*
|
2002-05-20 |
2004-10-19 |
Stratos International, Inc. |
Stub having an optical fiber
|
AR044743A1
(es)
*
|
2002-09-26 |
2005-10-05 |
Nihon Nohyaku Co Ltd |
Herbicida, metodo de emplearlo, derivados de tienopirimidina sustituida,compuestos intermediarios, y procedimientos que se utilizan para producirlos,
|
US7612078B2
(en)
*
|
2003-03-31 |
2009-11-03 |
Epix Delaware, Inc. |
Piperidinylamino-thieno[2,3-D] pyrimidine compounds
|
US20050222175A1
(en)
*
|
2004-03-31 |
2005-10-06 |
Dhanoa Dale S |
New piperidinylamino-thieno[2,3-D] pyrimidine compounds
|
BRPI0408988A
(pt)
*
|
2003-03-31 |
2006-03-28 |
Predix Pharmaceuticals Holding |
composto de piperidinilamino-tieno[2,3-d]pirimidina
|
GB0315950D0
(en)
|
2003-06-11 |
2003-08-13 |
Xention Discovery Ltd |
Compounds
|
US7488736B2
(en)
*
|
2004-05-17 |
2009-02-10 |
Epix Delaware, Inc. |
Thienopyridinone compounds and methods of treatment
|
GB0412467D0
(en)
*
|
2004-06-04 |
2004-07-07 |
Astrazeneca Ab |
Chemical compounds
|
GB0412986D0
(en)
|
2004-06-10 |
2004-07-14 |
Xention Discovery Ltd |
Compounds
|
US7601725B2
(en)
*
|
2004-07-16 |
2009-10-13 |
Sunesis Pharmaceuticals, Inc. |
Thienopyrimidines useful as Aurora kinase inhibitors
|
GB0420719D0
(en)
*
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
US7598265B2
(en)
*
|
2004-09-30 |
2009-10-06 |
Epix Delaware, Inc. |
Compositions and methods for treating CNS disorders
|
US7407966B2
(en)
*
|
2004-10-07 |
2008-08-05 |
Epix Delaware, Inc. |
Thienopyridinone compounds and methods of treatment
|
US7576211B2
(en)
*
|
2004-09-30 |
2009-08-18 |
Epix Delaware, Inc. |
Synthesis of thienopyridinone compounds and related intermediates
|
EP1806347A4
(fr)
*
|
2004-10-08 |
2009-07-01 |
Astellas Pharma Inc |
Dérivé polycyclique aromatique de pyrimidine
|
BRPI0516242B1
(pt)
*
|
2004-10-21 |
2014-10-07 |
Dow Agrosciences Llc |
Compostos tieno-pirimidina com atividade fungicida, bem como composição fungicida e método para o controle ou prevenção de ataque fúngico
|
GB0423653D0
(en)
*
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
US7576212B2
(en)
|
2004-12-09 |
2009-08-18 |
Xention Limited |
Thieno[2,3-B] pyridines as potassium channel inhibitors
|
US7576080B2
(en)
*
|
2004-12-23 |
2009-08-18 |
Memory Pharmaceuticals Corporation |
Certain thienopyrimidine derivatives as phosphodiesterase 10 inhibitors
|
AU2005336552B2
(en)
*
|
2005-09-23 |
2010-09-16 |
Equispharm Co., Ltd |
5,6-dimethylthieno(2,3-di) pyrimidine derivatives, the preparation method thereof and the pharmaceutical composition comprising the same for anti-virus
|
WO2007046809A1
(fr)
*
|
2005-10-21 |
2007-04-26 |
Dow Agrosciences Llc |
Composes de thieno-pyrimidine a activite fongicide
|
US7531482B2
(en)
*
|
2005-10-21 |
2009-05-12 |
Dow Agrosciences Llc |
Thieno-pyrimidine compounds having fungicidal activity
|
WO2007056215A2
(fr)
*
|
2005-11-02 |
2007-05-18 |
Cytovia, Inc. |
N-aryl-thienopyrimidin-4-amines et analogues en tant qu'activateurs de caspases et inducteurs d'apoptose et utilisation associee
|
US20070099941A1
(en)
*
|
2005-11-02 |
2007-05-03 |
Cytovia, Inc. |
N-arylalkyl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof
|
US20070213305A1
(en)
*
|
2005-11-02 |
2007-09-13 |
Cytovia, Inc. |
N-alkyl-N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof
|
GB0525164D0
(en)
|
2005-12-09 |
2006-01-18 |
Xention Discovery Ltd |
Compounds
|
TWI417095B
(zh)
|
2006-03-15 |
2013-12-01 |
Janssen Pharmaceuticals Inc |
1,4-二取代之3-氰基-吡啶酮衍生物及其作為mGluR2-受體之正向異位性調節劑之用途
|
CA2650303C
(fr)
|
2006-04-26 |
2015-03-24 |
F. Hoffmann-La Roche Ag |
Composes pharmaceutiques de thienopyrimidine et leur utilisation
|
WO2007127183A1
(fr)
|
2006-04-26 |
2007-11-08 |
Genentech, Inc. |
Composes inhibiteurs de phosphoinositide 3-kinase et compositions pharmaceutiques les contenant
|
EP2041139B1
(fr)
*
|
2006-04-26 |
2011-11-09 |
F. Hoffmann-La Roche AG |
Composés pharmaceutiques
|
EP2026656B1
(fr)
|
2006-05-22 |
2015-12-23 |
Merial, Inc. |
Methodes insecticides utilisant des composes de 4-amino-5-chloro-thieno[2,3-d]-pyrimidine
|
ZA200904531B
(en)
*
|
2006-12-07 |
2010-09-29 |
Hoffmann La Roche |
Phosphoinositide 3-kinase inhibitor compounds and methods of use
|
AR064155A1
(es)
*
|
2006-12-07 |
2009-03-18 |
Piramed Ltd |
Compuestos de inhibidores de fosfoinositido-3 quinasa y metodos de uso
|
TW200845978A
(en)
*
|
2007-03-07 |
2008-12-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
|
TW200900065A
(en)
|
2007-03-07 |
2009-01-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
|
US9603848B2
(en)
*
|
2007-06-08 |
2017-03-28 |
Senomyx, Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
US7928111B2
(en)
*
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
US8633186B2
(en)
|
2007-06-08 |
2014-01-21 |
Senomyx Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
ES2365966T3
(es)
|
2007-09-14 |
2011-10-14 |
Ortho-Mcneil-Janssen Pharmaceuticals, Inc. |
4-(aril-x-fenil)-1h-piridin-2-onas 1,3-disustituidas.
|
KR20100080597A
(ko)
*
|
2007-09-14 |
2010-07-09 |
오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 |
1,3-이치환된-4-페닐-1h-피리딘-2-온
|
RS51660B
(en)
*
|
2007-09-14 |
2011-10-31 |
Ortho-Mcneil-Janssen Pharmaceuticals Inc. |
1`, 3`-DISUPSTITUATED-4-PHENYL-3,4,5,6-TETRAHYDRO-2H, 1`H- [1,4`] BIPYRIDINYL-2`-ONE
|
WO2009055730A1
(fr)
|
2007-10-25 |
2009-04-30 |
Genentech, Inc. |
Procédé de préparation de composés de thiénopyrimidine
|
GB0721095D0
(en)
*
|
2007-10-26 |
2007-12-05 |
Piramed Ltd |
Pharmaceutical compounds
|
RU2492170C9
(ru)
*
|
2007-11-14 |
2013-12-27 |
Орто-Макнейл-Янссен Фармасьютикалз, Инк. |
Имидазо[1,2-а]пиридиновые производные и их применение в качестве положительных аллостерических модуляторов рецепторов mglur2
|
MX2011001155A
(es)
|
2008-07-31 |
2011-07-29 |
Senomyx Inc |
Composiciones que comprenden mejoradores del dulzor, y métodos para prepararlas.
|
UA117296C2
(uk)
|
2008-07-31 |
2018-07-10 |
Сіномікс, Інк. |
Способи і проміжні сполуки для одержання підсилювачів солодкого смаку
|
RU2510396C2
(ru)
|
2008-09-02 |
2014-03-27 |
Янссен Фармасьютикалз, Инк. |
3-азабицикло[3.1.0]гексильные производные в качестве модуляторов метаботропных глутаматных рецепторов
|
US8697689B2
(en)
|
2008-10-16 |
2014-04-15 |
Janssen Pharmaceuticals, Inc. |
Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
|
CN102232074B
(zh)
|
2008-11-28 |
2014-12-03 |
奥梅-杨森制药有限公司 |
作为代谢性谷氨酸盐受体调节剂的吲哚和苯并噁嗪衍生物
|
WO2010065743A2
(fr)
*
|
2008-12-03 |
2010-06-10 |
Nanotherapeutics, Inc. |
Composés bicycliques et leurs procédés de fabrication et d'utilisation
|
MY153913A
(en)
|
2009-05-12 |
2015-04-15 |
Janssen Pharmaceuticals Inc |
7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
KR101753826B1
(ko)
|
2009-05-12 |
2017-07-04 |
얀센 파마슈티칼즈, 인코포레이티드 |
1,2,4―트리아졸로[4,3―a]피리딘 유도체 및 신경정신 질환의 치료 또는 예방을 위한 이들의 용도
|
US8946205B2
(en)
|
2009-05-12 |
2015-02-03 |
Janssen Pharmaceuticals, Inc. |
1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
|
JP5781066B2
(ja)
*
|
2009-05-27 |
2015-09-16 |
ジェネンテック, インコーポレイテッド |
p110δに対して選択的な二環式ピリミジンPI3K阻害剤化合物及び使用方法
|
CA2772371A1
(fr)
*
|
2009-05-27 |
2010-12-02 |
F. Hoffmann-La Roche Ag |
Composes bicycliques indole-pyrimidine inhibiteurs de pi3k selectifs pour p110 delta et leurs procedes d'utilisation
|
EP2455371B1
(fr)
*
|
2009-07-16 |
2013-12-25 |
SDS Biotech K. K. |
Dérivés de 4-(3-butynyl)aminopyrimidine comme agents pesticides pour un usage agricole et horticole
|
US9133209B2
(en)
*
|
2009-07-30 |
2015-09-15 |
Merial, Inc. |
Insecticidal 4-amino-thieno[2,3-D]-pyrimidine compounds and methods of their use
|
RU2563193C2
(ru)
*
|
2009-10-12 |
2015-09-20 |
Ф.Хоффманн-Ля Рош Аг |
Комбинации ингибитора pi3k и ингибитора мек
|
CA2808432C
(fr)
*
|
2010-07-23 |
2019-06-04 |
President And Fellows Of Harvard College |
Composes ameliorant l'activite de proteasome tricyclique au moyen d'une ame thieno[2,3-d]pyrimidine
|
BR112013003332B1
(pt)
|
2010-08-12 |
2018-11-13 |
Senomyx, Inc. |
método para melhorar a estabilidade de intensificador de doce e composição contendo intensificador de doce estabilizado
|
AU2011328203B2
(en)
|
2010-11-08 |
2015-03-19 |
Janssen Pharmaceuticals, Inc. |
1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
|
EP2649069B1
(fr)
|
2010-11-08 |
2015-08-26 |
Janssen Pharmaceuticals, Inc. |
Dérivés de 1,2,4-triazolo[4,3-a]pyridine et leur utilisation en tant que modulateurs allostériques positifs des récepteurs mglur2
|
JP5852665B2
(ja)
|
2010-11-08 |
2016-02-03 |
ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド |
1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
|
UA109688C2
(xx)
|
2010-12-16 |
2015-09-25 |
|
Трициклічні інгібітори pі3k та їх застосування
|
NZ613449A
(en)
*
|
2011-01-14 |
2015-08-28 |
Sds Biotech Corp |
Agri-horticultural pest control compositions comprising 4-(3-butynyl)aminopyrimidine derivatives
|
MX2013008822A
(es)
*
|
2011-02-09 |
2013-10-07 |
Hoffmann La Roche |
Compuestos heterociclicos como inhibidores de cinasa fosfatidilinositol-3 (pi3).
|
EP2734530A1
(fr)
|
2011-07-19 |
2014-05-28 |
Infinity Pharmaceuticals, Inc. |
Composés hétérocycliques et leurs utilisations
|
KR20150041040A
(ko)
|
2012-08-06 |
2015-04-15 |
세노믹스, 인코포레이티드 |
단맛 향미 개질제
|
JO3155B1
(ar)
|
2013-02-19 |
2017-09-20 |
Senomyx Inc |
معدِّل نكهة حلوة
|
JO3368B1
(ar)
|
2013-06-04 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
|
JO3367B1
(ar)
|
2013-09-06 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
|
NZ722385A
(en)
|
2014-01-21 |
2019-11-29 |
Janssen Pharmaceutica Nv |
Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
|
UA127921C2
(uk)
|
2014-01-21 |
2024-02-14 |
Янссен Фармацевтика Нв |
Комбінації, які містять позитивні алостеричні модулятори або ортостеричні агоністи метаботропного глутаматергічного рецептора 2 підтипу, та їх застосування
|
CN104725398B
(zh)
*
|
2015-01-29 |
2017-01-18 |
杨威 |
一种jak/stat3磷酸化抑制剂及其制备方法与用途
|
WO2017019537A1
(fr)
*
|
2015-07-24 |
2017-02-02 |
University Of Louisville Research Foundation, Inc. |
Composés, compositions, procédés pour le traitement de maladies et procédés pour la préparation de composés
|
US20220117968A1
(en)
*
|
2017-07-17 |
2022-04-21 |
Saint Louis University |
Thieno[2,3-d)pyrimidines and benzofuro(3,2-d)pyrimidines as antimicrobial agents
|
EP3814344B1
(fr)
|
2018-08-07 |
2024-07-24 |
Firmenich Incorporated |
4-amino-1 h-benzo[c][1,2,6] thiadiazine 2,2-dioxydes 5-substitués et formulations et utilisations de ceux-ci
|