IL243205A - Method for using gene expression to determine prognosis of prostate cancer - Google Patents

Method for using gene expression to determine prognosis of prostate cancer

Info

Publication number
IL243205A
IL243205A IL243205A IL24320515A IL243205A IL 243205 A IL243205 A IL 243205A IL 243205 A IL243205 A IL 243205A IL 24320515 A IL24320515 A IL 24320515A IL 243205 A IL243205 A IL 243205A
Authority
IL
Israel
Prior art keywords
hsa
mir
gene
expression
expression level
Prior art date
Application number
IL243205A
Other languages
English (en)
Hebrew (he)
Original Assignee
Genomic Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomic Health Inc filed Critical Genomic Health Inc
Publication of IL243205A publication Critical patent/IL243205A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL243205A 2010-07-27 2011-07-25 Method for using gene expression to determine prognosis of prostate cancer IL243205A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US36821710P 2010-07-27 2010-07-27
US41431010P 2010-11-16 2010-11-16
US201161485536P 2011-05-12 2011-05-12
PCT/US2011/045253 WO2012015765A2 (en) 2010-07-27 2011-07-25 Method for using gene expression to determine prognosis of prostate cancer

Publications (1)

Publication Number Publication Date
IL243205A true IL243205A (en) 2017-04-30

Family

ID=45527113

Family Applications (5)

Application Number Title Priority Date Filing Date
IL243205A IL243205A (en) 2010-07-27 2011-07-25 Method for using gene expression to determine prognosis of prostate cancer
IL243206A IL243206A (en) 2010-07-27 2011-07-25 A method for using gene expression to determine prostate cancer prognosis
IL243203A IL243203A (en) 2010-07-27 2011-07-25 Method for using gene expression to determine prognosis of prostate cancer
IL243201A IL243201A (en) 2010-07-27 2011-07-25 A method for using gene expression to determine prostate cancer prognosis
IL251403A IL251403B (en) 2010-07-27 2017-03-27 A method for using gene expression to determine the prognosis of prostate gland cancer

Family Applications After (4)

Application Number Title Priority Date Filing Date
IL243206A IL243206A (en) 2010-07-27 2011-07-25 A method for using gene expression to determine prostate cancer prognosis
IL243203A IL243203A (en) 2010-07-27 2011-07-25 Method for using gene expression to determine prognosis of prostate cancer
IL243201A IL243201A (en) 2010-07-27 2011-07-25 A method for using gene expression to determine prostate cancer prognosis
IL251403A IL251403B (en) 2010-07-27 2017-03-27 A method for using gene expression to determine the prognosis of prostate gland cancer

Country Status (12)

Country Link
US (6) US20120028264A1 (cg-RX-API-DMAC7.html)
EP (5) EP4083233A3 (cg-RX-API-DMAC7.html)
JP (5) JP2013532482A (cg-RX-API-DMAC7.html)
AU (1) AU2011282892B2 (cg-RX-API-DMAC7.html)
CA (2) CA2804626C (cg-RX-API-DMAC7.html)
DK (3) DK2598659T3 (cg-RX-API-DMAC7.html)
ES (4) ES2611000T3 (cg-RX-API-DMAC7.html)
IL (5) IL243205A (cg-RX-API-DMAC7.html)
MX (4) MX338883B (cg-RX-API-DMAC7.html)
NZ (1) NZ607282A (cg-RX-API-DMAC7.html)
SG (3) SG186940A1 (cg-RX-API-DMAC7.html)
WO (1) WO2012015765A2 (cg-RX-API-DMAC7.html)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2155897A2 (en) * 2007-03-30 2010-02-24 Source Precision Medicine, Inc. d/b/a Source MDX. Gene expression profiling for identification, monitoring, and treatment of prostate cancer
US20120041274A1 (en) 2010-01-07 2012-02-16 Myriad Genetics, Incorporated Cancer biomarkers
EP3812469A1 (en) 2010-07-07 2021-04-28 Myriad Genetics, Inc. Gene signatures for cancer prognosis
SG186940A1 (en) 2010-07-27 2013-02-28 Genomic Health Inc Method for using gene expression to determine prognosis of prostate cancer
US9605319B2 (en) 2010-08-30 2017-03-28 Myriad Genetics, Inc. Gene signatures for cancer diagnosis and prognosis
HK1201881A1 (en) 2012-01-31 2015-09-11 Genomic Health, Inc. Gene expression profile algorithm and test for determining prognosis of prostate cancer
TW201343920A (zh) * 2012-03-29 2013-11-01 Nat Health Research Institutes 預測前列腺癌預後之分子標記、方法與套組
BR102012007246A2 (pt) * 2012-03-30 2016-02-10 Fundação Antonio Prudente métodos para prognóstico e classificação de resultados de um evento
WO2013155371A1 (en) * 2012-04-12 2013-10-17 Cornell University MiRNA-31 AS A DIAGNOSTIC, PROGNOSTIC AND THERAPEUTIC AGENT IN CANCER
GB201207722D0 (en) 2012-05-02 2012-06-13 Bergenbio As Method
EP2875157A4 (en) * 2012-07-20 2016-10-26 Diagnocure Inc METHOD, KITS AND COMPOSITIONS FOR THE CLINICAL EVALUATION OF PROSTATE CANCER
CN102816862A (zh) * 2012-09-19 2012-12-12 南开大学 miRNA 222在前列腺癌血清学诊断试剂盒中的应用
WO2014071226A1 (en) * 2012-11-02 2014-05-08 The Regents Of The University Of California Methods and systems for determining a likelihood of adverse prostate cancer pathology
CA2891653A1 (en) 2012-11-16 2014-05-22 Myriad Genetics, Inc. Gene signatures for cancer prognosis
GB201322034D0 (en) 2013-12-12 2014-01-29 Almac Diagnostics Ltd Prostate cancer classification
JP2017509351A (ja) * 2013-12-30 2017-04-06 ザ ヘンリー エム． ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド 前立腺癌遺伝子プロファイル及びその使用方法
JP6666852B2 (ja) 2014-01-16 2020-03-18 イルミナ インコーポレイテッド 前立腺がん再発の予後に関する遺伝子発現パネル
EP3143160B1 (en) 2014-05-13 2019-11-06 Myriad Genetics, Inc. Gene signatures for cancer prognosis
US10822661B2 (en) 2014-09-04 2020-11-03 Miodx Method of multivariate molecule analysis
US10480033B2 (en) 2015-01-14 2019-11-19 Ohio State Innovation Foundation MiRNA-based predictive models for diagnosis and prognosis of prostate cancer
CA2976577C (en) 2015-02-11 2024-11-19 Aarhus Universitet MICRORNA-BASED METHOD FOR THE EARLY DETECTION OF PROSTATE CANCER IN URINE SAMPLES
EP3262186B1 (en) 2015-02-27 2019-04-03 QIAGEN GmbH A microrna-based method for assessing the prognosis of a prostate cancer patient
CN104880565A (zh) * 2015-05-04 2015-09-02 贵州省人民医院 Zfp36前列腺癌预后诊断的检测试剂及其试剂盒
JP6743056B2 (ja) * 2015-05-29 2020-08-19 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 前立腺がん予後判定の方法
US20170107580A1 (en) 2015-10-15 2017-04-20 Dendreon Pharmaceuticals, Inc. Gene expression markers for predicting overall survival in subjects treated with sipuleucel-t
WO2017127696A1 (en) 2016-01-20 2017-07-27 Dana-Farber Cancer Institute, Inc. Compositions and methods for screening and identifying clinically aggressive prostate cancer
CN109072309B (zh) 2016-02-02 2023-05-16 夸登特健康公司 癌症进化检测和诊断
WO2017210662A1 (en) * 2016-06-03 2017-12-07 Castle Biosciences, Inc. Methods for predicting risk of recurrence and/or metastasis in soft tissue sarcoma
US10724089B2 (en) 2016-10-06 2020-07-28 The Board Of Trustees Of The University Of Illinois Spatial molecular analysis of tissue
WO2018098241A1 (en) * 2016-11-22 2018-05-31 University Of Rochester Methods of assessing risk of recurrent prostate cancer
GB201619808D0 (en) * 2016-11-23 2017-01-04 Univ London Queen Mary Biomarkers for the prognosis and diagnosis of cancer
CA3089406A1 (en) * 2018-01-25 2019-08-01 Sorbonne Universite Molecular signature and use thereof for the identification of indolent prostate cancer
PL3755816T3 (pl) 2018-02-22 2025-06-30 Liquid Biopsy Research LLC Sposoby wykrywania i leczenia nowotworu gruczołu krokowego
WO2020214718A1 (en) * 2019-04-16 2020-10-22 Memorial Sloan Kettering Cancer Center Rrm2 signature genes as prognostic markers in prostate cancer patients
JP2020195314A (ja) * 2019-05-31 2020-12-10 医薬資源研究所株式会社 疾患・体質の分析方法、疾患・体質の分析システム、プログラムおよびコンピュータ読み取り可能な記録媒体
CA3145375A1 (en) * 2019-07-05 2021-01-14 Intellexon Gmbh Determining individual hla patterns, use as prognosticators, target genes and therapeutic agents
WO2021124455A1 (ja) * 2019-12-17 2021-06-24 株式会社 東芝 分析方法及びキット
EP4077667A1 (en) * 2019-12-19 2022-10-26 F. Hoffmann-La Roche AG Use of sept9 inhibitors for treating hepatitis b virus infection
CN115038969A (zh) * 2020-01-30 2022-09-09 阿罗塞尔公司 预测患者生存
EP3885453A1 (en) * 2020-03-23 2021-09-29 Koninklijke Philips N.V. Prediction of radiotherapy response for prostate cancer subject based on dna repair genes
US11845993B2 (en) * 2020-03-24 2023-12-19 The Regents Of The University Of Michigan Methods for identifying prostate cancer
WO2022020756A1 (en) * 2020-07-23 2022-01-27 John Mansell Compositions and methods for treating pain and anxiety disorders
ES1277194Y (es) 2021-03-25 2021-11-26 Keyzell Holding Sl Sistema basado en inteligencia artificial para analizar biomarcadores y personalizar tratamientos para cáncer
EP4660323A1 (en) 2023-01-30 2025-12-10 Jichi Medical University Prognosis prediction method for metastatic hormone-sensitive prostate cancer
CN116640734B (zh) * 2023-06-17 2025-01-24 青岛农业大学 关键基因在体外调控卵母细胞gvbd的用途及干扰片段

Family Cites Families (170)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997000449A1 (en) 1995-06-14 1997-01-03 Aberdeen University Prognostic and therapeutic system for cancer
US6300060B1 (en) 1995-11-09 2001-10-09 Dana-Farber Cancer Institute, Inc. Method for predicting the risk of prostate cancer morbidity and mortality
USRE38490E1 (en) 1995-11-16 2004-04-06 Baylor College Of Medicine Method for identifying metastatic sequences
US5712097A (en) 1996-01-19 1998-01-27 The Johns Hopkins University School Of Medicine Tumor suppressor gene, DPC4
DE69734249T2 (de) 1996-07-15 2006-07-13 Mayo Foundation For Medical Education And Research, Rochester Verfahren zur detektion der hk2 polypeptide
US6479263B1 (en) 1996-11-14 2002-11-12 Baylor College Of Medicine Method for detection of micrometastatic prostate cancer
US6190857B1 (en) 1997-03-24 2001-02-20 Urocor, Inc. Diagnosis of disease state using MRNA profiles in peripheral leukocytes
AU8403098A (en) 1997-07-15 1999-02-10 Deaconess Hospital Reagents and methods for diagnosis and prognosis of proliferative disor ders
US20020165143A1 (en) 1997-12-03 2002-11-07 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
FI980488A7 (fi) 1998-03-04 1999-09-05 Arctic Partners Oy Ab Uusi diagnostinen menetelmä
GB2339200B (en) 1998-06-06 2001-09-12 Genostic Pharma Ltd Genostics
WO1999064627A2 (en) 1998-06-06 1999-12-16 Genostic Pharma Limited Probes used for genetic profiling
US6902892B1 (en) 1998-10-19 2005-06-07 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
AU1853600A (en) 1999-01-06 2000-07-24 Choong-Chin Liew Method for the detection of gene transcripts in blood and uses thereof
JP4495349B2 (ja) 1999-01-28 2010-07-07 ジェン−プローブ・インコーポレーテッド 癌の遺伝マーカーを生物学的サンプルにおいて検出するための核酸配列
US20030207808A1 (en) 1999-02-18 2003-11-06 Kinneret Savitzky Novel nucleic acid and amino acid sequences
FI990382A0 (fi) * 1999-02-23 1999-02-23 Arctic Partners Oy Ab Uusi diagnostinen menetelmä
WO2000061744A1 (fr) 1999-04-09 2000-10-19 Chugai Research Institute For Molecular Medicine, Inc. Nouveaux genes de foetus
US6960439B2 (en) 1999-06-28 2005-11-01 Source Precision Medicine, Inc. Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
US6692916B2 (en) 1999-06-28 2004-02-17 Source Precision Medicine, Inc. Systems and methods for characterizing a biological condition or agent using precision gene expression profiles
GB9926805D0 (en) 1999-11-13 2000-01-12 Zeneca Ltd Diagnostic methods
DK1246917T3 (da) * 2000-01-13 2009-06-08 Genentech Inc Humane Stra6-polypeptider
US6448086B1 (en) 2000-01-18 2002-09-10 Diagnostic Systems Laboratories, Inc. Insulin-like growth factor system and cancer
US6566130B1 (en) 2000-01-28 2003-05-20 Henry M. Jackson Foundation For The Advancement Of Military Medicine Androgen-regulated gene expressed in prostate tissue
US7700359B2 (en) 2000-06-02 2010-04-20 Novartis Vaccines And Diagnostics, Inc. Gene products differentially expressed in cancerous cells
AU2002214576A1 (en) 2000-10-13 2002-04-22 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Genes related to development of refractory prostate cancer
AU2002216009A1 (en) 2000-11-03 2002-05-15 Michael Giesing Clinical and functional validation of targets from disseminated cancer cells
US20030087818A1 (en) 2001-02-02 2003-05-08 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
CA2442820A1 (en) 2001-03-29 2002-10-10 Van Andel Institute Microarray gene expression profiling in clear cell renal cell carcinoma: prognosis and drug target identification
CA2448355A1 (en) 2001-05-25 2002-12-05 Mount Sinai Hospital Method of detecting and monitoring prostate and ovarian cancers
CA2450379A1 (en) 2001-06-10 2002-12-19 Irm Llc Molecular signatures of commonly fatal carcinomas
WO2003009814A2 (en) 2001-07-25 2003-02-06 Millennium Pharmaceuticals, Inc. Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer
US7229774B2 (en) 2001-08-02 2007-06-12 Regents Of The University Of Michigan Expression profile of prostate cancer
US7700293B2 (en) 2001-08-02 2010-04-20 The Regents Of The University Of Michigan Expression profile of prostate cancer
US20100297657A1 (en) 2001-08-02 2010-11-25 The Regents Of The University Of Michigan Expression profile of prostate cancer
CN102402650A (zh) 2001-11-09 2012-04-04 生命技术公司 利用基因表达分布图识别、监控和治疗疾病以及鉴定生物学状态
AU2002357747A1 (en) 2001-12-10 2003-06-23 Millennium Pharmaceuticals Inc. Novel genes encoding colon cancer antigens
US6949342B2 (en) 2001-12-21 2005-09-27 Whitehead Institute For Biomedical Research Prostate cancer diagnosis and outcome prediction by expression analysis
US20030215835A1 (en) 2002-01-15 2003-11-20 Zairen Sun Differentially-regulated prostate cancer genes
WO2003076610A2 (fr) * 2002-03-14 2003-09-18 Exonhit Therapeutics Sa Variants de kallikrein-2 et kallikrein-3 humaines et leurs utilisations
AUPS187002A0 (en) * 2002-04-22 2002-05-30 Queensland University Of Technology Condition-specific molecules and uses therefor
US20040053317A1 (en) 2002-09-10 2004-03-18 Sidney Kimmel Cancer Center Gene segregation and biological sample classification methods
WO2004028346A2 (en) 2002-09-25 2004-04-08 Amersham Biosciences (Sv) Corp. Detection methods
AU2003302777A1 (en) 2002-12-05 2004-06-30 Regulome Corporation Profiled regulatory sites useful for gene control
JP4824540B2 (ja) 2003-02-07 2011-11-30 ダイアノキュアー インク． サンプル中の前立腺癌を検出する方法
WO2004077942A2 (en) 2003-02-28 2004-09-16 Genpath Pharmaceuticals, Incorporated Inducible prostate cancer model
CA2522299A1 (en) 2003-04-15 2004-10-28 Avalon Pharmaceuticals, Inc Determining cancer-linked genes and therapeutic targets using molecular cytogenetic methods
US7659062B2 (en) * 2003-06-03 2010-02-09 The Board of Trustee of the University of Arkansas System Gene expression profiling of uterine serous papillary carcinomas and ovarian serous papillary tumors
PL3470535T3 (pl) 2003-06-24 2020-08-24 Genomic Health, Inc. Prognozowanie prawdopodobieństwa ponownego wystąpienia raka
EP3330875B1 (en) * 2003-07-10 2021-12-01 Genomic Health, Inc. Expression profile algorithm and test for prognosing breast cancer recurrence
US20070048738A1 (en) 2003-07-14 2007-03-01 Mayo Foundation For Medical Education And Research Methods and compositions for diagnosis, staging and prognosis of prostate cancer
AU2004262369A1 (en) 2003-07-29 2005-02-10 Bristol-Myers Squibb Company Biomarkers of cyclin-dependent kinase modulation
AU2004298604B2 (en) 2003-12-15 2010-09-23 The Regents Of The University Of California Molecular signature of the PTEN tumor suppressor
KR20070052694A (ko) 2004-01-09 2007-05-22 더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 유전자 발현을 위한 세포-유형-특이적 패턴
GB0400976D0 (en) 2004-01-16 2004-02-18 Univ Cambridge Tech Methods of diagnosis
WO2005076005A2 (en) 2004-01-30 2005-08-18 Medizinische Universität Wien A method for classifying a tumor cell sample based upon differential expression of at least two genes
JP2005211023A (ja) 2004-01-30 2005-08-11 Hayashibara Biochem Lab Inc 腎細胞癌の転移若しくは再発の可能性を予測する方法
WO2005083128A2 (en) 2004-02-25 2005-09-09 University Of South Florida Methods for predicting cancer outcome and gene signatures for use therein
EP2163650B1 (en) 2004-04-09 2015-08-05 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
US20070224596A1 (en) 2004-04-09 2007-09-27 Mariana Nacht Compositions and methods for the modifying hypoxia induced gene regulation
DE602004012330T2 (de) 2004-04-29 2009-03-19 Marc Ramael Verfahren und kit zum nachweis von bestandteilen in einer probe
CA2992180C (en) 2004-05-07 2021-02-23 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Methods of diagnosing or treating prostate cancer using the erg gene, alone or in combination with other over or under expressed genes in prostate cancer
JP2008500057A (ja) 2004-05-27 2008-01-10 バーテックス　ファーマシューティカルズ　インコーポレイテッド Ｉｍｐｄｈ経路の阻害をモニタリングするためのバイオマーカー
WO2005119260A2 (en) 2004-06-03 2005-12-15 Bayer Healthcare Ag Methods for predicting and monitoring response to cancer therapy
WO2006005043A2 (en) 2004-06-30 2006-01-12 Cemines, Inc. Compositions and methods for detecting protein interactions with target dna sequences
US7587279B2 (en) 2004-07-06 2009-09-08 Genomic Health Method for quantitative PCR data analysis system (QDAS)
EP1784511A4 (en) 2004-08-13 2009-03-11 Millennium Pharm Inc GENES, COMPOSITIONS, KITS AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF PROSTATE CANCER
US7572640B2 (en) 2004-09-28 2009-08-11 Singulex, Inc. Method for highly sensitive detection of single protein molecules labeled with fluorescent moieties
PL1836629T3 (pl) * 2004-11-05 2020-06-15 Genomic Health, Inc. Przewidywanie odpowiedzi na chemioterapię z zastosowaniem markerów ekspresji genu
AU2005308594A1 (en) 2004-11-24 2006-06-01 St George's Enterprises Limited Diagnosis of prostate cancer
EP1836313A4 (en) 2004-12-17 2010-06-30 Veridex Llc METHOD FOR ASSESSING PATIENTS WITH AKUTER MYELOIDER LEUKEMIA
US7943306B2 (en) 2005-01-12 2011-05-17 The Board Of Trustees Of The Leland Stanford Junior University Gene expression signature for prediction of human cancer progression
EP1855727A2 (en) 2005-02-17 2007-11-21 Dana-Farber Cancer Institute, Inc. Compositions, kits and methods for identification, assessment, prevention and therapy of cancer
WO2006091776A2 (en) * 2005-02-25 2006-08-31 The Brigham And Women's Hospital, Inc. Biomarkers for predicting prostate cancer progression
US8349555B2 (en) * 2005-03-16 2013-01-08 Gennadi V. Glinsky Methods and compositions for predicting death from cancer and prostate cancer survival using gene expression signatures
WO2006105642A1 (en) 2005-04-05 2006-10-12 British Columbia Cancer Agency Biomarkers for the detection of lung cancer and uses thereof
WO2006113678A2 (en) 2005-04-15 2006-10-26 Oncomethylome Sciences, Inc. Methylation markers for diagnosis and treatment of cancers
EP1910564A1 (en) 2005-05-13 2008-04-16 Duke University Gene expression signatures for oncogenic pathway deregulation
US20080275652A1 (en) 2005-05-13 2008-11-06 Universite Libre De Bruxelles Gene-based algorithmic cancer prognosis
US20060292610A1 (en) 2005-06-06 2006-12-28 Regents Of The University Of Michigan Prognostic meta signatures and uses thereof
ES2624863T3 (es) 2005-06-08 2017-07-17 Millennium Pharmaceuticals, Inc. Métodos para identificación, evaluación, y tratamiento de pacientes con terapia de cáncer
AU2006259583A1 (en) 2005-06-13 2006-12-28 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20070099209A1 (en) 2005-06-13 2007-05-03 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
CA2814598A1 (en) * 2005-09-12 2007-03-22 The Regents Of The University Of Michigan Recurrent gene fusions in prostate cancer
JP2009514555A (ja) 2005-11-08 2009-04-09 ユークリッド ダイアグノスティックス リミテッド ライアビリティー カンパニー 癌評価の遺伝子関連ＣｐＧアイランドのメチル化アッセイのための材料と方法
WO2007072225A2 (en) 2005-12-01 2007-06-28 Medical Prognosis Institute Methods and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
US8445198B2 (en) 2005-12-01 2013-05-21 Medical Prognosis Institute Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy
KR20080080525A (ko) 2005-12-08 2008-09-04 노파르티스 아게 유전자 전사에 대한 ｆｇｆｒ３의 억제제의 효과
US20090215054A1 (en) 2005-12-13 2009-08-27 Carter Scott L Prognosis indicators for solid human tumors
WO2007075672A2 (en) 2005-12-23 2007-07-05 Lankenau Institute For Medical Research Prognostic cancer markers
EP2412821B1 (en) 2006-01-11 2014-09-17 Genomic Health, Inc. AREG as a gene expression marker for colorectal cancer prognosis
ES2300176B1 (es) * 2006-02-15 2009-05-01 Consejo Superior Investig. Cientificas Metodo para el diagnostico molecular de cancer de prostata, kit para implementar el metodo.
US20070218512A1 (en) 2006-02-28 2007-09-20 Alex Strongin Methods related to mmp26 status as a diagnostic and prognostic tool in cancer management
US20090098538A1 (en) 2006-03-31 2009-04-16 Glinsky Gennadi V Prognostic and diagnostic method for disease therapy
US7914988B1 (en) 2006-03-31 2011-03-29 Illumina, Inc. Gene expression profiles to predict relapse of prostate cancer
US7888019B2 (en) 2006-03-31 2011-02-15 Genomic Health, Inc. Genes involved estrogen metabolism
WO2007140352A2 (en) 2006-05-26 2007-12-06 Invitrogen Corporation Plasma membrane and secreted cancer biomarkers
EP2029020A4 (en) 2006-06-22 2010-04-21 Wisconsin Alumni Res Found USE OF STROMA COLLAGEN IN THE DIAGNOSIS AND CHARACTERIZATION OF BREAST CANCER
WO2008036717A2 (en) 2006-09-19 2008-03-27 Emory University Use of soluble galectin-3 (gal-3) for cancer treatment
WO2008048570A2 (en) 2006-10-16 2008-04-24 The Ohio State University Research Foundation Piwil2-related biomarkers and cell lines useful therewith
WO2008046510A1 (en) 2006-10-16 2008-04-24 Bayer Healthcare Ag Fn1 as a biomarker, therapeutic and diagnostic target
WO2008067065A2 (en) * 2006-10-19 2008-06-05 Shiv Srivastava Methods, kits, and systems for diagnosing and prognosing prostate cancer using secreted biomarkers
WO2008058018A2 (en) 2006-11-02 2008-05-15 Mayo Foundation For Medical Education And Research Predicting cancer outcome
JP2010509598A (ja) 2006-11-13 2010-03-25 ライフ テクノロジーズ コーポレーション 前立腺癌バイオマーカーを検出するための方法およびキット
US20080131887A1 (en) 2006-11-30 2008-06-05 Stephan Dietrich A Genetic Analysis Systems and Methods
EP2099929A4 (en) 2006-12-06 2010-12-08 Avalon Pharmaceuticals ASSOCIATED WITH CANCER GENES AS A BIOMARKER TO MONITOR THE RESPONSE TO IMPDH INHIBITORS
AT504702A1 (de) 2006-12-22 2008-07-15 Arc Austrian Res Centers Gmbh Set von tumormarkern
JP2010517510A (ja) 2007-01-09 2010-05-27 ブリストル−マイヤーズ スクイブ カンパニー 前立腺細胞中のタンパク質チロシンキナーゼおよび／またはタンパク質チロシンキナーゼ経路と相互作用しかつ／またはそれを調節する化合物の活性を予測するためのポリヌクレオチドの同定
US20090047694A1 (en) 2007-08-17 2009-02-19 Shuber Anthony P Clinical Intervention Directed Diagnostic Methods
CA2680591A1 (en) 2007-03-15 2008-09-25 Genomic Health, Inc. Gene expression markers for prediction of patient response to chemotherapy
WO2008122447A2 (en) 2007-04-10 2008-10-16 Epigenomics Ag Dna methylation assay for the diagnosis or prognosis of medical conditions
EP2639316A1 (en) 2007-05-11 2013-09-18 The Johns Hopkins University Biomarkers for melanoma
EP2068618A4 (en) 2007-05-21 2011-01-19 Dana Farber Cancer Inst Inc COMPOSITIONS AND METHODS OF DISCOVERING TUMOR GENES
WO2009021338A1 (en) 2007-08-15 2009-02-19 UNIVERSITé DE SHERBROOKE Alternative splicing gene variants in cancer detection
AU2008314009A1 (en) 2007-09-07 2009-04-23 Universite Libre De Bruxelles Methods and tools for prognosis of cancer in HER2+ patients
WO2009051734A1 (en) 2007-10-17 2009-04-23 The General Hospital Corporation Microchip-based devices for capturing circulating tumor cells and methods of their use
GB0721605D0 (en) 2007-11-02 2007-12-12 Cancer Rec Tech Ltd Prostrate cancer susceptibility screening
US20090123439A1 (en) 2007-11-09 2009-05-14 The Jackson Laboratory Diagnostic and prognosis methods for cancer stem cells
WO2009070767A2 (en) 2007-11-28 2009-06-04 Whitehead Institute For Biomedical Research Systemic instigation systems to study tumor growth or metastasis
EP2065474A1 (en) 2007-11-28 2009-06-03 Siemens Healthcare Diagnostics GmbH A method to assess prognosis and to predict therapeutic response to endocrine treatment
EP2215251A2 (en) 2007-11-30 2010-08-11 Siemens Healthcare Diagnostics GmbH Method for predicting therapy responsiveness in basal like tumors
WO2009089521A2 (en) 2008-01-10 2009-07-16 Nuvera Biosciences, Inc. Predictors for evaluating response to cancer therapy
WO2009105154A2 (en) 2008-02-19 2009-08-27 The Jackson Laboratory Diagnostic and prognostic methods for cancer
WO2009105640A1 (en) 2008-02-22 2009-08-27 Virginia Commonwealth University Signatures associated with rejection or recurrence of cancer
WO2009114836A1 (en) 2008-03-14 2009-09-17 Genomic Health, Inc. Gene expression markers for prediction of patient response to chemotherapy
JP5550633B2 (ja) 2008-03-26 2014-07-16 セラノス， インコーポレイテッド 臨床転帰を評価するための方法およびシステム
EP2105511A1 (en) 2008-03-28 2009-09-30 Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. Medicament compositions and substances for treatment and identifying adenocarcinoma of the lung
WO2009124251A1 (en) 2008-04-03 2009-10-08 Sloan-Kettering Institute For Cancer Research Gene signatures for the prognosis of cancer
AU2008354371B2 (en) 2008-04-10 2015-07-09 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Prostate cancer-specific alterations in ERG gene expression and detection and treatment methods based on those alterations
WO2009132257A2 (en) 2008-04-25 2009-10-29 Integrated Bioscience Solutions, Llc Cytological methods for detecting cancer
US8093000B2 (en) 2008-05-09 2012-01-10 The Regents Of The University Of California Methods for predicting and treating tumors resistant to drug, immunotherapy, and radiation
JP2011521215A (ja) 2008-05-14 2011-07-21 エーテーハー チューリヒ 前立腺癌の診断及び治療のためのバイオマーカー及び薬剤標的発見法、並びにそれを用いて決定されるバイオマーカーアッセイ
CA2724231A1 (en) 2008-05-15 2009-11-19 The University Of North Carolina At Chapel Hill Novel targets for regulation of angiogenesis
WO2009140741A1 (en) 2008-05-23 2009-11-26 The University Of Queensland Agents and methods for diagnosing the presence or risk of prostate cancer
WO2009143603A1 (en) 2008-05-28 2009-12-03 Genomedx Biosciences, Inc. Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer
GB0809689D0 (en) 2008-05-28 2008-07-02 Cancer Res Inst Royal Markers for prostate cancee
US20090298082A1 (en) * 2008-05-30 2009-12-03 Klee George G Biomarker panels for predicting prostate cancer outcomes
WO2009149166A2 (en) 2008-06-03 2009-12-10 Children's Hospital Medical Center Methods and compositions for the diagnosis and treatment of proliferative disorders
RU2011101378A (ru) 2008-06-16 2012-07-27 Сайвидон Дайагностикс Гмбх (De) Алгоритмы предсказания исхода у пациентов с узловой формой рака молочной железы после химиотерапии
EP2315858A2 (en) 2008-07-08 2011-05-04 Source Precision Medicine, Inc. Gene expression profiling for predicting the survivability of prostate cancer subjects
AU2009270851A1 (en) 2008-07-16 2010-01-21 Dana-Farber Cancer Institute, Inc. Signatures and PCDETERMINANTS associated with prostate cancer and methods of use thereof
NZ590993A (en) 2008-07-21 2012-11-30 Translational Genomics Res Inst Dual specificity phosphatase 1 protein (DUSP1) for diagnosis and prognosis of skin cancer
DK2324111T3 (da) 2008-09-10 2013-09-30 Life & Brain Gmbh Yderzone-tumorceller samt fremgangsmåde til fremstilling deraf samt anvendelse deraf
JP5819728B2 (ja) 2008-10-20 2015-11-24 ファーマテスト・サービシーズ・オサケユキテュアＰｈａｒｍａｔｅｓｔ Ｓｅｒｖｉｃｅｓ Ｏｙ Ｎａｖ３の遺伝子異常および複数遺伝子の異常発現を含む方法および使用
KR20110073534A (ko) 2008-10-22 2011-06-29 제넨테크, 인크. 전립선 줄기 세포 및 그의 용도
WO2010062706A2 (en) 2008-10-30 2010-06-03 Caris Mpi, Inc. Methods for assessing rna patterns
US20110230361A1 (en) * 2008-11-14 2011-09-22 Emory University Prostate cancer biomarkers to predict recurrence and metastatic potential
US20110230372A1 (en) 2008-11-14 2011-09-22 Stc Unm Gene expression classifiers for relapse free survival and minimal residual disease improve risk classification and outcome prediction in pediatric b-precursor acute lymphoblastic leukemia
GB0821787D0 (en) 2008-12-01 2009-01-07 Univ Ulster A genomic-based method of stratifying breast cancer patients
US20110236903A1 (en) 2008-12-04 2011-09-29 Mcclelland Michael Materials and methods for determining diagnosis and prognosis of prostate cancer
AU2010203825A1 (en) 2009-01-06 2011-07-21 Genomic Health, Inc. Gene expression profiling for the identification, monitoring, and treatment of prostate cancer
CN102482711A (zh) 2009-01-07 2012-05-30 美瑞德生物工程公司 癌症生物标记
NZ624816A (en) 2009-01-14 2015-07-31 Us Health Ratio based biomarkers and methods of use thereof
ES2526519T3 (es) 2009-01-15 2015-01-13 Laboratory Corporation Of America Holdings Métodos de determinación de la respuesta del paciente por medición de la expresión HER-2
EP2233590A1 (en) 2009-01-28 2010-09-29 AIT Austrian Institute of Technology GmbH Methylation assay
EP2399130A4 (en) 2009-02-20 2012-06-06 Wayne John Cancer Inst ASSAY OF B7-H3 ANTIBODY-COUPLED BEADS FOR THE ISOLATION AND DETECTION OF CIRCULATING TUMOR CELLS IN THE BODILY FLUIDS OF MELANOMA AND BREAST CANCER PATIENTS
WO2010099577A1 (en) 2009-03-04 2010-09-10 The University Of Queensland Cancer biomarkers and uses therefor
US8554924B2 (en) 2009-03-16 2013-10-08 Apple Inc. Connection to multiple accessories with multiple accessory-specific protocols
US8765383B2 (en) 2009-04-07 2014-07-01 Genomic Health, Inc. Methods of predicting cancer risk using gene expression in premalignant tissue
EP2241634A1 (en) 2009-04-16 2010-10-20 Université Libre de Bruxelles Diagnostic method and tools to predict the effiacy of targeted agents against IGF-1 pathway activation in cancer
US20120040863A1 (en) 2009-04-16 2012-02-16 National Research Council Of Canada Process for tumour characteristic and marker set identification, tumour classification and marker sets for cancer
WO2010127399A1 (en) 2009-05-06 2010-11-11 Walter And Eliza Hall Institute Of Medical Research Gene expression profiles and uses thereof
WO2010129965A1 (en) 2009-05-08 2010-11-11 The Regents Of The University Of California Cancer specific mitotic network
US20100303795A1 (en) * 2009-05-27 2010-12-02 Soerensen Karina Dalsgaard Marker of prostate cancer
EP2452281B1 (en) 2009-07-08 2019-10-02 Worldwide Innovative Network Method for predicting efficacy of drugs in a patient
WO2011039734A2 (en) 2009-10-02 2011-04-07 Enzo Medico Use of genes involved in anchorage independence for the optimization of diagnosis and treatment of human cancer
AU2010321829B2 (en) 2009-11-23 2015-07-30 Genomic Health, Inc. Methods to predict clinical outcome of cancer
NZ705645A (en) 2010-01-11 2016-05-27 Genomic Health Inc Method to use gene expression to determine likelihood of clinical outcome of renal cancer
SG186940A1 (en) 2010-07-27 2013-02-28 Genomic Health Inc Method for using gene expression to determine prognosis of prostate cancer
WO2014108896A1 (en) 2013-01-08 2014-07-17 Marpe Technologies Ltd. Device and method for body moles mapping and tracking

Also Published As

Publication number Publication date
EP2598659B1 (en) 2015-03-11
IL251403B (en) 2018-04-30
EP2598659A4 (en) 2014-01-01
ES2611000T3 (es) 2017-05-04
EP2913405B1 (en) 2016-11-09
IL243206A (en) 2017-04-30
IL243203A (en) 2017-04-30
EP2598659A2 (en) 2013-06-05
EP4083233A2 (en) 2022-11-02
ES2741745T3 (es) 2020-02-12
JP2020031642A (ja) 2020-03-05
CA3081061C (en) 2023-01-03
US20120028264A1 (en) 2012-02-02
ES2925983T3 (es) 2022-10-20
JP2022031750A (ja) 2022-02-22
JP2013532482A (ja) 2013-08-19
EP3147373A1 (en) 2017-03-29
JP7042784B2 (ja) 2022-03-28
MX338883B (es) 2016-05-04
MX2013000996A (es) 2013-12-09
EP4083233A3 (en) 2023-01-25
CA3081061A1 (en) 2012-02-02
SG186940A1 (en) 2013-02-28
WO2012015765A3 (en) 2012-06-14
AU2011282892A1 (en) 2013-03-07
MX359416B (es) 2018-09-27
DK2598659T3 (en) 2015-05-26
US20220396842A1 (en) 2022-12-15
DK2913405T3 (en) 2017-02-13
NZ607282A (en) 2014-06-27
SG10201505769PA (en) 2015-09-29
EP3556870A1 (en) 2019-10-23
ES2537403T3 (es) 2015-06-08
US20250129432A1 (en) 2025-04-24
IL243201A (en) 2017-04-30
US20190249260A1 (en) 2019-08-15
JP6246845B2 (ja) 2017-12-13
AU2011282892B2 (en) 2015-07-16
IL251403A0 (en) 2017-05-29
EP3556870B9 (en) 2022-09-28
US10260104B2 (en) 2019-04-16
MX2018011725A (es) 2021-11-16
WO2012015765A2 (en) 2012-02-02
CA2804626C (en) 2020-07-28
HK1212395A1 (en) 2016-06-10
JP2018068299A (ja) 2018-05-10
US20200255911A1 (en) 2020-08-13
SG10201912361VA (en) 2020-02-27
MX346031B (es) 2017-03-01
EP3556870B1 (en) 2022-06-22
EP3147373B1 (en) 2019-05-15
US20160097105A1 (en) 2016-04-07
CA2804626A1 (en) 2012-02-02
JP2016178921A (ja) 2016-10-13
EP2913405A1 (en) 2015-09-02
HK1185116A1 (en) 2014-02-07
DK3147373T3 (da) 2019-08-12

Similar Documents

Publication Publication Date Title
JP7042784B2 (ja) 遺伝子発現を用いた前立腺癌の予後を定量化する方法
JP6351112B2 (ja) 前立腺癌の予後を定量化するための遺伝子発現プロフィールアルゴリズムおよび試験
US11551782B2 (en) Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer
CA2776751A1 (en) Methods to predict clinical outcome of cancer
EP2121988B1 (en) Prostate cancer survival and recurrence
US20120004127A1 (en) Gene expression markers for colorectal cancer prognosis
KR102376220B1 (ko) 전립선암에서 후기 임상적 종점을 평가하기 위한 알고리즘 및 방법
AU2017268510A1 (en) Method for using gene expression to determine prognosis of prostate cancer
US20180051342A1 (en) Prostate cancer survival and recurrence
NZ752676B2 (en) Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer
NZ711680B2 (en) Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed