MX346031B - Método para emplear expresión génica para determinar pronóstico de cáncer de próstata. - Google Patents

Método para emplear expresión génica para determinar pronóstico de cáncer de próstata.

Info

Publication number
MX346031B
MX346031B MX2016001899A MX2016001899A MX346031B MX 346031 B MX346031 B MX 346031B MX 2016001899 A MX2016001899 A MX 2016001899A MX 2016001899 A MX2016001899 A MX 2016001899A MX 346031 B MX346031 B MX 346031B
Authority
MX
Mexico
Prior art keywords
prostate cancer
patient
gene expression
likelihood
determine prognosis
Prior art date
Application number
MX2016001899A
Other languages
English (en)
Inventor
B Baker Joffre
J Pelham Robert
Crager Michael
Lee Mark
Cherbavaz Diana
Shak Steven
Maddala Tara
Goddard Audrey
L Baehner Frederick
Cowens Wayne
C Kiefer Michael
Original Assignee
Genomic Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genomic Health Inc filed Critical Genomic Health Inc
Publication of MX346031B publication Critical patent/MX346031B/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a un método para determinar una probabilidad de recurrencia del cáncer en un paciente con cáncer de próstata, que comprende: medir un nivel de expresión de KLK2 en una muestra biológica que comprende tejido de próstata obtenido del paciente; predecir una probabilidad de recurrencia del cáncer para el paciente; en donde un nivel de expresión aumentado de KLK2 está asociado negativamente con un aumento del riesgo de recurrencia.
MX2016001899A 2010-07-27 2011-07-25 Método para emplear expresión génica para determinar pronóstico de cáncer de próstata. MX346031B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US36821710P 2010-07-27 2010-07-27
US41431010P 2010-11-16 2010-11-16
US201161485536P 2011-05-12 2011-05-12
PCT/US2011/045253 WO2012015765A2 (en) 2010-07-27 2011-07-25 Method for using gene expression to determine prognosis of prostate cancer

Publications (1)

Publication Number Publication Date
MX346031B true MX346031B (es) 2017-03-01

Family

ID=45527113

Family Applications (4)

Application Number Title Priority Date Filing Date
MX2013000996A MX338883B (es) 2010-07-27 2011-07-25 Metodo para usar expresion de gen para determinar el pronostico de cancer de prostata.
MX2016001899A MX346031B (es) 2010-07-27 2011-07-25 Método para emplear expresión génica para determinar pronóstico de cáncer de próstata.
MX2016016498A MX359416B (es) 2010-07-27 2011-07-25 Metodo para emplear expresion genica para determinar pronostico de cancer de prostata.
MX2018011725A MX2018011725A (es) 2010-07-27 2013-01-24 Metodo para emplear expresion genica para determinar pronostico de cancer de prostata.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2013000996A MX338883B (es) 2010-07-27 2011-07-25 Metodo para usar expresion de gen para determinar el pronostico de cancer de prostata.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2016016498A MX359416B (es) 2010-07-27 2011-07-25 Metodo para emplear expresion genica para determinar pronostico de cancer de prostata.
MX2018011725A MX2018011725A (es) 2010-07-27 2013-01-24 Metodo para emplear expresion genica para determinar pronostico de cancer de prostata.

Country Status (12)

Country Link
US (6) US20120028264A1 (es)
EP (5) EP2913405B1 (es)
JP (5) JP2013532482A (es)
AU (1) AU2011282892B2 (es)
CA (2) CA2804626C (es)
DK (3) DK3147373T3 (es)
ES (4) ES2741745T3 (es)
IL (5) IL243206A (es)
MX (4) MX338883B (es)
NZ (1) NZ607282A (es)
SG (3) SG10201505769PA (es)
WO (1) WO2012015765A2 (es)

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