IL196064A - Epoxytone peptide for proteasome inhibition - Google Patents
Epoxytone peptide for proteasome inhibitionInfo
- Publication number
- IL196064A IL196064A IL196064A IL19606408A IL196064A IL 196064 A IL196064 A IL 196064A IL 196064 A IL196064 A IL 196064A IL 19606408 A IL19606408 A IL 19606408A IL 196064 A IL196064 A IL 196064A
- Authority
- IL
- Israel
- Prior art keywords
- proteasome inhibition
- peptide epoxyketones
- epoxyketones
- peptide
- proteasome
- Prior art date
Links
- 102000004245 Proteasome Endopeptidase Complex Human genes 0.000 title 1
- 108090000708 Proteasome Endopeptidase Complex Proteins 0.000 title 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N epoxyketone group Chemical group O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
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- C07K5/1002—Tetrapeptides with the first amino acid being neutral
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| MY171061A (en) * | 2005-11-09 | 2019-09-24 | Onyx Therapeutics Inc | Compounds for enzyme inhibition |
| CA2657213C (en) | 2006-06-19 | 2017-01-03 | Proteolix, Inc. | Peptide epoxyketones for proteasome inhibition |
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