AU4499697A - Method for treating parasitic diseases with proteasome inhibitors - Google Patents

Method for treating parasitic diseases with proteasome inhibitors

Info

Publication number
AU4499697A
AU4499697A AU44996/97A AU4499697A AU4499697A AU 4499697 A AU4499697 A AU 4499697A AU 44996/97 A AU44996/97 A AU 44996/97A AU 4499697 A AU4499697 A AU 4499697A AU 4499697 A AU4499697 A AU 4499697A
Authority
AU
Australia
Prior art keywords
proteasome inhibitors
parasitic diseases
treating parasitic
treating
diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU44996/97A
Inventor
Daniel Eichinger
Jorge Gonzales
Victor Nussenzweig
Photini Sinnis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York University NYU
Original Assignee
New York University NYU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York University NYU filed Critical New York University NYU
Publication of AU4499697A publication Critical patent/AU4499697A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU44996/97A 1996-09-13 1997-09-12 Method for treating parasitic diseases with proteasome inhibitors Abandoned AU4499697A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2589496P 1996-09-13 1996-09-13
US60025894 1996-09-13
PCT/US1997/017136 WO1998010779A1 (en) 1996-09-13 1997-09-12 Method for treating parasitic diseases with proteasome inhibitors

Publications (1)

Publication Number Publication Date
AU4499697A true AU4499697A (en) 1998-04-02

Family

ID=21828635

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44996/97A Abandoned AU4499697A (en) 1996-09-13 1997-09-12 Method for treating parasitic diseases with proteasome inhibitors

Country Status (2)

Country Link
AU (1) AU4499697A (en)
WO (1) WO1998010779A1 (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103554222A (en) 2004-04-15 2014-02-05 欧尼斯治疗公司 Compounds for enzyme inhibition
US8198270B2 (en) 2004-04-15 2012-06-12 Onyx Therapeutics, Inc. Compounds for proteasome enzyme inhibition
US7232818B2 (en) 2004-04-15 2007-06-19 Proteolix, Inc. Compounds for enzyme inhibition
SI2030981T1 (en) 2004-05-10 2014-11-28 Onyx Therapeutics, Inc. Compounds for proteasome enzyme inhibition
US20060088471A1 (en) 2004-10-20 2006-04-27 Proteolix, Inc. Compounds for enzyme inhibition
PT2261236E (en) 2004-12-07 2015-10-30 Onyx Therapeutics Inc Composition for proteasome inhibition
DE602006017359D1 (en) 2005-05-27 2010-11-18 Proteolix Inc SUBSTRATE FOR RPN-11 ENZYME ACTIVITY
AU2006311584B2 (en) 2005-11-09 2012-03-08 Onyx Therapeutics, Inc. Compounds for enzyme inhibition
AU2007261345B2 (en) 2006-06-19 2012-02-23 Onyx Therapeutics, Inc. Peptide epoxyketones for proteasome inhibition
KR20170125413A (en) 2007-10-04 2017-11-14 오닉스 세라퓨틱스, 인크. Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides
CA2741312C (en) 2008-10-21 2020-10-27 Onyx Therapeutics, Inc. Combination therapy with peptide epoxyketones
TWI504598B (en) 2009-03-20 2015-10-21 Onyx Therapeutics Inc Crystalline tripeptide epoxy ketone protease inhibitors
JP5919196B2 (en) 2009-11-13 2016-05-18 オニキス セラピューティクス， インク．Ｏｎｙｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． Use of peptide epoxy ketones for metastasis inhibition
SG183843A1 (en) 2010-03-01 2012-10-30 Onyx Therapeutics Inc Compounds for immunoproteasome inhibition
KR20190137963A (en) 2012-05-08 2019-12-11 오닉스 세라퓨틱스, 인크. Cyclodextrin complexation methods for formulating peptide proteasome inhibitors
JP2015524394A (en) 2012-07-09 2015-08-24 オニキス セラピューティクス， インク．Ｏｎｙｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． Prodrugs of peptide epoxyketone protease inhibitors
AU2013292636A1 (en) 2012-07-18 2015-02-05 Onyx Therapeutics, Inc. Liposomal compositions of epoxyketone-based proteasome inhibitors
CN107459508A (en) 2012-07-20 2017-12-12 克里弗生物科学公司 Annelated pyrimidines as the inhibitor of P97 compounds
WO2014066506A2 (en) 2012-10-23 2014-05-01 Cleave Biosciences, Inc. Compositions and methods for jamm protein inhibition
TW201422255A (en) 2012-10-24 2014-06-16 Onyx Therapeutics Inc Modified release formulations for oprozomib
SG11201507106PA (en) 2013-03-14 2015-10-29 Onyx Therapeutics Inc Dipeptide and tripeptide epoxy ketone protease inhibitors
AR095426A1 (en) 2013-03-14 2015-10-14 Onyx Therapeutics Inc TRIPEPTIDE INHIBITORS OF PROTEASA EPOXYCETONE
WO2014151630A2 (en) 2013-03-15 2014-09-25 Irm Llc Compounds and compositions for the treatment of parasitic diseases
US9186361B2 (en) 2013-03-15 2015-11-17 Novartis Ag Compounds and compositions for the treatment of parasitic diseases
US9296754B2 (en) 2013-03-15 2016-03-29 Novartis Ag Compounds and compositions for the treatment of parasitic diseases
WO2015089218A1 (en) 2013-12-10 2015-06-18 David Wustrow Monocyclic pyrimidine/pyridine compounds as inhibitors of p97 complex
HUE040254T2 (en) * 2013-12-19 2019-02-28 Novartis Ag [1,2,4]triazolo[1,5-a]pyrimidine derivatives as protozoan proteasome inhibitors for the treatment of parasitic diseases such as leishmaniasis
CN106458996B (en) 2014-01-20 2020-11-03 克里弗生物科学公司 Fused pyrimidines as inhibitors of the p97 complex
KR102524751B1 (en) 2016-06-29 2023-04-21 케자르 라이프 사이언스 Preparation method of peptide epoxyketone immunoprotease inhibitor and its precursor
LT3478670T (en) 2016-06-29 2023-05-25 Kezar Life Sciences Crystalline salts of peptide epoxyketone immunoproteasome inhibitor
JP2019529458A (en) 2016-09-21 2019-10-17 小野薬品工業株式会社 Immediate release formulation for Oprozomib
US20180161279A1 (en) 2016-12-14 2018-06-14 Amgen Inc. Gastro-retentive modified release dosage forms for oprozomib and process to make thereof
EP4087538A1 (en) 2020-01-10 2022-11-16 Amgen, Inc. Stable cyclodextrin free carfilzomib formulation
WO2021142359A1 (en) 2020-01-10 2021-07-15 Amgen Inc. Stable cyclodextrin free carfilzomib formulation

Also Published As

Publication number Publication date
WO1998010779A1 (en) 1998-03-19

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