IL153515A0 - 1,3-dioxolanes with antitussive activity - Google Patents
1,3-dioxolanes with antitussive activityInfo
- Publication number
- IL153515A0 IL153515A0 IL15351501A IL15351501A IL153515A0 IL 153515 A0 IL153515 A0 IL 153515A0 IL 15351501 A IL15351501 A IL 15351501A IL 15351501 A IL15351501 A IL 15351501A IL 153515 A0 IL153515 A0 IL 153515A0
- Authority
- IL
- Israel
- Prior art keywords
- dioxolanes
- antitussive activity
- preparation
- acetals
- antitussive
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Glass Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2000MI001734A IT1318650B1 (it) | 2000-07-28 | 2000-07-28 | 1,3-diossolani ad attivita' antitosse. |
PCT/EP2001/008304 WO2002010149A1 (en) | 2000-07-28 | 2001-07-18 | 1,3-dioxolanes with antitussive activity |
Publications (1)
Publication Number | Publication Date |
---|---|
IL153515A0 true IL153515A0 (en) | 2003-07-06 |
Family
ID=11445591
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15351501A IL153515A0 (en) | 2000-07-28 | 2001-07-18 | 1,3-dioxolanes with antitussive activity |
IL153515A IL153515A (en) | 2000-07-28 | 2002-12-18 | 1,3 - Dioxalenes with cough suppressant activity |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL153515A IL153515A (en) | 2000-07-28 | 2002-12-18 | 1,3 - Dioxalenes with cough suppressant activity |
Country Status (27)
Country | Link |
---|---|
US (1) | US6835734B2 (hu) |
EP (1) | EP1307441B1 (hu) |
JP (1) | JP5107497B2 (hu) |
KR (1) | KR100781403B1 (hu) |
CN (1) | CN1204135C (hu) |
AT (1) | ATE266018T1 (hu) |
AU (1) | AU2001287638A1 (hu) |
BR (1) | BR0112765A (hu) |
CZ (1) | CZ301087B6 (hu) |
DE (1) | DE60103164T2 (hu) |
DK (1) | DK1307441T3 (hu) |
EE (1) | EE05178B1 (hu) |
ES (1) | ES2219562T3 (hu) |
HK (1) | HK1058797A1 (hu) |
HU (1) | HUP0301497A3 (hu) |
IL (2) | IL153515A0 (hu) |
IT (1) | IT1318650B1 (hu) |
MX (1) | MXPA02012920A (hu) |
PL (1) | PL206307B1 (hu) |
PT (1) | PT1307441E (hu) |
RS (1) | RS50861B (hu) |
RU (1) | RU2276149C2 (hu) |
SI (1) | SI21040A (hu) |
SK (1) | SK286794B6 (hu) |
TR (1) | TR200401315T4 (hu) |
UA (1) | UA73789C2 (hu) |
WO (1) | WO2002010149A1 (hu) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1318651B1 (it) * | 2000-07-28 | 2003-08-27 | Dompe Spa | Sintesi di (+-)1,3-diossolani e loro risoluzione ottica. |
TWI496776B (zh) * | 2007-11-15 | 2015-08-21 | Astrazeneca Ab | 製備(3aR,4S,6R,6aS)-6-胺基-2,2-二甲基四氫-3aH-環戊并[d][1,3]二氧雜環戊烯-4-醇之純非對映異構性之二苯甲醯-L-酒石酸鹽之方法 |
EP2070915A1 (en) * | 2007-12-03 | 2009-06-17 | A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. | New process for the synthesis of moguisteine |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4049660A (en) * | 1971-06-18 | 1977-09-20 | Delalande S.A. | N-substituted derivatives of 4 (N-piperazinylmethyl) spiro dibenzocycloheptadi- (or tri-) ene-5, 2-dioxolane (1,3) their method of preparation and their application in therapeutics |
IT1203721B (it) * | 1983-12-29 | 1989-02-23 | Dompe Farmaceutici Spa | Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono |
NL8801622A (nl) * | 1988-06-25 | 1990-01-16 | Stamicarbon | Bereiding van enantiomeren van dropropizine. |
IT1226570B (it) * | 1988-08-01 | 1991-01-24 | Bidachem Spa | Procedimento di preparazione della levo- e destro-dropropizina |
IT1254452B (it) * | 1992-02-14 | 1995-09-25 | Dompe Farmaceutici Spa | N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli |
IT1254993B (it) * | 1992-06-24 | 1995-10-11 | Procedimento per la preparazione degli enantiomeri della dropropizina | |
IL111730A (en) * | 1993-11-29 | 1998-12-06 | Fujisawa Pharmaceutical Co | Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them |
IT1318651B1 (it) * | 2000-07-28 | 2003-08-27 | Dompe Spa | Sintesi di (+-)1,3-diossolani e loro risoluzione ottica. |
-
2000
- 2000-07-28 IT IT2000MI001734A patent/IT1318650B1/it active
-
2001
- 2001-07-18 CN CNB018134564A patent/CN1204135C/zh not_active Expired - Fee Related
- 2001-07-18 DE DE60103164T patent/DE60103164T2/de not_active Expired - Lifetime
- 2001-07-18 CZ CZ20030268A patent/CZ301087B6/cs not_active IP Right Cessation
- 2001-07-18 PT PT01967203T patent/PT1307441E/pt unknown
- 2001-07-18 PL PL361172A patent/PL206307B1/pl not_active IP Right Cessation
- 2001-07-18 RS YUP-30/03A patent/RS50861B/sr unknown
- 2001-07-18 BR BR0112765-9A patent/BR0112765A/pt not_active Application Discontinuation
- 2001-07-18 EE EEP200300036A patent/EE05178B1/xx not_active IP Right Cessation
- 2001-07-18 HU HU0301497A patent/HUP0301497A3/hu unknown
- 2001-07-18 AT AT01967203T patent/ATE266018T1/de active
- 2001-07-18 SK SK89-2003A patent/SK286794B6/sk not_active IP Right Cessation
- 2001-07-18 JP JP2002515880A patent/JP5107497B2/ja not_active Expired - Fee Related
- 2001-07-18 IL IL15351501A patent/IL153515A0/xx active IP Right Grant
- 2001-07-18 KR KR1020037000945A patent/KR100781403B1/ko not_active IP Right Cessation
- 2001-07-18 EP EP01967203A patent/EP1307441B1/en not_active Expired - Lifetime
- 2001-07-18 TR TR2004/01315T patent/TR200401315T4/xx unknown
- 2001-07-18 ES ES01967203T patent/ES2219562T3/es not_active Expired - Lifetime
- 2001-07-18 WO PCT/EP2001/008304 patent/WO2002010149A1/en active IP Right Grant
- 2001-07-18 UA UA2003021767A patent/UA73789C2/uk unknown
- 2001-07-18 AU AU2001287638A patent/AU2001287638A1/en not_active Abandoned
- 2001-07-18 MX MXPA02012920A patent/MXPA02012920A/es active IP Right Grant
- 2001-07-18 RU RU2003105691/04A patent/RU2276149C2/ru not_active IP Right Cessation
- 2001-07-18 DK DK01967203T patent/DK1307441T3/da active
- 2001-07-18 SI SI200120036A patent/SI21040A/sl not_active IP Right Cessation
- 2001-07-18 US US10/333,979 patent/US6835734B2/en not_active Expired - Fee Related
-
2002
- 2002-12-18 IL IL153515A patent/IL153515A/en not_active IP Right Cessation
-
2004
- 2004-03-05 HK HK04101653A patent/HK1058797A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
FF | Patent granted | ||
KB | Patent renewed |