PL351145A1 - Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof - Google Patents

Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof

Info

Publication number
PL351145A1
PL351145A1 PL00351145A PL35114500A PL351145A1 PL 351145 A1 PL351145 A1 PL 351145A1 PL 00351145 A PL00351145 A PL 00351145A PL 35114500 A PL35114500 A PL 35114500A PL 351145 A1 PL351145 A1 PL 351145A1
Authority
PL
Poland
Prior art keywords
dimethyl
salts
preparation
intermediates
dioxane
Prior art date
Application number
PL00351145A
Inventor
Nagy Peter Kotay
Zoltan Greff
Jozsef Barkoczy
Gyula Simig
Laszlo Balazs
Imre Doman
Zoltan Ratkai
Peter Seres
Ferenc Bartha
Donath Gyorgyi Vereczkeyne
Kalman Nagy
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of PL351145A1 publication Critical patent/PL351145A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
PL00351145A 1999-05-06 2000-05-05 Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof PL351145A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9901526A HU227840B1 (en) 1999-05-06 1999-05-06 Intermediates of atorvastatin synthesis and process for producing them
PCT/HU2000/000042 WO2000068221A1 (en) 1999-05-06 2000-05-05 Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof

Publications (1)

Publication Number Publication Date
PL351145A1 true PL351145A1 (en) 2003-03-24

Family

ID=89998261

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00351145A PL351145A1 (en) 1999-05-06 2000-05-05 Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof

Country Status (14)

Country Link
EP (1) EP1178980A1 (en)
JP (1) JP2002544207A (en)
KR (1) KR20020033617A (en)
CN (1) CN1349522A (en)
AU (1) AU4600200A (en)
CA (1) CA2373077A1 (en)
CZ (1) CZ20013965A3 (en)
HK (1) HK1046271A1 (en)
HR (1) HRP20010846A2 (en)
HU (1) HU227840B1 (en)
PL (1) PL351145A1 (en)
RU (1) RU2001133066A (en)
SK (1) SK15842001A3 (en)
WO (1) WO2000068221A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (en) 2000-07-19 2002-01-22 Dsm Nv Process for the preparation of 2- (6-substituted-1,3-dioxan-4-yl) acetic acid derivatives.
WO2002057229A1 (en) 2001-01-19 2002-07-25 Biocon India Limited FORM V CRYSTALLINE [R-(R*,R*)]-2-(4-FLUOROPHENYL)-ß,$G(D)-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1- HEPTANOIC ACID HEMI CALCIUM SALT. (ATORVASTATIN)
EP1406860A1 (en) 2001-07-06 2004-04-14 Teva Pharmaceutical Industries Limited Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives via 6-cyano syn 3,5-dihydroxy hexanoic acid derivatives
EP1323717A1 (en) 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
EP1375493A1 (en) * 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
EP1861364B1 (en) 2005-03-14 2011-05-11 C.P. Pharmaceuticals International C.V. Preparation of an atorvastatin intermediate using a paal-knorr condensation
WO2007034909A1 (en) * 2005-09-22 2007-03-29 Kaneka Corporation Process for production of (3r,5r)-7-amino-3,5-dihydroxyheptanoic acid derivative
WO2012032035A1 (en) 2010-09-09 2012-03-15 Dsm Sinochem Pharmaceuticals Netherlands B.V. Salts of 7-amino-3,5-dihydroxyheptanoic acid esters
EP3333155B1 (en) 2015-08-05 2023-05-24 API Corporation Method for producing pitavastatin calcium
CN108191813B (en) * 2017-12-20 2020-01-17 帕潘纳(北京)科技有限公司 Preparation method of ketal
CN109232353A (en) * 2018-10-09 2019-01-18 河南师范大学 A kind of preparation method of Atorvastatin calcium condensation product
CN109232354A (en) * 2018-10-09 2019-01-18 河南师范大学 A kind of preparation method of high purity atorvastatin calcium raw material drug
CN110940764B (en) * 2019-12-31 2022-06-28 湖南九典制药股份有限公司 Separation method of statin optical isomer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5003080A (en) * 1988-02-22 1991-03-26 Warner-Lambert Company Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis
US5103024A (en) * 1990-10-17 1992-04-07 Warner-Lambert Company Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
US5155251A (en) * 1991-10-11 1992-10-13 Warner-Lambert Company Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate
US5278313A (en) * 1992-03-27 1994-01-11 E. R. Squibb & Sons, Inc. Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors
JP3652394B2 (en) * 1995-01-27 2005-05-25 高砂香料工業株式会社 N-substituted-7-amino-5-hydroxy-3-oxoheptanoic acid derivative and process for producing the same
US5998633A (en) * 1996-07-29 1999-12-07 Warner-Lambert Company Process for the synthesis of protected esters of (S)-3,4-dihydroxybutyric acid
DE69910562T2 (en) * 1998-04-30 2004-06-17 Kaneka Corp. METHOD FOR PRODUCING DERIVATIVES OF 6-CYANOMETHYL-1,3-DIOXANE-4-ACETIC ACID

Also Published As

Publication number Publication date
AU4600200A (en) 2000-11-21
HK1046271A1 (en) 2003-01-03
HU9901526D0 (en) 1999-07-28
CZ20013965A3 (en) 2002-04-17
CN1349522A (en) 2002-05-15
CA2373077A1 (en) 2000-11-16
HUP9901526A2 (en) 2001-04-28
WO2000068221A1 (en) 2000-11-16
SK15842001A3 (en) 2002-04-04
HRP20010846A2 (en) 2003-02-28
JP2002544207A (en) 2002-12-24
KR20020033617A (en) 2002-05-07
HU227840B1 (en) 2012-05-02
RU2001133066A (en) 2004-02-27
EP1178980A1 (en) 2002-02-13

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Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)