HK1046271A1 - Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof - Google Patents

Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof

Info

Publication number
HK1046271A1
HK1046271A1 HK02105736.6A HK02105736A HK1046271A1 HK 1046271 A1 HK1046271 A1 HK 1046271A1 HK 02105736 A HK02105736 A HK 02105736A HK 1046271 A1 HK1046271 A1 HK 1046271A1
Authority
HK
Hong Kong
Prior art keywords
dimethyl
salts
preparation
intermediates
dioxane
Prior art date
Application number
HK02105736.6A
Other languages
Chinese (zh)
Inventor
Kotay Nagy Peter
Greff Zoltan
Barkoczy Jozsef
Simig Gyula
Balazs Laszlo
Doman Imre
Ratkai Zoltan
Seres Peter
Bartha Ferenc
Vereczkeyne Donath Gyorgyi
Nagy Kalman
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of HK1046271A1 publication Critical patent/HK1046271A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK02105736.6A 1999-05-06 2002-08-06 Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof HK1046271A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9901526A HU227840B1 (en) 1999-05-06 1999-05-06 Intermediates of atorvastatin synthesis and process for producing them
PCT/HU2000/000042 WO2000068221A1 (en) 1999-05-06 2000-05-05 Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof

Publications (1)

Publication Number Publication Date
HK1046271A1 true HK1046271A1 (en) 2003-01-03

Family

ID=89998261

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02105736.6A HK1046271A1 (en) 1999-05-06 2002-08-06 Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof

Country Status (14)

Country Link
EP (1) EP1178980A1 (en)
JP (1) JP2002544207A (en)
KR (1) KR20020033617A (en)
CN (1) CN1349522A (en)
AU (1) AU4600200A (en)
CA (1) CA2373077A1 (en)
CZ (1) CZ20013965A3 (en)
HK (1) HK1046271A1 (en)
HR (1) HRP20010846A2 (en)
HU (1) HU227840B1 (en)
PL (1) PL351145A1 (en)
RU (1) RU2001133066A (en)
SK (1) SK15842001A3 (en)
WO (1) WO2000068221A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (en) 2000-07-19 2002-01-22 Dsm Nv Process for the preparation of 2- (6-substituted-1,3-dioxan-4-yl) acetic acid derivatives.
WO2002057229A1 (en) * 2001-01-19 2002-07-25 Biocon India Limited FORM V CRYSTALLINE [R-(R*,R*)]-2-(4-FLUOROPHENYL)-ß,$G(D)-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1- HEPTANOIC ACID HEMI CALCIUM SALT. (ATORVASTATIN)
IL159719A0 (en) 2001-07-06 2004-06-20 Teva Pharma Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives via 6-cyano syn 3,5-dihydroxy hexanoic acid derivatives
EP1323717A1 (en) 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
EP1375493A1 (en) * 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
IE20060197A1 (en) 2005-03-14 2006-10-18 Pfizer Science & Tech Ltd Preparation of an atorvastatin intermediate
WO2007034909A1 (en) * 2005-09-22 2007-03-29 Kaneka Corporation Process for production of (3r,5r)-7-amino-3,5-dihydroxyheptanoic acid derivative
EP2614057B1 (en) * 2010-09-09 2015-10-21 DSM Sinochem Pharmaceuticals Netherlands B.V. Salts of 7-amino-3,5-dihydroxyheptanoic acid esters
EP3333155B1 (en) 2015-08-05 2023-05-24 API Corporation Method for producing pitavastatin calcium
CN108191813B (en) * 2017-12-20 2020-01-17 帕潘纳(北京)科技有限公司 Preparation method of ketal
CN109232354A (en) * 2018-10-09 2019-01-18 河南师范大学 A kind of preparation method of high purity atorvastatin calcium raw material drug
CN109232353A (en) * 2018-10-09 2019-01-18 河南师范大学 A kind of preparation method of Atorvastatin calcium condensation product
CN110940764B (en) * 2019-12-31 2022-06-28 湖南九典制药股份有限公司 Separation method of statin optical isomer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5003080A (en) * 1988-02-22 1991-03-26 Warner-Lambert Company Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis
US5103024A (en) * 1990-10-17 1992-04-07 Warner-Lambert Company Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
US5155251A (en) * 1991-10-11 1992-10-13 Warner-Lambert Company Process for the synthesis of (5R)-1,1-dimethylethyl-6-cyano-5-hydroxy-3-oxo-hexanoate
US5278313A (en) * 1992-03-27 1994-01-11 E. R. Squibb & Sons, Inc. Process for the preparation of 1,3-dioxane derivatives useful in the preparation of HMG-COA reductase inhibitors
JP3652394B2 (en) * 1995-01-27 2005-05-25 高砂香料工業株式会社 N-substituted-7-amino-5-hydroxy-3-oxoheptanoic acid derivative and process for producing the same
TR199900191T2 (en) * 1996-07-29 1999-04-21 Warner-Lambert Company Improved process for the synthesis of protected esters of (S)-3,4-Dihydroxybutyric acid.
CA2329893A1 (en) * 1998-04-30 1999-11-11 Kaneka Corporation Process for producing 6-cyanomethyl-1,3-dioxane-4-acetic acid derivatives

Also Published As

Publication number Publication date
HU9901526D0 (en) 1999-07-28
HRP20010846A2 (en) 2003-02-28
CA2373077A1 (en) 2000-11-16
PL351145A1 (en) 2003-03-24
SK15842001A3 (en) 2002-04-04
WO2000068221A1 (en) 2000-11-16
HU227840B1 (en) 2012-05-02
JP2002544207A (en) 2002-12-24
HUP9901526A2 (en) 2001-04-28
AU4600200A (en) 2000-11-21
CZ20013965A3 (en) 2002-04-17
CN1349522A (en) 2002-05-15
RU2001133066A (en) 2004-02-27
EP1178980A1 (en) 2002-02-13
KR20020033617A (en) 2002-05-07

Similar Documents

Publication Publication Date Title
HK1089447A1 (en) A process for the preparation of 2-aminocarbonyl-9h-purine derivatives and the intermediates thereof
HK1028769A1 (en) 2-aryl-8-oxodihydropurine derivatives, process for producing the same, medicinal compositions containing the same, and intermediates thereof
HUP0004388A3 (en) Process for the preparation of oxazolidinones, intermediates and preparation thereof
EG21990A (en) Method for the manufacture of brushware
GB2362647B (en) "Method for the preparation of citalopram"
IT1315269B1 (en) METHOD FOR THE PREPARATION OF 5-CYANPHTHALIDE
HUP0101375A3 (en) Novel cephalotaxane derivatives, process for their preparation and intermediates
PL351145A1 (en) Salts of 2,2-dimethyl-1,3-dioxane intermediates and process for the preparation thereof
SG118060A1 (en) Process for preparation of pyrazoloÄ4,3-dÜpyrimidin-7-ones and intermediates thereof
HK1043131A1 (en) Process for the preparation of benzoxazine derivatives and intermediates therefor
HUP0000524A3 (en) Process for the preparation of thiazole derivatives, intermediates and preparation thereof
HUP0104193A3 (en) An improved process for the preparation of new antidiabetic agents
AU1651001A (en) Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof
EG22846A (en) Process for the preparation of urea
HUP0202819A3 (en) Process for the preparation of thiazole derivatives and the new intermediates
PL343629A1 (en) Improved process for the manufacture of n-(1-cyanoalkyl)-2-phenoxypropionamide derivatives
HUP0201400A3 (en) Method for producing 2,2,4,4-tetra-substituted 1,3,5-cyclohexanetriones and their new intermediates
HUP9900761A3 (en) A process for the preparation of 4-(desdimethyl-amino)-tetracyclines
HK1045989A1 (en) Method for the preparation of urea
HUP0301515A3 (en) Process for the preparation of chiral 1,4-diaryl-2-fluoro-2-butenes and their intermediates
EG22758A (en) Process for the preparation of urea
EE200000369A (en) Process for the preparation of isopropylmethyl [2- (3-n-propoxyphenoxy) ethyl] amine
HK1041606B (en) Process for the preparation of n,n'-carbonylbislactams
PL347407A1 (en) Method of obtaining derivatives of 5,6,7,8-tetrahydronaphtalen-2-ole
AU5514199A (en) Process for the preparation of 2-(aryloxymethyl)-2,5,7,8-tetramethylchroman-6-ols