IL150613A0 - Dibenzo (b,f) azepine intermediates - Google Patents

Dibenzo (b,f) azepine intermediates

Info

Publication number
IL150613A0
IL150613A0 IL15061301A IL15061301A IL150613A0 IL 150613 A0 IL150613 A0 IL 150613A0 IL 15061301 A IL15061301 A IL 15061301A IL 15061301 A IL15061301 A IL 15061301A IL 150613 A0 IL150613 A0 IL 150613A0
Authority
IL
Israel
Prior art keywords
dibenzo
azepine
intermediates
azepine intermediates
Prior art date
Application number
IL15061301A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9885081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL150613(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL150613A0 publication Critical patent/IL150613A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL15061301A 2000-02-07 2001-02-07 Dibenzo (b,f) azepine intermediates IL150613A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0002740.9A GB0002740D0 (en) 2000-02-07 2000-02-07 Organic compounds
PCT/EP2001/001330 WO2001056992A2 (en) 2000-02-07 2001-02-07 Dibenzo (b,f) azepine intermediates

Publications (1)

Publication Number Publication Date
IL150613A0 true IL150613A0 (en) 2003-02-12

Family

ID=9885081

Family Applications (3)

Application Number Title Priority Date Filing Date
IL15061301A IL150613A0 (en) 2000-02-07 2001-02-07 Dibenzo (b,f) azepine intermediates
IL150613A IL150613A (en) 2000-02-07 2002-07-04 Processes for the preparation of Dibenzo (F, B) intermediates
IL188183A IL188183A (en) 2000-02-07 2007-12-17 Intermediates of Dibenzo (F, B) Azpine

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL150613A IL150613A (en) 2000-02-07 2002-07-04 Processes for the preparation of Dibenzo (F, B) intermediates
IL188183A IL188183A (en) 2000-02-07 2007-12-17 Intermediates of Dibenzo (F, B) Azpine

Country Status (33)

Country Link
US (1) US7112673B2 (de)
EP (2) EP1265868B1 (de)
JP (1) JP4859322B2 (de)
KR (5) KR20080103608A (de)
CN (2) CN1244563C (de)
AR (2) AR029442A1 (de)
AT (2) ATE505459T1 (de)
AU (1) AU767724B2 (de)
BR (1) BR0107922A (de)
CA (3) CA2395601C (de)
CO (1) CO5271705A1 (de)
CY (1) CY1111567T1 (de)
CZ (1) CZ301572B6 (de)
DE (2) DE60138271D1 (de)
DK (1) DK2067772T3 (de)
ES (2) ES2324900T3 (de)
GB (1) GB0002740D0 (de)
HU (1) HU229420B1 (de)
IL (3) IL150613A0 (de)
MX (1) MXPA02007629A (de)
MY (1) MY136474A (de)
NO (1) NO324949B1 (de)
NZ (1) NZ520329A (de)
PE (1) PE20011078A1 (de)
PL (2) PL214039B1 (de)
PT (2) PT1265868E (de)
RU (1) RU2303591C2 (de)
SI (1) SI2067772T1 (de)
SK (1) SK287217B6 (de)
TR (1) TR200201655T2 (de)
TW (1) TWI284638B (de)
WO (1) WO2001056992A2 (de)
ZA (1) ZA200206219B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1302464A1 (de) * 2001-10-09 2003-04-16 Max India Limited Verfahren zur Herstellung von 10-Methoxycarbamazepin
US6670472B2 (en) 2001-10-09 2003-12-30 Max India Limited Process for the preparation of 10-methoxycarbamazepine
US7091339B2 (en) 2002-06-14 2006-08-15 Taro Pharmaceuticals Usa, Inc. Method of preparing a 5H-dibenz(b,f)azepine-5-carboxamide
ITMI20040452A1 (it) 2004-03-09 2004-06-09 Clariant Lsm Italia Spa Processo per la preparazione di oxcarbazepina
MX2007014114A (es) 2005-05-10 2008-03-14 Intermune Inc Derivados de piridona para modular el sistema de proteina cinasa activada por estres.
EP2359830B1 (de) * 2006-04-26 2012-09-19 Supernus Pharmaceuticals, Inc. Oxcarbazepinpräparate für kontrollierte Freisetzung mit sigmoidalem Freisetzungsprofil
US20090082335A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched oxcarbazepine
JP5627574B2 (ja) 2008-06-03 2014-11-19 インターミューン， インコーポレイテッド 炎症性および線維性疾患を治療するための化合物および方法
EP2900640A1 (de) 2012-09-26 2015-08-05 Ranbaxy Laboratories Limited Verfahren zur herstellung von oxcarbazepin und dessen verwendung als zwischenprodukt bei der herstellung von eslicarbazepinacetat
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
EP3043790B1 (de) * 2013-09-11 2021-05-26 The Administrators of the Tulane Educational Fund Neuartige anthranilamide und verwendung davon
US10233195B2 (en) 2014-04-02 2019-03-19 Intermune, Inc. Anti-fibrotic pyridinones

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847374A (en) * 1987-01-27 1989-07-11 Ciba-Geigy Corporation Process for the manufacture of N,N-(Dibenzohexatrienylene)ureas
DE4305502A1 (de) * 1993-02-23 1994-08-25 Basf Ag Ortho-substituierte 2-Methoxyiminophenylessigsäuremethylamide
IT1272897B (it) * 1995-01-13 1997-07-01 I F C Iniziative Finanziaarie Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
US6355680B1 (en) * 1996-02-20 2002-03-12 Exocell, Inc. Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
IT1283594B1 (it) * 1996-04-12 1998-04-22 Trifarma Srl Derivati della 5h-dibenz- (b,f)-azepin-5-carbossiammide, loro preparazione e uso come sostanze ad azione medicinale
JP2002509536A (ja) * 1997-07-01 2002-03-26 ワーナー−ランバート・カンパニー ２−（４−ブロモ又は４−ヨードフェニルアミノ）安息香酸誘導体及びｍｅｋ阻害物質としてのそれらの使用
US6048856A (en) 1997-12-17 2000-04-11 Novo Nordisk A/S Heterocyclic compounds

Also Published As

Publication number Publication date
GB0002740D0 (en) 2000-03-29
HK1052501A1 (en) 2003-09-19
CN100455572C (zh) 2009-01-28
CO5271705A1 (es) 2003-04-30
RU2002123334A (ru) 2004-01-10
MXPA02007629A (es) 2002-12-13
KR100966209B1 (ko) 2010-06-25
EP2067772B1 (de) 2011-04-13
IL188183A (en) 2011-02-28
PT1265868E (pt) 2009-07-15
ZA200206219B (en) 2003-04-04
PL356404A1 (en) 2004-06-28
SK11262002A3 (sk) 2003-02-04
EP1265868B1 (de) 2009-04-08
NO324949B1 (no) 2008-01-14
ATE505459T1 (de) 2011-04-15
CY1111567T1 (el) 2015-10-07
HU229420B1 (en) 2013-12-30
CA2395601C (en) 2010-01-05
NZ520329A (en) 2003-11-28
MY136474A (en) 2008-10-31
CA2639210C (en) 2011-05-03
JP2003521536A (ja) 2003-07-15
US7112673B2 (en) 2006-09-26
CN1244563C (zh) 2006-03-08
NO20023575L (no) 2002-07-26
DK2067772T3 (da) 2011-07-18
DE60138271D1 (de) 2009-05-20
CN1394204A (zh) 2003-01-29
AU767724B2 (en) 2003-11-20
PT2067772E (pt) 2011-07-13
PL214039B1 (pl) 2013-06-28
WO2001056992A2 (en) 2001-08-09
KR101216285B1 (ko) 2012-12-28
SK287217B6 (sk) 2010-03-08
KR20090102882A (ko) 2009-09-30
US20030032800A1 (en) 2003-02-13
CZ20022676A3 (cs) 2002-11-13
KR20080003016A (ko) 2008-01-04
WO2001056992A3 (en) 2002-01-24
NO20023575D0 (no) 2002-07-26
KR100931753B1 (ko) 2009-12-14
CZ301572B6 (cs) 2010-04-21
AU4237301A (en) 2001-08-14
KR20100018069A (ko) 2010-02-16
TWI284638B (en) 2007-08-01
PL217225B1 (pl) 2014-06-30
ES2324900T3 (es) 2009-08-19
EP2067772A2 (de) 2009-06-10
EP2067772A3 (de) 2009-08-19
IL150613A (en) 2010-05-17
KR20080103608A (ko) 2008-11-27
AR079237A2 (es) 2012-01-04
CA2724295C (en) 2011-07-26
HUP0300243A3 (en) 2005-07-28
SI2067772T1 (sl) 2011-08-31
PE20011078A1 (es) 2001-11-16
EP1265868A2 (de) 2002-12-18
ES2363490T3 (es) 2011-08-05
BR0107922A (pt) 2002-10-22
CA2724295A1 (en) 2001-08-09
KR20020071033A (ko) 2002-09-11
ATE427938T1 (de) 2009-04-15
HUP0300243A2 (hu) 2003-06-28
JP4859322B2 (ja) 2012-01-25
CN1721409A (zh) 2006-01-18
AR029442A1 (es) 2003-06-25
DE60144456D1 (de) 2011-05-26
PL392476A1 (pl) 2010-11-22
TR200201655T2 (tr) 2002-11-21
CA2395601A1 (en) 2001-08-09
RU2303591C2 (ru) 2007-07-27
CA2639210A1 (en) 2001-08-09

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