IL148942A0 - C-peptide for the improved production of insulin and insulin analogues - Google Patents

C-peptide for the improved production of insulin and insulin analogues

Info

Publication number
IL148942A0
IL148942A0 IL14894200A IL14894200A IL148942A0 IL 148942 A0 IL148942 A0 IL 148942A0 IL 14894200 A IL14894200 A IL 14894200A IL 14894200 A IL14894200 A IL 14894200A IL 148942 A0 IL148942 A0 IL 148942A0
Authority
IL
Israel
Prior art keywords
insulin
chain
amino acid
human insulin
peptide
Prior art date
Application number
IL14894200A
Other languages
English (en)
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of IL148942A0 publication Critical patent/IL148942A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14894200A 1999-10-02 2000-09-15 C-peptide for the improved production of insulin and insulin analogues IL148942A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19947456A DE19947456A1 (de) 1999-10-02 1999-10-02 C-Peptid zur verbesserten Herstellung von Insulin und Insulinanaloga
PCT/EP2000/009017 WO2001025278A1 (de) 1999-10-02 2000-09-15 C-peptid zur verbesserten herstellung von insulin und insulinanaloga

Publications (1)

Publication Number Publication Date
IL148942A0 true IL148942A0 (en) 2002-09-12

Family

ID=7924253

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14894200A IL148942A0 (en) 1999-10-02 2000-09-15 C-peptide for the improved production of insulin and insulin analogues
IL148942A IL148942A (en) 1999-10-02 2002-03-31 Pre-insulin with C-peptide modified for improved insulin production and insulin analogues

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL148942A IL148942A (en) 1999-10-02 2002-03-31 Pre-insulin with C-peptide modified for improved insulin production and insulin analogues

Country Status (25)

Country Link
US (1) US6534288B1 (no)
EP (1) EP1222207B1 (no)
JP (1) JP4681784B2 (no)
KR (1) KR100823463B1 (no)
CN (1) CN1193042C (no)
AT (1) ATE380196T1 (no)
AU (1) AU778369B2 (no)
BR (2) BR0014464A (no)
CA (1) CA2385857C (no)
CY (1) CY1107860T1 (no)
DE (2) DE19947456A1 (no)
DK (1) DK1222207T3 (no)
ES (1) ES2295054T3 (no)
HK (1) HK1049016B (no)
HU (1) HU228313B1 (no)
IL (2) IL148942A0 (no)
MX (1) MXPA02003103A (no)
NO (1) NO329975B1 (no)
NZ (1) NZ518066A (no)
PL (1) PL203195B1 (no)
PT (1) PT1222207E (no)
SI (1) SI1222207T1 (no)
TW (1) TWI265168B (no)
WO (1) WO2001025278A1 (no)
ZA (1) ZA200202520B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US20050250676A1 (en) * 2001-11-19 2005-11-10 Aventis Pharma Deutschland Gmbh Method of activating insulin receptor substrate-2 to stimulate insulin production
US20040038864A1 (en) * 2002-06-27 2004-02-26 Per Balschmidt Use of dimethyl sulfone as isotonicity agent
DE10235168A1 (de) * 2002-08-01 2004-02-12 Aventis Pharma Deutschland Gmbh Verfahren zur Reinigung von Preproinsulin
ES2369895T3 (es) * 2003-12-03 2011-12-07 Novo Nordisk A/S Insulina monocatenaria.
CN1663960B (zh) * 2004-03-01 2012-07-04 重庆富进生物医药有限公司 高效表达重组人胰岛素原及其类似物的新型c肽
WO2007121318A2 (en) * 2006-04-12 2007-10-25 Emisphere Technologies, Inc. Formulations for delivering insulin
DE102008025007A1 (de) 2008-05-24 2009-11-26 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
DE102008003566A1 (de) 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
DE102008003568A1 (de) 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
DE102008025008A1 (de) 2008-05-24 2009-11-26 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
BRPI0907119A2 (pt) * 2008-01-09 2015-07-14 Sanofi Aventis Deutschland Derivados de insulina tendo um perfil de ação de tempo extremamente retardado
DK2229407T3 (en) 2008-01-09 2017-02-27 Sanofi Aventis Deutschland NEW INSULIN DERIVATIVES WITH EXTREMELY DELAYED TIME / EFFECTS PROFILE
WO2010043566A2 (de) 2008-10-17 2010-04-22 Sanofi-Aventis Deutschland Gmbh Kombination von einem insulin und einem glp-1-agonisten
ES2855146T3 (es) 2009-11-13 2021-09-23 Sanofi Aventis Deutschland Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina
US9707176B2 (en) 2009-11-13 2017-07-18 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist and methionine
PT2611458T (pt) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PT2750699E (pt) 2011-08-29 2015-11-03 Sanofi Aventis Deutschland Acelerómetro pendular
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
TWI780236B (zh) 2013-02-04 2022-10-11 法商賽諾菲公司 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
SG11201604706TA (en) 2014-01-09 2016-07-28 Sanofi Sa Stabilized pharmaceutical formulations of insulin aspart
WO2015104311A1 (en) 2014-01-09 2015-07-16 Sanofi Stabilized glycerol free pharmaceutical formulations of insulin analogues and/or insulin derivatives
CN112957455A (zh) 2014-01-09 2021-06-15 赛诺菲 胰岛素类似物和/或胰岛素衍生物的稳定化药物制剂
CN107206058A (zh) 2014-12-12 2017-09-26 赛诺菲-安万特德国有限公司 甘精胰岛素/利西拉来固定比率配制剂
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH16156A (en) * 1980-03-27 1983-07-18 Lilly Co Eli Process for producing an insulin precursor
US4430266A (en) * 1980-11-28 1984-02-07 Eli Lilly And Company Process for producing an insulin precursor
HRP940432B1 (en) * 1994-08-05 2003-10-31 Pliva Pharm & Chem Works Dna sequences encoding biosynthetic insulin precursors and process for preparation of insulin
ES2218622T3 (es) * 1996-07-26 2004-11-16 Aventis Pharma Deutschland Gmbh Derivados de insulina con actividad de union al zinc incrementada.
DE19726167B4 (de) * 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung

Also Published As

Publication number Publication date
KR20020047209A (ko) 2002-06-21
CA2385857C (en) 2012-05-22
ATE380196T1 (de) 2007-12-15
DK1222207T3 (da) 2008-03-17
JP4681784B2 (ja) 2011-05-11
NO329975B1 (no) 2011-01-31
PL203195B1 (pl) 2009-09-30
HK1049016B (zh) 2005-10-14
NO20021335D0 (no) 2002-03-18
DE19947456A1 (de) 2001-04-05
CA2385857A1 (en) 2001-04-12
EP1222207B1 (de) 2007-12-05
HUP0202755A3 (en) 2005-01-28
AU778369B2 (en) 2004-12-02
CN1377370A (zh) 2002-10-30
IL148942A (en) 2010-02-17
MXPA02003103A (es) 2002-09-30
AU7287700A (en) 2001-05-10
BR0014464A (pt) 2002-06-11
NZ518066A (en) 2004-05-28
HUP0202755A2 (hu) 2002-12-28
HK1049016A1 (en) 2003-04-25
JP2003511018A (ja) 2003-03-25
DE50014830D1 (de) 2008-01-17
SI1222207T1 (sl) 2008-04-30
NO20021335L (no) 2002-06-03
BRPI0014464B8 (pt) 2021-05-25
BRPI0014464B1 (pt) 2018-03-13
PL354078A1 (en) 2003-12-15
ZA200202520B (en) 2002-12-24
TWI265168B (en) 2006-11-01
HU228313B1 (en) 2013-03-28
CY1107860T1 (el) 2013-06-19
KR100823463B1 (ko) 2008-04-21
EP1222207A1 (de) 2002-07-17
CN1193042C (zh) 2005-03-16
US6534288B1 (en) 2003-03-18
WO2001025278A1 (de) 2001-04-12
PT1222207E (pt) 2008-02-11
ES2295054T3 (es) 2008-04-16

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