MA27982A1 - Preparation de peptides somatostatine - Google Patents

Preparation de peptides somatostatine

Info

Publication number
MA27982A1
MA27982A1 MA28779A MA28779A MA27982A1 MA 27982 A1 MA27982 A1 MA 27982A1 MA 28779 A MA28779 A MA 28779A MA 28779 A MA28779 A MA 28779A MA 27982 A1 MA27982 A1 MA 27982A1
Authority
MA
Morocco
Prior art keywords
preparation
somatostatin peptides
somatostatin
peptides
wietfeld
Prior art date
Application number
MA28779A
Other languages
English (en)
Inventor
Heribert Hellstern
Werner Pachinger
Walter Prikoszovich
Bernhard Wietfeld
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA27982A1 publication Critical patent/MA27982A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

" PREPARATION DE PEPTIDES DE SOMATOSTATINE " Invention de : HELLSTERN, Heribert PACHINGER, Werner PRIKOSZOVICH, Walter WIETFELD, Bernhard Il est fourni un procédé pour préparer des analogues de somatostatine cycliques et les intermédiaires linéaires utilisés dans le procédé.
MA28779A 2003-08-08 2006-02-07 Preparation de peptides somatostatine MA27982A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0318682.2A GB0318682D0 (en) 2003-08-08 2003-08-08 Organic compounds

Publications (1)

Publication Number Publication Date
MA27982A1 true MA27982A1 (fr) 2006-07-03

Family

ID=27839906

Family Applications (1)

Application Number Title Priority Date Filing Date
MA28779A MA27982A1 (fr) 2003-08-08 2006-02-07 Preparation de peptides somatostatine

Country Status (35)

Country Link
US (1) US7615609B2 (fr)
EP (1) EP1654280B8 (fr)
JP (1) JP4580928B2 (fr)
KR (1) KR101136633B1 (fr)
CN (2) CN102127155B (fr)
AR (1) AR045327A1 (fr)
AT (1) ATE394424T1 (fr)
AU (1) AU2004262570B2 (fr)
BR (1) BRPI0413437B1 (fr)
CA (1) CA2534224C (fr)
CO (1) CO5660271A2 (fr)
CY (1) CY1108775T1 (fr)
DE (1) DE602004013599D1 (fr)
DK (1) DK1654280T3 (fr)
EC (1) ECSP066352A (fr)
ES (1) ES2307039T3 (fr)
GB (1) GB0318682D0 (fr)
HK (1) HK1090065A1 (fr)
HR (1) HRP20080350T3 (fr)
IL (1) IL173272A (fr)
IS (1) IS2894B (fr)
MA (1) MA27982A1 (fr)
MX (1) MXPA06001525A (fr)
MY (1) MY141731A (fr)
NO (1) NO338367B1 (fr)
NZ (1) NZ544961A (fr)
PE (2) PE20091210A1 (fr)
PL (1) PL1654280T3 (fr)
PT (1) PT1654280E (fr)
RU (1) RU2360921C2 (fr)
SI (1) SI1654280T1 (fr)
TN (1) TNSN06045A1 (fr)
TW (1) TWI345570B (fr)
WO (1) WO2005014624A2 (fr)
ZA (1) ZA200600584B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2225271B1 (fr) * 2007-12-03 2013-07-31 ITALFARMACO S.p.A. Nouveaux analogues non sélectifs de somatostatine
EP2067786A1 (fr) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Nouveaux analogues non sélectifs de somatostatine
ES2522167T3 (es) 2010-01-05 2014-11-13 National Dong Hwa University Formulación anticancerosa
CN103467575B (zh) * 2013-08-22 2016-03-02 深圳翰宇药业股份有限公司 一种帕西瑞肽的制备方法
CN103641894B (zh) * 2013-12-06 2015-10-28 深圳翰宇药业股份有限公司 一种治疗库欣病的多肽药物的制备方法
EP3233899B1 (fr) * 2014-12-19 2020-06-24 Auro Peptides LTD Procédé de préparation de pasiréotide
CN106188231B (zh) * 2015-05-25 2021-10-22 中国医学科学院药物研究所 帕西瑞肽五肽中间体的合成与应用
CN114621326B (zh) * 2020-12-10 2023-12-26 武汉武药科技有限公司 门冬氨酸帕瑞肽及其中间体和其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3303345A1 (de) 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Cyclische peptide mit somatostatin-wirkung
EP0255224A3 (fr) 1986-06-30 1990-04-18 Merck & Co. Inc. Analogues cycliques et pontés cycliques du somatostatin utilisable comme médicaments analgésiques
US5811512A (en) 1991-08-22 1998-09-22 The Trustees Of The University Of Pennsylvania Non-peptide peptidomimetics and related cyclic hexapeptides
DE69426673T2 (de) 1993-06-23 2001-09-20 Diatide Inc Radiomarkierte somatostatin derivate zur abbildung und zur therapeutischen verwendung
US5770687A (en) 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
GB0018891D0 (en) * 2000-08-01 2000-09-20 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
HRP20080350T3 (en) 2008-08-31
KR20060070541A (ko) 2006-06-23
US20060258838A1 (en) 2006-11-16
CY1108775T1 (el) 2014-04-09
EP1654280B1 (fr) 2008-05-07
TNSN06045A1 (en) 2007-10-03
KR101136633B1 (ko) 2012-04-18
HK1090065A1 (en) 2006-12-15
RU2360921C2 (ru) 2009-07-10
CO5660271A2 (es) 2006-07-31
BRPI0413437B1 (pt) 2017-12-12
CN102127155B (zh) 2013-11-27
EP1654280B8 (fr) 2008-08-13
ES2307039T3 (es) 2008-11-16
ECSP066352A (es) 2006-08-30
ZA200600584B (en) 2006-12-27
EP1654280A2 (fr) 2006-05-10
PL1654280T3 (pl) 2008-10-31
MY141731A (en) 2010-06-15
IL173272A0 (en) 2006-06-11
IL173272A (en) 2012-03-29
WO2005014624A3 (fr) 2005-09-22
RU2006106721A (ru) 2007-09-20
MXPA06001525A (es) 2006-05-15
AR045327A1 (es) 2005-10-26
CA2534224A1 (fr) 2005-02-17
DK1654280T3 (da) 2008-09-29
IS2894B (is) 2014-09-15
IS8338A (is) 2006-03-02
TW200524955A (en) 2005-08-01
PE20091210A1 (es) 2009-09-07
TWI345570B (en) 2011-07-21
US7615609B2 (en) 2009-11-10
CN1832962A (zh) 2006-09-13
DE602004013599D1 (de) 2008-06-19
AU2004262570B2 (en) 2008-06-19
BRPI0413437A (pt) 2006-10-10
ATE394424T1 (de) 2008-05-15
NO338367B1 (no) 2016-08-15
NO20061125L (no) 2006-05-08
WO2005014624A2 (fr) 2005-02-17
JP2007526899A (ja) 2007-09-20
AU2004262570A1 (en) 2005-02-17
CA2534224C (fr) 2012-03-27
PE20050356A1 (es) 2005-06-17
SI1654280T1 (sl) 2008-10-31
PT1654280E (pt) 2008-08-18
JP4580928B2 (ja) 2010-11-17
CN102127155A (zh) 2011-07-20
NZ544961A (en) 2008-08-29
GB0318682D0 (en) 2003-09-10

Similar Documents

Publication Publication Date Title
MA27982A1 (fr) Preparation de peptides somatostatine
EP2039699A3 (fr) Procédés d'extraction pour purifier le sucralose
TWI265168B (en) C peptide for improved preparation of insulin and insulin analogs
HUP0100928A2 (hu) Humán inzulin B láncának részletét tartalmazó peptidanalógok, ezeket tartalmazó gyógyászati készítmények és alkalmazásuk
MXPA03007678A (es) Composicion farmaceutica oral de proxetil cefpodoxima.
EP0249224A3 (fr) Agent antihypertensif
TW200635919A (en) Novel processes for the preparation of CGRP-receptor antagonists and intermediates thereof
YU7804A (sh) Stabilni polimorf flibanserina,postupak za njegovo dobijanje u industrijskim razmerama i njegova primena za pripremanje lekova
CY1110487T1 (el) Χρηση της lh σε ελεγχομενη υπερδιεγερση των ωοθηκων
SG144736A1 (en) Synthesis of temozolomide and analogs
PT87537A (pt) Process for the preparation of cyclic anticoagulant peptides
MA27862A1 (fr) Composition pharmaceutique
SG143062A1 (en) Synthesis of temozolomide and analogs
ES8700272A1 (es) Procedimiento para la preparacion y purificacion de peptidos
ATE407127T1 (de) Verfahren zur herstellung von beraprost und dessen salzen
TR200503401T1 (tr) Kuetiapin (Quetiapine) Fumarat'ın yeni polimorfları
EP2279741A3 (fr) Caprolactames et leur utilisation comme agents anti-inflammatoires
MXPA04001986A (es) Composiciones y metodos para el tratamiento de enfermedades relacionadas a la inmunidad.
DE60224884D1 (de) Verfahren zur herstellung von 3, 3', 6, 6'-tetraalkylen-2, 2'-biphenolen und 3, 3', 6, 6'-tetraalkylen-5, 5'-dihalo-2, 2' biphenolen
EP1199308A3 (fr) Procédé pour la préparation d'intermédiaires de l'imidazodiazépine
DE602004031129D1 (de) Verfahren zur herstellung von quetiapin
DE69939751D1 (de) Verfahren zur Herstellung von S-Aryl-Cystein
DE69814420D1 (de) Stereoselektive verfahren zur herstellung von gabapentinanalogen
SE9800865D0 (sv) New Process
MXPA05008108A (es) Exo-(2r)(+))-2-amino-7-azabiciclo[2.2.1]heptan-7-carboxilato de terc-butilo, compuestos intermedios y procedimiento para prepararlos y aislarlos.