ATE394424T1 - Herstellung von somatostatinpeptiden - Google Patents

Herstellung von somatostatinpeptiden

Info

Publication number
ATE394424T1
ATE394424T1 AT04763881T AT04763881T ATE394424T1 AT E394424 T1 ATE394424 T1 AT E394424T1 AT 04763881 T AT04763881 T AT 04763881T AT 04763881 T AT04763881 T AT 04763881T AT E394424 T1 ATE394424 T1 AT E394424T1
Authority
AT
Austria
Prior art keywords
preparation
somatostatin peptides
somatostatin
peptides
Prior art date
Application number
AT04763881T
Other languages
English (en)
Inventor
Heribert Hellstern
Werner Pachinger
Walter Prikoszovich
Bernhard Wietfeld
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE394424T1 publication Critical patent/ATE394424T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT04763881T 2003-08-08 2004-08-06 Herstellung von somatostatinpeptiden ATE394424T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0318682.2A GB0318682D0 (en) 2003-08-08 2003-08-08 Organic compounds

Publications (1)

Publication Number Publication Date
ATE394424T1 true ATE394424T1 (de) 2008-05-15

Family

ID=27839906

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04763881T ATE394424T1 (de) 2003-08-08 2004-08-06 Herstellung von somatostatinpeptiden

Country Status (35)

Country Link
US (1) US7615609B2 (de)
EP (1) EP1654280B8 (de)
JP (1) JP4580928B2 (de)
KR (1) KR101136633B1 (de)
CN (2) CN1832962A (de)
AR (1) AR045327A1 (de)
AT (1) ATE394424T1 (de)
AU (1) AU2004262570B2 (de)
BR (1) BRPI0413437B1 (de)
CA (1) CA2534224C (de)
CO (1) CO5660271A2 (de)
CY (1) CY1108775T1 (de)
DE (1) DE602004013599D1 (de)
DK (1) DK1654280T3 (de)
EC (1) ECSP066352A (de)
ES (1) ES2307039T3 (de)
GB (1) GB0318682D0 (de)
HK (1) HK1090065A1 (de)
HR (1) HRP20080350T3 (de)
IL (1) IL173272A (de)
IS (1) IS2894B (de)
MA (1) MA27982A1 (de)
MX (1) MXPA06001525A (de)
MY (1) MY141731A (de)
NO (1) NO338367B1 (de)
NZ (1) NZ544961A (de)
PE (2) PE20050356A1 (de)
PL (1) PL1654280T3 (de)
PT (1) PT1654280E (de)
RU (1) RU2360921C2 (de)
SI (1) SI1654280T1 (de)
TN (1) TNSN06045A1 (de)
TW (1) TWI345570B (de)
WO (1) WO2005014624A2 (de)
ZA (1) ZA200600584B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5331817B2 (ja) * 2007-12-03 2013-10-30 イタルファルマコ ソシエタ ペル アチオニ 新規な非選択的ソマトスタチン類似体
EP2067786A1 (de) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Neue nichtselektive Analoga von Somatostatin
ES2522167T3 (es) 2010-01-05 2014-11-13 National Dong Hwa University Formulación anticancerosa
CN103467575B (zh) * 2013-08-22 2016-03-02 深圳翰宇药业股份有限公司 一种帕西瑞肽的制备方法
CN103641894B (zh) * 2013-12-06 2015-10-28 深圳翰宇药业股份有限公司 一种治疗库欣病的多肽药物的制备方法
EP3233899B1 (de) * 2014-12-19 2020-06-24 Auro Peptides LTD Verfahren zur herstellung von pasireotid
CN106188231B (zh) * 2015-05-25 2021-10-22 中国医学科学院药物研究所 帕西瑞肽五肽中间体的合成与应用
CN114621326B (zh) * 2020-12-10 2023-12-26 武汉武药科技有限公司 门冬氨酸帕瑞肽及其中间体和其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3303345A1 (de) * 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Cyclische peptide mit somatostatin-wirkung
EP0255224A3 (de) 1986-06-30 1990-04-18 Merck & Co. Inc. Cyclische und verbrückt cyclische Analoge von Somatostatin, verwendbar als analgetische Arzneimittel
US5811512A (en) 1991-08-22 1998-09-22 The Trustees Of The University Of Pennsylvania Non-peptide peptidomimetics and related cyclic hexapeptides
SG48977A1 (en) * 1993-06-23 1998-05-18 Diatide Inc Radiolabeled peptides
US5770687A (en) 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
GB0018891D0 (en) * 2000-08-01 2000-09-20 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
CN1832962A (zh) 2006-09-13
CA2534224A1 (en) 2005-02-17
TNSN06045A1 (en) 2007-10-03
HK1090065A1 (en) 2006-12-15
CN102127155B (zh) 2013-11-27
BRPI0413437A (pt) 2006-10-10
NZ544961A (en) 2008-08-29
PT1654280E (pt) 2008-08-18
RU2360921C2 (ru) 2009-07-10
KR20060070541A (ko) 2006-06-23
EP1654280A2 (de) 2006-05-10
MY141731A (en) 2010-06-15
CY1108775T1 (el) 2014-04-09
MXPA06001525A (es) 2006-05-15
US7615609B2 (en) 2009-11-10
AR045327A1 (es) 2005-10-26
PL1654280T3 (pl) 2008-10-31
PE20050356A1 (es) 2005-06-17
KR101136633B1 (ko) 2012-04-18
MA27982A1 (fr) 2006-07-03
WO2005014624A3 (en) 2005-09-22
IS2894B (is) 2014-09-15
TW200524955A (en) 2005-08-01
DK1654280T3 (da) 2008-09-29
SI1654280T1 (sl) 2008-10-31
NO20061125L (no) 2006-05-08
CO5660271A2 (es) 2006-07-31
AU2004262570A1 (en) 2005-02-17
IL173272A (en) 2012-03-29
IL173272A0 (en) 2006-06-11
ZA200600584B (en) 2006-12-27
ES2307039T3 (es) 2008-11-16
CN102127155A (zh) 2011-07-20
BRPI0413437B1 (pt) 2017-12-12
AU2004262570B2 (en) 2008-06-19
JP2007526899A (ja) 2007-09-20
HRP20080350T3 (en) 2008-08-31
WO2005014624A2 (en) 2005-02-17
EP1654280B8 (de) 2008-08-13
EP1654280B1 (de) 2008-05-07
GB0318682D0 (en) 2003-09-10
RU2006106721A (ru) 2007-09-20
DE602004013599D1 (de) 2008-06-19
JP4580928B2 (ja) 2010-11-17
IS8338A (is) 2006-03-02
US20060258838A1 (en) 2006-11-16
TWI345570B (en) 2011-07-21
NO338367B1 (no) 2016-08-15
ECSP066352A (es) 2006-08-30
CA2534224C (en) 2012-03-27
PE20091210A1 (es) 2009-09-07

Similar Documents

Publication Publication Date Title
DE60217126D1 (de) Herstellung von aminopyrimidinverbindungen
CY2015011I1 (el) Μικροσωματιδια που περιλαμβανουν αναλογα σωματοστατινης
NO20050132D0 (no) Vaksinesammensetning
DK1478328T3 (da) Bioaktive keratinpeptider
DE50100160D1 (de) Herstellung von aminofunktionellen Siloxanen
NO20033078L (no) Hydrolysat av fiskeprotein
DE50303749D1 (de) Verfahren zur herstellung von phthalocyaninpigmentzubereitungen
DE60334857D1 (de) Kosmetische zubereitung
NO20044916L (no) Preparater av sulfinylacetamid
DE60304223D1 (de) Herstellung von metallamid-komplexen
DE602004030605D1 (de) Herstellung von titanoxid
IS8338A (is) Framleiðsla sómatóstatínpeptíða
DE602004015504D1 (de) Von injektionspräparaten
DE50304610D1 (de) Herstellung strukturierter hartchromschichten
DE60142051D1 (de) Herstellung von perfluorolefinen
DE60333439D1 (de) Herstellung von olefinen
DE602004003529D1 (de) Herstellung von Organohalosilanen
DE602004022046D1 (de) Herstellung von kleinen teilchen
DE50307976D1 (de) Lü fter
DE60307022D1 (de) Herstellung von Organohalosilanen
NO20043948L (no) Fremstilling av olefiner
DK1648934T3 (da) Farmaceutisk sammensætning indeholdende cycliske somatostatinanaloger
DK1625148T3 (da) Peptidkompleks
DE602004008992D1 (de) Herstellung von verzweigten Tetrasiloxanen
DE602004024640D1 (de) Reinigung von titantetrachlorid

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1654280

Country of ref document: EP