DK1222207T3 - C-peptid til forbedret fremstilling af insulin og insulinanaloge - Google Patents

C-peptid til forbedret fremstilling af insulin og insulinanaloge

Info

Publication number
DK1222207T3
DK1222207T3 DK00960664T DK00960664T DK1222207T3 DK 1222207 T3 DK1222207 T3 DK 1222207T3 DK 00960664 T DK00960664 T DK 00960664T DK 00960664 T DK00960664 T DK 00960664T DK 1222207 T3 DK1222207 T3 DK 1222207T3
Authority
DK
Denmark
Prior art keywords
insulin
chain
amino acid
human insulin
peptide
Prior art date
Application number
DK00960664T
Other languages
English (en)
Inventor
Paul Habermann
Johannes Meiwes
Gerhard Seipke
Johann Ertl
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1222207T3 publication Critical patent/DK1222207T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK00960664T 1999-10-02 2000-09-15 C-peptid til forbedret fremstilling af insulin og insulinanaloge DK1222207T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19947456A DE19947456A1 (de) 1999-10-02 1999-10-02 C-Peptid zur verbesserten Herstellung von Insulin und Insulinanaloga
PCT/EP2000/009017 WO2001025278A1 (de) 1999-10-02 2000-09-15 C-peptid zur verbesserten herstellung von insulin und insulinanaloga

Publications (1)

Publication Number Publication Date
DK1222207T3 true DK1222207T3 (da) 2008-03-17

Family

ID=7924253

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00960664T DK1222207T3 (da) 1999-10-02 2000-09-15 C-peptid til forbedret fremstilling af insulin og insulinanaloge

Country Status (25)

Country Link
US (1) US6534288B1 (da)
EP (1) EP1222207B1 (da)
JP (1) JP4681784B2 (da)
KR (1) KR100823463B1 (da)
CN (1) CN1193042C (da)
AT (1) ATE380196T1 (da)
AU (1) AU778369B2 (da)
BR (2) BR0014464A (da)
CA (1) CA2385857C (da)
CY (1) CY1107860T1 (da)
DE (2) DE19947456A1 (da)
DK (1) DK1222207T3 (da)
ES (1) ES2295054T3 (da)
HK (1) HK1049016B (da)
HU (1) HU228313B1 (da)
IL (2) IL148942A0 (da)
MX (1) MXPA02003103A (da)
NO (1) NO329975B1 (da)
NZ (1) NZ518066A (da)
PL (1) PL203195B1 (da)
PT (1) PT1222207E (da)
SI (1) SI1222207T1 (da)
TW (1) TWI265168B (da)
WO (1) WO2001025278A1 (da)
ZA (1) ZA200202520B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
US20050250676A1 (en) * 2001-11-19 2005-11-10 Aventis Pharma Deutschland Gmbh Method of activating insulin receptor substrate-2 to stimulate insulin production
US20040038864A1 (en) * 2002-06-27 2004-02-26 Per Balschmidt Use of dimethyl sulfone as isotonicity agent
DE10235168A1 (de) * 2002-08-01 2004-02-12 Aventis Pharma Deutschland Gmbh Verfahren zur Reinigung von Preproinsulin
CN102816228A (zh) * 2003-12-03 2012-12-12 诺和诺德公司 单链胰岛素
CN1663960B (zh) * 2004-03-01 2012-07-04 重庆富进生物医药有限公司 高效表达重组人胰岛素原及其类似物的新型c肽
US8927015B2 (en) * 2006-04-12 2015-01-06 Emisphere Technologies, Inc. Formulations for delivering insulin
DE102008025007A1 (de) 2008-05-24 2009-11-26 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
DE102008003566A1 (de) 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
DE102008025008A1 (de) 2008-05-24 2009-11-26 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
DE102008003568A1 (de) 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
BRPI0907371A2 (pt) * 2008-01-09 2015-11-24 Sanofi Aventis Deutschland derivados de insulina com um perfil de tempo-ação muito retardado
NZ586589A (en) * 2008-01-09 2012-04-27 Sanofi Aventis Deutschland Novel insulin analogues having an extremely delayed time-action profile
BR122013025625B1 (pt) 2008-10-17 2021-08-03 Sanofi-Aventis Deutschland Gmbh Composição farmacêutica, seu uso e método de preparação da mesma, kit e dispositivo
SI2498801T1 (en) 2009-11-13 2018-06-29 Sanofi-Aventis Deutschland Gmbh A pharmaceutical composition containing desPro36Exendin-4 (1-39) -Lys6-NH2 and methionine
ES2676373T3 (es) 2009-11-13 2018-07-19 Sanofi-Aventis Deutschland Gmbh Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina
RS55378B1 (sr) 2010-08-30 2017-03-31 Sanofi Aventis Deutschland Upotreba ave0010 za proizvodnju leka za tretman diabetes mellitus tipa 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
US9408893B2 (en) 2011-08-29 2016-08-09 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for use in glycemic control in diabetes type 2 patients
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
TWI780236B (zh) 2013-02-04 2022-10-11 法商賽諾菲公司 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
US9839692B2 (en) 2014-01-09 2017-12-12 Sanofi Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives
RU2016132386A (ru) 2014-01-09 2018-02-14 Санофи Стабилизированные фармацевтические составы без глицерина на основе инсулиновых аналогов и/или инсулиновых производных
KR20160101195A (ko) 2014-01-09 2016-08-24 사노피 인슐린 아스파트의 안정화된 약제학적 제형
LT3229828T (lt) 2014-12-12 2023-06-12 Sanofi-Aventis Deutschland Gmbh Insulino glargino/liksisenatido fiksuoto santykio kompozicija
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH16156A (en) * 1980-03-27 1983-07-18 Lilly Co Eli Process for producing an insulin precursor
US4430266A (en) * 1980-11-28 1984-02-07 Eli Lilly And Company Process for producing an insulin precursor
HRP940432B1 (en) * 1994-08-05 2003-10-31 Pliva Pharm & Chem Works Dna sequences encoding biosynthetic insulin precursors and process for preparation of insulin
ES2218622T3 (es) * 1996-07-26 2004-11-16 Aventis Pharma Deutschland Gmbh Derivados de insulina con actividad de union al zinc incrementada.
DE19726167B4 (de) * 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung

Also Published As

Publication number Publication date
NO20021335D0 (no) 2002-03-18
WO2001025278A1 (de) 2001-04-12
NO329975B1 (no) 2011-01-31
JP4681784B2 (ja) 2011-05-11
PL203195B1 (pl) 2009-09-30
KR100823463B1 (ko) 2008-04-21
TWI265168B (en) 2006-11-01
IL148942A0 (en) 2002-09-12
MXPA02003103A (es) 2002-09-30
AU7287700A (en) 2001-05-10
US6534288B1 (en) 2003-03-18
ES2295054T3 (es) 2008-04-16
HUP0202755A3 (en) 2005-01-28
EP1222207A1 (de) 2002-07-17
CY1107860T1 (el) 2013-06-19
CA2385857C (en) 2012-05-22
PT1222207E (pt) 2008-02-11
HUP0202755A2 (hu) 2002-12-28
DE50014830D1 (de) 2008-01-17
KR20020047209A (ko) 2002-06-21
DE19947456A1 (de) 2001-04-05
BRPI0014464B8 (pt) 2021-05-25
AU778369B2 (en) 2004-12-02
CN1193042C (zh) 2005-03-16
EP1222207B1 (de) 2007-12-05
BRPI0014464B1 (pt) 2018-03-13
IL148942A (en) 2010-02-17
CN1377370A (zh) 2002-10-30
HK1049016A1 (en) 2003-04-25
JP2003511018A (ja) 2003-03-25
HU228313B1 (en) 2013-03-28
ATE380196T1 (de) 2007-12-15
CA2385857A1 (en) 2001-04-12
BR0014464A (pt) 2002-06-11
SI1222207T1 (sl) 2008-04-30
NZ518066A (en) 2004-05-28
NO20021335L (no) 2002-06-03
PL354078A1 (en) 2003-12-15
HK1049016B (zh) 2005-10-14
ZA200202520B (en) 2002-12-24

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