IL143063A0 - Cross-linked hyaluronic acids and medical uses thereof - Google Patents

Cross-linked hyaluronic acids and medical uses thereof

Info

Publication number
IL143063A0
IL143063A0 IL14306399A IL14306399A IL143063A0 IL 143063 A0 IL143063 A0 IL 143063A0 IL 14306399 A IL14306399 A IL 14306399A IL 14306399 A IL14306399 A IL 14306399A IL 143063 A0 IL143063 A0 IL 143063A0
Authority
IL
Israel
Prior art keywords
cross
linked hyaluronic
hyaluronic acids
medical uses
linked
Prior art date
Application number
IL14306399A
Other languages
English (en)
Original Assignee
Aquisitio S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11381033&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL143063(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aquisitio S P A filed Critical Aquisitio S P A
Publication of IL143063A0 publication Critical patent/IL143063A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
IL14306399A 1998-11-11 1999-11-08 Cross-linked hyaluronic acids and medical uses thereof IL143063A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002440A IT1303735B1 (it) 1998-11-11 1998-11-11 Acidi ialuronici reticolati e loro usi medici.
PCT/EP1999/008481 WO2000027887A2 (en) 1998-11-11 1999-11-08 Cross-linked hyaluronic acids and medical uses thereof

Publications (1)

Publication Number Publication Date
IL143063A0 true IL143063A0 (en) 2002-04-21

Family

ID=11381033

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14306399A IL143063A0 (en) 1998-11-11 1999-11-08 Cross-linked hyaluronic acids and medical uses thereof

Country Status (24)

Country Link
US (1) US6831172B1 (cs)
EP (1) EP1144459B2 (cs)
JP (1) JP2002529550A (cs)
KR (1) KR100674177B1 (cs)
CN (1) CN1131241C (cs)
AT (1) ATE225371T1 (cs)
AU (1) AU757102B2 (cs)
BR (1) BR9915235A (cs)
CA (1) CA2350667A1 (cs)
CZ (1) CZ296842B6 (cs)
DE (1) DE69903351T3 (cs)
DK (1) DK1144459T4 (cs)
ES (1) ES2184521T5 (cs)
HK (1) HK1041011B (cs)
HU (1) HU229668B1 (cs)
IL (1) IL143063A0 (cs)
IT (1) IT1303735B1 (cs)
NO (1) NO20012315L (cs)
NZ (1) NZ511306A (cs)
PT (1) PT1144459E (cs)
RU (1) RU2230752C2 (cs)
TR (1) TR200101324T2 (cs)
WO (1) WO2000027887A2 (cs)
ZA (1) ZA200103799B (cs)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD980037A1 (it) * 1998-02-25 1999-08-25 Fidia Advanced Biopolymers Srl Acido ialuronico solfatato e i suoi derivati legati covalentemente a polimeri sintetici pe la preparazione di biomateriali e per il rivesti
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US6307487B1 (en) 1998-09-23 2001-10-23 Digital Fountain, Inc. Information additive code generator and decoder for communication systems
US7068729B2 (en) 2001-12-21 2006-06-27 Digital Fountain, Inc. Multi-stage code generator and decoder for communication systems
IT1303738B1 (it) * 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.
DK1140198T3 (da) 1999-01-13 2008-03-10 Alchemia Oncology Pty Ltd Anvendelse af hyaluronan til fremstilling af et lægemiddel til forögelse af cytotoksiske lægemidlers virkningsgrad
KR100338179B1 (ko) * 2000-05-08 2002-05-24 김범철 안질환 치료용 약물 전달을 위한 그래프트 중합체 및 그제조방법
AUPQ879500A0 (en) * 2000-07-14 2000-08-10 Meditech Research Limited Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease
US9066919B2 (en) * 2000-07-14 2015-06-30 Alchemia Oncology Pty Limited Hyaluronan as a chemo-sensitizer in the treatment of cancer
KR100375299B1 (ko) * 2000-10-10 2003-03-10 주식회사 엘지생명과학 히알루론산의 가교결합형 아마이드 유도체와 이의 제조방법
US7335383B2 (en) 2001-01-16 2008-02-26 The Regents Of The University Of Michigan Generation of nitric oxide in vivo from nitrite, nitrate or nitrosothiols endogenous in blood
US7128904B2 (en) 2001-01-16 2006-10-31 The Regents Of The University Of Michigan Material containing metal ion ligand complex producing nitric oxide in contact with blood
JP4430867B2 (ja) * 2001-01-16 2010-03-10 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 基材／血液境界面で、ｉｎｓｉｔｕで、生体触媒により生じる、生体疑似的な（ｂｉｏｍｉｍｅｔｉｃ）一酸化窒素の生成
EP1427447A4 (en) * 2001-08-27 2007-05-23 Alchemia Oncology Ltd IMPROVED THERAPEUTIC PROTOCOLS
US9240810B2 (en) 2002-06-11 2016-01-19 Digital Fountain, Inc. Systems and processes for decoding chain reaction codes through inactivation
KR20040009891A (ko) * 2002-07-26 2004-01-31 주식회사 엘지생명과학 히알루론산의 유도체 겔 및 그 제조방법
US6909383B2 (en) 2002-10-05 2005-06-21 Digital Fountain, Inc. Systematic encoding and decoding of chain reaction codes
JP2006503657A (ja) * 2002-10-25 2006-02-02 エッセンシア・バイオシステムズ・インコーポレイテッド 亜鉛を用いる埋め込み可能な医療装置
FR2850282B1 (fr) 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
WO2004081055A1 (ja) * 2003-02-21 2004-09-23 Terumo Kabushiki Kaisha 架橋性多糖誘導体、その製造方法、架橋性多糖組成物および医療用処置材
JP2004262777A (ja) * 2003-02-27 2004-09-24 Shiseido Co Ltd アセチル化ヒアルロン酸含有眼用医薬組成物
EP1610838A1 (en) * 2003-04-04 2006-01-04 Bayco Tech Limited Vascular stent
US7139960B2 (en) 2003-10-06 2006-11-21 Digital Fountain, Inc. Error-correcting multi-stage code generator and decoder for communication systems having single transmitters or multiple transmitters
JP4511470B2 (ja) 2003-10-29 2010-07-28 帝人株式会社 ヒアルロン酸化合物、そのハイドロゲルおよび関節軟骨損傷治療用材料
US20090148527A1 (en) * 2007-12-07 2009-06-11 Robinson Michael R Intraocular formulation
CN101019326B (zh) 2004-05-07 2013-02-27 数字方敦股份有限公司 文件下载和流系统
ITMI20041373A1 (it) 2004-07-09 2004-10-09 Lima Lto S P A N-metil-ammidi di carbossimetilcellulosa acido alginico o carbossimetalamido
EP1790665B1 (en) * 2004-09-07 2014-11-05 Chugai Seiyaku Kabushiki Kaisha Process for producing water-soluble modified hyaluronic acid
WO2006051950A1 (ja) * 2004-11-15 2006-05-18 Shiseido Co., Ltd. 架橋ヒアルロン酸ゲルの製造方法
DK1817347T3 (en) * 2004-11-24 2017-08-14 Albumedix As Process for Crosslinking Hyaluronic Acid with Divinyl Sulfone
CN101133102A (zh) * 2004-12-30 2008-02-27 诺维信生物聚合物公司 与α-羟酸的聚合物连接的透明质酸
ITPD20050056A1 (it) 2005-03-02 2006-09-03 Fidia Farmaceutici Derivati ammidici del'acido ialuronico in osteoartrosi
TW200643033A (en) * 2005-03-08 2006-12-16 Chugai Pharmaceutical Co Ltd Conjugate of water-soluble modified hyaluronic acid and glp-1 analogue
US7676735B2 (en) 2005-06-10 2010-03-09 Digital Fountain Inc. Forward error-correcting (FEC) coding and streaming
JP5465431B2 (ja) 2005-07-27 2014-04-09 アルケミア オンコロジー ピーティーワイ リミテッド ヒアルロナンを用いる治療プロトコル
US8623354B2 (en) 2005-09-07 2014-01-07 Alchemia Oncology Pty Limited Therapeutic compositions comprising hyaluronan and therapeutic antibodies as well as methods of treatment
US7879818B2 (en) * 2005-12-23 2011-02-01 Janos Borbely Hyaluronic acid-based cross-linked nanoparticles
KR100737954B1 (ko) * 2006-01-03 2007-07-13 고려대학교 산학협력단 조직재생을 위한 히알루론산-기초된 주사형 하이드로겔
CN101686107B (zh) 2006-02-13 2014-08-13 数字方敦股份有限公司 使用可变fec开销和保护周期的流送和缓冲
US9270414B2 (en) 2006-02-21 2016-02-23 Digital Fountain, Inc. Multiple-field based code generator and decoder for communications systems
US20100273734A1 (en) * 2006-02-28 2010-10-28 Novozymes Biopolymer A/S Derivatives of Hyaluronic Acids
US7674781B2 (en) * 2006-04-28 2010-03-09 Heather Sheardown Hyaluronic acid-retaining polymers
WO2007134196A2 (en) 2006-05-10 2007-11-22 Digital Fountain, Inc. Code generator and decoder using hybrid codes
US9178535B2 (en) 2006-06-09 2015-11-03 Digital Fountain, Inc. Dynamic stream interleaving and sub-stream based delivery
US9380096B2 (en) 2006-06-09 2016-06-28 Qualcomm Incorporated Enhanced block-request streaming system for handling low-latency streaming
US9432433B2 (en) 2006-06-09 2016-08-30 Qualcomm Incorporated Enhanced block-request streaming system using signaling or block creation
US9209934B2 (en) 2006-06-09 2015-12-08 Qualcomm Incorporated Enhanced block-request streaming using cooperative parallel HTTP and forward error correction
US9386064B2 (en) 2006-06-09 2016-07-05 Qualcomm Incorporated Enhanced block-request streaming using URL templates and construction rules
US9419749B2 (en) 2009-08-19 2016-08-16 Qualcomm Incorporated Methods and apparatus employing FEC codes with permanent inactivation of symbols for encoding and decoding processes
CN101501075B (zh) * 2006-08-04 2013-07-10 诺维信生物制药丹麦公司 支化透明质酸和制造方法
US20080070993A1 (en) * 2006-09-07 2008-03-20 Janos Borbely Additives for cosmetic products and the like
FR2909285A1 (fr) * 2006-12-01 2008-06-06 Anteis Sa "utilisation d'un gel anti-adhesif et anti fibrotique"
FR2909560B1 (fr) * 2006-12-06 2012-12-28 Fabre Pierre Dermo Cosmetique Gel d'acide hyaluronique pour injection intradermique
JP2008255061A (ja) * 2007-04-06 2008-10-23 Shiseido Co Ltd 可溶性架橋ヒアルロン酸含有眼用組成物
WO2009012367A1 (en) * 2007-07-18 2009-01-22 Aesthetic Science Composition and method of use for soft tissue augmentation/drug delivery
ES2429794T3 (es) * 2007-08-15 2013-11-15 Metamorefix Péptidos y composiciones farmacéuticas para tratar tejido conjuntivo
AU2008298602A1 (en) 2007-09-12 2009-03-19 Digital Fountain, Inc. Generating and communicating source identification information to enable reliable communications
KR101594552B1 (ko) 2008-04-04 2016-02-17 유니버시티 오브 유타 리서치 파운데이션 알킬화된 반합성 글리코사미노글리코산 에테르 및 이의 제조 및 사용 방법
EP2280739B1 (en) * 2008-06-03 2012-07-04 Actamax Surgical Materials LLC A tissue coating for preventing undesired tissue-to-tissue adhesions
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
CN102112496A (zh) * 2008-08-05 2011-06-29 帝人株式会社 水凝胶
US20100104654A1 (en) 2008-10-27 2010-04-29 Allergan, Inc. Prostaglandin and prostamide drug delivery systems and intraocular therapeutic uses thereof
FR2938187B1 (fr) * 2008-11-07 2012-08-17 Anteis Sa Composition injectable a base d'acide hyaluronique ou l'un de ses sels, de polyols et de lidocaine, sterilisee a la chaleur
US9281847B2 (en) 2009-02-27 2016-03-08 Qualcomm Incorporated Mobile reception of digital video broadcasting—terrestrial services
US9288010B2 (en) 2009-08-19 2016-03-15 Qualcomm Incorporated Universal file delivery methods for providing unequal error protection and bundled file delivery services
IT1395392B1 (it) * 2009-08-27 2012-09-14 Fidia Farmaceutici Geli viscoelastici come nuovi filler
US9917874B2 (en) 2009-09-22 2018-03-13 Qualcomm Incorporated Enhanced block-request streaming using block partitioning or request controls for improved client-side handling
JP5604072B2 (ja) * 2009-09-28 2014-10-08 テルモ株式会社 活性エステル化多糖およびその製造方法
FR2954945B1 (fr) * 2010-01-04 2012-01-06 Oreal Composition cosmetique ou dermatologique, procede de traitement cosmetique et derive d'acide hyaluronique
US9225961B2 (en) 2010-05-13 2015-12-29 Qualcomm Incorporated Frame packing for asymmetric stereo video
JP2013530785A (ja) * 2010-07-12 2013-08-01 シン・プーン・ファーマシューティカル・カンパニー・リミテッド 組織増大用充填組成物
US9596447B2 (en) 2010-07-21 2017-03-14 Qualcomm Incorporated Providing frame packing type information for video coding
US9456015B2 (en) 2010-08-10 2016-09-27 Qualcomm Incorporated Representation groups for network streaming of coded multimedia data
US8958375B2 (en) 2011-02-11 2015-02-17 Qualcomm Incorporated Framing for an improved radio link protocol including FEC
US9270299B2 (en) 2011-02-11 2016-02-23 Qualcomm Incorporated Encoding and decoding using elastic codes with flexible source block mapping
EP2688402B1 (en) 2011-03-23 2018-10-24 University of Utah Research Foundation Means for treating or preventing urological inflammation
RU2477155C2 (ru) * 2011-04-27 2013-03-10 Закрытое акционерное общество "Патент-Фарм" Способ лечения андрогенетической алопеции
US9253233B2 (en) 2011-08-31 2016-02-02 Qualcomm Incorporated Switch signaling methods providing improved switching between representations for adaptive HTTP streaming
US9843844B2 (en) 2011-10-05 2017-12-12 Qualcomm Incorporated Network streaming of media data
CZ303879B6 (cs) * 2012-02-28 2013-06-05 Contipro Biotech S.R.O. Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
US9294226B2 (en) 2012-03-26 2016-03-22 Qualcomm Incorporated Universal object delivery and template-based file delivery
FR2997014B1 (fr) 2012-10-24 2015-03-20 Teoxane Composition sterile dermo-injectable
FR3005056B1 (fr) * 2013-04-24 2016-04-01 Ayawane Hydrogel a base de polysaccharides natifs et/ou fonctionnalises, phosphates co-reticules
RU2689559C2 (ru) * 2013-06-28 2019-05-28 Гальдерма С.А. Способ получения продукта из поперечно-сшитой гиалуроновой кислоты
US9421198B2 (en) 2013-07-30 2016-08-23 Teoxane Composition comprising hyaluronic acid and mepivacaine
ITUD20130119A1 (it) * 2013-09-12 2015-03-13 Limacorporate Spa Idrogel biocompatibile per uso biomedico o farmaceutico, polimero intermedio per realizzare detto idrogel biocompatibile e relativo metodo di realizzazione
EP3068408A4 (en) * 2013-11-14 2017-09-06 University Medical Pharmaceuticals Corporation Microneedles for therapeutic agent delivery with improved mechanical properties
JP6081617B2 (ja) * 2014-01-31 2017-02-15 生化学工業株式会社 ジアミン架橋剤、酸性多糖架橋体、及び医用材料
PL3397651T3 (pl) 2015-12-29 2021-02-08 Galderma S.A. Węglowodanowy środek sieciujący
WO2018053111A1 (en) 2016-09-15 2018-03-22 University Of Utah Research Foundation In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
JP2019532708A (ja) * 2016-09-21 2019-11-14 ネスレ スキン ヘルス エス アー 二価の亜鉛カチオンを含むヒアルロン酸ゲル
AR111190A1 (es) 2017-03-22 2019-06-12 Genentech Inc Composiciones en hidrogel de prodrogas entrecruzadas de ácido hialurónico y métodos relacionados
WO2019001784A1 (en) 2017-06-28 2019-01-03 Nestlé Skin Health Sa HYALURONIC ACID GEL WITH A DIVALENT CATION
CN107469090B (zh) * 2017-08-15 2020-05-12 浙江大学 可共载抗肿瘤药物和核酸药物的纳米载体及抗肿瘤药物纳米制剂
CN111228653A (zh) 2018-11-13 2020-06-05 格莱科米拉治疗公司 用电离辐射加强癌症治疗的方法
EP3659632A1 (en) 2018-11-29 2020-06-03 Nestlé Skin Health SA Post-crosslinking partial degradation of amide crosslinked hydrogels
KR20220005465A (ko) * 2019-04-19 2022-01-13 조인테라퓨틱스 에스알엘 작용화된 히알루론산의 가교결합 중합체 및 염증 상태의 치료에서의 이의 용도
CN110123741B (zh) * 2019-06-24 2022-02-08 中国医学科学院基础医学研究所 一种铁交联透明质酸纳米凝胶、其制备方法以及用途
CN110684211B (zh) * 2019-10-14 2022-07-12 宁夏妙朗生物科技有限公司 制备抵抗α-葡萄糖苷酶水解的交联右旋糖苷凝胶的方法
KR20220110786A (ko) 2019-12-02 2022-08-09 갈더마 홀딩 소시에떼 아노님 고분자량 에스테틱 조성물
WO2022109050A1 (en) * 2020-11-18 2022-05-27 Bexson Biomedical, Inc. Complexing agent salt formulations of pharmaceutical compounds
JP2023551145A (ja) 2020-11-18 2023-12-07 ベクソン バイオメディカル，インク． 医薬化合物の錯化剤塩製剤
WO2023148619A1 (en) 2022-02-01 2023-08-10 Galderma Holding SA Methods of producing crosslinked hyaluronic acid hydrogels
CN114561046B (zh) * 2022-02-28 2023-10-27 江南大学 一种胍基透明质酸型抗菌水凝胶及其制备方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4716224A (en) * 1984-05-04 1987-12-29 Seikagaku Kogyo Co. Ltd. Crosslinked hyaluronic acid and its use
SE442820B (sv) * 1984-06-08 1986-02-03 Pharmacia Ab Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut
SE8501022L (sv) * 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
IT1198449B (it) * 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
AU660147B2 (en) * 1990-05-04 1995-06-15 Perio Products Ltd. Colonic drug delivery system
RU2017751C1 (ru) * 1991-05-22 1994-08-15 Институт пищевых веществ РАН Способ получения гиалуроновой кислоты
ATE193654T1 (de) * 1991-08-16 2000-06-15 Miles A Galin Mit arzneimittel überzogenes lichtbrechendes implantat für die vordere augenkammer
IT1254170B (it) * 1991-12-18 1995-09-11 Mini Ricerca Scient Tecnolog Membrane composite per la rigenerazione guidata di tessuti
CA2076732C (en) * 1992-04-17 2006-05-09 Kimberly-Clark Worldwide, Inc. Modified polysaccharides having improved absorbent properties and process for the preparation thereof
JPH06154596A (ja) * 1992-11-18 1994-06-03 Sanyo Chem Ind Ltd 耐塩安定性吸収剤及びその製法
US5616568A (en) * 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
JPH0959303A (ja) * 1995-08-22 1997-03-04 Shiseido Co Ltd 生体適合性ヒアルロン酸ゲル及びその用途
FR2752843B1 (fr) * 1996-08-30 1998-10-16 Sod Conseils Rech Applic Copolymeres reticules a base de polymeres polycarboxyliques et leur utilisation comme support de composition pharmaceutique
IT1303738B1 (it) * 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.

Also Published As

Publication number Publication date
PT1144459E (pt) 2003-01-31
RU2230752C2 (ru) 2004-06-20
ES2184521T3 (es) 2003-04-01
CZ296842B6 (cs) 2006-06-14
WO2000027887A2 (en) 2000-05-18
US6831172B1 (en) 2004-12-14
CN1328573A (zh) 2001-12-26
EP1144459B2 (en) 2011-02-23
ATE225371T1 (de) 2002-10-15
TR200101324T2 (tr) 2001-09-21
ES2184521T5 (es) 2011-06-13
HK1041011B (zh) 2004-10-08
CN1131241C (zh) 2003-12-17
KR20010101001A (ko) 2001-11-14
DE69903351T3 (de) 2012-02-09
KR100674177B1 (ko) 2007-01-24
EP1144459A2 (en) 2001-10-17
HU229668B1 (en) 2014-04-28
ZA200103799B (en) 2002-08-12
HUP0104296A2 (hu) 2002-03-28
DE69903351D1 (de) 2002-11-07
NO20012315D0 (no) 2001-05-10
DK1144459T3 (da) 2003-02-03
AU2660000A (en) 2000-05-29
NZ511306A (en) 2003-05-30
JP2002529550A (ja) 2002-09-10
IT1303735B1 (it) 2001-02-23
NO20012315L (no) 2001-07-06
HK1041011A1 (en) 2002-06-28
CA2350667A1 (en) 2000-05-18
EP1144459B1 (en) 2002-10-02
DK1144459T4 (da) 2011-06-06
CZ20011650A3 (cs) 2001-09-12
BR9915235A (pt) 2001-07-24
AU757102B2 (en) 2003-01-30
WO2000027887A3 (en) 2000-11-16
HUP0104296A3 (en) 2003-12-29
DE69903351T2 (de) 2003-07-03
ITMI982440A1 (it) 2000-05-11

Similar Documents

Publication Publication Date Title
IL143063A0 (en) Cross-linked hyaluronic acids and medical uses thereof
CA2359318A1 (en) Biomaterials formed by nucleophilic addition reaction to conjugated unsaturated groups
AU3035189A (en) Ultrasonic contrast agents, process for producing them and their use as diagnostic and therapeutic agents
GB9902652D0 (en) Process
AU7954394A (en) Seeded microemulsioin polymerization for the production of small polymer particles
DK0991653T3 (da) Nye forbindelser
BR9508031A (pt) Composto antiviral composição farmacéutica ou veterinária e processo para o tratamento antiviral profilático ou terapéuitco de um humano ou animal náo humano e uso do composto
IL115790A0 (en) Pharmaceutical compositions containing boronic ester and acid compounds and methods for the preparation thereof
AU2003273466A1 (en) Polyamino acids functionalized by at least one hydrophobic group and the therapeutic applications thereof
WO2001044489A3 (de) Galactomannan-oligosaccharide und verfahren zu deren herstellung sowie deren verwendung
AU4871797A (en) Magnesium (-)hydroxycitrate, preparation process, uses and compositions, in particular pharmaceutical compositions, containing it
ES2185911T3 (es) Composiciones farmaceuticas que contienen polimeros de ortoester tamponados.
CA2372986A1 (en) Process for the condensation of polyamides
MX9705726A (es) Amidas del acido alcoximinoacetico.
EP0976766A4 (en) POLYMERS, PROCESSES FOR PRODUCING THE SAME, AND CURABLE COMPOSITIONS PRODUCED FROM SUCH POLYMERS
AU2003279567A1 (en) Sterilizing polymers and preparation and use thereof
IL184227A0 (en) Biologically active peptides
MY128260A (en) Cyclopentane-and-pentene-b-amino acids
IL93197A0 (en) Derivatives of 3-pyroglutamyl-thia-zolidine-4-carboxylic acid
EP0648784A3 (de) Verfahren zur Herstellung von Telechelen.
BR9710992A (pt) Derivados anticovulsivos úteis no tratamento de psorìase
AU2910800A (en) Novel substituted 3-phenoxy and 3-phenylalkyloxy-2-phenyl-propylamines
MY130723A (en) Accelerator for the production of polyamides from aminonitriles
AU7417794A (en) Process for the reduction of sulfoxide groups in polymers
ZA953683B (en) Process for the manufacture of pharmaceutical grade ranitidine base

Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees