ES2185911T3 - Composiciones farmaceuticas que contienen polimeros de ortoester tamponados. - Google Patents

Composiciones farmaceuticas que contienen polimeros de ortoester tamponados.

Info

Publication number
ES2185911T3
ES2185911T3 ES97906128T ES97906128T ES2185911T3 ES 2185911 T3 ES2185911 T3 ES 2185911T3 ES 97906128 T ES97906128 T ES 97906128T ES 97906128 T ES97906128 T ES 97906128T ES 2185911 T3 ES2185911 T3 ES 2185911T3
Authority
ES
Spain
Prior art keywords
ortoester
polymers
pharmaceutical compositions
compositions containing
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97906128T
Other languages
English (en)
Inventor
Robert Gurny
Monia Zignani
Cyrus Tabatabay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2185911T3 publication Critical patent/ES2185911T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats

Abstract

LA PRESENTE INVENCION SE REFIERE A UNA COMPOSICION FARMACEUTICA PARA LA LIBERACION CONTROLADA DE AGENTES TERAPEUTICOS A PARTIR DE ORTO ESTER POLIMEROS DEL ACIDO CARBOXILICO. LA COMPOSICION CONTIENE UNA SAL FARMACEUTICAMENTE ACEPTABLE DE UN ACIDO, EL CUAL JUNTO CON EL ACIDO R 1 -COOH SE LIBERA DE LA CO MPOSICION DEL ORTO ESTER POLIMERO (I) Y FORMA UN SISTEMA TAMPON EN UN INTERVALO DE PH FISIOLOGICAMENTE ACEPTABLE.
ES97906128T 1996-03-05 1997-02-26 Composiciones farmaceuticas que contienen polimeros de ortoester tamponados. Expired - Lifetime ES2185911T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96103391 1996-03-05

Publications (1)

Publication Number Publication Date
ES2185911T3 true ES2185911T3 (es) 2003-05-01

Family

ID=8222532

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97906128T Expired - Lifetime ES2185911T3 (es) 1996-03-05 1997-02-26 Composiciones farmaceuticas que contienen polimeros de ortoester tamponados.

Country Status (11)

Country Link
US (1) US6440460B1 (es)
EP (1) EP0885014B1 (es)
JP (1) JP4225570B2 (es)
KR (1) KR100441821B1 (es)
AT (1) ATE226450T1 (es)
AU (1) AU722303C (es)
DE (1) DE69716586T2 (es)
DK (1) DK0885014T3 (es)
ES (1) ES2185911T3 (es)
PT (1) PT885014E (es)
WO (1) WO1997032606A1 (es)

Families Citing this family (20)

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Publication number Priority date Publication date Assignee Title
US20020099438A1 (en) * 1998-04-15 2002-07-25 Furst Joseph G. Irradiated stent coating
US20030040790A1 (en) 1998-04-15 2003-02-27 Furst Joseph G. Stent coating
US8070796B2 (en) 1998-07-27 2011-12-06 Icon Interventional Systems, Inc. Thrombosis inhibiting graft
US7967855B2 (en) 1998-07-27 2011-06-28 Icon Interventional Systems, Inc. Coated medical device
US7168489B2 (en) * 2001-06-11 2007-01-30 Halliburton Energy Services, Inc. Orthoester compositions and methods for reducing the viscosified treatment fluids
US8016881B2 (en) 2002-07-31 2011-09-13 Icon Interventional Systems, Inc. Sutures and surgical staples for anastamoses, wound closures, and surgical closures
ATE412684T1 (de) * 2002-09-09 2008-11-15 Nektar Therapeutics Al Corp Verfahren zur herstellung von wasserlöslichen polymerderivaten mit terminalen carboxylgruppen
US7691381B2 (en) * 2004-04-15 2010-04-06 Allergan, Inc. Stabilized biodegradable neurotoxin implants
US20060200048A1 (en) * 2005-03-03 2006-09-07 Icon Medical Corp. Removable sheath for device protection
US9107899B2 (en) 2005-03-03 2015-08-18 Icon Medical Corporation Metal alloys for medical devices
US7540995B2 (en) 2005-03-03 2009-06-02 Icon Medical Corp. Process for forming an improved metal alloy stent
WO2006110197A2 (en) 2005-03-03 2006-10-19 Icon Medical Corp. Polymer biodegradable medical device
US20080114076A1 (en) * 2006-11-09 2008-05-15 Alcon Manufacturing Ltd. Punctal plug comprising a water-insoluble polymeric matrix
AR063621A1 (es) * 2006-11-09 2009-02-04 Alcon Res Ltd Matriz polimerica insoluble en agua para la administracion de farmacos
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
US8398916B2 (en) 2010-03-04 2013-03-19 Icon Medical Corp. Method for forming a tubular medical device
CN106535826A (zh) 2014-06-24 2017-03-22 怡康医疗股份有限公司 用于医疗装置的改进的金属合金
US11766506B2 (en) 2016-03-04 2023-09-26 Mirus Llc Stent device for spinal fusion
JP6633777B2 (ja) 2017-08-24 2020-01-22 ノヴォ ノルディスク アー／エス Ｇｌｐ−１組成物及びその使用
US11318191B2 (en) 2020-02-18 2022-05-03 Novo Nordisk A/S GLP-1 compositions and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093709A (en) * 1975-01-28 1978-06-06 Alza Corporation Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates)
US4010196A (en) * 1975-06-25 1977-03-01 American Home Products Corporation Linear polyester salts
US4268643A (en) * 1979-10-25 1981-05-19 Societa Italiana Resine S.I.R. S.P.A. Process for improving the stability of acetal polymers
US4346709A (en) * 1980-11-10 1982-08-31 Alza Corporation Drug delivery devices comprising erodible polymer and erosion rate modifier
DE3168032D1 (en) * 1980-11-10 1985-02-14 Alza Corp Erodible polymer containing erosion rate modifier
DE3642662A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Parenterale depotzubereitungen von regulatorischen peptiden enthaltend calciumacetat-glycerin-addukt, verfahren zu ihrer herstellung sowie die verwendung des addukts
US5030457A (en) 1989-08-28 1991-07-09 Pharmaceutical Delivery Systems, Inc. Bioerodible polymers useful for the controlled release of therapeutic agents
JPH05502465A (ja) 1989-08-28 1993-04-28 ファーマスーティカル　デリバリー　システムズ 治療薬剤の制御放出のために有用な生体内で分解し得るポリマー
AU2261592A (en) 1991-06-20 1993-01-25 Pharmaceutical Delivery Systems, Inc. Pulsed release of high molecular weight therapeutic agents from bioerodible polymer compositions
US5700485A (en) * 1992-09-10 1997-12-23 Children's Medical Center Corporation Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
US5869079A (en) * 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents

Also Published As

Publication number Publication date
EP0885014B1 (en) 2002-10-23
DK0885014T3 (da) 2003-02-24
US6440460B1 (en) 2002-08-27
WO1997032606A1 (en) 1997-09-12
AU722303B2 (en) 2000-07-27
KR19990087477A (ko) 1999-12-27
ATE226450T1 (de) 2002-11-15
EP0885014A1 (en) 1998-12-23
PT885014E (pt) 2003-02-28
JP4225570B2 (ja) 2009-02-18
KR100441821B1 (ko) 2004-10-15
AU722303C (en) 2001-12-06
DE69716586D1 (de) 2002-11-28
DE69716586T2 (de) 2003-07-17
AU2093497A (en) 1997-09-22
JP2000506148A (ja) 2000-05-23

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