PL1817347T3 - Sposób sieciowania kwasu hialuronowego za pomocą diwinylosulfonu - Google Patents
Sposób sieciowania kwasu hialuronowego za pomocą diwinylosulfonuInfo
- Publication number
- PL1817347T3 PL1817347T3 PL05804061T PL05804061T PL1817347T3 PL 1817347 T3 PL1817347 T3 PL 1817347T3 PL 05804061 T PL05804061 T PL 05804061T PL 05804061 T PL05804061 T PL 05804061T PL 1817347 T3 PL1817347 T3 PL 1817347T3
- Authority
- PL
- Poland
- Prior art keywords
- divinylsulfone
- cross
- hyaluronic acid
- linking hyaluronic
- linking
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
- 238000004132 cross linking Methods 0.000 title 1
- AFOSIXZFDONLBT-UHFFFAOYSA-N divinyl sulfone Chemical compound C=CS(=O)(=O)C=C AFOSIXZFDONLBT-UHFFFAOYSA-N 0.000 title 1
- 229920002674 hyaluronan Polymers 0.000 title 1
- 229960003160 hyaluronic acid Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/738—Cross-linked polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Materials Engineering (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Materials For Medical Uses (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200401824 | 2004-11-24 | ||
| EP05804061.9A EP1817347B1 (en) | 2004-11-24 | 2005-11-24 | Method of cross-linking hyaluronic acid with divinylsulfone |
| PCT/DK2005/000753 WO2006056204A1 (en) | 2004-11-24 | 2005-11-24 | Method of cross-linking hyaluronic acid with divinylsulfone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1817347T3 true PL1817347T3 (pl) | 2017-10-31 |
Family
ID=36051535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05804061T PL1817347T3 (pl) | 2004-11-24 | 2005-11-24 | Sposób sieciowania kwasu hialuronowego za pomocą diwinylosulfonu |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US8481080B2 (pl) |
| EP (1) | EP1817347B1 (pl) |
| CN (1) | CN101107270B (pl) |
| DK (1) | DK1817347T3 (pl) |
| ES (1) | ES2636998T3 (pl) |
| PL (1) | PL1817347T3 (pl) |
| PT (1) | PT1817347T (pl) |
| WO (1) | WO2006056204A1 (pl) |
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| JP2008255061A (ja) * | 2007-04-06 | 2008-10-23 | Shiseido Co Ltd | 可溶性架橋ヒアルロン酸含有眼用組成物 |
| AU2008256819A1 (en) | 2007-05-23 | 2008-12-04 | Allergan, Inc. | Cross-linked collagen and uses thereof |
| US20110077737A1 (en) * | 2007-07-30 | 2011-03-31 | Allergan, Inc. | Tunably Crosslinked Polysaccharide Compositions |
| EP2199308B1 (en) * | 2007-09-28 | 2012-02-08 | Shiseido Company, Ltd. | Swellable crosslinked hyaluronic acid powder and method for producing the same |
| US8697044B2 (en) | 2007-10-09 | 2014-04-15 | Allergan, Inc. | Crossed-linked hyaluronic acid and collagen and uses thereof |
| BRPI0819075A2 (pt) | 2007-11-16 | 2014-10-07 | Vicept Therapeutics Inc | Método para tratar púrpura em um indivíduo e método para diminuir a púrpura em um indivíduo antes de um procedimento cirúrgico |
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| CZ302504B6 (cs) | 2009-12-11 | 2011-06-22 | Contipro C A.S. | Derivát kyseliny hyaluronové oxidovaný v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd, zpusob jeho prípravy a zpusob jeho modifikace |
| US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
| US9114188B2 (en) | 2010-01-13 | 2015-08-25 | Allergan, Industrie, S.A.S. | Stable hydrogel compositions including additives |
| KR101764451B1 (ko) | 2010-03-12 | 2017-08-02 | 알러간 인더스트리 에스에이에스 | 피부 상태 개선을 위한 히알루론안 폴리머 및 만니톨을 포함하는 유체 조성물 |
| CA2794254C (en) | 2010-03-22 | 2018-09-04 | Allergan, Inc. | Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation |
| JP5591995B2 (ja) * | 2010-03-30 | 2014-09-17 | イストセル,エセ.エレ. | ウォートンジェリー臍帯由来の新規の生体材料 |
| US9005605B2 (en) | 2010-08-19 | 2015-04-14 | Allergan, Inc. | Compositions and soft tissue replacement methods |
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| RS62488B1 (sr) | 2011-08-10 | 2021-11-30 | Glycores 2000 Srl | Unakrsno povezani hijaluronat male molekulske težine, otporan na razgradnju |
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| CZ304654B6 (cs) * | 2012-11-27 | 2014-08-20 | Contipro Biotech S.R.O. | Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití |
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| LT3049055T (lt) * | 2013-09-27 | 2018-07-25 | Anteis S.A. | Injekcinio hidrogelio, sterilizuoto karščiu, sudaryto iš hialurono rūgšties, turinčio miltelių pavidalo lidokaino ir šarminio agento, gamybos būdas |
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| WO2020057606A1 (en) * | 2018-09-20 | 2020-03-26 | The Hong Kong University Of Science And Technology | Eyedrop compositions |
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| KR102015857B1 (ko) * | 2019-04-08 | 2019-08-30 | (주)우성씨앤티 | 가교 히알루론산과 프리바이오틱스를 활성 성분으로 포함하는 화장품 조성물 |
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| US4716224A (en) | 1984-05-04 | 1987-12-29 | Seikagaku Kogyo Co. Ltd. | Crosslinked hyaluronic acid and its use |
| SE442820B (sv) * | 1984-06-08 | 1986-02-03 | Pharmacia Ab | Gel av tverbunden hyaluronsyra for anvendning som glaskroppssubstitut |
| US4582865A (en) | 1984-12-06 | 1986-04-15 | Biomatrix, Inc. | Cross-linked gels of hyaluronic acid and products containing such gels |
| US4713448A (en) * | 1985-03-12 | 1987-12-15 | Biomatrix, Inc. | Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues |
| EP0224987B1 (en) * | 1985-11-29 | 1992-04-15 | Biomatrix, Inc. | Drug delivery systems based on hyaluronan, derivatives thereof and their salts and method of producing same |
| JPS6345198A (ja) | 1986-04-23 | 1988-02-26 | Sumitomo Electric Ind Ltd | 多元系結晶の製造方法 |
| IT1198449B (it) | 1986-10-13 | 1988-12-21 | F I D I Farmaceutici Italiani | Esteri di alcoli polivalenti di acido ialuronico |
| US5017229A (en) | 1990-06-25 | 1991-05-21 | Genzyme Corporation | Water insoluble derivatives of hyaluronic acid |
| US5356883A (en) | 1989-08-01 | 1994-10-18 | Research Foundation Of State University Of N.Y. | Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use |
| US5767079A (en) * | 1992-07-08 | 1998-06-16 | Celtrix Pharmaceuticals, Inc. | Method of treating ophthalmic disorders using TGF -β |
| US5866120A (en) * | 1995-11-22 | 1999-02-02 | Advanced Corneal Systems, Inc. | Method for accelerating clearance of hemorrhagic blood from the vitreous humor with hyaluronidase |
| IT1303735B1 (it) * | 1998-11-11 | 2001-02-23 | Falorni Italia Farmaceutici S | Acidi ialuronici reticolati e loro usi medici. |
| FR2827290B1 (fr) * | 2001-07-13 | 2004-07-09 | Pierre Jouan Biotechnologies Sa | Procede d'obtention d'une fraction proteique enrichie en tgf-beta sous forme activee, fraction proteique et applications therapeutiques |
| RU2346049C2 (ru) * | 2001-12-21 | 2009-02-10 | Новозимс Биополимер А/С | Способ получения гиалуронана в рекомбинантной клетке-хозяине |
| WO2003089476A1 (en) | 2002-04-17 | 2003-10-30 | Genzyme Corporation | Cross-linked hyaluronate compounds |
| WO2004067575A1 (en) | 2003-01-31 | 2004-08-12 | Biosphere S.P.A. | Water soluble and biocompatible gels of hyaluronic acid cross-linked with bi-functional l-aminoacids or l-aminoesters |
| AU2004312532B2 (en) | 2003-12-30 | 2010-05-20 | Genzyme Corporation | Cohesive gels form cross-linked hyaluronan and/or hylan, their preparation and use |
| WO2005112888A2 (en) | 2004-05-20 | 2005-12-01 | Mentor Corporation | Methods for making injectable polymer hydrogels |
-
2005
- 2005-11-24 PL PL05804061T patent/PL1817347T3/pl unknown
- 2005-11-24 ES ES05804061.9T patent/ES2636998T3/es not_active Expired - Lifetime
- 2005-11-24 EP EP05804061.9A patent/EP1817347B1/en not_active Expired - Lifetime
- 2005-11-24 WO PCT/DK2005/000753 patent/WO2006056204A1/en not_active Ceased
- 2005-11-24 DK DK05804061.9T patent/DK1817347T3/en active
- 2005-11-24 PT PT58040619T patent/PT1817347T/pt unknown
- 2005-11-24 US US11/719,790 patent/US8481080B2/en active Active
- 2005-11-24 CN CN2005800471013A patent/CN101107270B/zh not_active Expired - Lifetime
-
2013
- 2013-06-07 US US13/912,894 patent/US20130338100A1/en not_active Abandoned
-
2015
- 2015-01-07 US US14/591,522 patent/US20150190420A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20090155362A1 (en) | 2009-06-18 |
| EP1817347A1 (en) | 2007-08-15 |
| US8481080B2 (en) | 2013-07-09 |
| CN101107270A (zh) | 2008-01-16 |
| US20130338100A1 (en) | 2013-12-19 |
| PT1817347T (pt) | 2017-07-21 |
| US20150190420A1 (en) | 2015-07-09 |
| WO2006056204A1 (en) | 2006-06-01 |
| DK1817347T3 (en) | 2017-08-14 |
| CN101107270B (zh) | 2011-11-23 |
| ES2636998T3 (es) | 2017-10-10 |
| EP1817347B1 (en) | 2017-05-17 |
| WO2006056204A8 (en) | 2006-08-24 |
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