IL139090A0 - Compounds with growth hormone releasing properties - Google Patents
Compounds with growth hormone releasing propertiesInfo
- Publication number
- IL139090A0 IL139090A0 IL13909099A IL13909099A IL139090A0 IL 139090 A0 IL139090 A0 IL 139090A0 IL 13909099 A IL13909099 A IL 13909099A IL 13909099 A IL13909099 A IL 13909099A IL 139090 A0 IL139090 A0 IL 139090A0
- Authority
- IL
- Israel
- Prior art keywords
- compounds
- growth hormone
- hormone releasing
- releasing properties
- disubstituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK63698 | 1998-05-11 | ||
DKPA199800875 | 1998-07-01 | ||
PCT/DK1999/000260 WO1999058501A1 (en) | 1998-05-11 | 1999-05-10 | Compounds with growth hormone releasing properties |
Publications (1)
Publication Number | Publication Date |
---|---|
IL139090A0 true IL139090A0 (en) | 2001-11-25 |
Family
ID=26064372
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13909099A IL139090A0 (en) | 1998-05-11 | 1999-05-10 | Compounds with growth hormone releasing properties |
IL139090A IL139090A (en) | 1998-05-11 | 2000-10-17 | Compounds with growth hormone release properties |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL139090A IL139090A (en) | 1998-05-11 | 2000-10-17 | Compounds with growth hormone release properties |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP1077941B1 (el) |
JP (2) | JP4142253B2 (el) |
KR (1) | KR100593601B1 (el) |
CN (1) | CN1142911C (el) |
AT (1) | ATE439346T1 (el) |
AU (1) | AU757217B2 (el) |
BR (1) | BR9910329A (el) |
CA (1) | CA2329881C (el) |
CY (1) | CY1109626T1 (el) |
CZ (1) | CZ301276B6 (el) |
DE (1) | DE69941255D1 (el) |
DK (1) | DK1077941T3 (el) |
ES (1) | ES2331102T3 (el) |
HU (1) | HUP0102071A3 (el) |
IL (2) | IL139090A0 (el) |
NO (1) | NO318080B1 (el) |
PL (1) | PL194560B1 (el) |
PT (1) | PT1077941E (el) |
RU (1) | RU2243215C2 (el) |
SI (1) | SI1077941T1 (el) |
TW (1) | TWI222969B (el) |
UA (1) | UA72210C2 (el) |
WO (1) | WO1999058501A1 (el) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2244474T3 (es) | 1999-09-29 | 2005-12-16 | Ortho-Mcneil Pharmaceutical, Inc. | Isonipecotamida para el tratamiento de trastornos mediados por integrina. |
UA73530C2 (uk) * | 1999-11-10 | 2005-08-15 | Ново Нордіск А/С | Сполука з властивостями вивільнювати гормон росту |
US20010020012A1 (en) * | 2000-02-01 | 2001-09-06 | Andersen Maibritt Bansholm | Use of compounds for the regulation of food intake |
WO2002046156A2 (en) | 2000-12-06 | 2002-06-13 | Sepracor, Inc. | 4,4-disubstituted piperidines for use as dopamine, serotonin and norepinephrine ligands |
HUP0303484A2 (hu) * | 2001-03-02 | 2004-01-28 | Bristol-Myers Squibb Company | Melanokortin receptor modulátoraiként hasznos vegyületek és a vegyületeket tartalmazó gyógyszerkészítmények |
DE10113604A1 (de) * | 2001-03-20 | 2002-10-24 | Ibfb Gmbh Privates Inst Fuer B | Verfahren zur Spaltung des humanen Wachstumshormons GH |
US7081460B2 (en) | 2001-04-09 | 2006-07-25 | Ortho-Mcneil Pharmaceutical, Inc. | Quinazoline and quinazoline-like compounds for the treatment of integrin-mediated disorders |
US6911447B2 (en) | 2001-04-25 | 2005-06-28 | The Procter & Gamble Company | Melanocortin receptor ligands |
CA2462200A1 (en) | 2001-08-10 | 2003-02-20 | Palatin Technologies, Inc. | Peptidomimetics of biologically active metallopeptides |
US7026335B2 (en) | 2002-04-30 | 2006-04-11 | The Procter & Gamble Co. | Melanocortin receptor ligands |
EP1407779A1 (en) | 2002-10-10 | 2004-04-14 | Gastrotech A/S | Use of ghrelin for treating low body weight and body fat in gastrectomized individuals |
US7132539B2 (en) | 2002-10-23 | 2006-11-07 | The Procter & Gamble Company | Melanocortin receptor ligands |
US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
EP1735055A1 (en) * | 2004-03-30 | 2006-12-27 | Sapphire Therapeutics, Inc. | Method of reducing c-reactive protein using growth hormone secretagogues |
EP2298760B1 (en) * | 2004-06-29 | 2015-08-05 | Helsinn Healthcare S.A. | Crystal forms of (3R)-1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide |
ES2388501T3 (es) * | 2004-08-12 | 2012-10-16 | Helsinn Healthcare S.A. | Uso de secretagogos de la hormona de crecimiento para estimular la motilidad del sistema gastrointestinal |
CU23558A1 (es) | 2006-02-28 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento |
CN101595107A (zh) * | 2006-06-30 | 2009-12-02 | 先灵公司 | 能提高p53活性的有取代哌啶及其用途 |
JP2010518090A (ja) | 2007-02-09 | 2010-05-27 | トランザイム・ファーマ,インコーポレイテッド | 大環状グレリン受容体修飾因子およびその使用方法 |
WO2012131090A1 (en) | 2011-03-31 | 2012-10-04 | Galderma Research & Development | Method for treatment of xeroderma pigmentosum |
CN114805305B (zh) * | 2022-04-20 | 2024-04-26 | 成都诺和晟泰生物科技有限公司 | 一种化合物及其应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1174504A (zh) * | 1993-11-09 | 1998-02-25 | 麦克公司 | 促进生长激素释放的哌啶、吡咯烷和六氢-1h-吖庚因 |
US5492916A (en) * | 1993-12-23 | 1996-02-20 | Merck & Co., Inc. | Di- and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone |
US5721250A (en) * | 1993-12-23 | 1998-02-24 | Merck & Co. Inc. | Di-and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone |
US5559128A (en) * | 1995-04-18 | 1996-09-24 | Merck & Co., Inc. | 3-substituted piperidines promote release of growth hormone |
WO1996035713A1 (en) * | 1995-05-08 | 1996-11-14 | Pfizer, Inc. | Dipeptides which promote release of growth hormone |
EP0828754B1 (en) * | 1995-05-29 | 2005-02-02 | Pfizer Inc. | Dipeptides which promote release of growth hormone |
GB2308064A (en) * | 1995-10-31 | 1997-06-18 | Merck & Co Inc | Treatment of congestive heart failure with a growth hormone secretagogue |
AU2722297A (en) * | 1996-04-03 | 1997-10-22 | Merck & Co., Inc. | Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone |
DE69734215T2 (de) * | 1996-07-22 | 2006-06-29 | Novo Nordisk A/S | Verbindungen mit Wachstumshormon-freisetzenden Eigenschaften |
WO1998010653A1 (en) * | 1996-09-13 | 1998-03-19 | Merck & Co., Inc. | Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone |
WO1998016527A1 (en) * | 1996-10-15 | 1998-04-23 | Fujisawa Pharmaceutical Co., Ltd. | Benzoxepine derivatives which promote release of growth hormone |
-
1999
- 1999-05-10 PT PT99919125T patent/PT1077941E/pt unknown
- 1999-05-10 CN CNB998060100A patent/CN1142911C/zh not_active Expired - Lifetime
- 1999-05-10 BR BR9910329-0A patent/BR9910329A/pt not_active Application Discontinuation
- 1999-05-10 HU HU0102071A patent/HUP0102071A3/hu unknown
- 1999-05-10 DK DK99919125T patent/DK1077941T3/da active
- 1999-05-10 RU RU2000131184/04A patent/RU2243215C2/ru active
- 1999-05-10 KR KR1020007012458A patent/KR100593601B1/ko not_active IP Right Cessation
- 1999-05-10 WO PCT/DK1999/000260 patent/WO1999058501A1/en active IP Right Grant
- 1999-05-10 IL IL13909099A patent/IL139090A0/xx active IP Right Grant
- 1999-05-10 AT AT99919125T patent/ATE439346T1/de active
- 1999-05-10 SI SI9931036T patent/SI1077941T1/sl unknown
- 1999-05-10 AU AU37010/99A patent/AU757217B2/en not_active Expired
- 1999-05-10 PL PL344042A patent/PL194560B1/pl unknown
- 1999-05-10 CZ CZ20004129A patent/CZ301276B6/cs not_active IP Right Cessation
- 1999-05-10 ES ES99919125T patent/ES2331102T3/es not_active Expired - Lifetime
- 1999-05-10 CA CA2329881A patent/CA2329881C/en not_active Expired - Lifetime
- 1999-05-10 DE DE69941255T patent/DE69941255D1/de not_active Expired - Lifetime
- 1999-05-10 EP EP99919125A patent/EP1077941B1/en not_active Expired - Lifetime
- 1999-05-10 JP JP2000548305A patent/JP4142253B2/ja not_active Expired - Lifetime
- 1999-05-24 TW TW088108436A patent/TWI222969B/zh not_active IP Right Cessation
- 1999-10-05 UA UA2000116293A patent/UA72210C2/uk unknown
-
2000
- 2000-10-17 IL IL139090A patent/IL139090A/en not_active IP Right Cessation
- 2000-11-10 NO NO20005668A patent/NO318080B1/no not_active IP Right Cessation
-
2008
- 2008-03-12 JP JP2008062381A patent/JP4938708B2/ja not_active Expired - Lifetime
-
2009
- 2009-11-12 CY CY20091101195T patent/CY1109626T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed |