IL136145A0 - Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof - Google Patents

Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof

Info

Publication number
IL136145A0
IL136145A0 IL13614598A IL13614598A IL136145A0 IL 136145 A0 IL136145 A0 IL 136145A0 IL 13614598 A IL13614598 A IL 13614598A IL 13614598 A IL13614598 A IL 13614598A IL 136145 A0 IL136145 A0 IL 136145A0
Authority
IL
Israel
Prior art keywords
inhibition
processes
preparation
pharmaceutical compositions
heterocyclic compounds
Prior art date
Application number
IL13614598A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IL136145A0 publication Critical patent/IL136145A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13614598A 1997-11-28 1998-11-18 Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof IL136145A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704404A SE9704404D0 (sv) 1997-11-28 1997-11-28 New compounds
PCT/SE1998/002091 WO1999028322A1 (en) 1997-11-28 1998-11-18 Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
IL136145A0 true IL136145A0 (en) 2001-05-20

Family

ID=20409181

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13614598A IL136145A0 (en) 1997-11-28 1998-11-18 Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof

Country Status (33)

Country Link
US (1) US6518270B1 (pt)
EP (1) EP1042324B1 (pt)
JP (1) JP2001525322A (pt)
KR (1) KR20010032559A (pt)
CN (1) CN1142933C (pt)
AR (1) AR016972A1 (pt)
AT (1) ATE233263T1 (pt)
AU (1) AU752187C (pt)
BR (1) BR9814755A (pt)
CA (1) CA2311798A1 (pt)
CZ (1) CZ292349B6 (pt)
DE (1) DE69811735T2 (pt)
DK (1) DK1042324T3 (pt)
EE (1) EE04060B1 (pt)
ES (1) ES2191356T3 (pt)
HK (1) HK1030216A1 (pt)
HU (1) HUP0100601A3 (pt)
ID (1) ID24730A (pt)
IL (1) IL136145A0 (pt)
IS (1) IS5486A (pt)
MY (1) MY121032A (pt)
NO (1) NO315704B1 (pt)
NZ (1) NZ504355A (pt)
PL (1) PL340920A1 (pt)
PT (1) PT1042324E (pt)
RU (1) RU2241000C2 (pt)
SE (1) SE9704404D0 (pt)
SK (1) SK283904B6 (pt)
TR (1) TR200001530T2 (pt)
TW (1) TW515798B (pt)
UA (1) UA70932C2 (pt)
WO (1) WO1999028322A1 (pt)
ZA (1) ZA9810468B (pt)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1463097A (en) 1996-01-04 1997-08-01 Rican Limited Helicobacter pylori bacterioferritin
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds
IL148820A0 (en) 1999-10-08 2002-09-12 Smithkline Beecham Corp Fab i inhibitors
WO2003088897A2 (en) * 2001-04-06 2003-10-30 Affinium Pharmaceuticals, Inc. Fab i inhibitors
JP2003119140A (ja) * 2001-08-08 2003-04-23 Sankyo Co Ltd ピロロピリダジン化合物を含有する医薬
KR20050008691A (ko) * 2002-04-19 2005-01-21 셀룰러 지노믹스 아이엔씨 이미다조[1,2-ａ]피라진-8-일 아민, 그의 제조방법 및사용방법
AU2003270489A1 (en) 2002-09-09 2004-03-29 Cellular Genomics, Inc. 6-ARYL-IMIDAZO(1,2-a)PYRAZIN-8-YLAMINES, METHOD OF MAKING, AND METHOD OF USE THEREOF
WO2004029057A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 内臓痛の治療または予防のための医薬組成物
WO2004029058A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 血中ガストリン濃度上昇の抑制のための医薬組成物
DK1575951T3 (da) * 2002-12-06 2014-09-15 Debiopharm Int Sa Heterocykliske forbindelser, fremgangsmåder til fremstilling deraf og deres anvendelse i terapi
WO2004072081A1 (en) 2003-02-10 2004-08-26 Cellular Genomics, Inc. Certain 8-heteroaryl-6-phenyl-imidazo[1,2-a]pyrazines as modulators of kinase activity
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
EP1608377B1 (en) * 2003-03-17 2008-10-01 Affinium Pharmaceuticals, Inc. Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics
US7405295B2 (en) 2003-06-04 2008-07-29 Cgi Pharmaceuticals, Inc. Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
WO2005005429A1 (en) 2003-06-30 2005-01-20 Cellular Genomics, Inc. Certain heterocyclic substituted imidazo[1,2-a]pyrazin-8-ylamines and methods of inhibition of bruton’s tyrosine kinase by such compounds
WO2005019220A2 (en) 2003-08-11 2005-03-03 Cellular Genomics Inc. Substituted imidazo[1,2-a]pyrazines as modulators of kinase activity
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
JP5087406B2 (ja) 2004-06-04 2012-12-05 アフィニウム ファーマシューティカルズ， インク． 治療薬ならびにその製造方法および使用方法
KR20070053231A (ko) * 2004-07-28 2007-05-23 다케다 야쿠힌 고교 가부시키가이샤 피롤로[2,3-ｃ]피리딘 화합물, 그 제조 방법 및 용도
EP1776361A1 (en) * 2004-08-02 2007-04-25 Altana Pharma AG 5-substituted 1h-pyrroloý3,2-b¨pyridines
AU2005280739B2 (en) * 2004-09-03 2010-11-11 Yuhan Corporation Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof
CN101010321B (zh) * 2004-09-03 2011-10-26 株式会社柳韩洋行 吡咯并[3,2-b]吡啶衍生物及其制备方法
JP4898683B2 (ja) * 2004-09-03 2012-03-21 ユーハン・コーポレイション ピロロ［２，３−ｃ］ピリジン誘導体及びその製造方法
WO2006025714A1 (en) 2004-09-03 2006-03-09 Yuhan Corporation PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF
US7777040B2 (en) 2005-05-03 2010-08-17 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
US7709468B2 (en) 2005-09-02 2010-05-04 Abbott Laboratories Imidazo based heterocycles
JP2009518399A (ja) * 2005-12-05 2009-05-07 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉ阻害剤および抗菌剤としてのヘテロ環アクリルアミド化合物
MX2008015747A (es) * 2006-06-06 2008-12-19 Schering Corp Imidazopirazinas como inhibidores de la proteina quinasa.
WO2008009122A1 (en) 2006-07-20 2008-01-24 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as fab i inhibitors
WO2008098374A1 (en) 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
JP5496915B2 (ja) 2008-02-13 2014-05-21 シージーアイ ファーマシューティカルズ，インコーポレーテッド ６−アリール−イミダゾ［１，２−ａ］ピラジン誘導体、その製造方法、及びその使用方法
HUE030427T2 (en) 2008-12-08 2017-05-29 Gilead Connecticut Inc Imidazopyrazine Syk inhibitors
JP5696052B2 (ja) 2008-12-08 2015-04-08 ギリアード コネチカット， インコーポレイテッド イミダゾピラジンｓｙｋ阻害剤
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
NZ602362A (en) 2010-03-11 2014-11-28 Gilead Connecticut Inc Imidazopyridines syk inhibitors
DK2861608T3 (da) 2012-06-19 2019-06-24 Debiopharm Int Sa Prodrug-derivater af (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamid
TW201602108A (zh) 2013-07-30 2016-01-16 吉李德康乃狄克公司 脾酪胺酸激酶（Ｓｙｋ）抑制劑之多晶型
AP2016009007A0 (en) 2013-07-30 2016-01-31 Gilead Connecticut Inc Formulation of syk inhibitors
PT3076976T (pt) 2013-12-04 2020-12-07 Kronos Bio Inc Métodos para tratar cancros
GB201321738D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic Agents
US9290505B2 (en) 2013-12-23 2016-03-22 Gilead Sciences, Inc. Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
UY35898A (es) 2013-12-23 2015-07-31 Gilead Sciences Inc ?compuestos inhibidores de syk y composiciones que los comprenden?.
KR20170029580A (ko) 2014-07-14 2017-03-15 길리애드 사이언시즈, 인코포레이티드 암을 치료하기 위한 조합물
CN108778286A (zh) 2016-02-26 2018-11-09 德彪药业国际股份公司 用于治疗糖尿病足感染的药物
KR102399996B1 (ko) 2017-08-25 2022-05-20 길리애드 사이언시즈, 인코포레이티드 Syk 억제제의 다형체
JP2022521413A (ja) 2019-02-22 2022-04-07 クロノス バイオ インコーポレイテッド Ｓｙｋ阻害剤としての縮合ピラジンの固体形態

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507294A (en) 1982-03-08 1985-03-26 Schering Corp. Imidazo[1,2-a]pyrazines
DE3269604D1 (en) 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
WO1991017164A1 (de) 1990-04-27 1991-11-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue pyridazine
US5041442A (en) * 1990-07-31 1991-08-20 Syntex (U.S.A.) Inc. Pyrrolo(1,2-a)pyrazines as inhibitors of gastric acid secretion
AU8712191A (en) 1990-10-15 1992-05-20 Byk Gulden Lomberg Chemische Fabrik Gmbh New diazines
JPH07500329A (ja) 1991-10-25 1995-01-12 ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング ピロロ−ピリダジン
ES2185693T3 (es) 1994-01-19 2003-05-01 Sankyo Co Derivado de pirrolopiridacina.
SE9602286D0 (sv) 1996-06-10 1996-06-10 Astra Ab New compounds
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds

Also Published As

Publication number Publication date
NO315704B1 (no) 2003-10-13
JP2001525322A (ja) 2001-12-11
CN1284078A (zh) 2001-02-14
NZ504355A (en) 2001-12-21
HUP0100601A2 (hu) 2001-09-28
RU2241000C2 (ru) 2004-11-27
SE9704404D0 (sv) 1997-11-28
CZ292349B6 (cs) 2003-09-17
TW515798B (en) 2003-01-01
DE69811735T2 (de) 2003-12-18
ID24730A (id) 2000-08-03
TR200001530T2 (tr) 2000-11-21
MY121032A (en) 2005-12-30
SK6742000A3 (en) 2001-03-12
ATE233263T1 (de) 2003-03-15
PL340920A1 (en) 2001-03-12
US6518270B1 (en) 2003-02-11
EP1042324B1 (en) 2003-02-26
HUP0100601A3 (en) 2002-10-28
WO1999028322A1 (en) 1999-06-10
KR20010032559A (ko) 2001-04-25
NO20002721D0 (no) 2000-05-26
DK1042324T3 (da) 2003-05-05
SK283904B6 (sk) 2004-04-06
PT1042324E (pt) 2003-06-30
DE69811735D1 (de) 2003-04-03
CN1142933C (zh) 2004-03-24
ES2191356T3 (es) 2003-09-01
EP1042324A1 (en) 2000-10-11
CA2311798A1 (en) 1999-06-10
AU752187C (en) 2003-09-18
CZ20001947A3 (cs) 2000-11-15
EE200000315A (et) 2001-10-15
AU752187B2 (en) 2002-09-12
UA70932C2 (uk) 2004-11-15
AU1356599A (en) 1999-06-16
AR016972A1 (es) 2001-08-01
NO20002721L (no) 2000-07-28
ZA9810468B (en) 1999-05-21
IS5486A (is) 2000-05-10
HK1030216A1 (en) 2001-04-27
BR9814755A (pt) 2000-10-03
EE04060B1 (et) 2003-06-16

Similar Documents

Publication Publication Date Title
IL136145A0 (en) Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof
HK1024248A1 (en) Compounds for inhibition of gastric acid secretion
HUP0102425A3 (en) Imidazo pyridine derivatives which inhibit gastric acid secretion, process for producing them and pharmaceutical compositions containing them
HUP0203142A3 (en) Benzodiazepine derivatives, process for preparation of the compounds, pharmaceutical compositions containing them and their use
HUP0203257A3 (en) Polymorphic forms of atorvastatin calcium, process for their preparations and pharmaceutical compositions containing them
SI1156049T1 (en) Substituted heterocyclic compounds, their process of preparation and pharmaceutical compositions containing them
HUP0203841A3 (en) 5-membered heteroaromatic compounds and use thereof for preparation of pharmaceutical compositions, and pharmaceutical compositions containing them
HUP0203183A3 (en) Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use
IL145789A0 (en) Derivatives of propionic acid, their preparation and pharmaceutical compositions containing them
IL131415A (en) Anti-inflammatory compounds, processes for their preparation and pharmaceutical compositions comprising them
HUP0204226A3 (en) Quinazoline derivatives, pharmaceutical compositions containing them, their use and process for the preparation of the compounds
HUP0200881A3 (en) Renin inhibitors, process for preparation of the compounds, pharmaceutical compositions containing them and their use
HU9800291D0 (en) Use of amido-pirimidine derivatives for producing pharmaceutical compositions for inhibiting decrease of glucose-metabolismus
IL141165A0 (en) New imidazopyridine compounds for the inhibition of acid secretion, pharmaceutical compositions thereof and process for preparing the same
IL117620A0 (en) Heterocyclic compounds processes for the preparation thereof and pharmaceutical compositions containing the same
EP1411056A3 (en) Imidazo[1,2-a]pyridine compounds that inhibit gastric acid secretion, pharmaceutical compositions thereof, and processes for their preparation
HUP0003053A3 (en) Crystalline forms of 33-epichloro-33-desoxyascomycin, process for their preparation and pharmaceutical compositions containing them
HUP0103788A3 (en) Processes for the preparation of 5-hydroxy-3-oxopentanoic acid derivatives
GB2355657B (en) Inhibitors Of Gastric Acid Secretion
SI1042324T1 (en) Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof
HUP0203270A3 (en) Hydroxamic acid derivative as inhibitor of the formation of human cd23, process for its preparation and pharmaceutical compositions containing the same
HUP0001441A3 (en) Process for the preparation of pharmaceutical compositions containing 4-aza-androst-1-ene derivatives
AU1748001A (en) Pharmaceutical composition for treatment of diarrhea
HUP0203696A3 (en) Substituted bisindolylmaleimides for the inhibition of cell proliferation, process for their preparation and pharmaceutical compositions containing them
HUP0100957A3 (en) 5-substituted pyrimidine-2-yloxy carboxylic acid derivatives, the production of the same, their use and pharmaceutical compositions containing them