IL133135A0 - Triazole dihydrogen phosphate derivatives - Google Patents

Triazole dihydrogen phosphate derivatives

Info

Publication number
IL133135A0
IL133135A0 IL13313599A IL13313599A IL133135A0 IL 133135 A0 IL133135 A0 IL 133135A0 IL 13313599 A IL13313599 A IL 13313599A IL 13313599 A IL13313599 A IL 13313599A IL 133135 A0 IL133135 A0 IL 133135A0
Authority
IL
Israel
Prior art keywords
triazole
dihydrogen phosphate
phosphate derivatives
derivatives
dihydrogen
Prior art date
Application number
IL13313599A
Other languages
English (en)
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Publication of IL133135A0 publication Critical patent/IL133135A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
    • C07F9/6518—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13313599A 1996-02-02 1999-11-25 Triazole dihydrogen phosphate derivatives IL133135A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9602080.5A GB9602080D0 (en) 1996-02-02 1996-02-02 Pharmaceutical compounds
IL12486599 1999-11-25

Publications (1)

Publication Number Publication Date
IL133135A0 true IL133135A0 (en) 2001-03-19

Family

ID=10787975

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12486597A IL124865A (en) 1996-02-02 1997-01-27 Derivatives of triazole dihydrogen phosphate, their preparation and pharmaceutical preparations containing them
IL13313598A IL133135A (en) 1996-02-02 1998-06-11 Triazole dihydrogen phosphate derivatives
IL13313599A IL133135A0 (en) 1996-02-02 1999-11-25 Triazole dihydrogen phosphate derivatives

Family Applications Before (2)

Application Number Title Priority Date Filing Date
IL12486597A IL124865A (en) 1996-02-02 1997-01-27 Derivatives of triazole dihydrogen phosphate, their preparation and pharmaceutical preparations containing them
IL13313598A IL133135A (en) 1996-02-02 1998-06-11 Triazole dihydrogen phosphate derivatives

Country Status (43)

Country Link
US (4) US6790957B2 (xx)
EP (1) EP0880533B1 (xx)
JP (1) JP2959846B2 (xx)
KR (1) KR100283546B1 (xx)
CN (1) CN1085213C (xx)
AP (1) AP678A (xx)
AT (1) ATE219089T1 (xx)
AU (1) AU709781B2 (xx)
BG (1) BG63946B1 (xx)
BR (1) BR9707257A (xx)
CA (1) CA2240777C (xx)
CO (1) CO4761066A1 (xx)
CZ (1) CZ291431B6 (xx)
DE (1) DE69713284T2 (xx)
DK (1) DK0880533T3 (xx)
DZ (1) DZ2172A1 (xx)
ES (1) ES2175336T3 (xx)
GB (1) GB9602080D0 (xx)
GT (1) GT199700016A (xx)
HK (1) HK1018217A1 (xx)
HN (1) HN1997000012A (xx)
HR (1) HRP970063B1 (xx)
HU (1) HU226133B1 (xx)
ID (1) ID15858A (xx)
IL (3) IL124865A (xx)
IS (1) IS1995B (xx)
MY (1) MY116849A (xx)
NO (1) NO323771B1 (xx)
NZ (1) NZ330654A (xx)
OA (1) OA10711A (xx)
PL (1) PL187237B1 (xx)
PT (1) PT880533E (xx)
RS (1) RS49526B (xx)
RU (1) RU2176244C2 (xx)
SA (1) SA97170578B1 (xx)
SI (1) SI0880533T1 (xx)
SK (1) SK283136B6 (xx)
TN (1) TNSN97023A1 (xx)
TR (1) TR199801440T2 (xx)
TW (1) TW434247B (xx)
UA (1) UA46828C2 (xx)
WO (1) WO1997028169A1 (xx)
ZA (1) ZA97826B (xx)

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DE19751525C2 (de) 1997-11-20 2003-02-13 Bat Cigarettenfab Gmbh Verfahren und Vorrichtung zur Regelung der Ausgangsfeuchte von Tabak
US6265584B1 (en) 1998-05-22 2001-07-24 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
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US6235728B1 (en) 1999-02-19 2001-05-22 Bristol-Myers Squibb Company Water-soluble prodrugs of azole compounds
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US6362172B2 (en) * 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
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US7540402B2 (en) * 2001-06-29 2009-06-02 Kva, Inc. Method for controlling weld metal microstructure using localized controlled cooling of seam-welded joints
US7323572B2 (en) 2002-07-16 2008-01-29 Pfizer Inc Process for controlling the hydrate mix of a compound
WO2005006860A2 (en) * 2003-07-18 2005-01-27 The Board Of Governors For Higher Education State Of Rhode Island And Providence Plantations Azole derivatives and methods for making the same
KR20070085093A (ko) * 2004-03-24 2007-08-27 파스젠, 엘엘씨. Ａｍｐ-활성화 단백질 키나아제의 약리학적 저해에 의한신규한 신경 보호 방법
CN1303073C (zh) * 2005-05-31 2007-03-07 中国人民解放军第二军医大学 取代三唑酮苄胺三唑醇类抗真菌化合物及其制备方法
EP1964843B1 (en) * 2005-12-20 2013-08-28 Eisai R&D Management Co., Ltd. Process for production of water-soluble azole prodrug
ES2533007T3 (es) 2005-12-27 2015-04-06 Otsuka Pharmaceutical Co., Ltd. Compuesto de benzoacepina soluble en agua y su composición farmacéutica
CN101389333A (zh) * 2006-02-22 2009-03-18 卫材R&D管理有限公司 稳定化药物组合物
AR072858A1 (es) * 2008-04-15 2010-09-29 Schering Corp Composiciones de alta densidad que contienen posaconazol y formulaciones que lo comprenden
CN101575330B (zh) * 2008-05-05 2012-10-31 丽珠医药集团股份有限公司 伏立康唑广谱抗真菌药物化合物、其组合物及用途
WO2011064558A2 (en) 2009-11-30 2011-06-03 Cipla Limited Pharmaceutical composition
EA032840B8 (ru) 2011-06-22 2020-06-18 Вайоми Терапеутикс Лимитед Пролекарства на основе конъюгатов противогрибковых агентов и их применение
EP2561863A1 (en) 2011-08-22 2013-02-27 Farmaprojects, S.A.U. Pharmaceutical compositions comprising voriconazole
BR112014017751B1 (pt) 2012-01-20 2021-12-07 Mycovia Pharmaceuticals, Inc Compostos inibidores de metaloenzima, composições compreendendo os ditos compostos e uso dos ditos compostos
HRP20231151T1 (hr) * 2012-03-19 2024-01-05 Cidara Therapeutics, Inc. Režimi za doziranje spojeva iz klase ehinokandina
CN103864844B (zh) * 2012-12-09 2016-10-05 正大天晴药业集团股份有限公司 一种福司氟康唑的制备方法
CN103304600B (zh) * 2013-03-04 2018-05-25 陕西合成药业股份有限公司 一种伏立康唑磷酸酯三水合物及其制备方法和用途
EP2968595A2 (en) 2013-03-14 2016-01-20 Fresenius Kabi USA LLC Voriconazole formulations
RU2719579C2 (ru) * 2013-03-14 2020-04-21 Сидара Терапьютикс, Инк. Режимы дозирования для соединений класса эхинокандинов
US20160128944A1 (en) 2013-06-04 2016-05-12 Vyome Biosciences Pvt. Ltd. Coated particles and compositions comprising same
CN103524560A (zh) * 2013-09-28 2014-01-22 陕西合成药业有限公司 伏立康磷酸酯钠水合物及其多晶型
CN104650140B (zh) * 2013-11-18 2017-11-10 正大天晴药业集团股份有限公司 一种高纯度福司氟康唑的制备方法
BR112016017690A2 (pt) 2014-01-29 2017-08-08 Vyome Biosciences Pvt Ltd Tratamentos para acne resistente
CN104860992A (zh) * 2014-02-25 2015-08-26 陕西合成药业股份有限公司 一种高纯度福司氟康唑制备方法
CN105985377A (zh) * 2015-02-09 2016-10-05 陕西合成药业股份有限公司 一种福司氟康唑盐水合物及其制备方法
CN106279280A (zh) * 2015-05-25 2017-01-04 西藏卫信康医药股份有限公司 一种化合物及其制备方法和应用
CN106518922A (zh) * 2015-09-12 2017-03-22 陕西合成药业股份有限公司 一种三唑类化合物及其制备方法和用途
CN106546668A (zh) * 2015-09-22 2017-03-29 陕西合成药业股份有限公司 一种分离福司氟康唑或其药用盐有关物质的hplc方法
CN105237569B (zh) * 2015-10-21 2017-07-25 西南科技大学 一种制备2，4‑二氟‑α，α‑二（1氢‑1，2，4‑三唑‑1‑基甲基）苯甲醇磷酸二苄酯的合成方法
CN105753902B (zh) * 2016-04-11 2017-08-25 浙江诚意药业股份有限公司 一种福司氟康唑的制备方法
CN108676031A (zh) * 2018-05-29 2018-10-19 重庆威鹏药业有限公司 水溶性三唑类抗真菌膦酸化合物及其制备方法和应用
CN111171075B (zh) * 2020-04-03 2022-07-12 北京四环生物制药有限公司 一种福司氟康唑的制备方法

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US4528284A (en) * 1982-10-15 1985-07-09 Ciba-Geigy Corporation Fungicidal 2-(azolylmethyl-1'-yl)-2-aryl-2-(cyano, alkoxycarbonyl, alkylthiocarbonyl and aminocarbonyl)-2-phosphorus acid esters
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Also Published As

Publication number Publication date
RS49526B (sr) 2006-12-15
SK283136B6 (sk) 2003-03-04
CN1085213C (zh) 2002-05-22
HN1997000012A (es) 1997-06-26
NO323771B1 (no) 2007-07-02
CA2240777C (en) 2002-06-11
AP9700923A0 (en) 1997-01-31
GB9602080D0 (en) 1996-04-03
HK1018217A1 (en) 1999-12-17
DZ2172A1 (fr) 2002-12-01
CZ242098A3 (cs) 1999-05-12
US20040236105A1 (en) 2004-11-25
IL124865A (en) 2002-03-10
BG63946B1 (bg) 2003-07-31
SA97170578B1 (ar) 2006-01-28
SK102298A3 (en) 1999-08-06
KR100283546B1 (ko) 2001-04-02
JP2959846B2 (ja) 1999-10-06
ES2175336T3 (es) 2002-11-16
AU709781B2 (en) 1999-09-09
HUP9900949A2 (hu) 2001-05-28
UA46828C2 (uk) 2002-06-17
EP0880533B1 (en) 2002-06-12
JPH10512599A (ja) 1998-12-02
MY116849A (en) 2004-04-30
DK0880533T3 (da) 2002-07-15
TR199801440T2 (xx) 1998-10-21
EP0880533A1 (en) 1998-12-02
YU2997A (sh) 2000-10-30
US20050130940A1 (en) 2005-06-16
DE69713284T2 (de) 2003-03-27
BG102603A (en) 1999-03-31
CA2240777A1 (en) 1997-08-07
AU1598597A (en) 1997-08-22
US20070027115A1 (en) 2007-02-01
ATE219089T1 (de) 2002-06-15
KR19990082233A (ko) 1999-11-25
BR9707257A (pt) 1999-04-06
NO983560D0 (no) 1998-08-03
ZA97826B (en) 1998-07-31
US6977302B2 (en) 2005-12-20
HRP970063A2 (en) 1998-06-30
PL187237B1 (pl) 2004-06-30
DE69713284D1 (de) 2002-07-18
TW434247B (en) 2001-05-16
OA10711A (en) 2001-06-04
WO1997028169A1 (en) 1997-08-07
CZ291431B6 (cs) 2003-03-12
PT880533E (pt) 2002-09-30
SI0880533T1 (en) 2002-08-31
HUP9900949A3 (en) 2001-08-28
NZ330654A (en) 1999-08-30
NO983560L (no) 1998-08-03
ID15858A (id) 1997-08-14
PL328436A1 (en) 1999-02-01
US6790957B2 (en) 2004-09-14
GT199700016A (es) 1998-07-24
CO4761066A1 (es) 1999-04-27
AP678A (en) 1998-09-28
RU2176244C2 (ru) 2001-11-27
IL133135A (en) 2003-07-06
IL124865A0 (en) 1999-01-26
HU226133B1 (en) 2008-05-28
IS1995B (is) 2005-03-15
TNSN97023A1 (fr) 2005-03-15
IS4785A (is) 1998-06-26
CN1210540A (zh) 1999-03-10
HRP970063B1 (en) 2001-12-31
US20030144250A1 (en) 2003-07-31

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