IL133135A - Triazole dihydrogen phosphate derivatives - Google Patents

Triazole dihydrogen phosphate derivatives

Info

Publication number
IL133135A
IL133135A IL13313598A IL13313598A IL133135A IL 133135 A IL133135 A IL 133135A IL 13313598 A IL13313598 A IL 13313598A IL 13313598 A IL13313598 A IL 13313598A IL 133135 A IL133135 A IL 133135A
Authority
IL
Israel
Prior art keywords
triazole
dihydrogen phosphate
phosphate derivatives
derivatives
dihydrogen
Prior art date
Application number
IL13313598A
Other languages
English (en)
Original Assignee
Pfizer Res And Dev Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res And Dev Company filed Critical Pfizer Res And Dev Company
Priority to IL13313598A priority Critical patent/IL133135A/xx
Publication of IL133135A publication Critical patent/IL133135A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
    • C07F9/6518—Five-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13313598A 1996-02-02 1998-06-11 Triazole dihydrogen phosphate derivatives IL133135A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL13313598A IL133135A (en) 1996-02-02 1998-06-11 Triazole dihydrogen phosphate derivatives

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9602080.5A GB9602080D0 (en) 1996-02-02 1996-02-02 Pharmaceutical compounds
IL12486597A IL124865A (en) 1996-02-02 1997-01-27 Derivatives of triazole dihydrogen phosphate, their preparation and pharmaceutical preparations containing them
IL13313598A IL133135A (en) 1996-02-02 1998-06-11 Triazole dihydrogen phosphate derivatives

Publications (1)

Publication Number Publication Date
IL133135A true IL133135A (en) 2003-07-06

Family

ID=10787975

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12486597A IL124865A (en) 1996-02-02 1997-01-27 Derivatives of triazole dihydrogen phosphate, their preparation and pharmaceutical preparations containing them
IL13313598A IL133135A (en) 1996-02-02 1998-06-11 Triazole dihydrogen phosphate derivatives
IL13313599A IL133135A0 (en) 1996-02-02 1999-11-25 Triazole dihydrogen phosphate derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL12486597A IL124865A (en) 1996-02-02 1997-01-27 Derivatives of triazole dihydrogen phosphate, their preparation and pharmaceutical preparations containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL13313599A IL133135A0 (en) 1996-02-02 1999-11-25 Triazole dihydrogen phosphate derivatives

Country Status (43)

Country Link
US (4) US6790957B2 (xx)
EP (1) EP0880533B1 (xx)
JP (1) JP2959846B2 (xx)
KR (1) KR100283546B1 (xx)
CN (1) CN1085213C (xx)
AP (1) AP678A (xx)
AT (1) ATE219089T1 (xx)
AU (1) AU709781B2 (xx)
BG (1) BG63946B1 (xx)
BR (1) BR9707257A (xx)
CA (1) CA2240777C (xx)
CO (1) CO4761066A1 (xx)
CZ (1) CZ291431B6 (xx)
DE (1) DE69713284T2 (xx)
DK (1) DK0880533T3 (xx)
DZ (1) DZ2172A1 (xx)
ES (1) ES2175336T3 (xx)
GB (1) GB9602080D0 (xx)
GT (1) GT199700016A (xx)
HK (1) HK1018217A1 (xx)
HN (1) HN1997000012A (xx)
HR (1) HRP970063B1 (xx)
HU (1) HU226133B1 (xx)
ID (1) ID15858A (xx)
IL (3) IL124865A (xx)
IS (1) IS1995B (xx)
MY (1) MY116849A (xx)
NO (1) NO323771B1 (xx)
NZ (1) NZ330654A (xx)
OA (1) OA10711A (xx)
PL (1) PL187237B1 (xx)
PT (1) PT880533E (xx)
RS (1) RS49526B (xx)
RU (1) RU2176244C2 (xx)
SA (1) SA97170578B1 (xx)
SI (1) SI0880533T1 (xx)
SK (1) SK283136B6 (xx)
TN (1) TNSN97023A1 (xx)
TR (1) TR199801440T2 (xx)
TW (1) TW434247B (xx)
UA (1) UA46828C2 (xx)
WO (1) WO1997028169A1 (xx)
ZA (1) ZA97826B (xx)

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US6362172B2 (en) * 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6448401B1 (en) * 2000-11-20 2002-09-10 Bristol-Myers Squibb Company Process for water soluble azole compounds
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US7323572B2 (en) 2002-07-16 2008-01-29 Pfizer Inc Process for controlling the hydrate mix of a compound
EP1646284A4 (en) * 2003-07-18 2008-09-24 Rhode Island Education AZOL DERIVATIVES AND METHOD FOR THEIR PREPARATION
CN101132802A (zh) * 2004-03-24 2008-02-27 法斯根有限责任公司 通过药理学抑制amp-活化的蛋白激酶的神经保护的新方法
CN1303073C (zh) * 2005-05-31 2007-03-07 中国人民解放军第二军医大学 取代三唑酮苄胺三唑醇类抗真菌化合物及其制备方法
US7803949B2 (en) * 2005-12-20 2010-09-28 Eisai R&D Management Co., Ltd. Process for preparation of water-soluble azole prodrugs
PL1968990T3 (pl) 2005-12-27 2015-06-30 Otsuka Pharma Co Ltd Rozpuszczalny w wodzie związek benzoazepinowy i jego kompozycja farmaceutyczna
CN101389333A (zh) * 2006-02-22 2009-03-18 卫材R&D管理有限公司 稳定化药物组合物
WO2009129300A2 (en) * 2008-04-15 2009-10-22 Schering Corporation High density compositions containing posaconazole and formulations comprising the same
CN101575330B (zh) * 2008-05-05 2012-10-31 丽珠医药集团股份有限公司 伏立康唑广谱抗真菌药物化合物、其组合物及用途
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EP2723452A2 (en) 2011-06-22 2014-04-30 Vyome Biosciences Pvt Ltd Conjugate-based antifungal and antibacterial prodrugs
EP2561863A1 (en) 2011-08-22 2013-02-27 Farmaprojects, S.A.U. Pharmaceutical compositions comprising voriconazole
KR102061137B1 (ko) * 2012-01-20 2019-12-31 마이코비아 파마슈티컬즈, 인코포레이티드 금속효소 억제제 화합물
DK3677252T3 (da) * 2012-03-19 2023-10-02 Cidara Therapeutics Inc Doseringsregimer for echinocandin-klasse forbindelser
CN103864844B (zh) * 2012-12-09 2016-10-05 正大天晴药业集团股份有限公司 一种福司氟康唑的制备方法
CN103304600B (zh) * 2013-03-04 2018-05-25 陕西合成药业股份有限公司 一种伏立康唑磷酸酯三水合物及其制备方法和用途
CA2904670A1 (en) 2013-03-14 2014-09-13 Fresenius Kabi Usa, Llc Voriconazole formulations
RU2719579C2 (ru) * 2013-03-14 2020-04-21 Сидара Терапьютикс, Инк. Режимы дозирования для соединений класса эхинокандинов
US20160128944A1 (en) 2013-06-04 2016-05-12 Vyome Biosciences Pvt. Ltd. Coated particles and compositions comprising same
CN103524560A (zh) * 2013-09-28 2014-01-22 陕西合成药业有限公司 伏立康磷酸酯钠水合物及其多晶型
CN104650140B (zh) * 2013-11-18 2017-11-10 正大天晴药业集团股份有限公司 一种高纯度福司氟康唑的制备方法
AU2015212312A1 (en) 2014-01-29 2016-08-18 Vyome Therapeutics Limited Treatments for resistant acne
CN104860992A (zh) * 2014-02-25 2015-08-26 陕西合成药业股份有限公司 一种高纯度福司氟康唑制备方法
CN105985377A (zh) * 2015-02-09 2016-10-05 陕西合成药业股份有限公司 一种福司氟康唑盐水合物及其制备方法
CN106279280A (zh) * 2015-05-25 2017-01-04 西藏卫信康医药股份有限公司 一种化合物及其制备方法和应用
CN106518922A (zh) * 2015-09-12 2017-03-22 陕西合成药业股份有限公司 一种三唑类化合物及其制备方法和用途
CN106546668A (zh) * 2015-09-22 2017-03-29 陕西合成药业股份有限公司 一种分离福司氟康唑或其药用盐有关物质的hplc方法
CN105237569B (zh) * 2015-10-21 2017-07-25 西南科技大学 一种制备2，4‑二氟‑α，α‑二（1氢‑1，2，4‑三唑‑1‑基甲基）苯甲醇磷酸二苄酯的合成方法
CN105753902B (zh) * 2016-04-11 2017-08-25 浙江诚意药业股份有限公司 一种福司氟康唑的制备方法
CN108676031A (zh) * 2018-05-29 2018-10-19 重庆威鹏药业有限公司 水溶性三唑类抗真菌膦酸化合物及其制备方法和应用
CN111171075B (zh) * 2020-04-03 2022-07-12 北京四环生物制药有限公司 一种福司氟康唑的制备方法

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Also Published As

Publication number Publication date
AP9700923A0 (en) 1997-01-31
PT880533E (pt) 2002-09-30
CZ291431B6 (cs) 2003-03-12
NO323771B1 (no) 2007-07-02
AU709781B2 (en) 1999-09-09
SA97170578B1 (ar) 2006-01-28
HRP970063A2 (en) 1998-06-30
IS4785A (is) 1998-06-26
EP0880533A1 (en) 1998-12-02
HN1997000012A (es) 1997-06-26
HUP9900949A2 (hu) 2001-05-28
WO1997028169A1 (en) 1997-08-07
PL328436A1 (en) 1999-02-01
KR100283546B1 (ko) 2001-04-02
ID15858A (id) 1997-08-14
UA46828C2 (uk) 2002-06-17
RS49526B (sr) 2006-12-15
DE69713284T2 (de) 2003-03-27
CZ242098A3 (cs) 1999-05-12
DK0880533T3 (da) 2002-07-15
HRP970063B1 (en) 2001-12-31
US20030144250A1 (en) 2003-07-31
KR19990082233A (ko) 1999-11-25
HK1018217A1 (en) 1999-12-17
BR9707257A (pt) 1999-04-06
ATE219089T1 (de) 2002-06-15
PL187237B1 (pl) 2004-06-30
AP678A (en) 1998-09-28
IL124865A (en) 2002-03-10
CN1210540A (zh) 1999-03-10
IS1995B (is) 2005-03-15
NO983560D0 (no) 1998-08-03
CN1085213C (zh) 2002-05-22
CA2240777C (en) 2002-06-11
SK102298A3 (en) 1999-08-06
US6790957B2 (en) 2004-09-14
OA10711A (en) 2001-06-04
EP0880533B1 (en) 2002-06-12
US20040236105A1 (en) 2004-11-25
US20050130940A1 (en) 2005-06-16
CA2240777A1 (en) 1997-08-07
DE69713284D1 (de) 2002-07-18
ZA97826B (en) 1998-07-31
NZ330654A (en) 1999-08-30
MY116849A (en) 2004-04-30
SK283136B6 (sk) 2003-03-04
TR199801440T2 (xx) 1998-10-21
TNSN97023A1 (fr) 2005-03-15
TW434247B (en) 2001-05-16
GB9602080D0 (en) 1996-04-03
ES2175336T3 (es) 2002-11-16
US6977302B2 (en) 2005-12-20
JPH10512599A (ja) 1998-12-02
BG63946B1 (bg) 2003-07-31
BG102603A (en) 1999-03-31
GT199700016A (es) 1998-07-24
IL124865A0 (en) 1999-01-26
JP2959846B2 (ja) 1999-10-06
CO4761066A1 (es) 1999-04-27
HU226133B1 (en) 2008-05-28
NO983560L (no) 1998-08-03
AU1598597A (en) 1997-08-22
IL133135A0 (en) 2001-03-19
DZ2172A1 (fr) 2002-12-01
YU2997A (sh) 2000-10-30
HUP9900949A3 (en) 2001-08-28
SI0880533T1 (en) 2002-08-31
US20070027115A1 (en) 2007-02-01
RU2176244C2 (ru) 2001-11-27

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