IL129724A - Crystalline production of benzimidazole derivatives - Google Patents

Crystalline production of benzimidazole derivatives

Info

Publication number
IL129724A
IL129724A IL12972497A IL12972497A IL129724A IL 129724 A IL129724 A IL 129724A IL 12972497 A IL12972497 A IL 12972497A IL 12972497 A IL12972497 A IL 12972497A IL 129724 A IL129724 A IL 129724A
Authority
IL
Israel
Prior art keywords
compound
alkoxy
group
substituted
methyl
Prior art date
Application number
IL12972497A
Other languages
English (en)
Hebrew (he)
Other versions
IL129724A0 (en
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17920069&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL129724(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of IL129724A0 publication Critical patent/IL129724A0/xx
Publication of IL129724A publication Critical patent/IL129724A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL12972497A 1996-11-14 1997-11-13 Crystalline production of benzimidazole derivatives IL129724A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30336196 1996-11-14
PCT/JP1997/004136 WO1998021201A1 (fr) 1996-11-14 1997-11-13 Cristaux de derives benzimidazole et leur production

Publications (2)

Publication Number Publication Date
IL129724A0 IL129724A0 (en) 2000-02-29
IL129724A true IL129724A (en) 2004-02-19

Family

ID=17920069

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12972497A IL129724A (en) 1996-11-14 1997-11-13 Crystalline production of benzimidazole derivatives

Country Status (19)

Country Link
US (1) US6002011A (fr)
EP (1) EP0944617B1 (fr)
KR (1) KR100519576B1 (fr)
CN (2) CN1171885C (fr)
AT (1) ATE240314T1 (fr)
AU (1) AU731776B2 (fr)
CA (1) CA2269053C (fr)
DE (1) DE69722027T2 (fr)
DK (1) DK0944617T3 (fr)
ES (1) ES2199356T3 (fr)
HK (1) HK1020194A1 (fr)
ID (1) ID21547A (fr)
IL (1) IL129724A (fr)
NZ (1) NZ335145A (fr)
PT (1) PT944617E (fr)
TR (1) TR199901055T2 (fr)
TW (1) TW385306B (fr)
WO (1) WO1998021201A1 (fr)
ZA (1) ZA9710255B (fr)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
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TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives
UA72748C2 (en) 1998-11-10 2005-04-15 Astrazeneca Ab A novel crystalline form of omeprazole
IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
JP3926936B2 (ja) * 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
DE10080190D2 (de) * 1999-02-04 2002-01-24 Joern Bullerdiek Mittel zur Prävention und/oder Behandlung einer Gewebeveränderung mesenchymalen Ursprungs
TWI289557B (en) * 1999-06-17 2007-11-11 Takeda Chemical Industries Ltd A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
PL333847A1 (en) * 1999-06-18 2001-01-02 Inst Farmaceutyczny Crystalline forms of lansoprozole and method of obtaining lansoprazole in pharmacologically advanthageous crystalline form
WO2001002389A1 (fr) * 1999-06-30 2001-01-11 Takeda Chemical Industries, Ltd. Cristaux de composes benzimidazole
KR101035534B1 (ko) 2000-05-15 2011-05-23 다케다 야쿠힌 고교 가부시키가이샤 결정의 제조방법
CA2417311C (fr) * 2000-08-04 2012-07-10 Takeda Chemical Industries, Ltd. Sels cristallins de metal alcalin et de lansoprazole et methode de production et utilisation connexes
US7396841B2 (en) 2000-08-18 2008-07-08 Takeda Pharmaceutical Company Limited Injections
KR100887912B1 (ko) 2000-12-01 2009-03-12 다케다 야쿠힌 고교 가부시키가이샤 (ｒ)- 또는 (ｓ)-란소프라졸의 결정화 방법
DE10140492A1 (de) 2001-08-17 2003-08-14 Gruenenthal Gmbh Hydrate von gegebenenfalls substituierten 2-(2-Pyridinyl)methylthio-1H-benzimidazolen und Verfahren zu ihrer Herstellung
CN100562317C (zh) 2001-10-17 2009-11-25 武田药品工业株式会社 含大量酸不稳定药物的颗粒
IL163594A0 (en) * 2002-02-19 2005-12-18 Teva Pharma Processes for desolvating solvates of atorvastatinhemi-calcium and atorvastatin hemi-calcium essentially free of organic solvent
KR20040093187A (ko) * 2002-03-27 2004-11-04 테바 파마슈티컬 인더스트리즈 리미티드 란소프라졸 다형 및 그것의 제조 방법
KR100873419B1 (ko) * 2002-06-18 2008-12-11 페어차일드코리아반도체 주식회사 높은 항복 전압, 낮은 온 저항 및 작은 스위칭 손실을갖는 전력용 반도체 소자
TW200410955A (en) 2002-07-29 2004-07-01 Altana Pharma Ag Novel salt of (S)-PANTOPRAZOLE
PT1501824E (pt) * 2002-08-21 2007-11-28 Teva Pharma Método para purificação de lansoprazole
EP1837335A1 (fr) * 2002-08-21 2007-09-26 Teva Pharmaceutical Industries Ltd Procédé de purification du lansoprazole
US8697094B2 (en) 2002-10-16 2014-04-15 Takeda Pharmaceutical Company Limited Stable solid preparations
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
EP1743893A1 (fr) 2002-11-18 2007-01-17 Teva Pharmaceutical Industries Ltd. Lansoprazole stable contenant plus de 500 parties par million, jusqu'à environ 3000 parties par million d'eau et plus de 200 parties par million, jusqu'à environ 5000 parties par million d'alcool
DE03789888T1 (de) * 2002-11-18 2005-08-18 Teva Pharmaceutical Industries Ltd. Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol
US7678816B2 (en) * 2003-02-05 2010-03-16 Teva Pharmaceutical Industries Ltd. Method of stabilizing lansoprazole
US7005732B2 (en) * 2003-10-21 2006-02-28 Honeywell International Inc. Methods and systems for providing MEMS devices with a top cap and upper sense plate
TW200526268A (en) * 2003-12-17 2005-08-16 Takeda Pharmaceutical Injectable composition
SE0400410D0 (sv) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
JP5563735B2 (ja) 2004-06-16 2014-07-30 タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド Ｐｐｉ多回剤形
JP5173191B2 (ja) 2004-09-13 2013-03-27 武田薬品工業株式会社 酸化化合物の製造方法及び製造装置
EP1681056A1 (fr) * 2005-01-14 2006-07-19 Krka Tovarna Zdravil, D.D., Novo Mesto Procédé de préparation du lansoprazole
WO2006090845A1 (fr) 2005-02-25 2006-08-31 Takeda Pharmaceutical Company Limited Procédé de fabrication de granulés
EP1889841A4 (fr) * 2005-06-07 2010-04-07 Takeda Pharmaceutical Cristal d'un sel d'un compose de benzimidazole
CA2611917A1 (fr) * 2005-06-13 2006-12-21 Takeda Pharmaceutical Company Limited Produit d'injection
ZA200805646B (en) 2005-12-28 2009-12-30 Takeda Pharmaceutical Controlled release solid preparation
KR100758600B1 (ko) * 2006-01-05 2007-09-13 주식회사 대웅제약 란소프라졸 결정형 ａ의 제조방법
US8129536B2 (en) * 2006-09-22 2012-03-06 Orchid Chemicals & Pharmaceuticals Limited Method for the purification of lansoprazole
EP2089379A4 (fr) * 2006-12-07 2010-04-21 Hetero Drugs Ltd Nouvelle forme cristalline du lansoprazole
ITMI20062481A1 (it) * 2006-12-22 2008-06-23 Recordati Chem Pharm Processo per la preparazione di lansoprazolo forma i microcristallino
JP5366558B2 (ja) 2006-12-28 2013-12-11 武田薬品工業株式会社 口腔内崩壊性固形製剤
US20100286400A1 (en) * 2007-12-31 2010-11-11 Takeda Pharmaceutical Company Limited Crystalline solvated forms of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole
EP2262790B1 (fr) * 2008-03-10 2017-06-07 Takeda Pharmaceutical Company Limited Cristal de composé de benzimidazole
WO2011004387A2 (fr) 2009-06-18 2011-01-13 Matrix Laboratories Ltd Procédé de préparation de formes polymorphes du dexlansoprazole
US20130012714A1 (en) * 2010-02-11 2013-01-10 Orchid Chemicals & Pharmaceuticals Limited Novel solvate of dexlansoprazole
MX2013006247A (es) 2010-12-03 2014-01-31 Takeda Pharmaceutical Tableta oralmente desintegradora.
WO2012091153A2 (fr) 2010-12-27 2012-07-05 Takeda Pharmaceutical Company Limited Comprimé orodispersible
CN103012369B (zh) * 2011-05-23 2014-04-23 中山大学 兰索拉唑n晶型及其制备方法和应用
CN102180866B (zh) * 2011-05-23 2013-03-13 中山大学 兰索拉唑晶型及其制备方法和应用
JP5925318B2 (ja) 2011-11-30 2016-05-25 武田薬品工業株式会社 有核錠
US9119769B2 (en) 2011-12-30 2015-09-01 The Curators Of The University Of Missouri Method for transforming pharmaceutical crystal forms
US10004691B2 (en) 2013-05-21 2018-06-26 Takeda Pharmaceuticals Company Limited Orally disintegrable tablet
CN103539729A (zh) * 2013-10-14 2014-01-29 安徽国星生物化学有限公司 一种氯甲基吡啶衍生物的工业化生产方法
CN103539728A (zh) * 2013-10-14 2014-01-29 安徽国星生物化学有限公司 一种拉唑类药物中间体氯甲基吡啶衍生物的合成方法
CN104829594A (zh) * 2015-05-15 2015-08-12 苗怡文 一种治疗胃溃疡的药物兰索拉唑化合物
CN104817492B (zh) * 2015-05-22 2018-05-18 抚州三和医药化工有限公司 兰索拉唑中间体2-羟甲基-3-甲基-4-(2,2,2-三氟乙氧基）吡啶的分离纯化方法
KR102649498B1 (ko) 2023-12-06 2024-03-20 거산해운(주) 선사별 실시간 통합 예약 정보를 기반으로 한 화주의 해상 운송 예약 자동화 플랫폼 서비스 제공 방법, 장치 및 시스템

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Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
DK171989B1 (da) * 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
DE4018642C2 (de) * 1990-06-11 1993-11-25 Byk Gulden Lomberg Chem Fab Neue Salzform des 5-Difluormethoxy-2-[(3,4-dimethoxy-2-pyridyl) methylsulfinyl]-1H-benzimitazol-Natriumsalzes
SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
US5374730A (en) * 1993-11-04 1994-12-20 Torcan Chemical Ltd. Preparation of omeprazole and lansoprazole
GB2297550B (en) * 1995-02-06 1997-04-09 Smithkline Beecham Plc Paroxetine hydrochloride anhydrate substantially free of bound organic solvent
TW385306B (en) * 1996-11-14 2000-03-21 Takeda Chemical Industries Ltd Method for producing crystals of benzimidazole derivatives

Also Published As

Publication number Publication date
KR100519576B1 (ko) 2005-10-07
AU4965297A (en) 1998-06-03
KR20000053158A (ko) 2000-08-25
DE69722027D1 (de) 2003-06-18
EP0944617B1 (fr) 2003-05-14
PT944617E (pt) 2003-08-29
CA2269053C (fr) 2006-07-18
DE69722027T2 (de) 2004-03-25
IL129724A0 (en) 2000-02-29
TR199901055T2 (xx) 1999-07-21
CN1616457A (zh) 2005-05-18
CN1171885C (zh) 2004-10-20
CN100355749C (zh) 2007-12-19
ES2199356T3 (es) 2004-02-16
ZA9710255B (en) 1999-05-13
CA2269053A1 (fr) 1998-05-22
EP0944617A1 (fr) 1999-09-29
WO1998021201A1 (fr) 1998-05-22
DK0944617T3 (da) 2003-09-01
HK1020194A1 (en) 2000-03-31
CN1237167A (zh) 1999-12-01
ID21547A (id) 1999-06-24
TW385306B (en) 2000-03-21
NZ335145A (en) 2000-12-22
US6002011A (en) 1999-12-14
AU731776B2 (en) 2001-04-05
ATE240314T1 (de) 2003-05-15

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Legal Events

Date Code Title Description
NP Permission for amending the patent specification granted (section 66, patents law 1967)
FF Patent granted
KB Patent renewed
KB Patent renewed
EXP Patent expired