IL127342A - A method for detecting nucleic acid that includes methylated GPC, a kit for using the method and a method for detecting a disease related to the methylation of nucleic acid - Google Patents

A method for detecting nucleic acid that includes methylated GPC, a kit for using the method and a method for detecting a disease related to the methylation of nucleic acid

Info

Publication number
IL127342A
IL127342A IL12734297A IL12734297A IL127342A IL 127342 A IL127342 A IL 127342A IL 12734297 A IL12734297 A IL 12734297A IL 12734297 A IL12734297 A IL 12734297A IL 127342 A IL127342 A IL 127342A
Authority
IL
Israel
Prior art keywords
nucleic acid
methylated
primers
dna
cpg
Prior art date
Application number
IL12734297A
Other languages
English (en)
Hebrew (he)
Other versions
IL127342A0 (en
Original Assignee
Univ Johns Hopkins Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/656,716 external-priority patent/US5786146A/en
Application filed by Univ Johns Hopkins Med filed Critical Univ Johns Hopkins Med
Publication of IL127342A0 publication Critical patent/IL127342A0/xx
Publication of IL127342A publication Critical patent/IL127342A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
IL12734297A 1996-06-03 1997-06-03 A method for detecting nucleic acid that includes methylated GPC, a kit for using the method and a method for detecting a disease related to the methylation of nucleic acid IL127342A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/656,716 US5786146A (en) 1996-06-03 1996-06-03 Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US08/835,728 US6017704A (en) 1996-06-03 1997-04-11 Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
PCT/US1997/009533 WO1997046705A1 (fr) 1996-06-03 1997-06-03 Detection specifique de la methylation

Publications (2)

Publication Number Publication Date
IL127342A0 IL127342A0 (en) 1999-10-28
IL127342A true IL127342A (en) 2002-07-25

Family

ID=27097252

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12734297A IL127342A (en) 1996-06-03 1997-06-03 A method for detecting nucleic acid that includes methylated GPC, a kit for using the method and a method for detecting a disease related to the methylation of nucleic acid

Country Status (11)

Country Link
US (2) US6017704A (fr)
EP (2) EP1690948A3 (fr)
JP (2) JP3612080B2 (fr)
AT (1) ATE326549T1 (fr)
CA (1) CA2257104C (fr)
DE (1) DE69735894T2 (fr)
DK (1) DK0954608T3 (fr)
ES (1) ES2264165T3 (fr)
IL (1) IL127342A (fr)
PT (1) PT954608E (fr)
WO (1) WO1997046705A1 (fr)

Families Citing this family (293)

* Cited by examiner, † Cited by third party
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DE19905082C1 (de) * 1999-01-29 2000-05-18 Epigenomics Gmbh Verfahren zur Identifikation von Cytosin-Methylierungsmustern in genomischen DNA-Proben
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EP0954608A1 (fr) 1999-11-10
JP3612080B2 (ja) 2005-01-19
JP2000511776A (ja) 2000-09-12
WO1997046705A1 (fr) 1997-12-11
ES2264165T3 (es) 2006-12-16
EP0954608B1 (fr) 2006-05-17
EP1690948A2 (fr) 2006-08-16
DK0954608T3 (da) 2006-08-21
EP1690948A3 (fr) 2006-11-22
JP2004290200A (ja) 2004-10-21
JP3725535B2 (ja) 2005-12-14
US6265171B1 (en) 2001-07-24
PT954608E (pt) 2006-08-31
DE69735894D1 (de) 2006-06-22
US6017704A (en) 2000-01-25
DE69735894T2 (de) 2007-04-19
CA2257104C (fr) 2008-01-29
IL127342A0 (en) 1999-10-28
EP0954608A4 (fr) 2003-09-10
CA2257104A1 (fr) 1997-12-11
ATE326549T1 (de) 2006-06-15

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