ATE438740T1 - Verfahren und nukleinsäuren zur analyse von mit der prognose von störungen der proliferation von prostatazellen assoziierter genexpression - Google Patents
Verfahren und nukleinsäuren zur analyse von mit der prognose von störungen der proliferation von prostatazellen assoziierter genexpressionInfo
- Publication number
- ATE438740T1 ATE438740T1 AT05853011T AT05853011T ATE438740T1 AT E438740 T1 ATE438740 T1 AT E438740T1 AT 05853011 T AT05853011 T AT 05853011T AT 05853011 T AT05853011 T AT 05853011T AT E438740 T1 ATE438740 T1 AT E438740T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acids
- disorders
- proliferation
- prediction
- gene expression
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63325004P | 2004-12-02 | 2004-12-02 | |
US63242604P | 2004-12-02 | 2004-12-02 | |
US66222005P | 2005-03-14 | 2005-03-14 | |
US72312505P | 2005-10-03 | 2005-10-03 | |
US72305405P | 2005-10-03 | 2005-10-03 | |
US74073605P | 2005-11-30 | 2005-11-30 | |
PCT/US2005/043974 WO2006071466A2 (en) | 2004-12-02 | 2005-12-02 | Methods and nucleic acids for the analysis of gene expression associated with the prognosis of prostate cell proliferative disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE438740T1 true ATE438740T1 (de) | 2009-08-15 |
Family
ID=39661458
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05853011T ATE438740T1 (de) | 2004-12-02 | 2005-12-02 | Verfahren und nukleinsäuren zur analyse von mit der prognose von störungen der proliferation von prostatazellen assoziierter genexpression |
Country Status (9)
Country | Link |
---|---|
US (2) | US20090197250A1 (de) |
EP (5) | EP1831399B1 (de) |
JP (2) | JP5745202B2 (de) |
AT (1) | ATE438740T1 (de) |
AU (1) | AU2005322435B2 (de) |
CA (1) | CA2593546A1 (de) |
DE (1) | DE602005015893D1 (de) |
ES (2) | ES2534139T3 (de) |
WO (1) | WO2006071466A2 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6331393B1 (en) | 1999-05-14 | 2001-12-18 | University Of Southern California | Process for high-throughput DNA methylation analysis |
US7951563B2 (en) * | 2005-04-15 | 2011-05-31 | Epigenomics Ag | Methods and nucleic acids for analysis of cellular proliferative disorders |
ES2404066T3 (es) * | 2005-09-21 | 2013-05-23 | Epigenomics Ag | Marcadores para la predicción del resultado de un tratamiento con antraciclina |
WO2007039291A2 (en) * | 2005-10-03 | 2007-04-12 | Epigenomics Ag | Methods, apparatus and nomograms to determine prostate cancer progression |
EP1943356B1 (de) * | 2005-10-03 | 2014-05-14 | Epigenomics AG | Verfahren und nukleinsäuren zur analyse der genexpression in zusammenhang mit der prognose von zellproliferationsstörungen |
US7770717B2 (en) * | 2005-10-12 | 2010-08-10 | Scanvaegt International A/S | Device for transfer of items |
US20090275021A1 (en) * | 2005-11-27 | 2009-11-05 | Osnat Sella-Tavor | Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis |
GB0625321D0 (en) * | 2006-12-19 | 2007-01-24 | Univ Surrey | Cancer biomarker |
US20090062645A1 (en) * | 2007-09-03 | 2009-03-05 | Jens Fehre | Method for diagnosis and treatment of prostate cancer |
EP2261366B1 (de) * | 2007-11-23 | 2016-01-27 | Epigenomics AG | Verfahren und Nukleinsäuren zur Analyse der CpG Methylierung, die mit der Entwicklung von mit der prostatischen Zellproliferation assozierten Krankheiten einhergeht |
WO2009074328A2 (en) * | 2007-12-11 | 2009-06-18 | Epigenomics Ag | Methods and nucleic acids for analyses of lung carcinoma |
JP5513375B2 (ja) * | 2008-05-07 | 2014-06-04 | 北海道公立大学法人 札幌医科大学 | 癌の検出方法および検出用キット、ならびに癌治療剤 |
US9315802B2 (en) | 2009-12-30 | 2016-04-19 | Quest Diagnostics Investments Incorporated | RNA isolation from soluble urine fractions |
DE102010028105A1 (de) * | 2010-04-22 | 2011-10-27 | Siemens Aktiengesellschaft | Verfahren, Vorrichtung und Gerätesystem für die Therapie von Prostatakrebs |
WO2012092490A1 (en) | 2010-12-30 | 2012-07-05 | Quest Diagnostics Investments Incorporated | Diagnosis of prostate cancer |
EP2514836B1 (de) * | 2011-04-19 | 2016-06-29 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Prostatakrebsmarker |
US9598735B2 (en) * | 2012-11-14 | 2017-03-21 | JBS Science Inc. | Detection of a panel of urine DNA markers for HCC screening and disease management |
KR101467289B1 (ko) * | 2013-01-22 | 2014-12-02 | 한국원자력의학원 | Wdfy3를 측정하는 제제를 포함하는 방사선 저항성 또는 민감성 진단용 조성물 및 이의 용도 |
US20150010518A1 (en) * | 2013-07-03 | 2015-01-08 | The University Of British Columbia | Nr2e1 mini-promoters |
WO2015023285A1 (en) * | 2013-08-15 | 2015-02-19 | Xia Xueliang James | Biomarkers for use in colorectal cancer |
JP6427750B2 (ja) * | 2013-10-02 | 2018-11-28 | コニカミノルタ株式会社 | Cxcl1、ならびにsmoxおよび/またはid1の発現量に基づく肺癌患者の予後を判定するためのデータ収集方法およびキット |
GB2524948A (en) * | 2014-03-07 | 2015-10-14 | Oxford Gene Technology Operations Ltd | Detecting Increase or Decrease in the Amount of a Nucleic Acid having a Sequence of Interest |
GB201404998D0 (en) * | 2014-03-20 | 2014-05-07 | Univ Birmingham | Atrial fibrillation therapy |
EP3037545A1 (de) * | 2014-12-23 | 2016-06-29 | The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin | DNS-Methylierungstest auf Prostatakrebs |
EP3246415A1 (de) * | 2016-05-18 | 2017-11-22 | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE | Verfahren zur prognose von prostatakrebs |
US11901083B1 (en) | 2021-11-30 | 2024-02-13 | Vignet Incorporated | Using genetic and phenotypic data sets for drug discovery clinical trials |
US11705230B1 (en) | 2021-11-30 | 2023-07-18 | Vignet Incorporated | Assessing health risks using genetic, epigenetic, and phenotypic data sources |
CN114015771A (zh) * | 2022-01-05 | 2022-02-08 | 北京华诺奥美基因医学检验实验室有限公司 | 一种snrpn父源缺失的检测引物组、试剂盒及非诊断目的的检测方法 |
Family Cites Families (30)
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US5585481A (en) | 1987-09-21 | 1996-12-17 | Gen-Probe Incorporated | Linking reagents for nucleotide probes |
US5457183A (en) | 1989-03-06 | 1995-10-10 | Board Of Regents, The University Of Texas System | Hydroxylated texaphyrins |
US5245022A (en) * | 1990-08-03 | 1993-09-14 | Sterling Drug, Inc. | Exonuclease resistant terminally substituted oligonucleotides |
US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
US5565552A (en) | 1992-01-21 | 1996-10-15 | Pharmacyclics, Inc. | Method of expanded porphyrin-oligonucleotide conjugate synthesis |
US5574142A (en) | 1992-12-15 | 1996-11-12 | Microprobe Corporation | Peptide linkers for improved oligonucleotide delivery |
SE501439C2 (sv) | 1993-06-22 | 1995-02-13 | Pharmacia Lkb Biotech | Sätt och anordning för analys av polynukleotidsekvenser |
DE69417918T2 (de) | 1993-11-30 | 2000-01-05 | Univ Montreal Mcgill | Dna methyltransferase inhibierung |
US5597696A (en) * | 1994-07-18 | 1997-01-28 | Becton Dickinson And Company | Covalent cyanine dye oligonucleotide conjugates |
US5514758A (en) | 1994-09-30 | 1996-05-07 | The Goodyear Tire & Rubber Company | Process for making latex for high performance masking tape |
US6017704A (en) | 1996-06-03 | 2000-01-25 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
US5786146A (en) | 1996-06-03 | 1998-07-28 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
AU7829398A (en) * | 1997-06-09 | 1998-12-30 | University Of Southern California | A cancer diagnostic method based upon dna methylation differences |
DE19754482A1 (de) | 1997-11-27 | 1999-07-01 | Epigenomics Gmbh | Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke |
US7700324B1 (en) | 1998-11-03 | 2010-04-20 | The Johns Hopkins University School Of Medicine | Methylated CpG island amplification (MCA) |
US5958773A (en) | 1998-12-17 | 1999-09-28 | Isis Pharmaceuticals Inc. | Antisense modulation of AKT-1 expression |
US6331393B1 (en) * | 1999-05-14 | 2001-12-18 | University Of Southern California | Process for high-throughput DNA methylation analysis |
US6783933B1 (en) * | 1999-09-15 | 2004-08-31 | The Johns Hopkins University School Of Medicine | CACNA1G polynucleotide, polypeptide and methods of use therefor |
AU2002214576A1 (en) * | 2000-10-13 | 2002-04-22 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Genes related to development of refractory prostate cancer |
CA2439854A1 (en) * | 2001-03-01 | 2002-09-12 | Epigenomics Ag | Method for the development of gene panels for diagnostic and therapeutic purposes based on the expression and methylatoin status of the genes |
DE60211324T2 (de) * | 2001-03-01 | 2007-02-08 | Epigenomics Ag | Verfahren und rechnerprogrammprodukte zur erfassung der biologischen wirkung und/oder aktivität von arzneimitteln, chemischen substanzen und/oder pharmazeuitschen verbindungen auf der basis ihrer effekte auf den methylierungszustand der dna |
EP1410304A2 (de) * | 2001-03-26 | 2004-04-21 | Epigenomics AG | Verfahren zur epigenetischen merkmalauswahl |
US7473767B2 (en) * | 2001-07-03 | 2009-01-06 | The Institute For Systems Biology | Methods for detection and quantification of analytes in complex mixtures |
US20060024684A1 (en) * | 2002-10-01 | 2006-02-02 | Epigenomics Ag | Prognostic markers for prediction of treatment response and/or survival of breast cell proliferative disorder patients |
ATE437962T1 (de) * | 2002-10-01 | 2009-08-15 | Epigenomics Ag | Verfahren für die behandlung von proliferativen erkrankungen von brustzellen |
SE524468C2 (sv) * | 2002-12-09 | 2004-08-10 | Axlon Int Ab | Anordning och metod för sortering av mynt |
US20040146868A1 (en) * | 2003-01-24 | 2004-07-29 | Epigenomics Ag | Methods and nucleic acids for the analysis of CpG dinucleotide methylation status associated with the development of peripheral zone prostate cancer |
ES2801379T3 (es) | 2003-12-01 | 2021-01-11 | Epigenomics Ag | Métodos y ácidos nucleicos para el análisis de la expresión génica asociada con el desarrollo de trastornos proliferativos de células de próstata |
US9017944B2 (en) | 2003-12-11 | 2015-04-28 | Epigenomics Ag | Methods for the prognosis of breast cancer |
EP1826278A1 (de) * | 2006-02-28 | 2007-08-29 | Epiontis GmbH | Epigenetische Modifikation der Loci für CAMTA1 und/oder FOXP3 als Markierung für die Krebsbehandlung |
-
2005
- 2005-12-02 AU AU2005322435A patent/AU2005322435B2/en not_active Ceased
- 2005-12-02 AT AT05853011T patent/ATE438740T1/de not_active IP Right Cessation
- 2005-12-02 ES ES10177053.5T patent/ES2534139T3/es active Active
- 2005-12-02 JP JP2007544601A patent/JP5745202B2/ja not_active Expired - Fee Related
- 2005-12-02 ES ES05853011T patent/ES2331146T3/es active Active
- 2005-12-02 CA CA002593546A patent/CA2593546A1/en not_active Abandoned
- 2005-12-02 EP EP05853011A patent/EP1831399B1/de not_active Not-in-force
- 2005-12-02 DE DE602005015893T patent/DE602005015893D1/de active Active
- 2005-12-02 EP EP10177065A patent/EP2284279A1/de not_active Withdrawn
- 2005-12-02 WO PCT/US2005/043974 patent/WO2006071466A2/en active Application Filing
- 2005-12-02 EP EP10177084A patent/EP2311984A1/de not_active Withdrawn
- 2005-12-02 EP EP10177053.5A patent/EP2280084B1/de not_active Not-in-force
- 2005-12-02 EP EP09010002A patent/EP2213749A1/de not_active Withdrawn
- 2005-12-02 US US11/720,744 patent/US20090197250A1/en not_active Abandoned
-
2012
- 2012-02-22 JP JP2012036858A patent/JP5883677B2/ja not_active Expired - Fee Related
-
2015
- 2015-12-23 US US14/757,840 patent/US20160312287A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2006071466A2 (en) | 2006-07-06 |
US20160312287A1 (en) | 2016-10-27 |
ES2534139T3 (es) | 2015-04-17 |
JP2008522590A (ja) | 2008-07-03 |
EP2311984A8 (de) | 2011-12-28 |
AU2005322435A1 (en) | 2006-07-06 |
EP2284279A1 (de) | 2011-02-16 |
JP5745202B2 (ja) | 2015-07-08 |
WO2006071466A8 (en) | 2009-06-18 |
EP2280084A1 (de) | 2011-02-02 |
EP2280084B1 (de) | 2015-02-11 |
EP1831399A2 (de) | 2007-09-12 |
WO2006071466A3 (en) | 2007-03-15 |
EP2213749A1 (de) | 2010-08-04 |
EP2311984A1 (de) | 2011-04-20 |
AU2005322435B2 (en) | 2012-02-23 |
DE602005015893D1 (de) | 2009-09-17 |
US20090197250A1 (en) | 2009-08-06 |
EP1831399B1 (de) | 2009-08-05 |
JP5883677B2 (ja) | 2016-03-15 |
JP2012120538A (ja) | 2012-06-28 |
ES2331146T3 (es) | 2009-12-22 |
CA2593546A1 (en) | 2006-07-06 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |