IL126979A - Antifungal composition with enhanced bioavailability - Google Patents

Antifungal composition with enhanced bioavailability

Info

Publication number
IL126979A
IL126979A IL12697997A IL12697997A IL126979A IL 126979 A IL126979 A IL 126979A IL 12697997 A IL12697997 A IL 12697997A IL 12697997 A IL12697997 A IL 12697997A IL 126979 A IL126979 A IL 126979A
Authority
IL
Israel
Prior art keywords
antifungal composition
enhanced bioavailability
bioavailability
enhanced
antifungal
Prior art date
Application number
IL12697997A
Other languages
English (en)
Other versions
IL126979A0 (en
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL126979A0 publication Critical patent/IL126979A0/xx
Publication of IL126979A publication Critical patent/IL126979A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL12697997A 1996-05-24 1997-05-21 Antifungal composition with enhanced bioavailability IL126979A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65532996A 1996-05-24 1996-05-24
PCT/US1997/019388 WO1998007429A2 (en) 1996-05-24 1997-05-21 Antifungal composition with enhanced bioavailability

Publications (2)

Publication Number Publication Date
IL126979A0 IL126979A0 (en) 1999-09-22
IL126979A true IL126979A (en) 2000-10-31

Family

ID=24628452

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12697997A IL126979A (en) 1996-05-24 1997-05-21 Antifungal composition with enhanced bioavailability

Country Status (28)

Country Link
EP (1) EP0914127B1 (pl)
JP (1) JP3366648B2 (pl)
KR (1) KR100307427B1 (pl)
CN (1) CN1121860C (pl)
AR (1) AR007250A1 (pl)
AT (1) ATE213632T1 (pl)
AU (1) AU719109B2 (pl)
BR (1) BR9711167A (pl)
CA (1) CA2255663C (pl)
CO (1) CO4840511A1 (pl)
CZ (1) CZ293586B6 (pl)
DE (1) DE69710729T2 (pl)
ES (1) ES2169440T3 (pl)
HK (1) HK1017855A1 (pl)
HU (1) HU221371B1 (pl)
ID (1) ID16956A (pl)
IL (1) IL126979A (pl)
MY (1) MY118988A (pl)
NO (1) NO316997B1 (pl)
NZ (1) NZ332699A (pl)
PE (1) PE68898A1 (pl)
PL (1) PL188401B1 (pl)
RU (1) RU2207119C2 (pl)
SK (1) SK281818B6 (pl)
TR (1) TR199802424T2 (pl)
TW (1) TW504390B (pl)
WO (1) WO1998007429A2 (pl)
ZA (1) ZA974428B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2157731B1 (es) * 1998-07-21 2002-05-01 Liconsa Liberacion Controlada Preparacion farmaceutica oral de un compuesto de actividad antifungica y procedimiento para su preparacion.
CA2359945C (en) 1999-11-12 2011-04-26 Abbott Laboratories Inhibitors of crystallization in a solid dispersion
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
DE60216890T2 (de) * 2001-01-26 2007-08-30 Schering Corp. Kombinationen von einem hemmer der sterol-absorption und einem ppar-aktivator zur behandlung von kardiovaskulären indikationen
AU2003230189A1 (en) * 2003-01-29 2004-08-23 Nitin Bhalachandra Dharmadhikari Oral controlled release pharmaceutical composition containing metaxalone as active agent
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
SG10201508982TA (en) * 2010-11-01 2015-12-30 Melinta Therapeutics Inc Pharmaceutical compositions
RU2450807C1 (ru) * 2011-05-11 2012-05-20 Общество с ограниченной ответственностью фирма "Вита" Стабилизированный фармацевтический состав с противогрибковым действием
CN103845292A (zh) * 2012-11-29 2014-06-11 正大天晴药业集团股份有限公司 泊沙康唑微丸及其制备方法
US9763934B2 (en) * 2014-03-05 2017-09-19 Professional Compounding Centers Of America Synergistic effect of poloxamer-based composition and itraconazole on fungus and yeast
TR201620462A2 (tr) 2016-12-31 2018-07-23 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791111A (en) * 1985-12-23 1988-12-13 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
US5039676A (en) * 1990-05-11 1991-08-13 Schering Corporation Tri- and tetra-substituted-oxetanes and tetrahydrofurans and intermediates thereof
ES2159623T3 (es) * 1993-12-21 2001-10-16 Schering Corp Antifungicos de tetrahidrofurano.

Also Published As

Publication number Publication date
ES2169440T3 (es) 2002-07-01
SK281818B6 (sk) 2001-08-06
CZ379098A3 (cs) 1999-03-17
HU221371B1 (en) 2002-09-28
TW504390B (en) 2002-10-01
RU2207119C2 (ru) 2003-06-27
SK160898A3 (en) 1999-05-07
PL188401B1 (pl) 2005-01-31
WO1998007429A2 (en) 1998-02-26
KR100307427B1 (ko) 2001-12-28
AU719109B2 (en) 2000-05-04
AU5939998A (en) 1998-03-06
PL330480A1 (en) 1999-05-24
NO985447L (no) 1998-11-23
NO985447D0 (no) 1998-11-23
IL126979A0 (en) 1999-09-22
CA2255663C (en) 2002-08-20
EP0914127A2 (en) 1999-05-12
BR9711167A (pt) 1999-08-17
CZ293586B6 (cs) 2004-06-16
CA2255663A1 (en) 1998-02-26
ATE213632T1 (de) 2002-03-15
JP3366648B2 (ja) 2003-01-14
AR007250A1 (es) 1999-10-27
NO316997B1 (no) 2004-07-19
ZA974428B (en) 1997-11-24
PE68898A1 (es) 1998-11-10
TR199802424T2 (xx) 1999-03-22
MY118988A (en) 2005-02-28
CN1121860C (zh) 2003-09-24
CO4840511A1 (es) 1999-09-27
JP2000509720A (ja) 2000-08-02
HUP9904265A2 (hu) 2000-04-28
NZ332699A (en) 2000-01-28
WO1998007429A3 (en) 1998-04-23
EP0914127B1 (en) 2002-02-27
HUP9904265A3 (en) 2000-05-29
HK1017855A1 (en) 1999-12-03
KR20000065222A (ko) 2000-11-06
ID16956A (id) 1997-11-27
CN1228699A (zh) 1999-09-15
DE69710729D1 (de) 2002-04-04
DE69710729T2 (de) 2002-08-14

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