DE69710729T2 - Fungizide zusammensetzung mit erhörter bioverfügbarkeit - Google Patents

Fungizide zusammensetzung mit erhörter bioverfügbarkeit

Info

Publication number
DE69710729T2
DE69710729T2 DE69710729T DE69710729T DE69710729T2 DE 69710729 T2 DE69710729 T2 DE 69710729T2 DE 69710729 T DE69710729 T DE 69710729T DE 69710729 T DE69710729 T DE 69710729T DE 69710729 T2 DE69710729 T2 DE 69710729T2
Authority
DE
Germany
Prior art keywords
heared
bioavailability
fungicidal composition
fungicidal
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69710729T
Other languages
English (en)
Other versions
DE69710729D1 (de
Inventor
A Sangekar
A Vadino
I Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DE69710729D1 publication Critical patent/DE69710729D1/de
Publication of DE69710729T2 publication Critical patent/DE69710729T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69710729T 1996-05-24 1997-05-21 Fungizide zusammensetzung mit erhörter bioverfügbarkeit Expired - Lifetime DE69710729T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65532996A 1996-05-24 1996-05-24
PCT/US1997/019388 WO1998007429A2 (en) 1996-05-24 1997-05-21 Antifungal composition with enhanced bioavailability

Publications (2)

Publication Number Publication Date
DE69710729D1 DE69710729D1 (de) 2002-04-04
DE69710729T2 true DE69710729T2 (de) 2002-08-14

Family

ID=24628452

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69710729T Expired - Lifetime DE69710729T2 (de) 1996-05-24 1997-05-21 Fungizide zusammensetzung mit erhörter bioverfügbarkeit

Country Status (28)

Country Link
EP (1) EP0914127B1 (de)
JP (1) JP3366648B2 (de)
KR (1) KR100307427B1 (de)
CN (1) CN1121860C (de)
AR (1) AR007250A1 (de)
AT (1) ATE213632T1 (de)
AU (1) AU719109B2 (de)
BR (1) BR9711167A (de)
CA (1) CA2255663C (de)
CO (1) CO4840511A1 (de)
CZ (1) CZ293586B6 (de)
DE (1) DE69710729T2 (de)
ES (1) ES2169440T3 (de)
HK (1) HK1017855A1 (de)
HU (1) HU221371B1 (de)
ID (1) ID16956A (de)
IL (1) IL126979A (de)
MY (1) MY118988A (de)
NO (1) NO316997B1 (de)
NZ (1) NZ332699A (de)
PE (1) PE68898A1 (de)
PL (1) PL188401B1 (de)
RU (1) RU2207119C2 (de)
SK (1) SK281818B6 (de)
TR (1) TR199802424T2 (de)
TW (1) TW504390B (de)
WO (1) WO1998007429A2 (de)
ZA (1) ZA974428B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2157731B1 (es) * 1998-07-21 2002-05-01 Liconsa Liberacion Controlada Preparacion farmaceutica oral de un compuesto de actividad antifungica y procedimiento para su preparacion.
EP1175205B1 (de) 1999-11-12 2006-06-14 Abbott Laboratories Feste dispersion mit ritonavir, fenofibrat oder griseofulvin
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
DK1413331T3 (da) * 2001-01-26 2007-12-10 Schering Corp Kombinationer af peroxisomproliferatoraktiveret receptor (PPAR)-aktivatoren fenofibrat og sterolabsorptionsinhibitoren ezetimib til vaskulære indikationer
WO2004066981A1 (en) * 2003-01-29 2004-08-12 Sun Pharmaceutical Industries Limited Oral controlled release pharmaceutical composition containing metaxalone as active agent
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
SG190117A1 (en) 2010-11-01 2013-06-28 Rib X Pharmaceuticals Inc Pharmaceutical compositions
RU2450807C1 (ru) * 2011-05-11 2012-05-20 Общество с ограниченной ответственностью фирма "Вита" Стабилизированный фармацевтический состав с противогрибковым действием
CN103845292A (zh) * 2012-11-29 2014-06-11 正大天晴药业集团股份有限公司 泊沙康唑微丸及其制备方法
US9763934B2 (en) * 2014-03-05 2017-09-19 Professional Compounding Centers Of America Synergistic effect of poloxamer-based composition and itraconazole on fungus and yeast
TR201620462A2 (tr) 2016-12-31 2018-07-23 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791111A (en) * 1985-12-23 1988-12-13 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
US5039676A (en) * 1990-05-11 1991-08-13 Schering Corporation Tri- and tetra-substituted-oxetanes and tetrahydrofurans and intermediates thereof
CZ294823B6 (cs) * 1993-12-21 2005-03-16 Schering Corporation Fungicidní tetrahydrofurany

Also Published As

Publication number Publication date
PE68898A1 (es) 1998-11-10
ES2169440T3 (es) 2002-07-01
CZ293586B6 (cs) 2004-06-16
MY118988A (en) 2005-02-28
BR9711167A (pt) 1999-08-17
TR199802424T2 (xx) 1999-03-22
IL126979A0 (en) 1999-09-22
KR20000065222A (ko) 2000-11-06
HU221371B1 (en) 2002-09-28
SK281818B6 (sk) 2001-08-06
AR007250A1 (es) 1999-10-27
HUP9904265A3 (en) 2000-05-29
HK1017855A1 (en) 1999-12-03
PL330480A1 (en) 1999-05-24
CA2255663A1 (en) 1998-02-26
AU719109B2 (en) 2000-05-04
WO1998007429A3 (en) 1998-04-23
NZ332699A (en) 2000-01-28
JP3366648B2 (ja) 2003-01-14
CN1121860C (zh) 2003-09-24
ID16956A (id) 1997-11-27
CA2255663C (en) 2002-08-20
AU5939998A (en) 1998-03-06
CO4840511A1 (es) 1999-09-27
TW504390B (en) 2002-10-01
ZA974428B (en) 1997-11-24
RU2207119C2 (ru) 2003-06-27
NO985447D0 (no) 1998-11-23
ATE213632T1 (de) 2002-03-15
NO316997B1 (no) 2004-07-19
IL126979A (en) 2000-10-31
NO985447L (no) 1998-11-23
CZ379098A3 (cs) 1999-03-17
JP2000509720A (ja) 2000-08-02
WO1998007429A2 (en) 1998-02-26
SK160898A3 (en) 1999-05-07
DE69710729D1 (de) 2002-04-04
CN1228699A (zh) 1999-09-15
HUP9904265A2 (hu) 2000-04-28
EP0914127A2 (de) 1999-05-12
KR100307427B1 (ko) 2001-12-28
EP0914127B1 (de) 2002-02-27
PL188401B1 (pl) 2005-01-31

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