IL123889A0 - Pharmaceutical angiostatic dipeptide compositions and methods of use thereof - Google Patents
Pharmaceutical angiostatic dipeptide compositions and methods of use thereofInfo
- Publication number
- IL123889A0 IL123889A0 IL12388996A IL12388996A IL123889A0 IL 123889 A0 IL123889 A0 IL 123889A0 IL 12388996 A IL12388996 A IL 12388996A IL 12388996 A IL12388996 A IL 12388996A IL 123889 A0 IL123889 A0 IL 123889A0
- Authority
- IL
- Israel
- Prior art keywords
- methods
- pharmaceutical
- angiostatic
- dipeptide
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53870195A | 1995-10-03 | 1995-10-03 | |
| US08/614,764 US5902790A (en) | 1995-10-03 | 1996-03-13 | Pharmaceutical angiostatic dipeptide compositions and method of use thereof |
| PCT/US1996/015856 WO1997012625A1 (en) | 1995-10-03 | 1996-10-02 | Pharmaceutical angiostatic dipeptide compositions and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL123889A0 true IL123889A0 (en) | 1998-10-30 |
Family
ID=27065900
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12388996A IL123889A0 (en) | 1995-10-03 | 1996-10-02 | Pharmaceutical angiostatic dipeptide compositions and methods of use thereof |
Country Status (23)
| Country | Link |
|---|---|
| US (4) | US5902790A (cs) |
| EP (1) | EP0869808B1 (cs) |
| JP (2) | JP3679129B2 (cs) |
| KR (1) | KR100483779B1 (cs) |
| CN (1) | CN1128636C (cs) |
| AT (1) | ATE332702T1 (cs) |
| AU (1) | AU714846B2 (cs) |
| BR (1) | BR9610838A (cs) |
| CA (1) | CA2233457C (cs) |
| CZ (1) | CZ298345B6 (cs) |
| DE (1) | DE69636343T2 (cs) |
| DK (1) | DK0869808T3 (cs) |
| EA (1) | EA001146B1 (cs) |
| ES (1) | ES2268710T3 (cs) |
| HU (1) | HUP9902105A3 (cs) |
| IL (1) | IL123889A0 (cs) |
| MX (1) | MX9802564A (cs) |
| NO (1) | NO326298B1 (cs) |
| NZ (1) | NZ319907A (cs) |
| PL (1) | PL186123B1 (cs) |
| SK (1) | SK283677B6 (cs) |
| TR (1) | TR199800653T1 (cs) |
| WO (1) | WO1997012625A1 (cs) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5902790A (en) * | 1995-10-03 | 1999-05-11 | Cytran, Inc. | Pharmaceutical angiostatic dipeptide compositions and method of use thereof |
| US6060452A (en) * | 1996-03-13 | 2000-05-09 | Cytran, Inc. | Analogs of L-Glu-L-Trp having pharmacological activity |
| AU3467099A (en) * | 1998-04-03 | 1999-10-25 | Cytran Ltd. | Methods for production of therapeutic cytokines |
| US6555543B2 (en) | 2000-08-04 | 2003-04-29 | Dmi Biosciences, Inc. | Method of using diketopiperazines and composition containing them |
| CN100579582C (zh) * | 2001-01-02 | 2010-01-13 | Imtm股份有限公司 | 联合应用酶抑制剂及其药学组合物在制备治疗和预防动脉硬化、预防和治疗根据杰尔－库姆斯分类法分类的ⅰ型过敏反应以及治疗和预防与毛囊和表皮角化过度和角质细胞的过度增殖相关的皮肤疾病的药物中的用途 |
| DE10100052A1 (de) * | 2001-01-02 | 2002-07-11 | Inst Medizintechnologie Magdeb | Kombinierte Verwendung von Enzyminhibitoren und pharmazeutischen Zubereitungen daraus zur Therapie und Prophylaxe der Atheriosklerose |
| US20030087830A1 (en) * | 2001-06-12 | 2003-05-08 | Eric Dupont | Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof |
| KR20150080004A (ko) | 2003-05-15 | 2015-07-08 | 앰피오 파마슈티컬스 인코퍼레이티드 | Ｔ-세포 매개성 질환의 치료 방법 |
| WO2005016326A2 (en) * | 2003-07-11 | 2005-02-24 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Analogs of thalidomide as potential angiogenesis inhibitors |
| CA2808646C (en) | 2003-09-17 | 2016-08-23 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Thalidomide analogs as tnf-alpha modulators |
| US8952895B2 (en) | 2011-06-03 | 2015-02-10 | Apple Inc. | Motion-based device operations |
| EP1848541A4 (en) * | 2005-02-07 | 2013-01-16 | Pharmalight Inc | METHOD AND DEVICE FOR OPHTHALMIC DELIVERY OF PHARMACEUTICALLY ACTIVE INGREDIENTS |
| CA2569204A1 (en) * | 2006-11-28 | 2008-05-28 | Apotex Technologies Inc. | Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan |
| CA2571645A1 (en) * | 2006-12-19 | 2008-06-19 | Apotex Technologies Inc. | Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture |
| US7906486B2 (en) * | 2007-02-13 | 2011-03-15 | Sciclone Pharmaceuticals, Inc. | Method of treating or preventing tissue deterioration, injury or damage due to disease of mucosa |
| CA2579119C (en) * | 2007-02-16 | 2013-03-05 | Apotex Technologies Inc. | Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan |
| NZ584065A (en) * | 2007-08-23 | 2012-03-30 | Sciclone Pharmaceuticals Inc | Treatment of lung cancer with scv-07 |
| JP5856843B2 (ja) | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ，インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| DE102008032828A1 (de) * | 2008-07-02 | 2010-01-07 | Technische Universität Dresden | Tryptophanhaltige Peptide aus alpha-Lactalbumin mit blutdrucksenkender und vasoprotektiver Wirkung für biofunktionelle Lebensmittel |
| CA2810844C (en) | 2010-09-07 | 2017-03-21 | Dmi Acquisition Corp. | Diketopiperazine compositions for the treatment of metabolic syndrome and related conditions |
| MY172699A (en) | 2011-10-10 | 2019-12-10 | Ampio Pharmaceuticals Inc | Implantable medical devices with increased immune tolerance, and methods for making and implanting |
| WO2013055734A1 (en) | 2011-10-10 | 2013-04-18 | Ampio Pharmaceuticals, Inc. | Treatment of degenerative joint disease |
| MX355446B (es) | 2011-10-28 | 2018-04-18 | Ampio Pharmaceuticals Inc | Tratamiento de rinitis. |
| US8927725B2 (en) | 2011-12-02 | 2015-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Thio compounds |
| CN102631464B (zh) * | 2012-05-18 | 2013-07-31 | 崔新明 | 一种治疗婴幼儿血管瘤的中药膏剂及其制备方法 |
| EP2968315B1 (en) | 2013-03-15 | 2020-06-03 | Ampio Pharmaceuticals, Inc. | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
| WO2016028790A1 (en) | 2014-08-18 | 2016-02-25 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
| US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9744239B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US11389512B2 (en) | 2015-06-22 | 2022-07-19 | Ampio Pharmaceuticals, Inc. | Use of low molecular weight fractions of human serum albumin in treating diseases |
| SG11202001595SA (en) | 2017-08-31 | 2020-03-30 | Singapore Health Serv Pte Ltd | Angio-3 for treatment of retinal angiogenic diseases |
| CN116874557A (zh) * | 2023-08-01 | 2023-10-13 | 首都医科大学 | 2-Trp-AA-四氢咔啉-3-羧酸类化合物及其PAF抑制剂的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3997516A (en) * | 1974-07-04 | 1976-12-14 | Takeda Chemical Industries, Ltd. | Method for protecting guanidino group and restoring the same |
| US4191753A (en) * | 1978-11-06 | 1980-03-04 | University Of Miami | Anti-hypertensive peptide analogs |
| US5728680A (en) * | 1987-12-30 | 1998-03-17 | Cytoven J.V. | Methods for normalizing numbers of lymphocytes |
| JP2511159B2 (ja) * | 1987-12-30 | 1996-06-26 | オブシェストボ エス オグラニチェンノイ オトベツベンノスチュ “ツィトメド―ペプトス” | 免疫欠損状態の治療のための医薬製剤 |
| GR1000608B (el) * | 1988-07-21 | 1992-08-31 | Erba Carlo Spa | Μεθοδος για την παρασκευη ανταγωνιστων bombesin. |
| SU1642398A1 (ru) * | 1988-12-21 | 1991-04-15 | Ростовский медицинский институт | Способ лечени синуитов у детей |
| US5902790A (en) * | 1995-10-03 | 1999-05-11 | Cytran, Inc. | Pharmaceutical angiostatic dipeptide compositions and method of use thereof |
| US5770576A (en) * | 1989-08-30 | 1998-06-23 | Cytran, Inc. | Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity |
| RU1827255C (ru) * | 1990-10-22 | 1993-07-15 | Киевский государственный институт усовершенствования врачей | Способ лечени туберкулеза легких |
| JP3068656B2 (ja) * | 1991-03-07 | 2000-07-24 | アピ株式会社 | 新規なペプチド及びアンジオテンシン変換酵素阻害ペプチド並びにそれらを含有する経口摂食組成物 |
| CA2107460A1 (en) * | 1991-04-01 | 1992-10-02 | Vladimir K. Khavinson | Pharmaceutical dipeptide compositions and methods of use thereof |
| RU2014063C1 (ru) * | 1991-04-23 | 1994-06-15 | Сочинский научно-исследовательский институт курортологии и физиотерапии | Способ лечения подострых воспалительных заболеваний гениталий |
| ATE188219T1 (de) * | 1991-10-28 | 2000-01-15 | Cytran Ltd | Pharmazeutische dipeptid zusammensetzungen und verwendungsmethoden. |
| WO1995003067A1 (en) * | 1993-07-21 | 1995-02-02 | Khavinson Vladimir Khatskelevi | Pharmaceutical with immunomodulating activity |
| JPH09503205A (ja) * | 1993-09-24 | 1997-03-31 | ザ ユニバーシティ オブ サザーン カリフォルニア | 組織修復におけるアンギオテンシン▲ｉｉ▼類似体の使用 |
-
1996
- 1996-03-13 US US08/614,764 patent/US5902790A/en not_active Expired - Lifetime
- 1996-10-02 IL IL12388996A patent/IL123889A0/xx unknown
- 1996-10-02 BR BR9610838-0A patent/BR9610838A/pt not_active Application Discontinuation
- 1996-10-02 AT AT96934021T patent/ATE332702T1/de not_active IP Right Cessation
- 1996-10-02 HU HU9902105A patent/HUP9902105A3/hu unknown
- 1996-10-02 CZ CZ0091398A patent/CZ298345B6/cs not_active IP Right Cessation
- 1996-10-02 TR TR1998/00653T patent/TR199800653T1/xx unknown
- 1996-10-02 SK SK423-98A patent/SK283677B6/sk not_active IP Right Cessation
- 1996-10-02 ES ES96934021T patent/ES2268710T3/es not_active Expired - Lifetime
- 1996-10-02 NZ NZ319907A patent/NZ319907A/xx not_active IP Right Cessation
- 1996-10-02 EP EP96934021A patent/EP0869808B1/en not_active Expired - Lifetime
- 1996-10-02 EA EA199800357A patent/EA001146B1/ru not_active IP Right Cessation
- 1996-10-02 DK DK96934021T patent/DK0869808T3/da active
- 1996-10-02 PL PL96326149A patent/PL186123B1/pl unknown
- 1996-10-02 KR KR1019980702431A patent/KR100483779B1/ko not_active IP Right Cessation
- 1996-10-02 WO PCT/US1996/015856 patent/WO1997012625A1/en active IP Right Grant
- 1996-10-02 JP JP51441597A patent/JP3679129B2/ja not_active Expired - Lifetime
- 1996-10-02 CN CN96197430A patent/CN1128636C/zh not_active Expired - Lifetime
- 1996-10-02 CA CA002233457A patent/CA2233457C/en not_active Expired - Lifetime
- 1996-10-02 DE DE69636343T patent/DE69636343T2/de not_active Expired - Lifetime
- 1996-10-02 AU AU72540/96A patent/AU714846B2/en not_active Expired
-
1998
- 1998-03-30 NO NO19981436A patent/NO326298B1/no not_active IP Right Cessation
- 1998-04-01 MX MX9802564A patent/MX9802564A/es unknown
-
1999
- 1999-03-01 US US09/260,190 patent/US6096713A/en not_active Expired - Lifetime
-
2000
- 2000-02-17 US US09/506,430 patent/US6911431B1/en not_active Expired - Fee Related
-
2005
- 2005-03-15 JP JP2005074079A patent/JP2005194287A/ja not_active Withdrawn
- 2005-05-16 US US11/129,367 patent/US20060094665A1/en not_active Abandoned
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