IL118485A - 5,6-dihydro-9H-pyrazolo¬3,4-c¾-1,2,4-triazolo¬4,3-a¾ pyridines and pharmaceutical compositions containing them - Google Patents

5,6-dihydro-9H-pyrazolo¬3,4-c¾-1,2,4-triazolo¬4,3-a¾ pyridines and pharmaceutical compositions containing them

Info

Publication number
IL118485A
IL118485A IL11848596A IL11848596A IL118485A IL 118485 A IL118485 A IL 118485A IL 11848596 A IL11848596 A IL 11848596A IL 11848596 A IL11848596 A IL 11848596A IL 118485 A IL118485 A IL 118485A
Authority
IL
Israel
Prior art keywords
triazolo
pyrazolo
pyridines
dihydro
pharmaceutical compositions
Prior art date
Application number
IL11848596A
Other languages
English (en)
Other versions
IL118485A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL118485A0 publication Critical patent/IL118485A0/xx
Publication of IL118485A publication Critical patent/IL118485A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL11848596A 1995-06-06 1996-05-30 5,6-dihydro-9H-pyrazolo¬3,4-c¾-1,2,4-triazolo¬4,3-a¾ pyridines and pharmaceutical compositions containing them IL118485A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/IB1995/000429 WO1996039408A1 (en) 1995-06-06 1995-06-06 TRICYCLIC 5,6-DIHYDRO-9H-PYRAZOLO[3,4-c]-1,2,4-TRIAZOLO[4,3-α]PYRIDINES
CA002223624A CA2223624C (en) 1995-06-06 1995-06-06 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-.alpha.]pyridines
HU9601541A HUP9601541A3 (en) 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
IL118485A0 IL118485A0 (en) 1996-09-12
IL118485A true IL118485A (en) 2000-02-17

Family

ID=89994031

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11848596A IL118485A (en) 1995-06-06 1996-05-30 5,6-dihydro-9H-pyrazolo¬3,4-c¾-1,2,4-triazolo¬4,3-a¾ pyridines and pharmaceutical compositions containing them

Country Status (43)

Country Link
US (1) US6004974A (ko)
EP (1) EP0837860B1 (ko)
JP (1) JP3107827B2 (ko)
KR (2) KR100191972B1 (ko)
CN (1) CN1061044C (ko)
AP (1) AP609A (ko)
AR (1) AR002745A1 (ko)
AT (1) ATE214700T1 (ko)
AU (1) AU694871B2 (ko)
BG (1) BG62568B1 (ko)
BR (1) BR9602627A (ko)
CA (1) CA2223624C (ko)
CO (1) CO4700460A1 (ko)
CZ (1) CZ287251B6 (ko)
DE (1) DE69525978T2 (ko)
DK (1) DK0837860T3 (ko)
DZ (1) DZ2044A1 (ko)
ES (1) ES2172583T3 (ko)
FI (1) FI114097B (ko)
HR (1) HRP960268B1 (ko)
HU (1) HUP9601541A3 (ko)
IL (1) IL118485A (ko)
IS (1) IS1913B (ko)
LV (1) LV11620B (ko)
MA (1) MA23893A1 (ko)
MX (1) MX9709897A (ko)
MY (1) MY116527A (ko)
NO (1) NO306256B1 (ko)
NZ (1) NZ286734A (ko)
OA (1) OA10458A (ko)
PL (1) PL184195B1 (ko)
PT (1) PT837860E (ko)
RO (1) RO115881B1 (ko)
RU (1) RU2161158C2 (ko)
SA (1) SA96170065B1 (ko)
SG (1) SG54341A1 (ko)
SI (1) SI9600186A (ko)
SK (1) SK282167B6 (ko)
TN (1) TNSN96083A1 (ko)
TR (1) TR199600482A1 (ko)
TW (1) TW460469B (ko)
WO (1) WO1996039408A1 (ko)
YU (1) YU49346B (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2792938B1 (fr) 1999-04-28 2001-07-06 Warner Lambert Co NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
EP1380585B1 (en) * 1999-04-30 2004-11-10 Pfizer Products Inc. Pyrazolopyridinone as intermediate
US6326495B2 (en) * 1999-04-30 2001-12-04 Pfizer Inc. Process for preparing 8-cyclopentyl-6-ethyl-3-[substituted]-5,8-dihydro-4H-1,2,3a,7,8-pentaaza-as-indacenes and intermediates useful therein
PT1212089E (pt) 1999-08-21 2006-08-31 Altana Pharma Ag Combinacao sinergica de roflumilast e salmeterol
EP1265861A2 (en) 2000-03-16 2002-12-18 Inflazyme Pharmaceuticals, Ltd. Benzylated pde4 inhibitors
NZ529335A (en) * 2001-05-25 2005-09-30 Pfizer A PDE 4 inhibitor and an anti-cholinergic agent in combination for treating obstructive airways diseases
EP1397135B1 (en) * 2001-05-25 2006-12-06 Boehringer Ingelheim Pharma GmbH & Co.KG Combination of a pde4 inhibitor and tiotropium or derivative thereof for treating obstructive airways
GB0122031D0 (en) * 2001-09-12 2001-10-31 Pfizer Ltd Use of pde4 inhibitors in a dry powder inhaler
GB0129395D0 (en) * 2001-12-07 2002-01-30 Pfizer Ltd Pharmaceutical combination
US20050107420A1 (en) * 2002-05-23 2005-05-19 Boehringe Ingelheim Pharma Gmbh & Co. Kg Combination of a PDE4 inhibitor and tiotropium or derivative thereof for treating obstructive airways and other inflammatory diseases
WO2006075748A1 (ja) * 2005-01-17 2006-07-20 Santen Pharmaceutical Co., Ltd. アレルギー性結膜疾患治療剤
WO2007045979A1 (en) 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Pharmaceutical compositions of muscarinic receptor antagonists
RS53461B (en) 2006-07-05 2014-12-31 Takeda Gmbh COMBINATION OF HMG-COA REDUCTASE INHIBITOR OR SIMVASTATIN WITH PHOSPHODIESTERASE 4 INHIBITOR AS A ROFLUMILAST FOR THE TREATMENT OF INFLAMMATORY PULMONARY DISEASES
JP5579724B2 (ja) * 2008-10-17 2014-08-27 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ホスファチジルイノシトール−３−キナーゼ（ｐｉ−３キナーゼ）阻害剤としてのテトラ−アザ−複素環
EP2507244B1 (en) 2009-12-04 2014-11-05 Nerviano Medical Sciences S.r.l. Tricyclopyrazole derivatives
WO2013084182A1 (en) 2011-12-08 2013-06-13 Glenmark Pharmaceuticals S.A. Pharmaceutical composition that includes a pde4 enzyme inhibitor and an analgesic agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697532A (en) * 1970-08-12 1972-10-10 Squibb & Sons Inc 5-methyldipyrazolo {8 3,4-b;3{40 ,4{40 -d{9 {0 pyridin-3(2h)-ones
RU2131876C1 (ru) * 1993-07-06 1999-06-20 Пфайзер Инк. Бициклические тетрагидропиразолпиридины или их фармацевтически приемлемые соли, фармацевтическая композиция, способ ингибирования фосфодиэстеразы, способ лечения
CA2143143A1 (en) * 1994-03-08 1995-09-09 Toshihiko Tanaka 3-phenylpyrrolidine derivatives

Also Published As

Publication number Publication date
NO962320D0 (no) 1996-06-05
KR100225719B1 (en) 1999-10-15
DE69525978D1 (de) 2002-04-25
AU5477396A (en) 1996-12-19
NZ286734A (en) 1998-02-26
RO115881B1 (ro) 2000-07-28
JP3107827B2 (ja) 2000-11-13
EP0837860A1 (en) 1998-04-29
DK0837860T3 (da) 2002-05-27
ES2172583T3 (es) 2002-10-01
WO1996039408A1 (en) 1996-12-12
TW460469B (en) 2001-10-21
MX9709897A (es) 1998-03-31
CZ287251B6 (en) 2000-10-11
RU2161158C2 (ru) 2000-12-27
MA23893A1 (fr) 1996-12-31
HU9601541D0 (en) 1996-07-29
PT837860E (pt) 2002-07-31
SA96170065B1 (ar) 2005-12-21
CZ162696A3 (en) 1997-01-15
HUP9601541A3 (en) 1997-05-28
US6004974A (en) 1999-12-21
DZ2044A1 (fr) 2002-07-21
PL314459A1 (en) 1996-12-09
YU34696A (sh) 1999-07-28
SI9600186A (en) 1997-04-30
EP0837860B1 (en) 2002-03-20
ATE214700T1 (de) 2002-04-15
CO4700460A1 (es) 1998-12-29
CN1061044C (zh) 2001-01-24
DE69525978T2 (de) 2002-12-19
BG100640A (bg) 1997-03-31
NO962320L (no) 1996-12-09
IS1913B (is) 2004-02-03
AU694871B2 (en) 1998-07-30
YU49346B (sh) 2005-07-19
FI974434A (fi) 1997-12-05
CA2223624A1 (en) 1996-12-12
LV11620B (en) 1997-04-20
TR199600482A1 (tr) 1997-03-21
LV11620A (lv) 1996-12-20
BG62568B1 (bg) 2000-02-29
JPH10510242A (ja) 1998-10-06
AP9600806A0 (en) 1996-07-31
HRP960268A2 (en) 1997-08-31
MY116527A (en) 2004-02-28
TNSN96083A1 (fr) 2005-03-15
SK282167B6 (sk) 2001-11-06
FI114097B (fi) 2004-08-13
AP609A (en) 1997-09-03
CA2223624C (en) 2001-02-20
IL118485A0 (en) 1996-09-12
OA10458A (en) 2002-03-27
SG54341A1 (en) 1998-11-16
KR970003440A (ko) 1997-01-28
BR9602627A (pt) 1998-09-01
AR002745A1 (es) 1998-04-29
PL184195B1 (pl) 2002-09-30
FI974434A0 (fi) 1997-12-05
HUP9601541A2 (en) 1997-02-28
IS4350A (is) 1996-12-07
SK71896A3 (en) 1997-05-07
NO306256B1 (no) 1999-10-11
HRP960268B1 (en) 2002-12-31
CN1142499A (zh) 1997-02-12
KR100191972B1 (ko) 1999-06-15

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Legal Events

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KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees